MicroRNA-26b inhibits cardiac remodeling after myocardial infarction by targeting ring finger protein 6 expression by Chun-Mei Tang, Qiang Su, Hai-Xia Zhao, He-Huan Sui, Jing Liang, Li-Sha Zhu, Si-Yun Yang, Tao Liu

“…We also found that the miR-26b mimic could negatively modulate RNF6 expression to inactivate the ERα/Bcl-xL axis. …”
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Synergistic toxicity of nanoplastics and Helicobacter pylori on digestive system in mice by Xiaolin Zhang, Yunqing Wang, Xiaohan Tong, Boqing Li, Sisi Liu, Yingzi Cui, Wenke Wang, Zhiqin Li, Chunlei Ma, Ying Zhang

“…These results indicate that co-exposure exacerbates tissue damage, inflammation, oxidative stress, and metabolic disruptions while modulating nanoparticle accumulation. These findings highlight the synergistic toxic effects of nanoplastics and H. pylori, underscoring the importance of understanding combined exposure risks for public health.…”
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Decoding oral cancer: insights from miRNA expression profiles and their regulatory targets by Xin Wang, Xin Wang, Shuang Zhang, Shuang Zhang, Shuyi Wang, Tao Cao, Tao Cao, Hong Fan, Hong Fan

“…MicroRNAs (miRNAs), as critical regulators of gene expression, have emerged as key players in modulating plethora of cellular mechanisms. This study analyzed miRNA and gene expression profiles in OC using publicly available datasets from the Gene Expression Omnibus (GEO) to explore their roles in tumorigenesis. …”
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Exploring seasonal dynamics of sea spray aerosol bioactivity: Insights into molecular effects on human bronchial epithelial cells by Zixia Liu, Emmanuel Van Acker, Maarten De Rijcke, Filip Van Nieuwerburgh, Colin Janssen, Jana Asselman

“…Our results suggest that SSA contains bioactive compounds that may originate from marine algae and modulate cellular processes related to human health. …”
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Drought-induced shifts in gross primary production pathways in Moso bamboo forests: Insights from improved BIOME-BGC and structural equation modeling by Zhaodong Zheng, Fangjie Mao, Huaqiang Du, Xuejian Li, Fengfeng Ye, Xianfeng Teng, Ningxin Yang, Jiacong Yu, Meixuan Song, Yinyin Zhao

“…In this study, photosynthetic water stress module of BIOME-BGC was improved and optimized by long-term carbon flux observations from the Anji MBF site, then the temporal variations of Gross Primary Production (GPP) were simulated and analyzed from 2000 to 2019. …”
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The Effects of Immunosuppressive Factors on Primary Dendritic Cells from C57BL/6 and CBA Mice by Vasiliy V. Kurilin, Julia N. Khantakova, Valeriy P. Tereschenko, Julia A. Lopatnikova, Irina A. Obleukhova, Sergey V. Sennikov

“…Dendritic cells (DCs) control immune responses by modulating T and B cells towards effector or tolerogenic responses. …”
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Glucose‐induced LINC01419 reprograms the glycolytic pathway by recruiting YBX1 to enhance PDK1 mRNA stability in hepatocellular carcinoma by Yanfang Liu, Junjiao Song, Qili Shi, Bing Chen, Wenying Qiu, Yizhe Liu, Shenglin Huang, Xianghuo He

“…The mechanism and therapeutic potential of cancer‐specific lncRNAs in modulating tumour glucose metabolism warrant in‐depth exploration. …”
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Survey of the risk behaviors and mental health of adolescents in Gabon by Joel Fleury Djoba Siawaya, Steeve Minto’o Rogombe, Mah Diawara, Rotimi Myrabelle Avome Houechenou, Nora Sylvana Efire Emagha, Zena Andrews, Lydie Armelle Moukambi, Anicet Christel Maloupazoa Siawaya, Amandine Mveang Nzoghe, Ofilia Mvoundza Ndjindji, Patrick Douada Mouguiama

