Capsaicin Modulates Ruminal Fermentation and Bacterial Communities in Beef Cattle with High-Grain Diet-Induced Subacute Ruminal Acidosis by Wei You, Haijian Cheng, Xin Hu, Enliang Song, Fugui Jiang

“…In summary, these results suggest that dietary capsaicin supplementation can limit the adverse effects of SARA through the modulation of bacterial communities within the rumen, thus altering ruminal fermentation in beef cattle.…”
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Protocol for visualizing the chromatin assembly properties of epigenetic protein complexes via an HTM module-mediated artificial tethering system by Shanli Guan, Jiajia Tang, Cuixia Di, Bo Cheng

“…Here, we present a protocol utilizing heterochromatin-targeting module (HTM) module-mediated chromatin tethering followed by microscopy-based visualization to detect the recruitment priority between two components in Polycomb repressive complex 1 (PRC1). …”
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Hei-Gu-Teng Zhuifenghuoluo Granule Modulates IL-12 Signal Pathway to Inhibit the Inflammatory Response in Rheumatoid Arthritis by Kang Zheng, Zexu Chen, Wen Sun, Bin Liu, Danping Fan, Qingqing Guo, Hui Luo, Jiawen Shen, Li Li, Xiaojuan He, Shuang Kou, Xiaoya Li, Guoming Pang, Hongchuan Zhao, Cheng Lu

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Transcriptome-Based Modeling Reveals that Oxidative Stress Induces Modulation of the AtfA-Dependent Signaling Networks in Aspergillus nidulans by Erzsébet Orosz, Károly Antal, Zoltán Gazdag, Zsuzsa Szabó, Kap-Hoon Han, Jae-Hyuk Yu, István Pócsi, Tamás Emri

“…Our model suggests that an important function of AtfA is to modulate the transduction of stress signals. Although it may regulate directly only a limited number of genes, these include elements of the signaling network, for example, members of the two-component signal transduction systems. …”
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Cardioprotective effects of hUCMSCs-Exosi-EGR1 MN patch in MI/RI by modulating oxidative stress and mitophagy by Chen Huang, Xun Zhang, Shi-Xiong Wu, Qing Chang, Zhi-Kun Zheng, Jing Xu

“…Noteworthy outcomes from in vivo experiments included significant improvements in cardiac function, reduced cardiac fibrosis, and decreased apoptosis rates in MI/RI mice, emphasizing the potential therapeutic value of the Exosi-EGR1 MN patch in mitigating MI/RI through modulation of oxidative stress and mitophagy mechanisms.…”
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Anti-TNF-Mediated Modulation of Prohepcidin Improves Iron Availability in Inflammatory Bowel Disease, in an IL-6-Mediated Fashion by Flaminia Cavallaro, Lorena Duca, Laura Francesca Pisani, Roberta Rigolini, Luisa Spina, Gian Eugenio Tontini, Nadia Munizio, Elena Costa, Maria Domenica Cappellini, Maurizio Vecchi, Luca Pastorelli

“…This effect appears to be related to the modulation of the cytokine network and specifically IL-6 leading to a relevant decrease of hepcidin, a master regulator of ACD.…”
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Point of Common Coupling Voltage Modulated Direct Power Control of Grid-Tied Photovoltaic Inverter for AC Microgrid Application by Shameem Ahmad, Hamza Mubarak, Umme Kulsum Jhuma, Tofael Ahmed, Saad Mekhilef, Hazlie Mokhlis

“…The proposed PCC voltage modulated (PVM) theory-based DPC method (PVMT-DPC) is composed of nonlinear PVM, nonlinear damping, conventional feedforward, and feedback PI controllers. …”
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Multiscale Modeling Indicates That Temperature Dependent [Ca2+]i Spiking in Astrocytes Is Quantitatively Consistent with Modulated SERCA Activity by Niko Komin, Mahsa Moein, Mark H. Ellisman, Alexander Skupin

“…Changes in the cytosolic Ca2+ concentration ([Ca2+]i) are the most predominant active signaling mechanism in astrocytes that can modulate neuronal activity and is assumed to influence neuronal plasticity. …”
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Enhanced Optical Modulation Properties via Two-step Annealing of Sol–Gel Deposited Vanadium Dioxide Thin Films by Zhencheng Li, Jiacheng Yu, Yongde Xia, Zhuxian Yang, Yunbin He, Nannan Wang, Yanqiu Zhu

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Theaflavin Ameliorates Cerebral Ischemia-Reperfusion Injury in Rats Through Its Anti-Inflammatory Effect and Modulation of STAT-1 by Fei Cai, Cai-Rong Li, Ji-Liang Wu, Jian-Guo Chen, Chao Liu, Qing Min, Wei Yu, Chang-Han Ouyang, Jin-He Chen

