Investigation of Insulin-Like Growth Factor 2 mRNA Binding Protein 2 Gene Polymorphisms in Type 2 Diabetes Patients by Duygu Yolal Ertural, Ümit Çınkır, Nurcan Aras

“…DNA isolation was performed on peripheral blood samples from patients and healthy groups. The molecular analysis of rs1470579 and rs4402960 polymorphisms of IGF2BP2 gene of each individual was performed by using Real-Time PCR (Applied Biosystems) method. …”
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Comparative Study of Crucial Properties of Packaging Based on Polylactide and Selected Essential Oils by Ewa Olewnik-Kruszkowska, Astha Vishwakarma, Magdalena Wrona, Anis Bertella, Anna Rudawska, Magdalena Gierszewska, Beata Schmidt

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Preparation, structural property, and antioxidant activities of a novel pectin polysaccharide from the flowers of Hibiscus syriacus Linn. by Jialong Chen, Chaojun Ye, Lu Zhang, Zhiliang Xie, Jianjun Zhu, Zhi Zhang

“…Its chemical composition, monosaccharide profile, molecular weight distribution, and structural properties were elucidated through various analytical techniques.ResultsHFPS exhibited a predominant acidic monosaccharide composition, with galacturonic acid as the major constituent, indicating its pectin nature. …”
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Venous thromboembolic events: case history by T.V. Shelkovnikova, Kh.P. Takhchidi, G.V. Vavin, N.Yu. Shishlyannikova

“…More careful approach to treatment choice and prescription of prolonged anticoagulant therapy using direct inhibitors of Xa factor and low-molecular-weight heparin is required. Complex treatment for venous thromboembolism and  central retinal thrombosis (involving neuroprotective agents) should be applied.…”
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Snapshots of Pseudomonas aeruginosa SOS response reveal structural requisites for LexA autoproteolysis by Filippo Vascon, Sofia De Felice, Matteo Gasparotto, Stefan T. Huber, Claudio Catalano, Monica Chinellato, Riccardo Mezzetti, Alessandro Grinzato, Francesco Filippini, Lorenzo Maso, Arjen J. Jakobi, Laura Cendron

“…By integrating state-of-the-art structural approaches with in vitro binding and functional assays, we elucidated the molecular events activating the SOS response in P. aeruginosa, focusing on the RecA-LexA interaction. …”
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The steady-state level of plasma membrane ceramide is regulated by neutral sphingomyelinase 2 by Anne G. Ostermeyer-Fay, Abhay Kanodia, Ranjana Pathak, Maria Jose Hernandez-Corbacho, Aarnoud C. van der Spoel, Yusuf A. Hannun, Daniel Canals

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The Characteristic of Biofilm Formation in ESBL-Producing K. pneumoniae Isolates by Xiaofang Gao, Haili Wang, Zhijuan Wu, Pan Sun, Wei Yu, Donghua Chen, Yuhua Mao, Lili Fang, Jia Qian, Li Li, Qian Peng, Yanping Han

“…Thus, we next screened four ESBL-producing K. pneumoniae isolates (Kpn5, Kpn7, Kpn11, and Kpn16) with high homology and significant differences in biofilm formation using PFGE molecular typing, colony morphology, and crystal violet tests. …”
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胚胎干细胞分化为表皮样细胞的基因表达谱差异研究

“…基因本体（Gene Ontology，GO)分析显示与生物学过程（Biological Process,BP）相关的差异表达基因最多的是细胞过程（cellular process，CP），1931个；与亚细胞组分（Cellular Component, CC）相关的差基因中最多的是细胞和细胞组分（Cell, Cell part）相关基因，2391个；与分子功能（Molecular Function, MF）相关的差异基因中最多是的结合功能(binding)基因，1869个。…”
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Comparative assessment of the copy number of satellite repeats in the genome of Triticeae species by P. Yu. Kroupin, A. I. Yurkina, A. A. Kocheshkova, D. S. Ulyanov, G. I. Karlov, M. G. Divashuk

“…Our assessment of the copy number of new satellite repeats in the St-genome and the analysis of their amplification specificity between species can contribute to the molecular-genetic and chromosome markers used for evolutionary, phylogenetic, and population studies of Triticeae species.…”
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Differential effects of structurally different lysophosphatidylethanolamine species on proliferation and differentiation in pre-osteoblast MC3T3-E1 cells by Fumiaki Makiyama, Shiori Kawase, Aoi William Omi, Yusuke Tanikawa, Taishi Kotani, Teruki Shirayama, Naoyuki Nishimura, Taiga Kurihara, Naoto Saito, Jun Takahashi, Takeshi Uemura

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Upgrade of a variable temperature scanning tunneling microscope for nanometer-scale spectromicroscopy by B. Cirera, A. Sáez-Coronado, D. Arribas, J. Méndez, A. Sagwal, R. de Campos Ferreira, M. Švec, P. Merino

“…This upgrade opens new possibilities for studying surface chemistry, catalysis, and molecular electronics at state-of-the-art spatial and spectral resolutions using accessible SPM systems. • Portable lens holder • In-situ adjustable position • Nanometer-scale vibrational spectroscopy…”
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SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection by Richard C. Crist, Samar N. Chehimi, Saurabh S. Divakaran, Michael J. Montague, Sébastien Tremblay, Noah Snyder-Mackler, Martin O. Bohlen, Kenneth L. Chiou, Trish M. Zintel, Cayo Biobank Research Unit, Michael L. Platt, Halvor Juul, Guido Silvestri, Matthew R. Hayes, Dennis L. Kolson, Benjamin C. Reiner

