Functional analysis of heterozygous variants in the SALL1 gene in 2 children with Townes-Brocks syndrome with FSGS by Rong Liang, Bixia Zheng, Chunli Wang, Sanlong Zhao, Wei Zhou, Ying Chen, Ruochen Che

“…Experimental validation demonstrated that both variants led to alterations in the molecular size, expression level, and localization of the Sall1 protein, suggesting that these SALL1 gene variants might contribute to FSGS by impacting podocyte function.…”
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Effects of Soil-Transmitted Helminths and Intestinal Protozoan Infections on Haemoglobin Levels among School-Aged Children in Belo and Bui, North West Cameroon: A Cross-Sectional S... by Frederick Nchang Cho, Humphrey Ngala Ngala, Ranibell Tung Bongazi, Rogers Sanga Kinsam, Beltha Tahnteng Tata, Desmond Aji, Paulette Ngum Fru, Patrick Kofon Jokwi

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Evaluation and diagnostic approach in patient with Perrault Syndrome by Rachael Christin Nathania, Steven Yulius Usman, Ekarini Aryasatiani

“…Conclusion: Perrault Syndrome, a rare hereditary condition, manifests as sensorineural hearing loss (SNHL) and ovarian dysfunction, including primary ovarian insufficiency (POI) and gonadal dysgenesis, in individuals with a 46, XX karyotype. Molecular diagnosis remains challenging. Consultation with a pediatric endocrinologist can guide cyclic estrogen and progesterone therapy to induce withdrawal bleeding in adolescents with amenorrhea. …”
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Emergence of Enteric Viruses in Production Chickens Is a Concern for Avian Health by Elena Mettifogo, Luis F. N. Nuñez, Jorge L. Chacón, Silvana H. Santander Parra, Claudete S. Astolfi-Ferreira, José A. Jerez, Richard C. Jones, Antonio J. Piantino Ferreira

“…Several viruses have been identified in recent years in the intestinal contents of chickens and turkeys with enteric problems, which have been observed in commercial farms worldwide, including Brazil. Molecular detection of these viruses in Brazil can transform to a big threat for poultry production due to risk for intestinal integrity. …”
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Effect of afzelin on inflammation and lipogenesis in particulate matter-stimulated C. acnes-treated SZ95 sebocytes by Ji Yeon Hong, Yong Hee Choi, Yoon Jin Roh, Mi-Kyung Lee, Christos C. Zouboulis, Kui Young Park

“…However, its effects on the molecular aspects of inflammation and lipogenesis in SZ95 sebocytes has not been investigated.ObjectiveThis study aimed to (i) investigate inflammatory and sebum secretion changes when a Cutibacterium acnes-treated immortalized human sebocyte cell line (SZ95) is exposed to particulate matter (PM) and (ii) examine the effects of afzelin on these.MethodsTo investigate the effect of afzelin on PM- and C. acnes-treated SZ95 sebocytes, we injected heat-killed C. acnes into SZ95 cells to induce acne-like status. …”
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Thermal enhancement using variable characteristics and tripartite diffusion features of solar aircraft wings in context of Reiner-Philippoff hybrid nanofluid passing through a para... by Esraa N. Thabet, A.M. Abd-Alla, S.M.M. El-Kabeir

“…Heat source/sink phenomena, various slip boundary conditions, thermal radiative, chemical reaction, variable thermal conductivity, and variable molecular diffusivity are some of the special characteristics that are taken into account while assessing the heat transfer efficiency of airplane wings. …”
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Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: implications for the involvement of pirin by Bardees M. Foda, Bardees M. Foda, Annika E. Baker, Annika E. Baker, Annika E. Baker, Łukasz Joachimiak, Marzena Mazur, Richard R. Neubig, Richard R. Neubig, Richard R. Neubig

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RECK as a Potential Crucial Molecule for the Targeted Treatment of Sepsis by Qin Y, Liao S, Sun J, Ye H, Li J, Pan J, He J, Xia Z, Shao Y

“…Recently, RECK has been defined as the negative regulator of adisintegrin and metalloproteinases (ADAMs) and matrix metalloproteinases (MMPs), which are both membrane “molecular scissors” and aggravate the poor prognosis of sepsis. …”
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The role of 1-Deoxysphingolipids and Polyamines in the pathogenesis of placental syndrome by Filiz Yarsilikal Guleroglu, Ali Cetin, Goknil Pelin Coskun, Meltem Caliskan, Fulya Karaduman, Can Bilginer, Resat Misirlioglu, Sinem Tekin, Merve Nur Al, Tugce Caklili, Yusuf Tutar

“…While impaired placentation is central to their pathophysiology, the underlying molecular mechanisms remain incompletely understood. …”
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Novel Insights into the Nobilamide Family from a Deep-Sea <i>Bacillus</i>: Chemical Diversity, Biosynthesis and Antimicrobial Activity Towards Multidrug-Resistant Bacteria by Vincenza Casella, Gerardo Della Sala, Silvia Scarpato, Carmine Buonocore, Costanza Ragozzino, Pietro Tedesco, Daniela Coppola, Giovanni Andrea Vitale, Donatella de Pascale, Fortunato Palma Esposito

