AI-optimized electrochemical aptasensors for stable, reproducible detection of neurodegenerative diseases, cancer, and coronavirus by Amira Elsir Tayfour Ahmed, Th.S. Dhahi, Tahani A. Attia, Fawzia Awad Elhassan Ali, Mohamed Elshaikh Elobaid, Tijjani Adam, Subash C.B. Gopinath

“…Leveraging data-driven AI techniques, these sensors provide a non-invasive, cost-effective alternative to traditional methods, with applications in detecting molecular biomarkers for neurodegenerative diseases, cancer, and coronavirus. …”
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Mapping genomic regions for reproductive stage drought tolerance in rice from exotic landrace-derived population by Challa Venkateshwarlu, Challa Venkateshwarlu, Paresh Chandra Kole, Arun Kumar Singh, Pronob J. Paul, Pallavi Sinha, Vikas Kumar Singh, Arvind Kumar

“…Thus, recent breeding efforts have aimed to integrate drought tolerance traits in existing rice varieties through conventional and molecular approaches. The identification of grain yields quantitative trait loci (QTLs) under drought conditions, an important trait with high selection efficiency, may lead to the development of drought-tolerant rice varieties. …”
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Mechanism of Mongolian Medicine Batri-7 on Salmonella Enteritis by Yang D, Chen S, Borijihan H, Aoqier A, Sarula S, Siqin S, Manda M, Temuqile T, Baigude H

“…BT-7 contains plant-derived bioactive compounds, but its molecular mechanism of action remains unclear. This study explores BT-7’s antibacterial compounds and therapeutic mechanism in a Salmonella enteritis mouse model.Methods: The active components of BT-7 were detected by liquid chromatography-tandem mass spectrometry assay and identified by UPLC/Q-TOF-MS. …”
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Budget Impact of Rivaroxaban for the Prevention of Thromboembolic Events after Hip or Knee Replacement in Spain by Xavier Granero Xiberta, Antonio Murcia, José Ricardo Troncoso Durán, Claudio Gómez Zubeldia, Aleix Llorac Moix, Ruth Graefenhain De Codes, Maria Giovana Ferrario, Luis Lizán

“…In Spain, pharmacological prophylaxis is performed with low-molecular-weight heparin, enoxaparin being the most commonly used. …”
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Epidermal stem cell derived exosomes-induced dedifferentiation of myofibroblasts inhibits scarring via the miR-203a-3p/PIK3CA axis by Shixin Zhao, Haoran Kong, Dahu Qi, Yushuang Qiao, Yu Li, Zhiming Cao, Hanwen Wang, Xuefeng He, Hengdeng Liu, Hao Yang, Suyue Gao, Tao Liu, Julin Xie

“…Transcriptomic sequencing and rescue experiments were used to investigate the molecular mechanism by which miR-203a-3p in EpiSC-EVs induces myofibroblast dedifferentiation. …”
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Insights into the relations between cell wall integrity and in vitro digestion properties of granular starches in pulse cotyledon cells after dry heat treatment by Ping Li, Bin Zhang, Rui Liu, Li Ding, Xiong Fu, Haiteng Li, Qiang Huang, Xiaowei He

“…The morphological features suggested that all cell samples do not exhibit remarkable changes after being subjected to DHT. Molecular rearrangement and the crystallite disruption of starch granules entrapped in cells occurred during DHT as assessed by the crystal structure and thermal properties. …”
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Breastfeeding and Neonatal Age Influence Neutrophil-Driven Ontogeny of Blood Cell Populations in the First Week of Human Life by Sebastiano Montante, Rym Ben-Othman, Nelly Amenyogbe, Asimenia Angelidou, Anita van den Biggelaar, Bing Cai, Yixuan Chen, Alansana Darboe, Joann Diray-Arce, Rebecca Ford, Olubukola Idoko, Amy Lee, Mandy Lo, Kerry McEnaney, Mehrnoush Malek, David Martino, Geraldine Masiria, Oludare A. Odumade, William Pomat, Casey Shannon, Kinga Smolen, The EPIC Consortium, Al Ozonoff, Peter Richmond, Scott Tebbutt, Ofer Levy, Beate Kampmann, Ryan Brinkman, Tobias Kollmann