“…In total, these results identify cell type-specific molecular mechanisms putatively capable of underlying long-term neurocognitive alterations in persons living with HIV.…”
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Genetic structure of the population of wild-growing vines of the Utrish Nature Reserve by E. T. Ilnitskaya, M. V. Makarkina, I. V. Gorbunov, I. V. Stepanov, T. D. Kozina, E. A. Kozhevnikov, V. K. Kotlyar

“…During the survey of the territory, 24 samples of wild grapes were found, which were described according to the main morphological characteristics and analyzed by the molecular genetic method. The found vines were genotyped using 15 DNA markers, including nine commonly used for DNA fingerprinting (VVS2, VVMD5, VVMD7, VVMD25, VVMD27, VVMD28, VVMD32, VrZAG62, VrZAG79) and VVIb23, which allows determining hermaphrodite and dioecious vines. …”
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Glioblastoma-derived migrasomes promote migration and invasion by releasing PAK4 and LAMA4 by Zhe Huang, Ming Wang, Yitian Chen, Hua Tang, Kuo Tang, Mingkuan Zhao, Wei Yang, Zhengjun Zhou, Junjie Tian, Wei Xiang, Shenjie Li, Qinglian Luo, Luotong Liu, Yanru Zhao, Tao Li, Jie Zhou, Ligang Chen

“…Overall, we identified migrasomes in GBM and the molecular mechanisms by which they regulate them, providing potential targets for treating GBM.…”
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Structural and functional analysis reveals the catalytic mechanism and substrate binding mode of the broad-spectrum endolysin Ply2741 by Shuang Wang, Xinxin Li, Jiahui Ma, Xiaochao Duan, Haiyan Wang, Linkang Wang, Dayue Hu, Wenwu Jiang, Xiangmin Li, Ping Qian

“…Furthermore, the key residues (R189 and W250) in the Ply2741 cell wall binding domain (CBD) responsible for binding to peptidoglycan were revealed by molecular docking and fluorescence-activated cell sorting (FACS) analysis. …”
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Pulmonary Bacterial Communities in Surgically Resected Noncystic Fibrosis Bronchiectasis Lungs Are Similar to Those in Cystic Fibrosis by Heather Maughan, Kristopher S. Cunningham, Pauline W. Wang, Yu Zhang, Marcelo Cypel, Cecilia Chaparro, D. Elizabeth Tullis, Thomas K. Waddell, Shaf Keshavjee, Mingyao Liu, David S. Guttman, David M. Hwang

“…We characterized and compared the pulmonary bacterial communities of cystic fibrosis (CF) and non-CF bronchiectasis patients using a culture-independent molecular approach. Methods. Bacterial 16S rRNA gene libraries were constructed from lung tissue of 10 non-CF bronchiectasis and 21 CF patients, followed by DNA sequencing of isolates from each library. …”
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Association Between GSK3β Gene Polymorphisms (rs334558 and rs3755557) with Schizophrenia Risk by Maryam Montazeri Dehbarez, Dormohammad Kordi Tamandani, Nasim Naeimi, Shahram Vaziri, Mohammad Shekari

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Ginsenosides 20R-Rg3 and Rg5 enriched black ginseng inhibits colorectal cancer tumor growth by activating the Akt/Bax/caspase-3 pathway and modulating gut microbiota in mice by Peng Yu, Weiyin Xu, Yanqi Li, Zhaoyang Xie, Simeng Shao, Jianing Liu, Ying Wang, Long Wang, Hongmei Yang

“…This study aims to evaluate the effectiveness of ginsenosides 20R-Rg3 and Rg5 enriched BG (Rg3/Rg5-BG), innovatively prepared by low temperature steam-heating process, against colorectal cancer (CRC), and elucidate its potential molecular mechanism. Interestingly, much higher concentrations of rare ginsenosides were detected in this unique BG than those in red ginseng, especially 20R-Rg3 and Rg5, which may contribute to treatment of CRC. …”
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Mitochondrial ROS modulate presynaptic plasticity in the drosophila neuromuscular junction by Irina Stavrovskaya, Bethany Kristi Morin, Stephen Madamba, Cliyahnelle Alexander, Alexis Romano, Samia Alam, Lucas Pavlov, Erna Mitaishvili, Pablo M. Peixoto

“…We propose the involvement of putative redox switches in AZ components as the molecular target of mitochondrial H2O2. These findings establish a novel framework for understanding the signaling role of mROS in presynaptic structural and functional plasticity, providing insights into redox-based mechanisms of neuronal communication.…”
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Fucosterol Protects against Concanavalin A-Induced Acute Liver Injury: Focus on P38 MAPK/NF-κB Pathway Activity by Wenhui Mo, Chengfen Wang, Jingjing Li, Kan Chen, Yujing Xia, Sainan Li, Ling Xu, Xiya Lu, Wenwen Wang, Chuanyong Guo

“…The aim of this study was to investigate the protective effects of fucosterol pretreatment on Concanavalin A- (ConA-) induced acute liver injury in mice, and to understand its molecular mechanisms. Materials and Methods. Acute liver injury was induced in BALB/c mice by ConA (25 mg/kg), and fucosterol (dissolved in 2% DMSO) was orally administered daily at doses of 25, 50, and 100 mg/kg. …”
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