Characterization of tumor evolution by functional clonality and phylogenetics in hepatocellular carcinoma by Zeynep Kacar, Eric Slud, Doron Levy, Julián Candia, Anuradha Budhu, Marshonna Forgues, Xiaolin Wu, Arati Raziuddin, Bao Tran, Jyoti Shetty, Yotsawat Pomyen, Jittiporn Chaisaingmongkol, Siritida Rabibhadana, Benjarath Pupacdi, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Chirayu Auewarakul, Suleeporn Sangrajrang, Chulabhorn Mahidol, Mathuros Ruchirawat, Xin Wei Wang

“…Abstract Hepatocellular carcinoma (HCC) is a molecularly heterogeneous solid malignancy, and its fitness may be shaped by how its tumor cells evolve. …”
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Association of Xmn I Polymorphism and Hemoglobin E Haplotypes on Postnatal Gamma Globin Gene Expression in Homozygous Hemoglobin E by Supachai Ekwattanakit, Yuwarat Monteerarat, Suchada Riolueang, Kalaya Tachavanich, Vip Viprakasit

“…Patients and Methods. 80 individuals with molecularly confirmed homozygous Hb E were analyzed for the β globin haplotypes and Xmn I polymorphism using PCR-RFLPs. 74 individuals with complete laboratory data were further studied for association analyses. …”
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DNA metabarcoding technology for the identification of the fecal microbiome in patients with chronic stress by Abraham Eudes Pérez Urruchi, Lucy Eliana Ramírez Elizalde, Flor de María Zapata Cornejo, María Luisa Matalinares Calvet, Miluska Vanessa Baylon Cuba, Fredy Fabian Dominguez

“…The results, at the psychological test level, 20 people with chronic stress were diagnosed, on the other hand, at the metabarcoding level, specifically at the Gender level, the Asteroleplasma bacteria present only in the 20 healthy patients was molecularly identified. On the other hand, the bacteria Alistipes and Bifidobacterium were identified with greater predominance in the 20 patients with stress. …”
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Bases fisiológicas de la desfibrilación ventricular by Amanda Claudia Barco Lima, Belkys Caridad Pedroso Araujo, Diana Laura García Pérez, Víctor René Navarro Machado, Milagros León Regal

“…Se concluyó que las bases fisiológicas integran a las funciones celulares propias del corazón, las modificaciones físico-moleculares celulares que condicionan la arritmia o se generan por la hipoxia, a los cambios que sobre el tejido cardiaco produce el paso de electricidad y a las características de la onda de choque eléctrica del desfibrilador. …”
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Dissemination of IncQ1 Plasmids Harboring NTE_KPC-IId in a Brazilian Hospital by Camila Maria dos Santos Boralli, Julian Andres Paganini, Rodrigo Silva Meneses, Camila Pacheco Silveira Martins da Mata, Edna Marilea Meireles Leite, Anita C. Schürch, Fernanda L. Paganelli, Rob J. L. Willems, Ilana L. B. C. Camargo

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Lipopolysaccharide Inhibits the Channel Activity of the P2X7 Receptor by Elias Leiva-Salcedo, Claudio Coddou, Felipe E. Rodríguez, Antonello Penna, Ximena Lopez, Tanya Neira, Ricardo Fernández, Mónica Imarai, Miguel Rios, Jorge Escobar, Margarita Montoya, J. Pablo Huidobro-Toro, Alejandro Escobar, Claudio Acuña-Castillo

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Functional Characterization of Sesquiterpene Synthase from Polygonum minus by Su-Fang Ee, Zeti-Azura Mohamed-Hussein, Roohaida Othman, Noor Azmi Shaharuddin, Ismanizan Ismail, Zamri Zainal

“…Two transgenic lines, designated as OE3 and OE7, were further characterized, both molecularly and functionally. The transgenic plants demonstrated smaller basal rosette leaves, shorter and fewer flowering stems, and fewer seeds compared to wild type plants. …”
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Screening 27 Genotypes of Eggplant (Solanum melongena) for Resistance to Three Species of Begomovirus by Dian Yogi Noviana, Rudi Hari Murti, Panjisakti Basunanda, Ratih Wahyuni, Mustika Ajeng Kartini Putri Pertiwi

“…In a controlled environment, 27 eggplant genotypes were inoculated with the single of three Begomovirus species separately (molecularly confirmed), using Bemisia tabaci as a vector. …”
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DNA origami-designed 3D phononic crystals by Park Sung Hun, Park Haedong, Nam Jwa-Min, Ke Yonggang, Liedl Tim, Tian Ye, Lee Seungwoo

“…Furthermore, their lattice symmetry can be molecularly programmed to be at the highest level in a hierarchy of symmetry groups and numbers, which can facilitate the widening of the PnBG. …”
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Proline‐Selective Electrochemiluminescence Detecting a Single Amino Acid Variation Between A1 and A2 β‐Casein Containing Milks by Eunkyoung Kim, Chen‐Yu Chen, Monica J. Chu, Mya F. Hamstra, William E. Bentley, Gregory F. Payne