“…The integration of tandem mass spectrometry molecular networking and bioassay-guided fractionation unveiled this strain as a prolific factory of surfactins and nobilamides. …”
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Design of a new model yeast consortium for ecological studies of enological fermentation by Pourcelot, Eléonore, Vigna, Audrey, Marlin, Thérèse, Galeote, Virginie, Nidelet, Thibault

“…While extensive research has enhanced our understanding of S. cerevisiae, the development of multi-species fermentation starters has led to increased interest in yeast interactions and the role of microbial diversity in winemaking. Consequently, molecular methods have emerged to identify the different species at different stages of the winemaking process. …”
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HPV E6/E7, hTERT, and Ki67 mRNA RT-qPCR Assay for Detecting High-Grade Cervical Lesion with Microscope Slides by Geehyuk Kim, Jemberu Taye, Kwangmin Yu, Sunyoung Park, Jungho Kim, Sunghyun Kim, Dongsup Lee, Hye-young Wang, Kwang Hwa Park, Hyeyoung Lee

“…Since human papillomavirus (HPV) infection is known to be the predominant cause of cervical cancer, molecular HPV screening is currently used along with cytological and histological examination methods for precancer diagnosis. …”
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Assessing clenbuterol’s modulation of metabolic and inflammatory pathways in Nile tilapia (Oreochromas niloticous) fed high fat diet by Aya G. Rashwan, Doaa H. Assar, Abdallah S. Salah, Muyassar H. Abualreesh, Shimaa M. R. Salem, Norah Althobaiti, Zizy I. Elbialy

“…Abstract This study was performed to reveal the metabolic effects and molecular mechanisms that govern the dietary incorporation of clenbuterol on growth performance, haemato-biochemical changes, histological alteration, and gene expression regulating glucose and lipid metabolism in normal and high-fat diets fed in Nile tilapia (Oreochromis niloticus). …”
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Genes involved in DMSO-mediated yield increase of entomopathogenic nematodes by Xingxin Liu, Zhongchen Rao, Richou Han, Linhong Jin, Li Cao

“…These results demonstrate that DMSO regulates nematode gravidity by suppressing at least three selected genes, thereby enhancing IJ yield, providing molecular cues for understanding how DMSO regulates the EPN yield, and a new technology for enhancing nematode commercial production.…”
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Prevalence of <i>Batrachochytrium dendrobatidis</i> in Amphibians in Northwestern Italy’s Protected Areas by Arianna Meletiadis, Matteo Riccardo Di Nicola, Stefano Bovero, Marco Favelli, Marzia Pezzolato, Stefania Grella, Giusi Rezza, Pier Luigi Acutis

“…In the spring of 2023, Bd presence was detected in different amphibian species within two protected areas near Turin, Piedmont, Italy, following an unusual mortality event among the common toad (<i>Bufo bufo</i>). Histological and molecular analyses confirmed Bd infection in a deceased <i>Pelophylax</i> sp. specimen, prompting further investigation. …”
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TRIM26 exacerbates pathological cardiac hypertrophy by activating TAK1 by Xiaochuang Xia, Huajing Shan, Zhaoxia Jin, Tengfei Ma, Yemao Liu, Jianqing Zhang, Han Tian, Bizhen Dong, Chengsheng Xu, Shaoze Chen

“…In PE-treated NRCMs, Trim26 overexpression promoted cardiomyocyte enlargement and inflammation, while Trim26 knockdown had the opposite effects. RNA sequencing and molecular biology methodologies were performed to identify targets conducive to TRIM26 function. …”
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Health-related quality of life in children born preterm at school age: the mediating role of social support and maternal stress by Melissa Liher Martínez-Shaw, Melissa Liher Martínez-Shaw, Kari Anne I. Evensen, Kari Anne I. Evensen, Kari Anne I. Evensen, Sandra Melero, Sandra Melero, Yolanda Sánchez-Sandoval, Yolanda Sánchez-Sandoval

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CPSF6-RARγ interacts with histone deacetylase 3 to promote myeloid transformation in RARG-fusion acute myeloid leukemia by Tianhui Liu, Tanzhen Wang, Lijuan Qi, Yujie Liu, Meng Shan, Fuqiang Wang, Yanglan Fang, Sining Liu, Lijun Wen, Suning Chen, Depei Wu, Yang Xu

“…Hence, our data reveals the molecular bases of oncogenic CR fusion and provides a potential therapeutic approach against AML with CR fusion.…”
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Inferior Vena Cava Filter and Catheter-based Thrombolysis for Treatment of Massive Deep Vein Thrombosis: A Case Report by Sangram S Mangudkar, Sanket Genuji Shinde, Varun Bhaskar Lingneni, Satbir Kaur Malik, Sai Sirisha Nallani

“…A bilateral lower limb doppler ultrasound suggested thrombosis in the popliteal vein, great saphenous vein, deep femoral vein and common femoral vein in the left lower limb. Low molecular weight heparin injection was used to treat the patient. …”
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Effect of Fusion to the LTB Carrier Protein on Coronavirus Spike Protein Vaccine Candidates Produced in Maize by Erin Egelkrout, Magdalena Maj, Rodrigo Manjarin, Gina Fake, Muneaki Watanabe, Jenna Williams, Nate Blanchard, John Walker, Celine Hayden, John Howard

“…We found that the LTB fusion protein from both coronaviruses preferentially assembles into higher molecular weight multimers, consistent with the formation of trimers. …”
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