Epigenetic Biomarkers and the Wnt/β-Catenin Pathway in Opisthorchis viverrini-associated Cholangiocarcinoma: A Scoping Review on Therapeutic Opportunities. by Alok Kafle, Sutas Suttiprapa, Mubarak Muhammad, Jan Clyden B Tenorio, Roshan Kumar Mahato, Norhidayu Sahimin, Shih Keng Loong

“…Promoter hypermethylation of specific genes suggests potential diagnostic biomarkers and dysregulation of Wnt/β-catenin-modulating genes contributes to pathway activation in Ov-CCA progression. …”
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The Response of Tissue Mast Cells to TLR3 Ligand Poly(I:C) Treatment by Piotr Witczak, Ewa Brzezińska-Błaszczyk, Justyna Agier

“…Our findings confirm that MCs may serve as active participants in the antiviral immune response. Presented data on modulated FcεRI-mediated MC secretion of mediators upon poly(I:C) treatment suggests that dsRNA-type virus infection could influence the severity of allergic reactions.…”
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The role of SASP in ischemic stroke: a deep dive into cellular mechanisms by Dong Xie, Yang Liu, Fang-Biao Xu, Jin-Sheng Zhang

“…Ccl3 and Lcp1 might potentially modulate IS progression by influencing SASP, proffering novel prospects for IS clinical diagnosis and treatment.…”
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(−)-Epigallocatechin-3-Gallate and Quercetin Inhibit Quiescin Sulfhydryl Oxidase 1 Secretion from Hepatocellular Carcinoma Cells by Lumin Yang, Yuying Fang, Yufeng He, Jinsong Zhang

“…In conclusion, our current results suggest that dietary EGCG and quercetin have the potential to be developed as adjuvants to sorafenib in the treatment of HCC by modulating the cellular distribution of QSOX1.…”
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NOL-7 serves as a potential prognostic-related biomarker for hepatocellular carcinoma by Qiucheng Lei, Yingchun Huang, Feiwen Deng, Huazhen Zheng, Xitao Hong, Peng Wang, Jin Lv, Huanwei Chen, Zhenling Ji

“…In addition, NOL7 expression was significantly correlated with cell cycle modulators, immune checkpoints, and various immune cell populations. …”
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Spectral Domain Optical Coherence Tomography Assessment of Macular and Optic Nerve Alterations in Patients with Glaucoma and Correlation with Visual Field Index by Alessio Martucci, Nicola Toschi, Massimo Cesareo, Clarissa Giannini, Giulio Pocobelli, Francesco Garaci, Raffaele Mancino, Carlo Nucci

“…Sectorial thickness values of each retinal layer and of the optic nerve were measured using SD-OCT Glaucoma Module Premium Edition (GMPE) software. Each parameter was compared between the groups, and the layers and sectors with the best area under the receiver operating characteristic curve (AUC) were identified. …”
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Transcriptional Systems Vaccinology Approaches for Vaccine Adjuvant Profiling by Diogo Pellegrina, Heather L. Wilson, George K. Mutwiri, Mohamed Helmy

“…This approach provides a narrow perspective on the complex events involved in how adjuvants modulate antigen-specific immune responses. A comprehensive and efficient way to investigate the molecular mechanism of action for adjuvants is to utilize systems biology approaches such as transcriptomics in so-called “systems vaccinology” analysis. …”
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Evidence from NHANES 2011–2014: a correlation between the weight-adjusted-waist index and cognitive abilities in the United States by Chan Zhao, Xintian Xu, Chunyan Hao

“…Three cognitive assessments were administered: the Animal Fluency Test (AFT), the Digit Symbol Substitution Test (DSST), and the Word Learning and Recall Module from the Coalition to Establish a Registry for Alzheimer’s Disease (CERAD). …”
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A Morphometric Approach to Bozkurt (Kastamonu-Türkiye) Flood by Vedat Avci, Ömer Ünsal

“…The Digital Elevation Model (DEM) of the study area was created with a cell size of 10*10 m using topography maps, and the boundaries of the basins to be analyzed with the ArcGIS-Archydro Module were determined. 30 indices were applied to these basins within the scope of shape (geometric), areal and relief morphometric features of the basins. …”
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Criteria for Detecting Turn-To-Turn Short Circuit in Stator Windings Using Vector Analysis of Electric Motor Phase Currents by I. V. Zhezhelenko, V. E. Kryvonosov, S. V. Vasilenko

“…Analytical results of the dependence of the sensitivity coefficient for turn-to-turn short circuit on the absolute increment of the modules of phase currents and the corresponding phase angles have been obtained.…”
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Development of a Bipolar Radio-frequency Power Supply for Structures of Lossless Ion Manipulations by Qing LIU, Run-ze XU, Yun-jing ZHANG, Ling-feng LI, Peng LI

