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Next generation sequencing uncovers multiple miRNAs associated molecular targets in gallbladder cancer patients
Published 2023-11-01“…Next-generation sequencing has improved our understanding of molecular pathways in cancer, sparking interest in microRNA-based gene regulation. …”
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1303
Physical and molecular identification of fish and shrimp diseases in some farms of West Java, Banten and Jakarta, Indonesia
Published 2024-07-01“…The aims of this study was to identify the physical and molecular presence of infectious pathogens in fish and shrimp cultivated in several ponds in West Java, Banten and Jakarta. …”
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MOLECULAR DATING OF INTRASPECIFIC DIFFERENTIATION OF THE STOAT (MUSTELA ERMINEA) BASED ON THE VARIABILITY OF THE MITOCHONDRIAL ND2 GENE
Published 2015-01-01Subjects: Get full text
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Molecular Determination of Toxocara spp. Eggs Isolated from Public Parks and Playgrounds in Zahedan, Southeast Iran
Published 2024-01-01“…This study is aimed at eliciting the prevalence of Toxocara spp. eggs in public parks in Zahedan, southeast Iran, and providing new insight into the soil contamination rate in this area using microscopic and molecular methods. Methods. Based on five municipal districts, 240 soil samples were collected from public parks and playgrounds in Zahedan. …”
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Exploring the mechanism of Schisandra rubriflora in the treatment of polycystic ovary syndrome based on network pharmacology and molecular docking
Published 2025-01-01“…The aim of this study was to elucidate the effects of Schisandra rubriflora (S. rubriflora) on PCOS and its related mechanisms using network pharmacology, molecular docking and in vitro experiments. Materials and methods HERB database and SwissTargetPrediction database were used to obtain the active components and the targets of S. rubriflora. …”
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Drug molecular representations for drug response predictions: a comprehensive investigation via machine learning methods
Published 2025-01-01“…Abstract The integration of drug molecular representations into predictive models for Drug Response Prediction (DRP) is a standard procedure in pharmaceutical research and development. …”
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Role of Astrocytic Dysfunction in the Pathogenesis of Parkinson’s Disease Animal Models from a Molecular Signaling Perspective
Published 2020-01-01“…This article explores relevant evidence on the involvement of astrocytes in experimental PD neurodegeneration from a molecular signaling perspective. For a long time, astrocytic proliferation was merely considered a byproduct of neuroinflammation, but by the time being, it is clear that astrocytic dysfunction plays a far more important role in PD pathophysiology. …”
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Effects of Tremella fuciformis -Derived Polysaccharides with Different Molecular Weight on D-Galactose-Induced Aging of Mice
Published 2023-05-01“…All three TFPs were devoid of triple helix conformation and exhibited concentration- and molecular weight-dependent scavenging activity against radicals. …”
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Accelerating charge estimation in molecular dynamics simulations using physics-informed neural networks: corrosion applications
Published 2025-02-01“…Abstract Molecular Dynamics (MD) simulations are used to understand the effects of corrosion on metallic materials in salt brine. …”
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Exploring the inhibitory potential of xanthohumol on MEK1/2: a molecular docking and dynamics simulation investigation
Published 2024-12-01Subjects: Get full text
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Molecular aspects of cell-penetrating peptides: key amino acids, membrane partners, and non-covalent interactions
Published 2025-01-01“…The plasma membrane is complex in terms of molecular composition and structure. It separates the external environment from the cell interior and is composed of thousands of different lipids, proteins, and sulfated carbohydrates, all arranged in a complex and dynamic manner and at various length scales. …”
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THE MOLECULAR GENETIC STUDY OF KRIM-SAGHYZ (Taraxacum hybernum Steven) USING SSR, RAPD AND ISSR MARKERS
Published 2018-03-01“…In this regard, the purpose of our work was a comparative molecular-genetic characterization of T. hybernum from various habitats of the Crimean Peninsula using SSR, RAPD and ISSR markers. …”
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The Molecular Mechanism Underlying Continuous Exercise Training-Induced Adaptive Changes of Lipolysis in White Adipose Cells
Published 2015-01-01“…This review outlines the alterations in the lipolytic molecules of white adipocytes that result from ET, which includes the molecular regulation of TG lipases through the lipolytic cascade.…”
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Low Molecular Weight Fucoidan Can Inhibit the Fibrosis of Diabetic Kidneys by Regulating the Kidney Lipid Metabolism
Published 2021-01-01“…To inhibit fibrosis and reduce fat deposition, low molecular weight fucoidan (LMWF) may be used. Based on PCR and western blot analyses, LMWF can regulate the expression levels of important lipid metabolism regulators, thereby impeding the development of kidney fibrosis. …”
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1,5-Dichloroethanoanthracene Derivatives As Antidepressant Maprotiline Analogs: Synthesis, DFT Computational Calculations, and Molecular Docking
Published 2022-01-01“…In addition, the side chain of this aldehyde 2 was extended via the Wittig reaction to obtain the unsaturated ester 5 that was subjected to selective olefinic catalytic hydrogenation to obtain the corresponding saturated ester 6. Molecular docking simulation showed that all the compounds (1, 2, 5, and 6) have high antidepressant activities and form stable complexes with LeuT by inhibiting the neurotransmitter reuptake at the synapse and hence are good candidates as antidepressant drugs.…”
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