A Penalized Linear and Nonlinear Combined Conjugate Gradient Method for the Reconstruction of Fluorescence Molecular Tomography by Shang Shang, Jing Bai, Xiaolei Song, Hongkai Wang, Jaclyn Lau

“…In this paper, a penalized linear and nonlinear combined conjugate gradient method for the reconstruction of fluorescence molecular tomography (FMT) is presented. The algorithm combines the linear conjugate gradient method and the nonlinear conjugate gradient method together based on a restart strategy, in order to take advantage of the two kinds of conjugate gradient methods and compensate for the disadvantages. …”
Get full text

Deep learning for predicting prognostic consensus molecular subtypes in cervical cancer from histology images by Ruoyu Wang, Gozde N. Gunesli, Vilde Eide Skingen, Kari-Anne Frikstad Valen, Heidi Lyng, Lawrence S. Young, Nasir Rajpoot

“…This study proposes an end-to-end deep learning framework to predict consensus molecular subtypes (CMS) in HPV-positive cervical squamous cell carcinoma (CSCC) from H&E-stained histology slides. …”
Get full text

Identificación molecular de patrones genéticos en distintas muestras de arándano (vaccinium sp.) by M.C. Martínez, M.I. Plata Tamayo, H.E. Hopp

Subjects: Get full text

ErbB4 as a Potential Molecular Target in the Treatment of Esophageal Squamous Cell Cancers by Ke Zhao, Bao-Jun Chen, Zhi-Guo Chen

“…Taken together, miRNA-140-5p could act as a potential molecular target in ErbB4 overexpressing ESCC cell lines paving the way for effective esophageal cancer treatment.…”
Get full text

Molecular Understanding of the Role of Catalyst Particle Arrangement in Local Mass Transport Resistance for Fuel Cells by Aoxin Ran, Linhao Fan, Chasen Tongsh, Jiaqi Wang, Zhengguo Qin, Qing Du, Meng Ni, Kui Jiao

“…Herein, using a unique method coupling Hybrid Reverse Monte Carlo, molecular dynamics simulations, and experimental measurements, a Pt particle arrangement strategy is proposed to reduce local oxygen transport resistance, based on a molecular‐level understanding of its impact. …”
Get full text

Molecular Signatures of Humic Acids from Different Sources as Revealed by Ultrahigh Resolution Mass Spectrometry by Shuai Qin, Chengbin Xu, Yingzi Xu, Yingchen Bai, Fei Guo

“…JFHA, SRHA, and LEHA from soil, river, and leonardite, respectively, are arranged in order from the lowest to highest degree of humification, according to molecular unsaturation and aromaticity of HAs. Soil HA is more labile and contains many large molecular weight compounds with low unsaturation. …”
Get full text

Evaluation and molecular modelling of bis-Schiff base derivatives as potential leads for management of diabetes mellitus by Daoud Safa, Thiab Samar, Jazzazi Taghreed M. A., Al-Shboul Tareq M. A., Ullah Saeed

Get full text

Molecular Species Disturbing the Fluid–Solid Phase Transition of Nitrogen Adsorbed on Graphite: Importance of Aromaticity by Tsuyoshi Yano, Shinya Kamakura, Akari Ikeda, Hiromu Asada

“…These species were, in fact, found to have no significant effect. This implies that molecular properties such as cation acceptance and electron transfer are of no importance, whereas the aromaticity of co-existing species plays a crucial role in disturbing the phase behaviour of N 2 .…”
Get full text

Molecular surface descriptors to predict antibody developability: sensitivity to parameters, structure models, and conformational sampling by Eliott Park, Saeed Izadi

“…Here, we present a set of molecular surface descriptors specifically designed for predicting antibody developability. …”
Get full text

Author Correction: A molecular basis for spine color morphs in the sea urchin Lytechinus variegatus by Maria Wise, Madison Silvia, Gerardo Reyes, Rushane Dunn, Thomas M. Onorato, Cosmo Pieplow, Aidan Furze, El Hebert, Nathalie Oulhen, Dan Ritschoff, David R. McClay, Gary Wessel