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Insulin Modulates Paracoccidioides brasiliensis-Induced Inflammation by Restoring the Populations of NK Cells, Dendritic Cells, and B Lymphocytes in Lungs by Felipe Beccaria Casagrande, Sabrina de Souza Ferreira, Fernanda Peixoto Barbosa Nunes, Lavínia Maria Dal’Mas Romera, Suelen Silvana dos Santos, Fernando Henrique Galvão Tessaro, Paula Regina Knox de Souza, Sandro Rogério Almeida, Joilson Oliveira Martins

“…The data suggest that diabetic mice present impaired immunological response to Pb18 infection and insulin modulates inflammation by reducing IL-6 levels in lung and CINC-1 levels in spleen and liver homogenates, restoring leukocyte concentrations in PeLF and also restoring populations of dendritic cells and B lymphocytes in lungs of diabetic mice, permitting the host to better control the infection.…”
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Investigation of Novel Aronia Bioactive Fraction-Alginic Acid Nanocomplex on the Enhanced Modulation of Neuroinflammation and Inhibition of Aβ Aggregation by Bong-Keun Jang, Soo Jung Shin, Hyun Ha Park, Vijay Kumar, Yong Ho Park, Jeom-Yong Kim, Hye-Yeon Kang, Sunyoung Park, Youngsun Kwon, Sang-Eun Shin, Minho Moon, Beom-Jin Lee

“…Conclusions: Our data indicate that AANCPs are more stable than ABFs and effective for cognitive disorders and neuroinflammation via modulation of M2 microglial polarization.…”
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Expressive Art Therapy Psychoeducation Module for Mental Health, Resilience, Attitude Towards Seeking Counselling Among Trainee Teachers by Siti NurulHida Abdul Rahman, Mohd Izwan Mahmud, Ku Suhaila Ku Johari, Salleh Amat

Subjects: “…Psychoeducational module , Expressive Art Therapy, Teacher Trainee.…”
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Sodium alginate ameliorates health in freshwater fish through gut-liver axis modulation under high carbohydrate diets by Wenlu Zhu, Huilin Zhang, Haitao Pan, Hao Zeng, Wenjun Wang, Yunfeng Liu, Zirui Wang, Qiubai Zhou, Chuanqi Yu

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Wedelolactone Mitigates Alcoholic Steatohepatitis via Modulating the TLR4/MyD88/NF-κB Pathway by Tao Jiang, Bingde Hu, Yongxia Li, Shuihong Yu

“…WEL may mitigate the impact of ASH by modulating the TLR4/MyD88/NF-κB pathway.…”
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Gut Microbiome Modulation in Hepatocellular Carcinoma: Preventive Role in NAFLD/NASH Progression and Potential Applications in Immunotherapy-Based Strategies by Elisa Monti, Clara Vianello, Ilaria Leoni, Giuseppe Galvani, Annalisa Lippolis, Federica D’Amico, Sara Roggiani, Claudio Stefanelli, Silvia Turroni, Francesca Fornari

“…We also describe encouraging preclinical findings on the modulation of GM to improve liver functions in CLD, boost the antitumor immune response (e.g., probiotic supplementations or anti-hypercholesterolemic drug treatment), and ultimately delay NAFLD progression to HCC. …”
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Circular RNA circBNC2 inhibits tumorigenesis by modulating ferroptosis and acts as a nanotherapeutic target in prostate cancer by Xiang Pan, Kailai Chen, Wei Gao, Meiqi Xu, Fanlong Meng, Mengyuan Wu, Zi Qi Wang, Yun Qi Li, Wanhai Xu, Manjie Zhang, Yakun Luo

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Engineering a halloysite nanotube-enhanced hydrogel 3D skin model for modulated inflammation and accelerated wound healing by Rui Xu, Xihong Fu, Lerong Lun, Wenjing Jiang, Xuemei Situ, Xiaobao Huang, Ying Xiong, Chun Liu, Fang Wang

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Modulation of the thiol redox proteome by sugarcane ash-derived silica nanoparticles: insights into chronic kidney disease of unknown etiology by Arthur D. Stem, Cole R. Michel, Peter S. Harris, Keegan L. Rogers, Matthew Gibb, Carlos A. Roncal-Jimenez, Richard Reisdorph, Richard J. Johnson, James R. Roede, Kristofer S. Fritz, Jared M. Brown

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Modulation of High-Frequency rTMS on Reward Circuitry in Individuals with Nicotine Dependence: A Preliminary fMRI Study by Tao Wang, Ruiyang Li, Dongyan Chen, Mei Xie, Zhiqiang Li, Huan Mao, Yuting Ling, Xiaoyun Liang, Guojun Xu, Jianjun Zhang

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