Shedding light on biochemical changes in single neuron-like pheochromocytoma cells following exposure to synchrotron sourced terahertz radiation using synchrotron source Fourier tr... by Palalle G. Tharushi Perera, Jitraporn Vongsvivut, Denver Linklater, Zoltan Vilagosh, Dominique Appadoo, The Hong Phong Nguyen, Mark J. Tobin, Rodney Croft, Elena P. Ivanova

“…The outcome of this study re-emphasized the exceptional SS FTIR capability to perform single-cell analysis directly, providing (i) unique biological information on cell variability within the population as well as between different groups, and (ii) evidence of molecular changes in the exposed cells that could lead to a deeper understanding of the effect of THz exposure at a single-cell level.…”
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INFLUENCIA DE FACTORES EDAFO/CLIMÁTICOS SOBRE POBLACIONES MICROBIANAS DE SUELOS ÁRIDOS CON AGRICULTURA BAJO RIEGO by Lujan Masseroni, María Micaela Pérez, Paolo Daniel Sartor, Laura Marcela Rörig, Luciano José Merini

“…Se realizó un análisis fisicoquímico de los suelos, se registró la temperatura y humedad, así como la actividad biológica total (hidrólisis FDA) y la huella molecular (DGGE y T-RFLP) para cada tratamiento. Los análisis fisicoquímicos del suelo muestran que las prácticas agrícolas mejoraron algunas de las propiedades edáficas como el nivel de materia orgánica, aunque el aporte de agua en cantidades limitadas (riego presurizado) provocó un aumento de la conductividad eléctrica. …”
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Dynamics and Insights into the Unique Ecological Guild of Fungi in Bacteria-Bioaugmented Anaerobic Digesters by Linda U. Obi, Ashira Roopnarain, Memory Tekere, Jun Zhou, Heng Li, Yuanpeng Wang, Yanlong Zhang, Rasheed A. Adeleke

“…While bacterial and archaeal communities have been well explored using molecular techniques, fungal community structures remain relatively understudied. …”
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CtBP1 is essential for epigenetic silencing of μ-opioid receptor genes in the dorsal root ganglion in spinal nerve ligation-induced neuropathic pain by Cheng-Yuan Lai, Ming-Chun Hsieh, Chou-Ming Yeh, Tzer-Bin Lin, Dylan Chou, Hsueh-Hsiao Wang, Kuan-Hung Lin, Jen-Kun Cheng, Po-Sheng Yang, Hsien-Yu Peng

“…However, the underlying molecular mechanisms of CtBP1-mediated epigenetic regulation in DRG neurons in neuropathic pain remain poorly elucidated. …”
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Trends in survival of patients with stage I/II Burkitt lymphoma in the United States: A SEER database analysis by Ze‐Long Liu, Pan‐Pan Liu, Xi‐Wen Bi, De‐Xin Lei, Yu Wang, Zhi‐Ming Li, Wen‐Qi Jiang, Yi Xia

“…In conclusion, the prognosis of patients with limited‐stage BL has improved in the 2002‐2014 era, but the outcome was still much poorer in elderly patients, which needs to be improved by identifying newly molecular‐targeted drugs and developing novel personalized therapeutic approaches.…”
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ColMA‐based bioprinted 3D scaffold allowed to study tenogenic events in human tendon stem cells by Giacomo Cortella, Erwin Pavel Lamparelli, Maria Camilla Ciardulli, Joseph Lovecchio, Emanuele Giordano, Nicola Maffulli, Giovanna Della Porta

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LncRNA-ANRIL regulates CDKN2A to promote malignant proliferation of Kasumi-1 cells by Jianxia Xu, Jingxin Zhang, Chengsi Zhang, Huali Hu, Siqi Wang, Fahua Deng, Wu Zhou, Yuancheng Liu, Chenlong Hu, Hai Huang, Sixi Wei

“…Abstract Objective This study aimed to investigate the regulatory effects of long non-coding RNA-ANRIL on CDKN2A in the cell cycle of Kasumi-1 cells and elucidate the underlying molecular mechanisms. Methods ANRIL and CDKN2A expression levels were quantified using RT-qPCR in peripheral blood samples from acute myeloid leukemia (AML) patients. …”
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Epidemiology and outcomes of carbapenem-resistant Klebsiella pneumoniae infections in patients with hematological malignancies from 2014 to 2022 by Meng Li, Liyan Ye, Zhenghao Yu, Hongwu Yao, Yunxi Liu, Guanglei Wang, Mingmei Du

“…The risk factors, epidemiological characteristics, data from all patients with CRKP, NGS gene sequencing molecular epidemiology analysis, and cross-transmission were described.ResultsA total of 217 patients with K. pneumoniae isolates, including 38 (17.5%) patients with CRKP isolates, were confirmed in the HM department. …”
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Genome-wide identification of oat TCP gene family and expression patterns under abiotic stress by Jiaming Nie, Jiaming Nie, Hongbin Zhao, Hongbin Zhao, Hongbin Zhao, Xiaodong Guo, Xiaodong Guo, Tao Zhang, Tao Zhang, Bing Han, Bing Han, Bing Han, Huiyan Liu, Huiyan Liu

“…This study provides insights into the functional characterization of the oat TCP gene family and its molecular mechanisms underlying stress tolerance.…”
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Potential Interaction of Pinocembrin with Drug Transporters and Hepatic Drug-Metabolizing Enzymes by Sirima Sangkapat, Rattiporn Boonnop, Jeerawat Pimta, Napason Chabang, Bodee Nutho, Promsuk Jutabha, Sunhapas Soodvilai