“…Methods This study was done in 2021 and followed the Global School-Based Student Health Survey (GSHS) guidelines. Six core modules (alcohol, tobacco, and drug use, sexual behaviors, mental health, and safety) were included. …”
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Menthone lowers H3K27ac levels to inhibit Fusarium proliferatum growth by Li-Yan Zhang, Tian-Tian Li, Hong-Xin Liao, Jin-Rui Wen, Hong-Yan Nie, Fu-Rong Xu, Xiao-Yun Liu, Xian Dong

“…Histone acetylation is pivotal in modulating gene expression and influences biological processes in living organisms.ResultsThis study demonstrated that menthone, the primary component of Mentha haplocalyx EO, exhibited notable antifungal activity against Fusarium proliferatum (EC50 = 6.099 mmol/L). …”
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Image depth estimation assisted by multi-view projection by Liman Liu, Jinshan Tian, Guansheng Luo, Siyuan Xu, Chen Zhang, Huaifei Hu, Wenbing Tao

“…In addition, a long-distance attention decoding module is proposed to achieve effective extraction and aggregation of features in distant areas of the scene, which enhances the perception capability for outdoor long-distance. …”
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Universal conditional networks (UniCoN) for multi-age embryonic cartilage segmentation with Sparsely annotated data by Nishchal Sapkota, Yejia Zhang, Zihao Zhao, Maria Jose Gomez, Yuhan Hsi, Jordan A. Wilson, Kazuhiko Kawasaki, Greg Holmes, Meng Wu, Ethylin Wang Jabs, Joan T. Richtsmeier, Susan M. Motch Perrine, Danny Z. Chen

“…Extensive experiments on multi-age cartilage segmentation datasets show significant and consistent performance improvements when integrating our conditional modules into popular DL segmentation architectures. …”
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Anti-IL-5 treatment, but not neutrophil interference, attenuates inflammation in a mixed granulocytic asthma mouse model, elicited by air pollution by Joyceline De Volder, Annelies Bontinck, Valerie Haelterman, Louis Boon, Guy F. Joos, Guy G. Brusselle, Tania Maes

“…Moreover, we aimed to unravel whether neutrophils modulate the DEP-aggravated eosinophilic airway inflammation. …”
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Saussurea costus alleviates ulcerative colitis by regulating the gut microbiota and improving intestinal barrier integrity by Wen-lin Pang, Wen-lin Pang, Tian-gang Li, Tian-gang Li, Yin-ying Wang, Yin-ying Wang, Li-yun Song, Li-yun Song, Li Li, Li Li, Xiao-ya Li, Xiao-ya Li, Yong Qiu, Yong Qiu, Zhong-shan Yang, Zhong-shan Yang

“…In addition, analysis of 16S rRNA gene sequencing indicated that SC reduced harmful bacterial populations, such as Proteobacteria, while simultaneously enhancing the levels of beneficial bacteria like Lactobacillus, thereby contributing to the improvement of UC pathology.ConclusionThis study highlights the therapeutic potential of SC in managing UC through its ability to attenuate inflammatory responses, restore intestinal barrier functionality, and modulate gut microbiota composition, which findings offer insights into potential strategies for advancing UC treatment.…”
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State of intracardiac and central hemodynamics in patients with mitral valve insufficiency during surgery with cardioprotection by electrical fibrillation and intermittent aortic c... by B.M. Todurov, Yu.A. Kharenko, M.V. Khartanovich, V.B. Demyanchuk, I.Yu. Mokryk

“…The global longitudinal myocardial strain module at the end of the сardiopulmonary bypass significantly (p < 0.003) decreased to –11.9 ± 0.8 %, then gradually returned to the previous level. …”
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Dual-stream disentangled model for microvascular extraction in five datasets from multiple OCTA instruments by Xiaoyang Hu, Xiaoyang Hu, Jinkui Hao, Quanyong Yi, Yitian Zhao, Jiong Zhang

