DRomics, a workflow to exploit dose-response omics data in ecotoxicology by Delignette-Muller, Marie Laure, Siberchicot, Aurélie, Larras, Floriane, Billoir, Elise

“…Coupled to dose-response experimental designs, they allow a non-targeted assessment of organism responses at the molecular level along an exposure gradient. However, describing the dose-response relationships on such high-throughput data is no easy task. …”
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Latin America’s Dengue Outbreak Poses a Global Health Threat by Michelle Teixeira de Almeida, Davi Gabriel Salustiano Merighi, Aline Biazola Visnardi, Cauê Augusto Boneto Gonçalves, Vitor Martins de Freitas Amorim, Anielle Salviano de Almeida Ferrari, Anacleto Silva de Souza, Cristiane Rodrigues Guzzo

“…It also evaluates diagnostic strategies combining clinical assessment with serological and molecular testing, providing information to improve diagnostic and preventive measures. …”
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Enhance Oil Recovery in Fracture-Cave Carbonate Reservoirs Using Zwitterion-Anionic Composite Surfactant System by Wei Peng, Qing You, Xiaoqiang Liu, Bojie Zhou, Xingxing Ding, Yuechun Du, Liangfei Xiao

“…Surfactant flooding is usually adopted in these conditions because it can mitigate water channeling and enhance sweep efficiency by lowering the interfacial tension (it refers to the force that is generated due to the unbalanced molecular attraction on the liquid surface layer and causes the liquid surface to contract) between oil and water. …”
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Evaluation of Fructooligosaccharides and Inulins as Potentially Health Benefiting Food Ingredients by HPAEC-PED and MALDI-TOF MS by Chiara Borromei, Maria Careri, Antonella Cavazza, Claudio Corradini, Lisa Elviri, Alessandro Mangia, Cristiana Merusi

“…To characterize FOS and inulin at different degrees of polymerization and to assure correct molecular assignment, MALDI-TOF MS analysis was also investigated. …”
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Food-derived peptides with inhibitory capacity for HMG-CoA reductase activity: a potential nutraceutical for hypercholesterolemia by Guillermo Santos-Sánchez, Ana Isabel Álvarez-López, Eduardo Ponce-España, Patricia Judith Lardone, Antonio Carrillo-Vico, Ivan Cruz-Chamorro

“…The analysis of the action mechanism and physicochemical characteristics of the HMG-CoAR inhibitory peptides revealed that the molecular weight, amino acid composition, charge, and polarity are key aspects of the interaction with the HMG-CoAR enzyme. …”
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Deletion of cyclin dependent kinase inhibitor 2a gene as a marker of oropharyngeal carcinomas non-associated with human papillomavirus and its prognostic value by I.S. Shponka, Bondarenko O.O. Bondarenko ч, O.V. Kovtunenko, V.V. Rakhmanov

“…However, prognostic evaluation for non-papillomavirus-associated oropharyngeal squamous cell carcinoma remains a problem that could be solved through the molecular mechanisms of squamous cell carcinoma for the purpose of further development of target therapies. …”
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Search of Reflectance Indices for Estimating Photosynthetic Activity of Wheat Plants Under Drought Stress by Firuz Abdullaev, Daria Churikova, Polina Pirogova, Maxim Lysov, Vladimir Vodeneev, Oksana Sherstneva

“…The indices NDI_572/545 and NDI_820/630 showed the best combination of sensitivity to soil moisture deficit and strong relationship with photosynthetic activity under drought stress. Possible molecular and physiological causes of this relationship are discussed. …”
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Taming of trinitromethyl-oxadiazole to access high density and high oxygen balance via a dual modulation strategy by Jinya Zhang, Teng Fei, Jingwei Meng, Jinxiong Cai, Lei Zhang, Siping Pang, Chunlin He

“…In this work, an effective dual modulation strategy involving both molecular isomerization and crystal morphology control was employed to design and optimize trinitromethyl-oxadiazole with improved comprehensive performance. …”
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Characterizing PM2.5 Secondary Aerosols via a Fusion Strategy of Two-stage Positive Matrix Factorization and Robust Regression by Chun-Sheng Huang, Ho-Tang Liao, Chia-Yang Chen, Li-Hao Young, Ta-Chih Hsiao, Tsung-I Chou, Jyun-Min Chang, Kuan-Lin Lai, Chang-Fu Wu

“…Additionally, organic molecular tracers were incorporated into PMF for source identification. …”
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The p85 Regulatory Subunit of PI3K Mediates cAMP-PKA and Insulin Biological Effects on MCF-7 Cell Growth and Motility by E. Di Zazzo, A. Feola, C. Zuchegna, A. Romano, C. F. Donini, S. Bartollino, C. Costagliola, R. Frunzio, P. Laccetti, M. Di Domenico, A. Porcellini

