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1881
Disulfidptosis as a key regulator of glioblastoma progression and immune cell impairment
Published 2025-01-01“…SMC4 inhibition reduced LN299 cell migration and increased chemotherapy sensitivity, decreasing CD4 and CD8 T cell activation.ConclusionsDisulfidptosis-Tex genes are pivotal in glioblastoma progression and immune interactions, offering new avenues for improving anti-glioblastoma therapies through modulation of T cell exhaustion.…”
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1882
Vaginal Microbial Environment Skews Macrophage Polarization and Contributes to Cervical Cancer Development
Published 2022-01-01“…As a whole, Peptostreptococcus anaerobius-induced macrophage facilitates cervical cancer development through modulation of VEGF expression.…”
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1883
A Novel Hybrid T-Type Three-Level Inverter Based on SVPWM for PV Application
Published 2018-01-01“…At the same time, the space vector pulse width modulation (SVPWM) method is used to simulate the proposed topology in the MATLAB/SIMULINK platform, while the loss of each semiconductor switch is calculated using MELCOSIM software. …”
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1884
Modeling Dendrimers Charge Interaction in Solution: Relevance in Biosystems
Published 2014-01-01“…The finding of the presented results outlines the important role of the dendrimer charge and the solvent conditions in regulating, through the modulation of the electrostatic interaction potential, great part of the main structural properties. …”
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1885
Irradiance Scintillation Index for a Gaussian Beam Based on the Generalized Modified Atmospheric Spectrum with Aperture Averaged
Published 2016-01-01“…This paper also examines the effects of the irradiance scintillation on the performance of the point-to-point optical wireless communication system with intensity modulation/direct detection scheme.…”
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1886
Continuous Fuel Level Sensor Based on Spiral Side-Emitting Optical Fiber
Published 2012-01-01“…This sensor operates on the modulation of the light intensity in fiber, which is caused by the cladding’s acceptance angle change when it is immersed in fuel. …”
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1887
The crucial role of 5hmC in neuroprotection and repair after cerebrovascular injury
Published 2024-07-01“…The discussion delves into the dynamic interaction between hydroxymethylation and important pathways in neuroprotection, such as the modulation of excitotoxicity and cellular metabolism, resolution of inflammation, and mitigation of oxidative stress. …”
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1888
A Method against Interrupted-Sampling Repeater Jamming Based on Energy Function Detection and Band-Pass Filtering
Published 2017-01-01“…Interrupted-sampling repeater jamming (ISRJ) is a new kind of coherent jamming to the large time-bandwidth linear frequency modulation (LFM) signal. Many jamming modes, such as lifelike multiple false targets and dense false targets, can be made through setting up different parameters. …”
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1889
On Some Sampling-Related Frames in U-Invariant Spaces
Published 2013-01-01“…This general setting includes, in particular, shift-invariant or modulation-invariant subspaces in L2ℝ, where these frames are intimately related to the generalized sampling problem. …”
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1890
A Review of the Science of Colorful, Plant-Based Food and Practical Strategies for “Eating the Rainbow”
Published 2019-01-01“…These phytonutrients have known pleiotropic effects on cellular structure and function, ultimately resulting in the modulation of protein kinases and subsequent epigenetic modification in a manner that leads to improved outcomes. …”
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1891
The Role of Bacteria and Pattern Recognition Receptors in GvHD
Published 2010-01-01“…Gastrointestinal decontamination and neutralization of endotoxin have been used to interfere with this early axis of activation with some success but more specific approaches of modulation of innate immunity are needed for further improvement of clinical outcome.…”
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1892
Identifying mechanisms of tropical cyclone generated orographic precipitation with Doppler radar and rain gauge observations
Published 2025-01-01“…These rapidly evolving scenarios represent a secondary contributor to the modulation of precipitation intensities. The results from the study provide important insights into the relative importance of the different processes of orographically enhanced precipitation for TCs.…”
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1893
The Value of Desmethylclozapine and Serum CRP in Clozapine Toxicity: A Case Report
Published 2012-01-01“…In a medical emergency situation, differentiating between a toxic clozapine ingestion and an infection-induced toxicity might be hindered by associated CNS changes and by the clozapine modulation of the inflammatory process. This may delay prompt initiation of a tailored treatment strategy. …”
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1894
Cytokines and Angiogenesis in the Corpus Luteum
Published 2013-01-01“…Using the mare CL as a model, reports on locally produced cytokines, such as tumor necrosis factor α (TNF), interferon gamma (IFNG), or Fas ligand (FASL), pointed out their role on angiogenic activity modulation throughout the luteal phase. Thus, the main purpose of this review is to highlight the interaction between immune, endothelial, and luteal steroidogenic cells, regarding vascular dynamics/changes during establishment and regression of the equine CL.…”
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1895
Dual-Wavelength Passively Q-Switched Erbium-Doped Fiber Laser Incorporating Calcium Carbonate Nanoparticles as Saturable Absorber
Published 2023-01-01“…The properties of the SA were examined experimentally, and its modulation depth is approximately 47%. As the pump power increased from 180 mW to 270 mW and the pulse repetition rate increased from 12.67 kHz to 21.3 kHz, the corresponding pulse width decreased from 35.27 μs to 18.74 μs. …”
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1896
Performance Analysis of MIMO-STBC Systems with Higher Coding Rate Using Adaptive Semiblind Channel Estimation Scheme
Published 2014-01-01“…STBCs with higher code rates have been simulated for different modulation schemes using MATLAB environment and the simulated results have been compared in the semiblind environment which shows the improvement even in highly correlated antenna arrays and is found very close to the condition when channel state information (CSI) is known to the channel.…”
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1897
Dietary peptides in aging: Evidence and prospects
Published 2020-03-01“…Food derived bioactive peptides are characterized modulators of these pathways, while some verified in vivo and even clinically approved, and numerous others are under development. …”
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1898
Repeated Long-Term DT Application in the DEREG Mouse Induces a Neutralizing Anti-DT Antibody Response
Published 2016-01-01“…Genetic tools exploiting the foxp3 locus including bacterial artificial chromosome- (BAC-) transgenic DEpletion of REGulatory T cells (DEREG) mice have provided essential information on Treg biology and the potential therapeutic modulation of tolerance. In DEREG mice, Foxp3+ Tregs selectively express enhanced green fluorescent protein (eGFP) and diphtheria toxin (DT) receptor, allowing for the specific depletion of Tregs through DT administration. …”
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1899
The Role of 5-Lipoxygenase and Leukotrienes in Shock and Ischemia-Reperfusion Injury
Published 2007-01-01“…In particular, several data indicate that LTs regulate neutrophil trafficking in damaged tissue in shock and ischemia-reperfusion, mainly through the modulation of adhesion molecule expression. This concept may provide new insights into the interpretation of the protective effect of 5-LO inhibition, which may be useful in the therapy of pathological conditions associated with septic and nonseptic shock and ischemia-reperfusion injury.…”
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1900
Bionic Control of Cheetah Bounding with a Segmented Spine
Published 2016-01-01“…Besides, the vestibular modulation could perceive the pitching angle of the trunk. …”
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