“…Based on the kinetic study and molecular docking, pinocembrin inhibited OAT1 and OAT3 via a competitive inhibition. …”
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Dietary β-Mannanase Affects the Growth, Antioxidant, and Immunes Responses of African Catfish, Clarias gariepinus, and Its Challenge Against Aeromonas hydrophila Infection by Ibrahim Adeshina, Bilal Ahamad Paray, Eijaz Ahmed Bhat, Shahid Sherzada, Olaolu O. Fawole, Dalhatu J. Bawa, Thais Pereira da Cruz, Lateef O. Tiamiyu

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Development of the therapeutic regimen based on the synergistic activity of cyclophosphamide and double-stranded DNA preparation which results in complete cure of mice engrafted wi... by E. A. Potter, E. V. Dolgova, A. S. Proskurina, Ya. R. Efremov, O. S. Taranov, V. P. Nikolin, N. A. Popova, T. D. Dubatolova, D. D. Petrova, E. I. Vereschagin, A. M. Minkevich, O. M. Andrushkevich, S. I. Baiborodin, V. A. Rogachev, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, S. S. Bogachev

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Mitochondria-targeted photothermal-chemodynamic therapy enhances checkpoint blockade immunotherapy on colon cancer by Benchao Zheng, Hongbo Wang, Shiyi Zhai, Jiangsheng Li, Kuangda Lu

“…This effect has been attributed in several studies to the release of damage-associated molecular patterns (DAMPs) triggered by mitochondrial injury. …”
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MsCL-P1: A multifunctional C-type lectin from largemouth bass (Micropterus salmoides) with broad microbe binding and agglutination activities by Siyi She, Ying Ye, Fengyao Guo, Shun Yang, Mengmeng Huang, Hui Fei

“…The recombinant CRD of MsCL-P1 (rCRD) demonstrated binding activity to various pathogen-associated molecular patterns (PAMPs), including lipopolysaccharide (LPS), peptidoglycan (PGN), and glucan (GLU), as determined by ELISA. …”
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Polystyrene nanoparticles induce DNA damage and apoptosis in HeLa cells by Antonia Feola, Manoj Madheswaran, Grazia Romano, Awet Ghebretinsae Tewelde, Eunice Wairimu Maina, Gianluca D'Abrosca, Maria della Valle, Mariacristina Cocca, Maria Emanuela Errico, Carla Isernia, Roberto Fattorusso, MariaTeresa Gentile, Gaetano Malgieri

“…The genotoxic potential is further highlighted by the presence of low molecular weight DNA fragments in PS-NPs treated cells, and by the relationship between polystyrene nanoplastics and γ-H2AX. …”
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Systematic identification of pathological mechanisms, prognostic biomarkers and therapeutic targets by integrating lncRNA expression variation in salivary gland mucoepidermoid carc... by Yan-ping Zou, Xiao-feng Shan, Jia-xuan Qiu, Yan Geng, Shang Xie, Ruo-lan Xiang, Zhi-gang Cai

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The Platelet-Specific Gene Signature in the Immunoglobulin G4-Related Disease Transcriptome by Ali Kemal Oguz, Cagdas Sahap Oygur, Bala Gur Dedeoglu, Irem Dogan Turacli, Sibel Serin Kilicoglu, Ihsan Ergun

“…<i>Results</i>: When IgG4-RD patients were compared with controls, 268 DEGs (204 with increased and 64 with decreased expression) were detected. Among these, a molecular signature of 22 platelet-specific genes harbored genes important for leukocyte–platelet aggregate formation (i.e., <i>CLEC1B</i>, <i>GP1BA</i>, <i>ITGA2B</i>, <i>ITGB3</i>, <i>SELP</i>, and <i>TREML1</i>) and extracellular matrix synthesis (i.e., <i>CLU</i>, <i>PF4</i>, <i>PPBP</i>, <i>SPARC</i>, and <i>THBS1</i>). …”
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Median Preoptic Nucleus Mediates the Cardiovascular Recovery Induced by Hypertonic Saline in Hemorrhagic Shock by Nathalia Oda Amaral, Lara Marques Naves, Marcos Luiz Ferreira-Neto, André Henrique Freiria-Oliveira, Eduardo Colombari, Daniel Alves Rosa, Angela Adamski da Silva Reis, Danielle Ianzer, Carlos Henrique Xavier, Gustavo Rodrigues Pedrino

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Comparison of efficacy and safety of thrombus prevention strategies after abdominal and pelvic cancer surgery: Bayesian network based meta-analysis by Shiran Qin, Shiran Qin, Sitong Guo, Yucheng Yao, Yucheng Yao, Ying He, Dandan Xu, Dandan Xu, Henghai Su, Xiaoyu Chen, Haoru Meng

“…The DMA results showed that low molecular weight heparin (LMWH) was more effective in preventing VTE compared to no treatment (OR = 1.96; 95% CI: 1.21 to 3.19), and LMWH plus physiotherapy was more effective than LMWH (OR = 10.95; 95% CI: 1.33 to 90.40). …”
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Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice by Yan Yang, Wenting Zhang, Xiaohui Wu, Jing Wu, Chengjun Sun, Feihong Luo, Zhou Pei

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