Using the synthetic form RS5 to obtain new introgressive lines of common wheat by R. O. Davoyan, I. V. Bebyakina, E. R. Davoyan, Y. S. Zubanova, D. M. Boldakov, D. S. Mikov, V. A. Bibishev, A. N. Zinchenko, E. D. Badaeva

“…Substitutions 4D(4Dt ), 6D(6Dt ) from Ae. tauschii and 7D(7S) from Ae. speltoides were obtained for the first time. Molecular analysis of 12 lines did not reveal effective leaf rust resistance genes, presumably present in synthetic forms of M.it.…”
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MADS-box encoding gene Tunicate1 positively controls maize yield by increasing leaf number above the ear by Yan Li, Jian Wang, Shuyang Zhong, Qiang Huo, Qun Wang, Yunlu Shi, Hangqin Liu, Jiacheng Liu, Yang Song, Xiaojian Fang, Zhongwei Lin

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Toward measurements of absolute membrane potential in Bacillus subtilis using fluorescence lifetime by Debjit Roy, Xavier Michalet, Evan W. Miller, Kiran Bharadwaj, Shimon Weiss

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A comparison of new and existing rootstocks to reduce canker of apple trees caused by Neonectria ditissima (Nectriaceae, Hypocreales) by Lucas A. Shuttleworth, Sonia Newman, Ioannis Korkos

“…An interplay of factors are likely involved in the development of canker including location and environmental effects—rainfall, relative humidity, temperature, wind, soil type, topography, aspect, and other seasonal infection processes including pathogen inoculum load, and rainsplash of inoculum between trees and within individual trees, the genetics and physiology of each scion/rootstock combination, water and nutritional status of trees, hormonal and molecular signalling, and orchard management including pruning and removal of cankers.…”
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Chicken C4BPM facilitates replication of H5N1 and H9N2 Avian Influenza Viruses by inhibiting the production of type I interferons by Huizi Li, Shishi Wang, Ruihong Guo, Xijiao Chen, Yuanyuan Huang, Weixin Jia, Zhangyong Ning

“…To verify the role of C4BPM in replication of AIVs, C4BPM knockout (C4BPM-KO) and stable overexpressing (C4BPM-overexpressing) DF-1 cells were generated using lentivirus-mediated CRISPR/Cas9 gene editing technology and molecular cloning strategies. Replication of H5N1 and H9N2 AIVs were promoted in C4BPM-overexpressing DF-1 cells with inhibited expression of type I IFNs (IFN-α, IFN-β), protein kinase R (PKR), cholesterol 25-hydroxylase (CH25H), interferon regulatory factor (IRF) 3, and mitochondrial antiviral signaling protein (MAVS) compared to that of the DF-1 cells. …”
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Marker-assisted selection in the development of advanced apple-tree forms and donors combining scab resistance with increased fruit storability by I. I. Suprun, E. A. Egorov, A. I. Nasonov, E. V. Lobodina, S. V. Tokmakov, I. V. Stepanov

“…The results of the phenotypic resistance assessment confirmed the correspondence of the resistant phenotype / dominant allele of the gene for most plants. Molecular genetics analysis of the Md-ACS1 gene disclosed its allelic combinations. …”
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Spatial Distribution of Tsetse Flies and Trypanosome Infection Status in a Vector Genetic Transition Zone in Northern Uganda by Robert Opiro, Okello Allele Moses, Robert Opoke, Francis A. Oloya, Esther Nakafu, Teresa Iwiru, Richard Echodu, Geoffrey M. Malinga, Joel L. Bargul, Elizabeth A. Opiyo

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Primary Neuroendocrine Carcinoma of Ocular Adnexa by Daisuke Yamanouchi, Toshiyuki Oshitari, Yosuke Nakamura, Jiro Yotsukura, Kaoru Asanagi, Takayuki Baba, Tomohiro Nizawa, Takashi Kishimoto, Yoko Yonemori, Satoshi Ota, Shuichi Yamamoto

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Effects of exogenous SLs on growth and physiological characteristics of flue-cured tobacco seedlings under different degrees of drought stress by Xiao-dong Wang, Yi-nan Zhang, Xiao-guo Wang, Ye Zhuang, Shao-hua Ge

“…However, the interactions between strigolactones and various hormones under drought stress require further investigation to elucidate the underlying molecular mechanisms. The application methods of strigolactones should be optimized.…”
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Exosomes derived from hUC-MSCs exhibit ameliorative efficacy upon previous cesarean scar defect via orchestrating β-TrCP/CHK1 axis by Xiaoling Zeng, Yuan Liao, Dan Huang, Jing Yang, Zhihua Dai, Zhengyong Chen, Xin Luo, Han Gong, Shengwen Huang, Leisheng Zhang