“…Further, the ECL‐method is Pro‐selective (vs molecularly‐selective like typical immunoassays) which should make it broadly useful for studying the role of proline in biology and especially useful for tracking the digestion of proline‐rich proteins in the diet.…”
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A novel 4-(1,3,4-thiadiazole-2-ylthio)pyrimidine derivative inhibits cell proliferation by suppressing the MEK/ERK signaling pathway in colorectal cancer by Li Weiwei, Yang Zhifu, Ding Likun, Wang Ying, Zhao Xian, Chu Jian Jie, Ji Qing, Yao Minna, Wang Jingwen

“…Colorectal cancer (CRC) is one of the most common types of malignant cancers worldwide. Although molecularly targeted therapies have significantly improved treatment outcomes, most of these target inhibitors are resistant. …”
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POTENCY OF SOURSOP LEAF EXTRACT AND CURCUMIN WITH MAGNETIC AND MUCUS-PENETRATING NANOPARTICLE AS COLORECTAL CANCER ALTERNATIVE THERAPY by Faiza Rahma Ebnudesita, Ayik Rochyatul Jannah, Savira Butsainah Dienanta, Reny I'tishom

“…Curcumin from turmeric extract has antioxidant, anti-inflammatory, antimutagenic, antiangiogenic, and anticancer effects. Curcumin works molecularly on cyclooxygenase-2 (COX-2) to prevent inflammation, thereby inhibit the growth of cancer cells and reducing the risk of metastasis. …”
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Supralinear dendritic integration in murine dendrite-targeting interneurons by Simonas Griesius, Amy Richardson, Dimitri Michael Kullmann

“…Here, we use patch-clamp electrophysiology, and two-photon calcium imaging and glutamate uncaging, to show that supralinear dendritic integration of near-synchronous spatially clustered glutamate-receptor mediated depolarization occurs in NDNF-positive neurogliaform cells and oriens-lacunosum moleculare interneurons in the mouse hippocampus. Supralinear summation was detected via recordings of somatic depolarizations elicited by uncaging of glutamate on dendritic fragments, and, in neurogliaform cells, by concurrent imaging of dendritic calcium transients. …”
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Unveiling the potential of Aspergillus terreus SJP02 for zinc remediation and its driving mechanism by Shobham, Vishalakshi Bhanot, Mamta, Sanjay Kumar Verma, Suresh Gupta, Jitendra Panwar

“…Isolate depicting highest potential was molecularly identified as Aspergillus terreus SJP02. …”
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dyphAI dynamic pharmacophore modeling with AI: a tool for efficient screening of new acetylcholinesterase inhibitors by Yasser Hayek-Orduz, Dorian Armando Acevedo-Castro, Dorian Armando Acevedo-Castro, Juan Sebastián Saldarriaga Escobar, Brandon Eli Ortiz-Domínguez, María Francisca Villegas-Torres, Paola A. Caicedo, Álvaro Barrera-Ocampo, Natalie Cortes, Edison H. Osorio, Andrés Fernando González Barrios

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Adenoma trabecular hialinizante de tiroides. Presentación de un caso by Miguel Morales Madrigal, Elodia Rivas Alpízar, Javier Martínez Navarro, Ileana Núñez Paredes

“…La importancia de su diagnóstico radica en el hecho que son interpretados por sus similitudes histológicas, inmunohistoquímica y moleculares con otras entidades, como cáncer papilar y medular de tiroides, de ahí que se haya decidido la presentación de este caso.…”
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Deciphering the nature and statistical optimization of antimicrobial metabolites of two endophytic bacilli by Raghda S. Isleem, Ahmed M. Eid, Saad El-Din Hassan, Khaled M. Aboshanab, Ghadir S. El-Housseiny

“…Two bacterial isolates, C6 and C11, were found to have a broad-spectrum antagonistic effect against four standard microbial strains and were molecularly identified using 16 S ribosomal RNA sequence analysis and deposited in a local culture collection as B. velezensis CCASU-C6, and B. subtilis CCASU-C11, respectively. …”
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Metformin Facilitates Osteoblastic Differentiation and M2 Macrophage Polarization by PI3K/AKT/mTOR Pathway in Human Umbilical Cord Mesenchymal Stem Cells by Min Shen, Huihui Yu, Yunfeng Jin, Jiahang Mo, Jingni Sui, Xiaohan Qian, Tong Chen

“…Mechanically, we found that metformin-treated M2 macrophages possessed more potent osteoinductive capacity in our coculture system. Molecularly, these metformin-stimulated M2 macrophages facilitated osteogenesis via activating the PI3K/AKT/mTOR pathway. …”
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ADVANCES IN REPRODUCTIVE TECHNOLOGIES IN CATTLE: FROM ARTIFICIAL INSEMINATION TO CLONING by M Bertolini, LR Bertolini

“…Estas tecnologías se intercalan las unas con las otras y con las herramientas moleculares actuales, dependen completamente de las generaciones de tecnologías previas. …”
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Pre-probiotic effects of different bacterial species in aquaculture: behavioral, hematological and oxidative stress responses by Alak Gonca, Kotan Recep, Uçar Arzu, Parlak Veysel, Atamanalp Muhammed

“…In this study, acute applications of four different molecularly identified bacterial species – Brevibacillus brevis FD-1 (A), Pseudomonas fluorescens FDG-37 (B), Bacillus sphaericus FD-48 (C), and B. amyloliquefaciens TV-17C (D), with potential in aquaculture, were tested in rainbow trout (Oncorhynchus mykiss) under static conditions. …”
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