Identification and Immunological Characterization of Cuproptosis Related Genes in Preeclampsia Using Bioinformatics Analysis and Machine Learning by Tiantian Yu, Guiying Wang, Xia Xu, Jianying Yan

“…Additionally, the application of Weighted Gene Co‐expression Network Analysis (WGCNA) was utilized to differentiate modules consisting of co‐expressed genes and conduct clustering analysis. …”
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Role of outer membrane vesicles of hypervirulent Klebsiella pneumoniae isolated from bovine uterine discharge in pro-inflammatory dysregulation by A. F. Daham, A. H. Jaber, A. Neamah, H. Al-Karagoly

“…This ability of hvKP OMVs to evade the immune system and modulate host responses contributes significantly to the bacterium’s pathogenicity.…”

Evaluation of Blood Culture Results in Patients with Malignancy in Erzurum Province, Turkey by Osman Aktas, Ozgür Akbaba, Muhammet Hamidullah Uyanik, Hakan Uslu

“…The hospital information management system modules were used to acquire patient data and blood culture results.Results: Various microorganisms grew in 10.1% of blood cultures. …”
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Evaluation of Safety and Efficacy of a Single Lorecivivint Injection in Patients with Knee Osteoarthritis: A Multicenter, Observational Extension Trial by Christopher J. Swearingen, Jeyanesh R. S. Tambiah, Ismail Simsek, Heli Ghandehari, Sarah Kennedy, Yusuf Yazici

“…Abstract Introduction Lorecivivint (LOR), a CDC-like kinase/dual-specificity tyrosine kinase (CLK/DYRK) inhibitor thought to modulate inflammatory and Wnt pathways, is being developed as a potential intra-articular knee osteoarthritis (OA) treatment. …”
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A longitudinal study of the association between the outcome of bariatric surgery and mental health indicators in Chinese patients: an examination of the interaction effect by Hung-Yen Lin, Te-Chang Changchien, Tsung-Jen Hsieh, Cheng-Sheng Chen, Yung-Chieh Yen

“…Despite the improvements in physical and mental health post-surgery, the findings indicate that the impact of depression on effectiveness of bariatric surgery is modulated by the time elapsed since the surgery, emphasizing the importance of ongoing mental health care for these patients. …”
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Efficacy and Safety of Ergoferon in Children from 6 Months to 6 Years Old with Acute Respiratory Viral Infections in Contemporary Outpatient Practice: A Multicenter, Double-Blind,... by N. A. Geppe, B. M. Blokhin, O. V. Shamsheva, S. T. Abdrakhmanova, K. A. Alikhanova, G. T. Myrzabekova

“…Derived by technological treatment of antibodies to interferon gamma, histamine, and CD4, Ergoferon was previously proved to modulate its molecular targets promoting effective antiviral protection. …”
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IL-13 Augments Histone Demethylase JMJD2B/KDM4B Expression Levels, Activity, and Nuclear Translocation in Airway Fibroblasts in Asthma by Khuloud Bajbouj, Mahmood Y. Hachim, Rakhee K. Ramakrishnan, Huwaida Fazel, Jumana Mustafa, Shahed Alzaghari, Mahmoud Eladl, Jasmin Shafarin, Ronald Olivenstein, Qutayba Hamid

“…Bioinformatic analysis revealed the differential expression of the histone demethylase JMJD2B/KDM4B, a well-known epigenetic modulator that leads to the demethylation of different lysine residues on histones, in IL-13-treated lung fibroblasts. …”
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Shenmai injection revives cardiac function in rats with hypertensive heart failure: involvement of microbial-host co-metabolism by Lin Li, Senjie Zhong, Jiahao Ye, Siyuan Hu, Xiajun Xiong, Guangyu Chen, Zhixi Hu

“…In conclusion, this study highlights the effectiveness of SMI in alleviating H-HF and its potential to modulate microbial-host co-metabolism. Through a comprehensive discussion of the interconnected relationships among the components, targets, metabolites, and gut microbiota, it provided fresh light on the therapeutic mechanism of SMI on H-HF.…”
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Potential biomarkers and immune infiltration linking endometriosis with recurrent pregnancy loss based on bioinformatics and machine learning by Jianhui Chen, Qun Li, Xiaofang Liu, Fang Lin, Yaling Jing, Jiayan Yang, Lianfang Zhao

“…This study aims to investigate the potential biomarkers and immune infiltration in EMs and RPL, providing a basis for early detection and treatment of the two diseases.MethodsTwo RPL and six EMs transcriptomic datasets from the Gene Expression Omnibus (GEO) database were used for differential analysis via limma package, followed by weighted gene co-expression network analysis (WGCNA) for key modules screening. Protein-protein interaction (PPI) network and two machine learning algorithms were applied to identify the common core genes in both diseases. …”
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Increasing Safety of Vulnerable Road Users in Scenarios With Occlusion: A Collaborative Approach for Smart Infrastructures and Automated Vehicles by Thiago de Borba, Ondrej Vaculin, Hormoz Marzbani, Reza Nakhaie Jazar

