Relationship between enriched environment and neurodegeneration: a review from mechanism to therapy by Yuan-qiao Xu, Yanjiao Chen, Jia-xin Xing, Jun Yao

“…We discussed the molecular underpinnings of the effects of EE, including modulation of key signaling pathways such as extracellular regulated kinase 1/2 (ERK1/2), mitogen-activated protein kinases (MAPK), and AMPK/SIRT1, which were implicated in neuroprotection and synaptic plasticity. …”
Get full text

Suboptimal Greedy Power Allocation Schemes for Discrete Bit Loading by Waleed Al-Hanafy, Stephan Weiss

“…We consider low cost discrete bit loading based on greedy power allocation (GPA) under the constraints of total transmit power budget, target BER, and maximum permissible QAM modulation order. Compared to the standard GPA, which is optimal in terms of maximising the data throughput, three suboptimal schemes are proposed, which perform GPA on subsets of subchannels only. …”
Get full text

Optimal Resource Allocation and VCG Auction-Based Pricing for H.264 Scalable Video Quality Maximization in 4G Wireless Systems by Shreyans Parakh, Aditya K. Jagannatham

“…Subsequently, we derive the closed form solution of the optimal H.264 scalable video quantization parameter for sum video quality maximization in unicast and multicast 4G WiMAX adaptive modulation and coding (AMC) scenarios. We also formulate a Vickrey-Clarke-Groves (VCG) auction-based time-frequency (TF) resource pricing scheme for dynamic bitrate allocation and simultaneous prevention of video quality degradation by malicious users for H.264-based scalable video transmission. …”
Get full text

Reconfigurable Articulated Robot Using Android Mobile Device by A.H. Rajpar, Ahmad. E. Eladwi, Imran Ali, Mohamed Bashir Ali Bashir

“…An Arduino Un R3 board is used to control the movement of the links via a pulse width modulation method. We introduce a set of conveniently composed kinematic and dynamic mathematical models for positioning the robot’s arms and, in our results and discussion section, calculate and report the torque required to move each joint.…”
Get full text

Nonlinear Demodulation and Channel Coding in EBPSK Scheme by Xianqing Chen, Lenan Wu

“…The extended binary phase shift keying (EBPSK) is an efficient modulation technique, and a special impacting filter (SIF) is used in its demodulator to improve the bit error rate (BER) performance. …”
Get full text

Research progress on early intervention of postoperative scar by SHEN Si, LI Zhouna, JIN Zhehu

“…Because of the big challenge in the treatment of scars, early intervention strategies, such as vascular sealing, modulation of inflammatory factors, and tension reduction, can expedite the maturation process of postoperative scars while decreasing the incidence of pathological scars. …”
Get full text

All-Optical Switching Based on the Plasma Channel Induced by Laser Pulses by Chao Tan, Binliang Hu, Shiping Zhan, Yonghua Hu, Bin Zhong

“…We can infer the dark spot shape in the modulated signal laser through the intensity profile of control laser beam. …”
Get full text

Detailed Theoretical Model for Adjustable Gain-Clamped Semiconductor Optical Amplifier by Lin Liu, Craig Michie, Anthony E. Kelly, Ivan Andonovic

“…Simulations and comparisons with steady-state and dynamic gain modulation experimental performance are given which validate the model.…”
Get full text

Ultrafast Airy Beam Generation with a Mode-Locked Fiber Laser by Silin Guo, Yajun Lou, Cai Yue, Xinhai Zhang, Fan Zhang

“…A diffractive optical element is placed inside the laser cavity and applies phase modulation on the pulses propagating in the cavity. …”
Get full text

The Dynamicity of the Oxytocin Receptor in the Brain May Trigger Sensory Deficits in Autism Spectrum Disorder by Claudia Camerino

“…Recent studies indicate that Oxt triggers muscle contraction modulating thermogenesis, while abnormal thermoregulation results in sensory deficits, as in ASD. …”
Get full text

High-Speed Wireline Links—Part I: Modeling by Hossein Shakiba, Davide Tonietto, Ali Sheikholeslami

“…In a wireline link, we wish to model a wide variety of architectures and optimize their parameters, such as the feedforward equalizer and decision feedback equalizer tap coefficients, continuous-time linear equalizer frequency response, termination impedances, and possibly maximum-likelihood sequence estimation parameters, for a given channel and within a given set of constraints as dictated by the application requirements so as to minimize the link’s bit error rate. The modulation can be any of the PAM signaling schemes, such as NRZ or 4-PAM. …”
Get full text