“…It has been identified as a serine (S83) in the p85αPI3K that is phosphorylated by protein kinase A (PKA). To determine the molecular mechanism linking PKA to insulin-mediated PI3K activation, we used p85αPI3K mutated forms to prevent phosphorylation (p85A) or to mimic the phosphorylated residue (p85D). …”
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Filtration assisted pretreatment for rapid enrichment and accurate detection of Salmonella in vegetables by Bin Li, Hanling Wang, Jianguo Xu, Wei Qu, Li Yao, Bangben Yao, Chao Yan, Wei Chen

“…In this research, we proposed a new strategy of isothermal-molecular-amplification integrated with lateral-flow-strip for rapid detection of Salmonella without traditional enrichment-culture. …”
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Exploring the immunohistochemical profile of basosquamous carcinoma and its clinicopathological associations by Cemile Tuğba Altunel, Gonca Özgün, Arzu Karataş, Özlem Özen, Deniz Seçkin, Tülin Güleç, Deren Özcan

“…Background and Design: Basosquamous carcinoma (BSC) is widely accepted as a basal cell carcinoma variant. Despite an unknown molecular pathogenesis, specific mutations are associated with its squamatization. …”
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A deep contrastive learning-based image retrieval system for automatic detection of infectious cattle diseases by Veerayuth Kittichai, Morakot Kaewthamasorn, Apinya Arnuphaprasert, Rangsan Jomtarak, Kaung Myat Naing, Teerawat Tongloy, Santhad Chuwongin, Siridech Boonsang

“…The findings may aid in the early diagnosis of anaplasmosis infections in remote areas without access to veterinary care or costly molecular diagnostic tools.…”
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DNA-encoded dynamic hydrogels for 3D bioprinted cartilage organoids by Ziyu Chen, Hao Zhang, Jingtao Huang, Weizong Weng, Zhen Geng, Mengmeng Li, Jiacan Su

“…DNA, with its ability to be intricately encoded and reversibly cross-linked into hydrogels, offers precise manipulation at both molecular and spatial structural levels. This endows the hydrogels with viscoelasticity, printability, cell recognition, and stimuli responsiveness. …”
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Optimization of UAE-NADES green extraction of bioactive compounds from chickpea (Cicer arietinum L.) sprouts using simplex lattice mixture design methodology by Waseem Khalid, Hyrije Koraqi, Imed E Benmebarek, Andrés Moreno, Tawfiq Alsulami, Robert Mugabi, Gulzar Ahmad Nayik

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DLAT is involved in ovarian cancer progression by modulating lipid metabolism through the JAK2/STAT5A/SREBP1 signaling pathway by Hui Wang, Shen Luo, Yue Yin, Yang Liu, Xiaomei Sun, Ling Qiu, Xin Wu

“…Accumulated evidence highlights the pivotal role of reprogrammed lipid metabolism in fueling OC progression, however, the intricate underlying molecular mechanisms are not fully elucidated. Methods DLAT expression was assessed in OC tissues and cell lines by immunohistochemistry, western blot and qRT-PCR analysis. …”
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The influence of COVID-19 pandemic on secondary prevention in non-COVID patients with cardioembolic stroke by Lučić-Prokin Aleksandra L., Bogdanović Milan M., Pustahija Tatjana L., Stamenković Marija S.

“…The most common therapeutic recommendations for secondary prevention of CS with NVAF included apixaban (p=0.0336) and bridging therapy: low-molecular weight heparin with acetylsalicylic acid (LMWH+ASA) (p=0.0011), both during the COVID-19 period. …”
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Long-term risk factors for developing Barrett’s oesophagus in patients with gastro-oesophageal reflux disease: a longitudinal cohort study by John F Dillon, Paul Brennan, James Cotton, James Carberry, Christopher J Byrne

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Structure characterization of Grifola frondosa polysaccharide and its effect on insulin resistance in HFD-fed mice by Yin-Yi Ding, Jinchi Lan, Yuxin Wang, Yuxiang Pan, Tianyuan Song, Shizhu Liu, Zhenyu Gu, Yujun Ge

“…GPF-F2 was further separated into two fractions, namely GFP-N1 and GFP-N2. The molecular weight of GFP-N1 and GFP-N2 was 3.323×103 kDa and 10.8 kDa, respectively. …”
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Nanopore Confinement Effect on the Phase Behavior of CO2/Hydrocarbons in Tight Oil Reservoirs considering Capillary Pressure, Fluid-Wall Interaction, and Molecule Adsorption by Zhixue Zheng, Yuan Di, Yu-Shu Wu

“…Finally, the recovery mechanisms for CO2 injection are investigated in terms of minimum miscibility pressure (MMP), solution gas-oil ratio, oil volume expansion, viscosity reduction, extraction of lighter hydrocarbons, and molecular diffusion. Results indicate that nanopore confinement effect contributes to decrease MMP, which suppresses to 650 psi (65.9% smaller) as the pore size decreases to 2 nm, resulting in the suppression of the resistance of fluid transport. …”
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