Harnessing the power of proteins in modulation of miRNAs for targeting Iron deficiency Anemia: Opinion for future implications and strategies by Ray Wagiu Basrowi, Ray Wagiu Basrowi, Ray Wagiu Basrowi, Tonny Sundjaya, Tonny Sundjaya, Dessy Pratiwi, Nurlinah Amalia, Nurlinah Amalia, Nurlinah Amalia, Yosi Yohanes Putra Tandi, Muhammad Yasir Syafa’atulloh, Garuda Nusantara Putra Utomo, Muhammad Abdir Rahman Albarok, Fahrul Nurkolis

“…These miRNA-protein interactions suggest targeted therapies such as protein-based miRNA modulators could optimize erythropoiesis, advancing IDA management. …”
Get full text

MicroRNA-155 modulates methotrexate-induced spatial memory impairment by disruption of the blood-brain barrier integrity by Yu-Chieh Chen, Li-Tung Huang, Hong-Ren Yu, Jiunn-Ming Sheen

Get full text

Evaluation method and module design for cost-effective compliance with irradiance guidelines to maintain soil quality in solar parks by Cesar Ilkay, Van Aken Bas B.

Subjects: Get full text

Correction to: Natural compounds modulate the mechanism of action of tumour-associated macrophages against colorectal cancer: a review by Weichen Yuan, Jiexiang Zhang, Haibin Chen, Yupei Zhuang, Hongli Zhou, Wenting Li, Wenli Qiu, Hongguang Zhou

Get full text

A chemical genetic screen with the EXO70 inhibitor Endosidin2 uncovers potential modulators of exocytosis in Arabidopsis by Xiaohui Li, Diwen Wang, Xianglin Yin, Mingji Dai, Christopher J. Staiger, Chunhua Zhang

“…Despite some understanding of molecular and cellular aspects of exocyst function obtained through reverse genetics and direct interaction assays, knowledge about upstream modulators and genetic interactors remains limited. …”
Get full text

Glucocorticoid-Induced TNFR-Related (GITR) Protein and Its Ligand in Antitumor Immunity: Functional Role and Therapeutic Modulation by Theresa Placke, Hans-Georg Kopp, Helmut Rainer Salih

“…The ability of the tumor necrosis factor receptor (TNFR) family member GITR to modulate immune responses has been the subject of multiple studies. …”
Get full text

The cholesterol metabolite 25-hydroxycholesterol suppresses porcine deltacoronavirus via lipophagy inhibition and mTORC1 modulation by Jia-lu Zhang, Xue-fei Wang, Jia-lin Li, Cong Duan, Jiu-feng Wang

Get full text

The Antiseptic Octenidine Inhibits Langerhans Cell Activation and Modulates Cytokine Expression upon Superficial Wounding with Tape Stripping by Nenad Nikolić, Philip Kienzl, Pooja Tajpara, Martin Vierhapper, Johannes Matiasek, Adelheid Elbe-Bürger

Get full text

Higher performance enhancement of direct torque control by using Space Vector Modulation for doubly fed induction machine by Gouaamar Radouan, El Fadl Adiba, Bri Seddik, Mekrini Zineb

Subjects: Get full text

Differential Effects of Alcoholic and Non-Alcoholic Beer Intake on Renin–Angiotensin System Modulation in Spontaneous Hypertensive Rats by María Dolores Mayas, Cristina Cueto-Ureña, María Jesús Ramírez-Expósito, José Manuel Martínez-Martos

“…Moderate beer consumption did not elevate blood pressure in WKY or SHRs. Nevertheless, beer modulated RAS-regulating enzyme activities, indicating potential impacts on cardiovascular homeostasis.…”
Get full text

Anticancer Drug-Induced Apoptosis and Cytotoxicity in Prostate Cancer Cells Are Modulated by Organ-Specific Stromal Cell Factors by Bal L. Lokeshwar, Kamalaveni R. Prabhakar, Tie Yan Shang, Zafiria Mourelatos, De-Quan Li