“…The proposed extended perception system comprises four main modules: traffic monitoring, long-term motion prediction, collision risk assessment, and trajectory planning. …”
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Adaptive Neuro-Fuzzy Inference System guided objective function parameter optimization for inverse treatment planning by Eduardo Cisternas Jiménez, Fang-Fang Yin, Fang-Fang Yin, Fang-Fang Yin

“…Intensity-Modulated Radiation Therapy requires the manual adjustment to numerous treatment plan parameters (TPPs) through a trial-and-error process to deliver precise radiation doses to the target while minimizing exposure to surrounding healthy tissues. …”
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Guanxinning Tablet Attenuates Coronary Atherosclerosis via Regulating the Gut Microbiota and Their Metabolites in Tibetan Minipigs Induced by a High-Fat Diet by Qinqin Yang, Yanyun Xu, Liye Shen, Yongming Pan, Junjie Huang, Quanxin Ma, Chen Yu, Jiaojiao Chen, Yu Chen, Minli Chen

“…In sum, the results showed that GXNT had a satisfactory anti-CA effect, and the mechanism was closely associated with modulating gut microbiota and related metabolites.…”
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Siphon-type hydroelectric plants: application for power generation in a low head dam in southern Brazil by Janaina Terhorst Pizutti, Carlos Henrique Pereira Assunção Galdino, Fernando Setembrino Cruz Meirelles, Alexandre Beluco

“…Among the simulations performed, the most promising optimal solution was hybrid, considering among its components a set of siphon turbines totaling 271 kW, plus 50 kW in photovoltaic modules and 140 kW in a diesel support system. A battery bank with 32 200 Ah batteries complemented this system. …”
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WNT3A promotes the cementogenic differentiation of dental pulp stem cells through the FOXO1 signaling pathway by Dongmei Cheng, Yang Bao, Xue Wang, Haidong Xiang, Tianyuan Guo, Yong Du, Zhiyong Zhang, Han Guo

“…Weighted gene co-expression network analysis (WGCNA) was employed to identify significant modules. Pathway enrichment exploration was conducted utilizing gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Set Enrichment Analysis (GSEA), and Metascape tools. …”
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Total Glucosides of Paeony Alleviate Cell Apoptosis and Inflammation by Targeting the Long Noncoding RNA XIST/MicroRNA-124-3p/ITGB1 Axis in Renal Ischemia/Reperfusion Injury by Fang Chen, Yi Hu, Yuetao Xie, Zonghui Zhao, Lin Ma, Zhili Li, Wanlong Tan

“…In vitro, TGP inhibited XIST expression to modulate the miR-124-3p/ITGB1 axis, alleviating the apoptosis and inflammation of H/R-treated renal cells.…”
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Association of TCF7L2 genetic variants rs12255372 and rs7903146 with the polycystic ovary syndrome risk: systematic review and meta-analysis by Idrees A. Shah, Rabiya Rashid, Haroon Rashid, Abid Bhat, Mohd Ashraf Ganie

“…Conclusion Unlike T2DM, our results showed that rs7903146 and rs12255372 variants of the TCF7L2 gene do not modulate the PCOS risk. However, the role of other TCF7L2 variants remains to be studied in future studies.…”
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Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications by Pharaoh Fellow Mwale, Cheng-Ta Hsieh, Ting-Lin Yen, Jing-Shiun Jan, Rajeev Taliyan, Chih-Hao Yang, Wen-Bin Yang

“…As a key regulator of neuroinflammation, CHI3L1 modulates microglia and astrocyte activity, driving the release of proinflammatory cytokines that exacerbate disease progression. …”
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The Potential of SHAP and Machine Learning for Personalized Explanations of Influencing Factors in Myopic Treatment for Children by Jun-Wei Chen, Hsin-An Chen, Tzu-Chi Liu, Tzu-En Wu, Chi-Jie Lu

“…Then, the best-performing model was further interpreted using SHAP values. The SHAP module created a personalized and dynamic graphic to illustrate how various factors (e.g., age, sex, cumulative duration, and dosage of atropine treatment) affect the end IOP. …”
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Ghanaian women’s experience of intimate partner violence (IPV) during group antenatal care: a brief report from a cluster randomised controlled trial by Samia J. Abdelnabi, Michelle L. Munro-Kramer, Cheryl A. Moyer, John E.O. Williams, Jody R. Lori

“…The purpose was to understand the effect of a healthy relationship Group ANC module on experiences of IPV and safety planning as well as to explore the relationship between self-efficacy on the experiences of IPV and safety planning. …”
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LDWLE: self-supervised driven low-light object detection framework by Xiaoyang shen, Haibin Li, Yaqian Li, Wenming Zhang

“…If the input image is normally lit, it first passes through a low-light image conversion module to be transformed into a low-light image before being fed into the encoder. …”
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