Inhalation of patchouli essential oil alleviates airway inflammation in cigarette smoke-induced COPD mice by Yan Zhang, Rui Cao, Duo Wang, Qiulin Yue, Le Su, Kunlun Li, Baojun Li, Lin Zhao, Song Zhang

“…Current pharmacological interventions are ineffective in reversing these airflow limitations; In our study, we investigated the potential role of patchouli essential oil (PEO) in the treatment of COPD and its underlying molecular mechanisms, both in vitro and in vivo. To establish a cigarette smoke-induced COPD mice model, we exposed the mice to cigarette smoke (CS) and administered nasal drip of lipopolysaccharides (LPS). …”
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RNA sequence analysis landscape: A comprehensive review of task types, databases, datasets, word embedding methods, and language models by Muhammad Nabeel Asim, Muhammad Ali Ibrahim, Tayyaba Asif, Andreas Dengel

“…To enable large-scale RNA sequence analysis, empowerment of wet-lab experimental methods with Artificial Intelligence (AI) applications necessitates scientists to have a comprehensive knowledge of both DNA and AI fields. While molecular biologists encounter challenges in understanding AI methods, computer scientists often lack basic foundations of RNA sequence analysis tasks. …”
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Perforin-2 is dispensable for host defense against Aspergillus fumigatus and Candida albicans by Mariano A. Aufiero, Li-Yin Hung, De'Broski R. Herbert, Tobias M. Hohl

“…ABSTRACT Myeloid phagocytes are essential for antifungal immunity against pulmonary Aspergillus fumigatus and systemic Candida albicans infections. However, the molecular mechanisms underlying fungal clearance by phagocytes remain incompletely understood. …”
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Pathological roles of ubiquitination and deubiquitination systems in sepsis-induced myocardial dysfunction by Zhiping Wang, Simiao Sun, Lili Huang, Xinlong Chen, Huifen Xu, Hongwei Ma, Mingbing Xiao, Linhua Wang

“…Despite significant advances in understanding sepsis pathophysiology, the molecular mechanisms underlying SIMD remain incompletely elucidated. …”
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Highly sensitive, responsive, and selective iodine gas sensor fabricated using AgI-functionalized graphene by Zhuo Chen, Qiong Lei, Yinchang Ma, Jinrong Wang, Yuan Yan, Jun Yin, Jiaqiang Li, Jie Shen, Guanxing Li, Tingting Pan, Xinglong Dong, Bambar Davaasuren, Yaping Zhang, Jefferson Zhe Liu, Jun Tao, Yu Han

“…Abstract Radioactive molecular iodine (I2) is a critical volatile pollutant generated in nuclear energy applications, necessitating sensors that rapidly and selectively detect low concentrations of I2 vapor to protect human health and the environment. …”
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To be or not to be phosphorylated: understanding the role of Ebola virus nucleoprotein in the dynamic interplay with the transcriptional activator VP30 and the host phosphatase PP2... by Lennart Kämper, Ida Kuhl, Melina Vallbracht, Thomas Hoenen, Uwe Linne, Axel Weber, Petr Chlanda, Michael Kracht, Nadine Biedenkopf

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Metabolic deficiencies underlie reduced plasmacytoid dendritic cell IFN-I production following viral infection by Trever T. Greene, Yeara Jo, Carolina Chiale, Monica Macal, Ziyan Fang, Fawziyah S. Khatri, Alicia L. Codrington, Katelynn R. Kazane, Elizabeth Akbulut, Shobha Swaminathan, Yu Fujita, Patricia Fitzgerald-Bocarsly, Thekla Cordes, Christian Metallo, David A. Scott, Elina I. Zúñiga

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The Oil-Bearing Strata of Permian Deposits of the Ashal’cha Oil Field Depending on the Content, Composition, and Thermal Effects of Organic Matter Oxidation in the Rocks by Galina P. Kayukova, Anastasiya N. Mikhailova, Igor P. Kosachev, Dmitry A. Emelyanov, Mikhail A. Varfolomeev, Boris V. Uspensky, Alexey V. Vakhin

“…The features of group and hydrocarbon composition of extracts from rocks are revealed depending on their mineral composition and the content of organic matter in them. According to the molecular mass distribution of alkanes of normal and isoprenoid structure, extracts from rocks are differentiated according to three chemical types of oil: type A1, in which n-alkanes of composition C14 and above are present, and types A2 and B2, in which n-alkanes are destroyed to varying degrees by processes microbial destruction, which indicates a different intensity of biochemical processes in productive strata of Permian sediments. …”
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Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer by Jinbao Chen, Chenqi Wu, Kun Yu, Jinpei Liu, Jiahua Yang, Wei Li, Xiaoxia Tang, Yihai Shi, Ke Xu, Yi Chen, Xiaoyu Qin

“…Western blot and immunofluorescence were used to explore the potential molecular changes. BU can precisely regulate c-Myc expression by targeting SRC-3 in chemoresistant cells was confirmed by Western blot. …”
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Egfr Amplification Specific Gene Expression in Phyllodes Tumours of the Breast by Konstantin Agelopoulos, Christian Kersting, Eberhard Korsching, Hartmut Schmidt, Arno Kuijper, Christian August, Pia Wülfing, Joke Tio, Werner Boecker, Paul J. van Diest, Burkhard Brandt, Horst Buerger