Single‐stage AC–DC voltage regulator for 15 W wireless charging by X. Bai, Z. Kong, L. Siek

“…Unlike the traditional two‐stage AC–DC regulator, a pulse‐width modulation control algorithm is integrated to switch the working mode of an active rectifier between a charging mode and a zero mode to maintain the output voltage at 5 V. …”
Get full text

A Single DC Source Generalized Switched Capacitors Multilevel Inverter with Minimal Component Count by Kasinath Jena, Dhananjay Kumar, B. Hemanth Kumar, K. Janardhan, Arvind R. Singh, Raj Naidoo, Ramesh C. Bansal

“…At dynamic-loaded situations, the performance of the proposed SCMLI with dynamic modulation index and switching frequency is tested.…”
Get full text

Medical Gases: A Novel Strategy for Attenuating Ischemia—Reperfusion Injury in Organ Transplantation? by Arunotai Siriussawakul, Lucinda I. Chen, John D. Lang

“…In recent years, inhaled nitric oxide, carbon monoxide, and hydrogen sulfide have been increasingly explored as plausible novel medical gases that can attenuate IRI via multiple mechanisms, including microvascular vasorelaxation, reduced inflammation, and mitochondrial modulation. Here, we review recent advances in research utilizing inhaled nitric oxide, carbon monoxide, and hydrogen sulfide in animal and human studies of IRI and postulate on its future applications specific to solid organ transplantation.…”
Get full text

Grassmannian Constellation Based on Antipodal Points and Orthogonal Design and Its Simplified Detecting Algorithm by Li Peng, Dacong Hu, Lin Zhang, Zhen Qin

“…This study presents a framework of the unitary space time modulation (USTM) constellation based on antipodal points over Grassmannian manifold. …”
Get full text

AM3, an Oral BRM: Protective Agent against Iatrogenic Bone-Marrow and Liver Damage in Breast Cancer Patients under Conventional Adjuvant Radiochemotherapy by Vicente G Villarrubia, Paula Marquez, Jose Cobo, Guillermo J Sada

“…Finally, studies on acute-phase reactants, such as C-reactive protein, IgA. and factors B, C'3, and C'5 of the complement system, suggest that a modulation of hepatic inflammatory responses by AM3 appears to be essential for clinical effects described.…”
Get full text

Impact of Incretin-Based Therapies on Adipokines and Adiponectin by Habib Yaribeygi, Mina Maleki, Stephen L. Atkin, Tannaz Jamialahmadi, Amirhossein Sahebkar

“…In this review, we propose that incretin-based therapy may function through adipokine modulation that may result in pharmacologic properties beyond their direct antidiabetic effects, resulting in better management of diabetes and diabetes-related complications.…”
Get full text

Advances in intrahepatic and extrahepatic vascular dysregulations in cirrhotic portal hypertension by Yanqiu Li, Bingbing Zhu, Ke Shi, Yu Lu, Xuanwei Zeng, Yongqi Li, Qun Zhang, Ying Feng, Xianbo Wang

“…Additionally, therapeutic strategies targeting these vascular mechanisms are diverse, including improvement of sinusoidal microcirculation, therapies targeting hepatic stellate cells activation, and pharmacological modulation of systemic vascular tone. Therefore, in this review, we will discuss the vascular-related mechanisms and treatment progress of portal hypertension in cirrhosis to provide a new theoretical basis and practical guidance for clinical treatment.…”
Get full text

Experimental evidence-based construction of electroacupuncture for ischemic stroke: a meta-analysis and systematic review by Yaoguang Guo, Sihan Hu, Sihan Hu, Shiman Luo, Lang Tu, Yao Tang, Fang Zeng, Fang Zeng, Fang Zeng

“…The heterogeneity of the included studies points to complex underlying mechanisms, potentially involving modulation of apoptotic pathways and cerebral blood flow.ConclusionThis meta-analysis substantiates the neuroprotective potential of EA in ischemic stroke models, primarily through apoptosis modulation and possibly through improved cerebral perfusion. …”
Get full text

cGAS/STING signaling pathway in gynecological malignancies: From molecular mechanisms to therapeutic values by Danyang Zhang, Bingxue Zhang

“…It explores interactions between DNA damage response pathways and immune modulation, highlighting the impact of cGAS/STING activation or suppression in ovarian, cervical, and endometrial cancers. …”
Get full text