“…Meanwhile, the ex vivo scratch wound healing model is used for exploring the underlying molecular mechanism. On the one hand, we took advantage of the TGF-β-induced in vitro myofibrotic model and the full-thickness uterine injury rat model to verify the efficacy of human umbilical cord MSC-derived exosomes (hUC-MSC-Exos). …”
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Gas Chromatography Coupled to High Resolution Time-of-Flight Mass Spectrometry as a High-Throughput Tool for Characterizing Geochemical Biomarkers in Sediments by Hector Henrique Ferreira Koolen, Clécio Fernando Klitzke, Joe Binkley, Jeffrey Patrick, Ana Cecília Rizatti de Albergaria-Barbosa, Rolf Roland Weber, Márcia Caruso Bícego, Marcos Nogueira Eberlin, Giovana Anceski Bataglion

“…Polycyclic aromatic hydrocarbons were also identified in the samples by their molecular ions. The characterization of geochemical biomarkers along a sedimentary core collected in the area of Valo Grande Channel (Cananéia-Iguape Estuarine-Lagunar System (São Paulo, Brazil)) provided evidences of environmental changes. …”
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Preclinical evaluation of the potential PARP-imaging probe [carbonyl-11C]DPQ by Katarína Benčurová, Theresa Balber, Victoria Weissenböck, Lukas Kogler, Joachim Friske, Verena Pichler, Markus Mitterhauser, Marcus Hacker, Cécile Philippe, Marius Ozenil

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Different expression of circulating microRNA profile in tibetan OSAHS with metabolic syndrome patients by Xue-feng Shi, Xiang He, Ze-rui Sun, Jie Duo, Hao Yang

“…This study identifies distinctive miRNA signatures in OSAHS with Metabolic Syndrome (Mets) patients from healthy subjects, that could serve as diagnostic biomarkers or describe differential molecular mechanisms with potential therapeutic implications. …”
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Exploring the anti-metastatic potential of sunitinib and novel analogs in colorectal cancer: insights into HIF-1α mediated metastasis by Fatemeh B. Rassouli, Maryam M. Matin, Maryam M. Matin, Farzin Hadizadeh, Farzin Hadizadeh, Masoud Nejabat, Hossein Allahverdizadeh, Hamidreza Jamali, Shahin Gharedaghi, Halimeh Hassanzadeh

“…For in vitro studies, analogs of sunitinib were synthesized, and cells were assessed for viability, migration, invasion, MMPs activity and gene expression in hypoxic condition.Results and DiscussionComputational analyses highlighted the importance of HIF-1α as a crucial mediator of metastasis in CRC. Molecular docking and dynamics simulations demonstrated favorable and stable interaction of sunitinib and three novel analogs with HIF-1α PAS-B domain. …”
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The relationship between gallstone disease and the genetic variants of the sterol transporter adenosine triphosphate–binding cassette G8 and G5 in Egyptians by Menna A. Hassan, Salwa M. Abo El-Khair, Noha M. Mesbah, Dina M. Abo-Elmatty, Asmaa R. Abdel-Hamed

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Healthcare resource use of patients with transthyretin amyloid cardiomyopathy by Rosa Lauppe, Johan Liseth Hansen, Anna Fornwall, Katarina Johansson, Mark H. Rozenbaum, Anne Mette Strand, Merja Vakevainen, Johanna Kuusisto, Einar Gude, J. Gustav Smith, Finn Gustafsson

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Comparative Genomic In Situ Hybridization and the Possible Role of Retroelements in the Karyotypic Evolution of Three Akodontini Species by Naiara Pereira Araújo, Gustavo Campos Silva Kuhn, Flávia Nunes Vieira, Thaís Queiroz Morcatty, Adriano Pereira Paglia, Marta Svartman

“…Among them, the genus Akodon has been extensively analyzed with classical and molecular cytogenetics, which allowed the identification of a large number of intra- and interspecific chromosomal variation due to Robertsonian rearrangements, pericentric inversions, and heterochromatin additions/deletions. …”
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Oncolytic Viruses and Immunotherapy for the Treatment of Uveal Melanoma and Retinoblastoma: The Current Landscape and Novel Advances by Merve Kulbay, Nicolas Tuli, Massimo Mazza, Armaan Jaffer, Sarinee Juntipwong, Emily Marcotte, Stuti Misty Tanya, Anne Xuan-Lan Nguyen, Miguel N. Burnier, Hakan Demirci

“…This manuscript provides an in-depth review of the molecular design of oncolytic viruses (e.g., virus capsid proteins and encapsulation technologies, vectors for delivery, cell targeting) and immunotherapy. …”
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Studying sex differences in responses to fibroblast growth factor 21 administration in obese mice consuming a sweet-fat diet by N. М. Bazhan, T. V. Jakovleva, A. Yu. Kazantseva, N. E. Kostina, P. E. Orlov, N. Yu. Balybina, K. О. Baranov, E. N. Makarova

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Seven Immune-Related Genes’ Prognostic Value and Correlation with Treatment Outcome in Head and Neck Squamous Cell Carcinoma by Rui Mu, Yuehong Shen, Chuanbin Guo, Xinyun Zhang, Hongyu Yang, Huijun Yang

“…The protein-protein interaction (PPI) network and functional enrichment pathway investigations were utilized to explore possible potential molecular mechanisms. Finally, the hub gene’s differential mRNA expression levels were evaluated by means of the Gene Expression Profiling Interactive Analysis (GEPIA), and the Human Protein Atlas (HPA) was utilized for the validation of their translational levels. …”
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