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Histone lysine crotonylation accelerates ACSL4-mediated ferroptosis of keratinocytes via modulating autophagy in diabetic wound healing
Published 2025-03-01“…The ACSL4 knockdown was achieved using adenovirus in wounds to examine the impact of ferroptosis modulation on healing diabetic wounds. MB-3 was utilized to block the H3K27 crotonylation (H3K27cr) in order to clarify the regulatory function of crotonylation in both autophagy and ferroptosis. …”
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1063
A dataset for tactile textures on uneven surfaces collected using a BioIn-Tacto sensing moduleMendeley Data
Published 2025-04-01“…As a result, we are driven to create a dataset from the signals collected by a bioinspired multimodal tactile sensing module, as a robotic probe dynamically makes contact with 12 different tactile textures. …”
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1064
Posttranslational Nitration of Tyrosine Residues Modulates Glutamate Transmission and Contributes to N-Methyl-D-aspartate-Mediated Thermal Hyperalgesia
Published 2013-01-01“…The broader implication of our findings reinforces the notion that free radicals may contribute to various forms of pain events and the importance of the development of new pharmacological tool that can modulate the glutamate transmission without blocking its actions directly.…”
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Trigonelline exerts its neuroprotective effects in experimental spinal cord injury through modulation of inflammation, apoptosis, and neurotrophic factors
Published 2025-01-01“…Conclusions: Trigonelline shows neuroprotective properties in SCI rats by reducing allodynia, hyperalgesia, and inflammation, stabilizing mitochondrial enzyme complexes, and modulating apoptotic and neurotrophic factors. Thus, trigonelline holds promise as a potential neuroprotective agent.…”
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Taenia crassiceps-Excreted/Secreted Products Induce a Defined MicroRNA Profile that Modulates Inflammatory Properties of Macrophages
Published 2019-01-01“…Helminth parasites modulate immune responses in their host to prevent their elimination and to establish chronic infections. …”
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1069
How do agricultural polders modulate nutrient dynamics under extreme flooding: Insights for water management in lowland areas
Published 2025-02-01“…This study used field investigation and high-frequency monitoring to examine the nutrient dynamics modulated by agricultural polders in Lake Chaohu Basin, China when facing the extreme 2020 Yangtze River flood. …”
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1070
Research Advances in the Role of Cereal Dietary Fiber in Modulating Glucose and lipid Metabolism via the Gut Microbiota-Bile Acid
Published 2025-01-01“…Recent studies suggest that dietary fiber intake regulates glucose and lipid homeostasis by modulating bile acid metabolism. This process is closely associated with gut microbiota. …”
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Zingiber striolatum phytochemicals ameliorated hyperglycemia symptoms by modulating gut microbial communities in mice with type 2 diabetes mellitus
Published 2025-01-01“…Predictive analysis of the correlation between gut microbiota and hypoglycemic parameters identified Dubosiella, Bacillus, and Mailhella as potential microbial biomarkers for further investigation into the pathogenesis of T2DM.ConclusionZSE plays a pivotal role in mitigating hyperglycemia in T2DM mice through the modulation of intestinal microbiota communities.…”
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1076
GABAergic neurons in basal forebrain exert frequency-specific modulation on auditory cortex and enhance attentional selection of auditory stimuli
Published 2025-01-01“…We employed a detection task where rats detected a narrow band target embedded in broad band noise, while optogenetically modulating GABAergic BF activity. We found that GABAergic BF modulation impacted target detection specifically close to perceptual threshold, consistent with a role in attentional modulation. …”
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Application of Combustion Module Coupled with Cavity Ring-Down Spectroscopy for Simultaneous Measurement of SOC and δ13C-SOC
Published 2018-01-01“…The accuracy and utility of a combustion module coupled with cavity ring-down spectroscopy (CM-CRDS) system were assessed for simultaneously determining SOC and δ13C-SOC. …”
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5-Aminolevulinic acid activates the MdWRKY71-MdMADS1 module to enhance anthocyanin biosynthesis in apple
Published 2025-02-01Subjects: Get full text
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