Get full text

Size-controllable synthesis of hydroxyapatite nanorods via fluorine modulation: applications in dental adhesives for enhanced enamel remineralization by Linzhi Meng, Mengmeng Shu, Peng Mei, Yakun Liang, Lunguo Xia

Get full text

Temperature and repeated catecholamine surges modulate regional wall motion abnormalities in a rodent takotsubo syndrome model by Ermir Zulfaj, AmirAli Nejat, Abdulhussain Haamid, Aaron Espinosa, Ahmed Elmahdy, Tetiana Pylova, Sandeep Jha, Björn Redfors, Elmir Omerovic

Get full text

Improved Switching Strategy for Selective Harmonic Elimination in DC-AC Signal Generation via Pulse-Width Modulation by Francisco Palacios-Quiñonero, Jesus Vicente-Rodrigo, Maria A. Molina-Hernández, Hamid Reza Karimi

“…We present an advanced design methodology for pulse-width-modulated (PWM) DC-AC signal generation. Using design methods based on the Walsh transform, AC sinusoidal signals can be approximated by suitable PWM signals. …”
Get full text

Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells by Yoon Kyung Jeon, Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

“…Furthermore, IHC staining of human tumor tissues revealed that MITF+ MO-MDSCs are more frequently observed in tumor tissues than in tumor-free draining lymph nodes obtained from patients with cancer.Conclusions Our results indicate that MITF regulates the differentiation and function of MDSCs and can be a novel therapeutic target for modulating MDSC activity in immunosuppressive TMEs.…”
Get full text

Enhancing zero-shot relation extraction with a dual contrastive learning framework and a cross-attention module by Diyou Li, Lijuan Zhang, Jie Huang, Neal Xiong, Lei Zhang, Jian Wan

“…Thus, this paper proposes a dual contrastive learning framework and a cross-attention network module for ZSRE. First, our model designs a dual contrastive learning framework to compare the input sentences and relation descriptions from different perspectives; this process aims to achieve better separation between different relation categories in the representation space. …”
Get full text

Novel Mechanisms Modulating Palmitate-Induced Inflammatory Factors in Hypertrophied 3T3-L1 Adipocytes by AMPK by Naru Morita, Toshio Hosaka, Atsuko Kitahara, Toshitaka Murashima, Hirohisa Onuma, Yoshikazu Sumitani, Kazuto Takahashi, Toshiaki Tanaka, Takuma Kondo, Hitoshi Ishida

Get full text

Human Cardiac Fibroblast Number and Activation State Modulate Electromechanical Function of hiPSC-Cardiomyocytes in Engineered Myocardium by Cassady E. Rupert, Tae Yun Kim, Bum-Rak Choi, Kareen L. K. Coulombe

“…Taken together, the results of this study demonstrate that human cardiac fibroblast number and activation state modulate electromechanical function of hiPSC-cardiomyocytes and that a low percentage of quiescent hCFs are a valuable cell source to advance a healthy electromechanical response of engineered cardiac tissue for regenerative medicine applications.…”
Get full text

Acupuncture Modulates Disrupted Whole-Brain Network after Ischemic Stroke: Evidence Based on Graph Theory Analysis by Xiao Han, He Jin, Kuangshi Li, Yanzhe Ning, Lan Jiang, Pei Chen, Hongwei Liu, Yong Zhang, Hua Zhang, Zhongjian Tan, Fangyuan Cui, Yi Ren, Lijun Bai, Yihuai Zou

“…Stroke can lead to disruption of the whole-brain network in patients. Acupuncture can modulate the functional network on a large-scale level in healthy individuals. …”
Get full text

Novel anti-inflammatory properties of mannose oligosaccharides in the treatment of inflammatory bowel disease via LGALS3 modulation by Yaqi Du, Yan Fan, Xin Li, Fenqin Chen

“…Abstract This study investigates the role of Gum Arabic Mannose Oligosaccharides (GA-MOS) in modulating gut microbiota and alleviating symptoms of Inflammatory Bowel Disease (IBD). …”
Get full text