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An exploratory analysis of differences in serum protein expression by sex in patients with systemic sclerosis associated interstitial lung disease by Giuliana Cerro-Chiang, Matthew Ayres, Alejandro Rivas, Sarah J. Parker, Mitra Mastali, Peter Chen, Jennifer E. Van Eyk, Paul J. Wolters, Francesco Boin, Tanzira Zaman

“…These proteins could influence disease progression and treatment response and underscore the importance of personalized therapeutic strategies and further research into sex-related molecular pathways in SSc-ILD. Clinical trial number Not applicable.…”
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Infection-Related Stillbirths: A Detailed Examination of a Nine-Year Multidisciplinary Study by Liliana Gabrielli, Matteo Pavoni, Francesca Monari, Federico Baiesi Pillastrini, Maria Paola Bonasoni, Chiara Locatelli, Maria Bisulli, Alessandra Vancini, Ilaria Cataneo, Margherita Ortalli, Giulia Piccirilli, Alessia Cantiani, Simone Ambretti, Fabio Facchinetti, Tiziana Lazzarotto

“…Methods: Between 2014 and 2022, microbiological investigations on maternal, placental and fetal samples of SB cases were performed according to a standardized protocol including serology, cultures, and molecular biology. Autopsies and placental examination were mandatory in all SB cases. …”
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Tissue Doppler echocardiography predicts long-term cardiovascular mortality: the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) legacy 20-year follow-up study by Simon Thom, Alice Stanton, Jamil Mayet, Amit Kaura, Darrel Francis, Anoop SV Shah, Andrew Sharp, Alun D Hughes, Neil R Poulter, Anenta Ratneswaren, Tong Wu, Somayeh Rostamian, Devan Wasan, PS Sever

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Evaluation of Arbuscular Mycorrhizal Fungi Capacity to Alleviate Abiotic Stress of Olive (Olea europaea L.) Plants at Different Transplant Conditions by María Josefina Bompadre, Mariana Pérgola, Laura Fernández Bidondo, Roxana Paula Colombo, Vanesa Analía Silvani, Alejandro Guillermo Pardo, Juan Antonio Ocampo, Alicia Margarita Godeas

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The StbHLH47 transcription factor negatively regulates drought tolerance in potato (Solanum tuberosum L.) by Peijie Wang, Xiaojuan Wu, Nan Li, Hushuai Nie, Yu Ma, Juan Wu, Zhicheng Zhang, Yanhong Ma

“…In summary, our results indicate that StbHLH47 is a negative regulator of drought tolerance and provide a theoretical basis for further studies on the molecular mechanism involved.…”
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Follistatin-Like 1: A Potential Mediator of Inflammation in Obesity by Nengguang Fan, Haiyan Sun, Yufan Wang, Yifei Wang, Lijuan Zhang, Zhenhua Xia, Liang Peng, Yanqiang Hou, Weiqin Shen, Rui Liu, Jiajing Yin, Yongde Peng

“…Obesity is associated with a state of chronic low-grade inflammation, which contributes to insulin resistance and type 2 diabetes. However, the molecular mechanisms that link obesity to inflammation are not fully understood. …”
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Bringing lab to the field: Exploring innovations in point-of-care diagnostics for the rapid detection and management of tropical diseases in resource-limited settings by Abdullahi Tunde Aborode, Ridwan Olamilekan Adesola, Godfred Yawson Scott, Emele Arthur-Hayford, Oche Joseph Otorkpa, Somuah Daniel Kwaku, Emmanuel Ebuka Elebesunu, Eghaghe Osadebamwen Nibokun, Ibude Jane Aruorivwooghene, Adetolase A. Bakre, Oluwaseun Adeolu Ogundijo, Olamilekan Gabriel Banwo, Oluwatobiloba Ige, Ibrahim O. Adelakun, Isreal Ayobami Onifade, Segun E. Ogungbemi, Boluwatife T. Dosunmu, Oluwaseunayo Deborah Ayando, Nike Idowu, Grace A. Adegoye, Olusegun Oluwaseun Jimoh