“…The interplay between EGFR and caveolin-1, eps15, pAkt, mdm2 and pERK therefore seems to present a major molecular pathway in carcinogenesis and progression of breast phyllodes tumours.…”
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Enzimas hepáticas en pacientes de alto riesgo diagnosticados con la COVID-19 by Naivy Sánchez Vera, Danay Saavedra Hernández, Carlos Jorge Hidalgo Mesa, Maykel Aguila López, Yaneisy Negrín Medina, Iliana Rodríguez García

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Traditional medicine use and associated factors in chronic patients in Jamalpur, Bangladesh: a cross-sectional study by Mahmuda Akter Poli, Md Jamil Hossain, Ibrahim Kholil, Sumaya Yasmin, Bishwjit Bhowmick, Lakshmi Rani Kundu

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SIRT5‐mediated HOXA5 desuccinylation inhibits ferroptosis to alleviate sepsis induced‐lung injury by Lei Wang, Heng Fan, Min Sun, Ji‐Hui Ye

“…Cell viability, ferrous iron (Fe2+) level, and cellular lipid reactive oxygen species (ROS) were determined with Cell Counting Kit‐8 assay, iron assay kit, and BODIPY™ 665/676 molecular probe, respectively. HOXA5, ferroptosis suppressor protein 1 (FSP1), sirtuin 5 (SIRT5), and glutathione peroxidase 4 (GPX4) expressions were measured using western blotting and Real‐Time Quantitative Polymerase Chain Reaction (RT‐qPCR. …”
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Tau mediates the reshaping of the transcriptional landscape toward intermediate Alzheimer’s disease stages by Giacomo Siano, Giacomo Siano, Martina Varisco, Marco Terrigno, Congwei Wang, Arianna Scarlatti, Vincenzo Iannone, Marco Groth, Marie-Christine Galas, Jeroen J. M. Hoozemans, Alessandro Cellerino, Alessandro Cellerino, Antonino Cattaneo, Cristina Di Primio

“…In addition, we found that the chromatin architecture is affected by Tau during the progression of AD.DiscussionThese results provide new insights into the molecular mechanisms underlying early stages of AD development and highlight the central role of Tau and the contribution of nuclear Tau in this process.…”
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Improving the efficiency of an optical-to-terahertz converter using sapphire fibers by N. V. Zenchenko, D. V. Lavrukhin, I. A. Glinskiy, D. S. Ponomarev

“…As a photoconductive substrate, we used a semi-infinite LT-GaAs layer (low-temperature grown GaAs; GaAs layer grown by molecular beam epitaxy at a low growth temperature). …”
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Stem Cell Therapy for the Treatment of Amyotrophic Lateral Sclerosis: Comparison of the Efficacy of Mesenchymal Stem Cells, Neural Stem Cells, and Induced Pluripotent Stem Cells by Lauren Frawley, Noam Tomer Taylor, Olivia Sivills, Ella McPhillamy, Timothy Duy To, Yibo Wu, Beek Yoke Chin, Chiew Yen Wong

“…Current research targets molecular mechanisms of inflammation, excitotoxicity, aggregation-prone proteins, and proteinopathy. …”
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Identification of Differentially Expressed Genes and Signaling Pathways in Acute Myocardial Infarction Based on Integrated Bioinformatics Analysis by Da-Qiu Chen, Xiang-Sheng Kong, Xue-Bin Shen, Mao-Zhi Huang, Jian-Ping Zheng, Jing Sun, Shang-Hua Xu

“…This study may provide credible molecular biomarkers in terms of screening, diagnosis, and prognosis for AMI. …”
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IMA Genome - F13 by P. Markus Wilken, Janneke Aylward, Ramesh Chand, Felix Grewe, Frances A. Lane, Shagun Sinha, Claudio Ametrano, Isabel Distefano, Pradeep K. Divakar, Tuan A. Duong, Sabine Huhndorf, Ravindra N. Kharwar, H. Thorsten Lumbsch, Sudhir Navathe, Carlos A. Pérez, Nazaret Ramírez-Berrutti, Rohit Sharma, Yukun Sun, Brenda D. Wingfield, Michael J. Wingfield

“…These genomes provide a valuable resource for understanding the molecular processes in these economically important fungi.…”
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Transcriptomic Response of Arabidopsis thaliana to Pseudomonas syringae Infection: An In Silico Approach by Amir Ghaffar Shahriari, Mohamad Hamed Ghodoum Parizipour, Yaser Biniaz, Aminallah Tahmasebi, Fatemeh Gholizadeh

“…In contrast, the down-regulation of genes involved in the cellular and biosynthesis processes was observed. Regarding molecular function, 412 genes associated with kinase, catalase, and oxidoreductase activities were up-regulated in the bacteria-infected plants, while down-regulation of hydrolase and transferase activity genes was observed. …”
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SUGT1 is a prognostic biomarker and is associated with immune infiltrates in ovarian cancer by Linyan Ge, Xiu Liu, Lingyan Zhang, Jiaren Zhang, Guanghui Song

“…Conclusions All these results of this study show that SUGT1 is an important molecular component in immune infiltration in OC and may have a new significant prognostic role in OC.…”
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