Get full text

ER-Mitochondria Crosstalk during Cerebral Ischemia: Molecular Chaperones and ER-Mitochondrial Calcium Transfer by Yi-Bing Ouyang, Rona G. Giffard

“…Here, we review recent research on cerebral ischemia and MAM, with a focus on molecular chaperones and ER-mitochondrial calcium transfer.…”
Get full text

Response to: Comment on Genetic Ancestry-Specific Molecular and Survival Differences in Admixed Breast Cancer Patients by Alexandra E. Hernandez, MD, MPH, Brandon Mahal, MD, Aristeidis G. Telonis, PhD, Maria Figueroa, MD, Neha Goel, MD, MPH

Get full text

Molecular underpinnings of exceptional response in primary malignant melanoma of the esophagus to anti-PD-1 monotherapy by Yu Chen, Xuan Wang, Jie Dai, Li Zhou, Xuefeng Xia, Jun Guo, Xue Bai, Lu Si, Bixia Tang, Chuanliang Cui, Xiaoting Wei, Xinan Sheng, Siming Li, Zhihong Chi, Lili Mao, Bin Lian, Xieqiao Yan, Yan Kong, Caili Li, Xuan Gao, Lirui Tang, Linzi Sun, Zhonghui Qi, Zelong Xu

“…In this study, we retrospectively analyzed the efficacy of anti-programmed death (PD)-1 in patients with PMME and explored its molecular basis.Methods The response and survival of patients with PMME and NEMM under anti-PD-1 monotherapy were retrospectively analyzed. …”
Get full text

Interaction of norsecurinine-type monomeric and dimeric alkaloids with α-tubulin: a molecular docking study by Gérard Vergoten, Christian Bailly

“…Royle, was investigated using molecular docking. Methods: Two molecular models were initially compared for the binding of securinine to α/β-tubulin. …”
Get full text

MicroRNAs signatures as potential molecular markers in mild cognitive impairment: a meta-analysis by Natalia Vargas-Rondón, Yeimy González-Giraldo, Ángela Y. García Fonseca, Janneth Gonzalez, Andrés Felipe Aristizabal-Pachon

“…Due to their biological characteristics, microRNAs (miRNAs) are potential candidates as non-invasive molecular markers for the identification and assessment of MCI progression. …”
Get full text

Preparation of Surface Molecularly Imprinted Polymers for Selective Removal and Determination of Sulphamethoxazole from Aqueous Media by Pengfei Ma, Zhiping Zhou, Wanzhen Xu, Ting Fan, Wenming Yang

“…Different functional monomers (4-vinylpyridine, acrylamide and methacrylic acid) and different cross-linkers (ethylene glycol dimethacrylate and N,N'-methylenebisacrylamide) were selected to synthesize different kinds of molecularly imprinted polymers (MIPs) and their corresponding non-imprinted polymers. …”
Get full text

Extracellular cold-inducible RNA-binding protein in CNS injury: molecular insights and therapeutic approaches by Dmitriy Lapin, Archna Sharma, Ping Wang

“…Inflammatory secondary injury is incited by damage-associated molecular patterns (DAMPs) which signal a variety of resident CNS cells and infiltrating immune cells. …”
Get full text

Assessing the Roles of Molecular Markers of Antimalarial Drug Resistance and the Host Pharmacogenetics in Drug-Resistant Malaria by Peter Hodoameda, Nancy Odurowah Duah-Quashie, Neils Ben Quashie

Get full text

Clinical study, network pharmacology, and molecular docking of Kunxian capsule in treating idiopathic membranous nephropathy by Jia Lv, Xinyu Gao, Lihua Liu, Libing He, Geng Tian, Xuehong Lu

Subjects: Get full text

Composite odontoma: An enigmatic impeder to the permanent teeth – Report of two cases with emphasis on molecular pathogenesis by Vasanthi Vinoth, Ramesh Kumar Annasamy, Rajkumar Krishnan, Velavan Krishnan

Get full text