Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice by Shiyue Sun, Tongtong Yu, Joo Young Huh, Yujie Cai, Somy Yoon, Hafiz Muhammad Ahmad Javaid

“…Mechanistically, AGH modulated the AKT/FOXO1 pathway, decreasing myogenin and Foxo1 while increasing MyoD. …”
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The Campylobacter jejuni BumS sensor phosphatase detects the branched short-chain fatty acids isobutyrate and isovalerate as direct cues for signal transduction by Nestor Ruiz, Jiawei Xing, Igor B. Zhulin, Chad A. Brautigam, David R. Hendrixson

“…In this work, we expanded the repertoire of lower intestinal metabolites that are cues sensed by BumS that modulate the expression of genes required for colonization to include the branched short-chain fatty acids isobutyrate and isovalerate. …”
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Impact of Amarogentin on Gastric Carcinoma Cell Multiplication, Apoptosis and Migration via circKIF4A/miR-152-3p by Zhi Tan, Weining Wang, Jin Peng, Zhen Zhou, Jia Pan, Aiming Peng, Hui Cao, Wenling Fan

“…AG can decrease GC multiplication, clone formation and migration and induce apoptosis via modulating circKIF4A/miR-152-3p expression.…”
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Distinct dynamic regulation of pectoralis muscle metabolomics by insulin and the promotion of glucose-lipid metabolism with extended duration by Xiangli Zhang, Pengfei Du, Ziyang Wang, Yao Zhu, Xuemeng Si, Wen Chen, Yanqun Huang

“…Metabolomic analysis revealed that insulin promotes the downregulation of 63 out of 71 metabolites at 15 min and the upregulation of 101 out of 134 metabolites at 120 min, mainly associated with lysine degradation and thyroid hormone signaling pathways, respectively. 7 metabolites were dynamically modulated in the same manner over time (2 up-up and 5 down-down). …”
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Effects and function of citric acid on fermentation quality and microbial community in sugarcane tops silage with high and low water-soluble carbohydrate content by Qichao Gu, Jie Zhang, Bo Lin, Hao Ding, Qi Yan, Caixiang Wei, Yipei Yao, Ruizhanghui Wang, Caixia Zou

“…In conclusion, CA inoculation could be effective in decreasing nutrients loss, improving fermentation quality, inhibiting harmful microorganisms, and modulating the metabolic pathways of microorganisms in STS with high and low WSC contents prior to and after aerobic exposure.…”
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Lutein and inflammation: a comprehensive review of its mechanisms of action by Paradentavida Prathyusha, Geetha Viswanathan, Anjilikal Tomy Tomcy, Ponnamparambil P. Binitha, Smitha V. Bava, Edakkadath R. Sindhu

“…Lutein protects against alcohol-induced liver damage by modulating the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling pathway. …”
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Inclusive educational process at the university: Theoretical and experimental model of teachers' psychological readiness by V. Z. Kantor, Yu. L. Proekt

“…For statistical calculations, the program IBM SPSS Statistics ver.23 and the AMOS module were used. Results. The integrative model of the psychological readiness of faculty for the implementation of an inclusive educational process has been theoretically substantiated and experimentally confirmed. …”
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ERK1/2 Inhibition Alleviates Diabetic Cardiomyopathy by Suppressing Fatty Acid Metabolism by Erin McLean, Caroline De Roo, Annabel Maag, Megan Coble, Jefferson Cano, Ruijie Liu

“…Conclusion: ERK1/2 are potential therapeutic targets for diabetic cardiomyopathy by modulating fatty acid metabolism in the heart.…”
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Les quais nos 1, 12 et 13 du port romain de Saint-Lupien à Rezé/Ratiatum (Loire-Atlantique) by Xavier Favreau, Nicolas Ménez

“…The bank of the Loire was thus punctuated, and then divided into several construction modules built according to timber box construction guidelines and serving as docks. …”
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Mechanistic insights into chloride‐related heart failure progression according to the plasma volume status by Hajime Kataoka

“…Conclusions According to the changes in the ePVS, HF progression may result from a difference between two HF types (i.e. increased vs. non‐increased serum chloride concentration) in the cardiac reserve in response to a given cardiac burden by modulating plasma volume status via the possible tonicity potential of chloride.…”
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Incidence Rate of Type 2 Diabetes Mellitus after Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of 170,139 Women by Zhuyu Li, Yunjiu Cheng, Dongyu Wang, Haitian Chen, Hanqing Chen, Wai-kit Ming, Zilian Wang