“…The introduced vascular structure prior includes low-dimensional neighborhood energy from the Distance Correlation Energy (DCE) module, which helps to better perceive the structural information of continuous vessels.Results and discussionTo precisely evaluate our method on small vessels, we delicately establish OCTA microvascular labels by performing comprehensive and detailed annotations on the FOCA dataset, which includes data collected from different instruments, and evaluated the proposed D2Net effectively mitigates the challenges of microvasculature region recognition caused by noise and artifacts. …”
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Unraveling the depth-dependent causal dynamics of methanogenesis and methanotrophy in a high-latitude fen peatland by Shuai Yang, Jinyun Tang, Zhen Li, Kunxiaojia Yuan, Qiong Wu, Kuang-Yu Chang, Suzanne B Hodgkins, Rachel M Wilson, Qing Zhu, Robert F Grant, William J Riley, Scott R Saleska, Virginia I Rich, Ruth K Varner

“…Overall, this research provides important insights into the causal mechanisms modulating CH _4 cycling across different depths, which will improve carbon cycling predictions, and guide the future field measurement strategies.…”
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TREM2 affects DAM-like cell transformation in the acute phase of TBI in mice by regulating microglial glycolysis by Lin Wang, Diqing Ouyang, Lin Li, Yunchuan Cao, Yingwen Wang, Nina Gu, Zhaosi Zhang, Zhao Li, Shuang Tang, Hui Tang, Yuan Zhang, Xiaochuan Sun, Jin Yan

“…TREM2 might influence DAM-like cell transformation by modulating the glycolysis of microglia. Our results provide a new possible pathway for intervening TBI.…”
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Genome-wide identification of novel flagellar motility genes in Pseudomonas syringae pv. tomato DC3000 by Zichu Yang, Tyler Helmann, Maël Baudin, Maël Baudin, Maël Baudin, Karl J. Schreiber, Karl J. Schreiber, Zhongmeng Bao, Paul Stodghill, Paul Stodghill, Adam Deutschbauer, Adam Deutschbauer, Jennifer D. Lewis, Jennifer D. Lewis, Bryan Swingle, Bryan Swingle

“…This leaves uncertainty about whether gene functions are conserved, especially since specific regulatory modules can have opposite functions in sets of Pseudomonas. …”
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Can enhanced CSR quality reduce the cost of debt capital? An empirical analysis of CEO expertise and non-financial reporting practices in China by Oleh Pasko, Yang Zhang, Nelia Proskurina, Vadym Sapych, Yelyzaveta Mykhailova

“…AcknowledgmentThis paper is co-funded by the European Union through the European Education and Culture Executive Agency (EACEA) within the project “EU Best Practice of Life Cycle Assessment, Social, Environmental Accounting and Sustainability Reporting” – 101047667-ERASMUS-JMO-2021-MODULE https://jm.snau.edu.ua/en/eu-best-practice-of-life-cycle-assessment-social-environmental-accounting-and-sustainability-reporting/ Oleh Pasko expresses sincere gratitude for the support from the Kirkland Research Program, generously provided by the Leaders of Change Foundation established by the Polish-American Freedom Foundation.…”
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Purinergic Signaling Pathway in Human Olfactory Neuronal Precursor Cells by Héctor Solís-Chagoyán, Edgar Flores-Soto, Marcela Valdés-Tovar, Montserrat G. Cercós, Eduardo Calixto, Luis M. Montaño, Carlos Barajas-López, Bettina Sommer, Arnoldo Aquino-Gálvez, Citlali Trueta, Gloria A. Benítez-King

“…Extracellular ATP and trophic factors released by exocytosis modulate in vivo proliferation, migration, and differentiation in multipotent stem cells (MpSC); however, the purinoceptors mediating this signaling remain uncharacterized in stem cells derived from the human olfactory epithelium (hOE). …”
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