“…The power supply employed an isolation module to provide electrical isolation between the control and power circuits. …”
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m6A-modified lncRNA GAS5 promotes M1-polarization of microglia in alcohol use disorder by Shuang Zhu, Peng Wang, Jian Hu

“…Long noncoding RNA (lncRNA) are essential for modulating the onset and progression of alcohol use disorder (AUD). …”
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Mixture of MMP-2, MLC, and NOS Inhibitors Affects NO Metabolism and Protects Heart from Cardiac I/R Injury by Anna Krzywonos-Zawadzka, Aleksandra Franczak, Grzegorz Sawicki, Iwona Bil-Lula

“…The aim of the current study was to provide an important insight into understanding the interaction of iNOS, eNOS, and ADMA during oxidative stress and to propose the beneficial therapy to modulate this interaction. Material and Methods. Pathogen-free Wistar rats were used in this study as a surrogate heart model ex vivo. …”
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Killer-Cell Immunoglobulin-Like Receptors (KIR) in HIV-Exposed Infants in Cameroon by Kagoué Simeni Luc-Aimé, Yindom Louis-Marie, Loni Ekali Gabriel, Clauvis Kunkeng Yengo, F. Esemu Livo, Nguedia Jules Clement Assob

“…This may be partly due to differences in host immunogenetic factors in highly polymorphic regions of the human genome such as those encoding the killer-cell immunoglobulin-like receptor (KIR) molecules which modulate the activities of natural killer cells. The primary aim of this study was to determine the variants of KIR genes that may have a role to play in MTCT in a cohort of infants born to HIV-infected mothers in Yaoundé, Cameroon. …”
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Chest wall perforator flap reconstruction in breast conserving surgery: quality of life and limited complications in outpatient treatment by L. J. van Zeelst, R. Straten, R. R. J. P. van Eekeren, D. J. P. van Uden, J. H. W. de Wilt, L. J. A. Strobbe

“…Outcomes were complication incidence and patient satisfaction reported in the Breast-Q Breast Conserving Therapy (BCT) module. Results In the study cohort, the median age was 59.5 (49.8–71.3) years. …”
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Simulation of Thin-Film Solar Cells with a CuInSe2 Chalcopyrite Structure by A. K. Esman, G. L. Zykov, V. A. Potachits, V. K. Kuleshov

“…A model of the proposed thin-film solar cell was implemented in the COMSOL Multiphysics program environment with the use of the Heat Transfer Module. The operating temperatures of the solar cell without thermal stabilization under conditions of the diurnal and seasonal variations of both the ambient temperature and the power density of the AM1.5 solar spectrum have been determined. …”
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Ningxiang pig-derived Lactobacillus reuteri improves the gut health of weaned piglets by regulating intestinal barrier function and cytokine profiles by Qian Xie, Mei Yang, Qing Duanmu, Meng Kang, Jing Wang, Bi E Tan

“…This study demonstrates that L. reuteri isolated from Ningxiang pigs can improve the intestinal health of weaned piglets by modulating gut barrier function and cytokine levels.…”
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Computational analysis of congenital heart disease associated SNPs: unveiling their impact on the gene regulatory system by Shikha Vashisht, Costantino Parisi, Cecilia L. Winata

“…Overall, our findings demonstrate that SNPs have the potential to disrupt gene regulatory systems, either by affecting enhancer sequences or modulating protein-protein interactions, which can lead to abnormal developmental processes contributing to CHD pathogenesis.…”
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Dietary Supplementation of Solid-state Fermented Yellow Mealworm (Tenebrio molitor) Larvae Meal Enriched by Lactobacillus sp. in Guppy (Poecilia reticulata) by Doğukan Kaya, Ercüment Genç, Şenay Sarıca, Musa Yavuz

“…In conclusion, solid-state fermented yellow mealworm larvae meal via 2 g/kg L. plantarum plus 2 g/kg L. brevis can improve growth performance by modulating the gut microbiota of guppies.…”
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Hepatic and immune modulatory effectiveness of lactoferrin loaded Selenium nanoparticles on bleomycin induced hepatic injury by Khaled G. Abdel-Wahhab, Mahmoud Ashry, Laila K. Hassan, Marwa H. El-Azma, Ghada M. Elqattan, Mohamed H. A. Gadelmawla, Fathia A. Mannaa

“…Post-treatment of BLM-intoxicated rats with LF, SeNPs or LF/SeNPs combination obviously improved the BLM-induced hepatic damages; this was achieved from the marked modulations in the mentioned parameters, besides improving the histopathological hepatic architecture. …”
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