“…The purpose of this meta-analysis was to define the incidence rate of T2DM among women with a history of GDM and to examine what might modulate the rate. Research Design and Methods. We searched PubMed and Embase for terms related to T2DM after GDM up to January 2019. …”
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A mobile-based multidomain lifestyle intervention using Cognitive Evergreenland for older adults with subjective cognitive decline: a feasibility study by Rong Lin, Yuanjiao Yan, Zhili Chen, Chenshan Huang, Junyu Zhao, Mingfeng Chen, Hong Li

“…In terms of average usage, cognitive training emerged as the most frequently used functional module (95.73%), closely followed by health education (95.02%). …”
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Big Earth data processing using machine learning for integrated mapping of the dead sea fault, Jordan by Polina Lemenkova

“…The research presents an extended description in methodology, including the explanations of code snippets from the GMT modules and examples of the use of R libraries ‘raster’ and ‘tmap’. …”
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Determining the impact of mobile-based self-care applications on reducing anxiety in healthcare providers: a systematic review by Mohammad Mahdi Askarizadeh, Leila Gholamhosseini, Reza Khajouei, Saeedeh Homayee, Fatemeh Askarizadeh, Leila Ahmadian

“…We used this form to collect data including the author’s name, publication year, country, study type, intervention duration, study objectives, platform used, Modules presented in technologies, Methods of reducing anxiety, questionnaire details, and Effectiveness assessment. …”
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The Association of moisture intake and constipation among us adults: evidence from NHANES 2005–2010 by Deng-Chao Wang, Xue-Feng Peng, Wen-Xing Chen, Miao Yu

“…RCS regression revealed a significant non-linear negative relationship between moisture intake and constipation prevalence (P < 0.001). Depression may modulate the relationship between moisture and constipation (interaction effect P = 0.014). …”
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Identification and validation of prognostic biomarkers in ccRCC: immune-stromal score and survival prediction by Fang Lyu, Yuxin Zhong, Qingliu He, Wen Xiao, Xiaoping Zhang

“…The weighted gene co-expression network analysis (WGCNA) was employed to identify gene modules associated with these scores. Differentially expressed genes were assessed using the limma package. …”
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Efficacy of Curcumin on Treating Cancer Anorexia-Cachexia Syndrome in Locally or Advanced Head and Neck Cancer: A Double-Blind, Placebo-Controlled Randomised Phase IIa Trial (CurCh... by Tawasapon Thambamroong, Kasan Seetalarom, Siriwimon Saichaemchan, Yanisa Pumsutas, Naiyarat Prasongsook

“…Curcumin shows anti-inflammatory effects, including modulated CAS in animal and in vitro studies. Objective. …”
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Signalisation multimodale de la gestation chez le macaque japonais (Macaca fuscata) by Cécile Garcia, Lucie Rigaill, Andrew JJ. MacIntosh, James P. Higham, Sandra Winters, Keiko Shimizu, Keiko Mouri, Takeshi Furuichi

“…Cependant, l’expression de signaux relatifs à la gestation et la façon dont ces signaux peuvent moduler les décisions d’accouplement post-conception des mâles sont encore peu comprises. …”
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Effects of a social participation-focused virtual reality intervention for community-dwelling stroke survivors with physical disabilities: a randomised controlled trial protocol by Janita Pak Chun Chau, Suzanne Hoi Shan Lo, Vivian Wing Yan Lee, Kai Chow Choi, Alexander Yuk Lun Lau, David R Thompson, Eddie Chi Fai Kwok

“…The intervention group will receive a newly developed 6-week novel custom-made SP-VR application comprising two sessions weekly. Three SP-VR modules will cover key aspects of survivors’ social health needs, namely functional rehabilitation, social participation, and social interaction and recreation. …”
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Projet Sphinx : réhabilitation d'un groupe de mandrills en milieu naturel by Lucille Martin‑Klimoczko, Anais Herbert, Anne Meyer, Mélanie Harté

“…Le groupe formé a été placé dans une volière d’habituation durant une période d’un mois et demi, puis des colliers radio-émetteurs ont été placés sur 4 femelles.Au terme de cette période, les mandrills ont été transférés au Parc de la Lékédi et relâchés au sein d’un module vaste de 11 000 hectares de forêt et de savanes.Un suivi quotidien des mandrills avec un maintien du nourrissage a été réalisé durant les trois premiers mois suivant le relâché. …”
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