Design, Synthesis, Molecular Docking, and Antibacterial Evaluation of Some Novel Flouroquinolone Derivatives as Potent Antibacterial Agent by Mehul M. Patel, Laxman J. Patel

Get full text

A structural genomics approach to investigate Dystrophin mutations and their impact on the molecular pathways of Duchenne muscular dystrophy by Abdelbaset Mohamed Elasbali, Farah Anjum, Osama A. AlKhamees, Waleed Abu Al-Soud, Mohd Adnan, Anas Shamsi, Md. Imtaiyaz Hassan

“…Six substitutions (N26H, N26K, G47W, D98G, G109A, and G109R) were predicted to decrease protein solubility and were located in minimally frustrated regions, potentially compromising Dystrophin functionality and contributing to DMD pathogenesis.ConclusionThis study provides novel insights into the molecular mechanisms of DMD, highlighting specific mutations that disrupt Dystrophin’s solubility and function. …”
Get full text

Molecular Characteristics and Antibiotic Resistance Profiles of Klebsiella Isolates in Mthatha, Eastern Cape Province, South Africa by Sandeep Vasaikar, Larry Obi, Isaac Morobe, Mary Bisi-Johnson

Get full text

Adsorption of CO/CH Mixtures in a Molecular Model of Activated Carbon through Monte Carlo Simulations by Alberto G. Albesa, Matías Rafti, José L. Vicente, Hernán Sánchez, Pablo Húmpola

Get full text

Ultrasonic Analysis of Peptide- and Antibody-Targeted Microbubble Contrast Agents for Molecular Imaging of αβ-Expressing Cells by Paul A. Dayton, David Pearson, Jarrod Clark, Scott Simon, Patricia A. Schumann, Reena Zutshi, Terry O. Matsunaga, Katherine W. Ferrara

“…Molecular Imaging…”
Get full text

Identification of GBN5 as a molecular biomarker of pan-cancer species by integrated multi-omics analysis by Qian Guo, Xinxin Zhong, Zihan Dang, Baiquan Zhang, Zixin Yang

Get full text

Molecular Dynamics Simulations of CO2 Molecules in ZIF-11 Using Refined AMBER Force Field by W. Wongsinlatam, T. Remsungnen

“…The site-site radial distribution functions and the molecular distribution plots simulations indicate that all hydrogen atoms are favored binding site of CO2 molecules. …”
Get full text

A Universal Analysis Pipeline for Hybrid Capture-Based Targeted Sequencing Data with Unique Molecular Indexes by Min-Jung Kim, Si-Cho Kim, Young-Joon Kim

Subjects: Get full text

TREM‑1 as a Potential Coreceptor in Norovirus Pathogenesis: Insights from Transcriptomic Analysis and Molecular Docking by Mike Telemaco Contreras Colmenares, Amanda de Oliveira Matos, Pedro Henrique dos Santos Dantas, José Rodrigues Do Carmo Neto, Bruno Júnior Neves, Luiz Gustavo Araújo Gardinassi, Marcelle Silva-Sales, Helioswilton Sales-Campos

Get full text

A cross-entropy corrected hybrid multiconfiguration pair-density functional theory for complex molecular systems by Rulin Feng, Igor Ying Zhang, Xin Xu

Get full text

Effectiveness of Contrast Agents and Molecular Indicators in Alzheimer's Diagnosis Through PET and SPECT Imaging on Animal Models by Yasaman Abaszadeh, Ramin Ardalani, Athena Dehghan Najm Abadi

Subjects: Get full text

Molecular Engineering of Direct Activated NIR-II Chemiluminescence Platform for In Vivo Chemiluminescence-fluorescence Duplex Imaging by Zhongxiang Chen, Qian Li, Ying Wu, Jianyong Liu, Luntao Liu, Lichao Su, Rongrong Wu, Jibin Song

Get full text

Effects of Exercise Training on Molecular Markers of Lipogenesis and Lipid Partitioning in Fructose-Induced Liver Fat Accumulation by Siham Yasari, Denis Prud'homme, Frédérique Tesson, Marek Jankowski, Jolanta Gutkowska, Emile Levy, Jean-Marc Lavoie

“…It is concluded that exercise training does not significantly affect fat accumulation and the molecular expression of genes involved in lipogenesis after fasting and fructose refeeding but does modify the partitioning of lipids so as to provide more unsaturated fatty acids in liver without affecting liver fat content.…”
Get full text

Treatment of intractable pruritus in patients with cholestasis with molecular adsorbents recirculating system dialysis: a case series by Magdalena Antoszewska, Piotr Spychalski, Gerda Elisabeth Villadsen, Niels Kristian Muff Aagaard

Get full text

Identification of Molecular Substrate for the Attenuation of Anxiety: A Step Toward the Development of Better Anti-Anxiety Drugs by Uwe Rudolph

Get full text

Clinical, Radiographic, and Molecular Analysis of Patients with X-Linked Hypophosphatemic Rickets: Looking for Phenotype–Genotype Correlation by Marco A. Olivas-Valdez, Armando Blanco-López, Daniela Velázquez-Arestegui, Teresita Vera-Zazueta, Douglas Colmenares-Bonilla, Lilian Reyes-Morales, Miguel A. Blanco-Uriarte, Lucero Monterde-Cruz, Alberto Hidalgo-Bravo

“…Methods: We recruited a total of 130 patients of Mexican Mestizo origin with confirmed molecular diagnosis of XLH; this is one of the largest cohorts reported. …”
Get full text

Comparative transcriptome analysis reveals molecular mechanisms of resistance in Chinese cabbage to Plasmodiophora brassicae pathotype 11 by Yue Qiu, Yue Qiu, Yue Qiu, Jinhao Zhang, Jinhao Zhang, Chunju Deng, Chunju Deng, Jiasheng Yuan, Jiasheng Yuan, Bowen Wang, Bowen Wang, Han Meng, Han Meng, Mohamed Mohany, Liting Zeng, Liting Zeng, Lanfang Wei, Lanfang Wei, Waqar Ahmed, Guanghai Ji, Guanghai Ji

“…However, the varied response mechanisms exhibited by hosts to pathotype 11 at a molecular level are still unclear.Methods and resultsThis study investigated the resistance response and underlying molecular mechanism of two Chinese cabbage (Brassica rapa) varieties (JP and 83-1) to P. brassicae pathotype 11 through comparative transcriptome analysis and microscopic study. …”
Get full text

AXL inhibitors selected by molecular docking: Option for reducing SARS-CoV-2 entry into cells by Galindo-Hernández Octavio, Vique-Sánchez José Luis

Subjects: Get full text

Molecular Hydrogen Modulates T Cell Differentiation and Enhances Neuro-Regeneration in a Vascular Dementia Mouse Model by Dain Lee, Hyunjun Jo, Jong-Il Choi

Subjects: Get full text

Integrated serum metabolomics and network pharmacology reveal molecular mechanism of Qixue Huazheng formula on peritoneal fibrosis by Xiaohui Meng, Xiaohui Meng, Li Sheng, Yongqing You, Yongqing You, Huibo Dai, Manshu Yu, Funing Wang, Funing Wang, Ziren Zhou, Ziren Zhou, Yun Shan, Meixiao Sheng

“…Metabolite-target network and molecular docking analyses revealed that QXHZF can bind to estrogen receptor 1 (ESR1) and rapidly accelerated fibrosarcoma 1 (RAF1) through its components. …”
Get full text