“…The review focuses on rapid diagnostic tests, molecular diagnostic tools, and smartphone-based applications, analyzing their advantages, limitations, and potential impact on healthcare delivery. …”
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Exosomal miR-222-3p derived from dermal papilla cells inhibits melanogenesis in melanocytes by targeting SOX10 in rabbits by Yang Chen, Tingting Lu, Yingying Dai, Yu Xue, Bohao Zhao, Xinsheng Wu

“…However, the specific role and underlying molecular mechanisms of exosomal miR-222-3p in melanogenesis remain elusive. …”
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Microbial assisted alleviation of nickel toxicity in plants: A review by Xinyu Mao, Bilal Ahmad, Sabir Hussain, Farrukh Azeem, Muhammad Waseem, Yousef Alhaj Hamoud, Hiba Shaghaleh, Amany H.A. Abeed, Muhammad Rizwan, Jean Wan Hong Yong

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Vaccine Prophylaxis of Pneumococcal Infections in Children under Conditions of Severe Flood in the Amur River Basin by Aleksandr G. Chuchalin, Gennadiy G. Onishchenko, Victor P. Kolosov, Olga P. Kurganova, Tatiana A. Zaitseva, Leonid G. Manakov, Galina N. Kholodok, Juliy M. Perelman, Roman S. Kozlov, Natalia M. Ivakhnishina, Olga E. Trotsenko, Albina P. Bondarenko

“…To study the circulation of serovariants of pneumococcus in inflammatory diseases of the respiratory tract and nasopharyngeal carrier, bacteriological and molecular genetic methods (RT-PCR in the mode of multiprime detection) were used. …”
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Immune regulatory genes impact the hot/cold tumor microenvironment, affecting cancer treatment and patient outcomes by Mengmeng Sang, Jia Ge, Juan Ge, Juan Ge, Gu Tang, Qiwen Wang, Jiarun Wu, Liming Mao, Liming Mao, Xiaoling Ding, Xiaorong Zhou

“…Furthermore, drug sensitivity and molecular docking analyses were performed to identify potential drug candidates capable of transforming cold tumors into hot tumors. …”
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Screening Wild Birds for Tick-Borne Zoonotic Pathogens in Portugal by Filipa Loureiro, João R. Mesquita, Luís Cardoso, Sérgio Santos-Silva, Guilherme Moreira, Jaqueline T. Bento, Vanessa Soeiro, Andreia Gonçalves, Filipe Silva, Patrícia F. Barradas, Ana C. Matos, Manuela Matos, Ana Cláudia Coelho

“…In the One Health context, it is relevant to understand how faraway avian populations play a role in the epidemiology of infectious diseases. Further molecular studies are needed to deepen the knowledge of avian piroplasmosis, borreliosis and hepatozoonosis.…”
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Mouse strain-specific responses along the gut-brain axis upon fecal microbiota transplantation from children with autism by Naika Prince, Lucia N. Peralta Marzal, Léa Roussin, Magali Monnoye, Catherine Philippe, Elise Maximin, Sabbir Ahmed, Karoliina Salenius, Jake Lin, Reija Autio, Youri Adolfs, R. Jeroen Pasterkamp, Johan Garssen, Laurent Naudon, Sylvie Rabot, Aletta D. Kraneveld, Paula Perez-Pardo

“…Several factors are linked to the pathophysiology of autism spectrum disorders (ASD); however, the molecular mechanisms of the condition remain unknown. …”
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