-
6221
Antibacterial activity and impact on keratinocyte cell growth of Cutibacterium acnes bacteriophages in a Cutibacterium acnes IA1- colonized keratinocyte model
Published 2025-01-01“…Moreover, bacteriophages (phages) may modulate the microbiota and immune responses. Some studies have shown the potential use of phages in the treatment of acne. …”
Get full text
Article -
6222
GmERF57 negatively regulates root development and phosphate absorption in soybean
Published 2025-03-01“…We further uncovered that GmERF57 physically interacts with GmTUB1 (β-tubulin protein) and modulates soybean root architecture and Pi uptake capacity by downregulating GmTUB1 and other Pi starvation response genes. …”
Get full text
Article -
6223
Effect of Kinases in Extracellular Vesicles from HIV-1-Infected Cells on Bystander Cells
Published 2025-01-01“…These kinases were shown to be biologically active and capable of phosphorylating substrates, and they modulated changes in the cell cycle dynamics of exposed cells. …”
Get full text
Article -
6224
Enhanced interannual variability of the terrestrial carbon sink in China under high emissions
Published 2025-01-01“…However, how these future changes will modulate the IAV of China’s terrestrial carbon sinks remains unclear. …”
Get full text
Article -
6225
Molecular insights into the functional role of PbNRT2.4 in potassium homeostasis and nutrient transport in Pyrus ussuriensis
Published 2025-03-01“…Interactions among PbNRT2.4, PbHAK11, and PbSDH1 proteins, elucidated using yeast two-hybrid, BiFC, and Co-IP assays, are crucial for modulating carbon and nitrogen metabolic processes, thereby harmonizing K+ absorption and transport. …”
Get full text
Article -
6226
The endonuclease activity of MCPIP1 controls the neoplastic transformation of epithelial cells via the c-Met/CD44 axis
Published 2025-01-01“…These findings highlight the critical role of MCPIP1 RNase activity in modulating the c-Met/CD44 axis, thereby influencing stemness and tumorigenesis.…”
Get full text
Article -
6227
Techno-economic analysis of cutting-edge PV systems deployment and reconfigurations on rooftop industrial building in Saudi Arabia’s eastern region
Published 2025-01-01“…By meticulously simulating and comparing five advanced PV technologies across various configurations, the research identifies the N-type Mono BIFACIAL module in the third configuration scenario as the most effective. …”
Get full text
Article -
6228
STAT3-Inducible Mouse ESCs: A Model to Study the Role of STAT3 in ESC Maintenance and Lineage Differentiation
Published 2018-01-01“…Studies have demonstrated that STAT3 is essential in maintaining self-renewal of embryonic stem cells (ESCs) and modulates ESC differentiation. However, there is still lack of direct evidence on STAT3 functions in ESCs and embryogenesis because constitutive STAT3 knockout (KO) mouse is embryonic lethal at E6.5–E7.5, prior to potential functional role in early development can be assessed. …”
Get full text
Article -
6229
Immunomodulatory Effects of Aerobic Training in Obesity
Published 2011-01-01“…We hereby describe new immune modulatory effects, which—through regular aerobic exercise—modulate innate immunity and pro-inflammatory cytokines in obesity.…”
Get full text
Article -
6230
Weakened Effective Connectivity Related to Electroacupuncture in Stroke Patients with Prolonged Flaccid Paralysis: An EEG Pilot Study
Published 2021-01-01“…These findings may help us to modulate the formulation of electroacupuncture treatment according to different durations of the flaccid upper extremity.…”
Get full text
Article -
6231
Comparative evaluation of cell-based assay technologies for scoring drug-induced condensation of SARS-CoV-2 nucleocapsid protein
Published 2025-03-01“…There is great interest in identifying condensate modulators (CMODs), which are small molecules that alter the dynamics and functions of phase-separated condensates, as a potential therapeutic modality. …”
Get full text
Article -
6232
Distinct expression profile reveals glia involvement in the trigeminal system attributing to post-traumatic headache
Published 2024-11-01“…Conclusions Transcriptomics analysis indicated that non-neuronal cells in peripheral TG and successive in situ assays revealed that glia in the central Sp5C are crucial in modulating headache-like symptoms. Thus, selective targeting of glia cells can be a therapeutic strategy for PTH attributed to repetitive mTBI.…”
Get full text
Article -
6233
Glycyrrhizin attenuates renal inflammation in a mouse Con A-hepatitis model via the IL-25/M2 axis
Published 2024-12-01“…IL-25 regulates inflammation by modulating type 2 immune responses, but the mechanism by which IL-25 affects kidney disease remains unclear. …”
Get full text
Article -
6234
Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism
Published 2025-01-01“…Various modifications of NAD+ metabolism known to modulate SARM1 activity showed the corresponding effects on ND. …”
Get full text
Article -
6235
Engineering the Mechanics and Thermodynamics of Ti<sub>3</sub>AlC<sub>2</sub>, Hf<sub>3</sub>AlC<sub>2</sub>, Hf<sub>3</sub>GaC<sub>2</sub>, (ZrHf)<sub>3</sub>AlC<sub>2</sub>, and...
Published 2025-01-01“…Density functional theory within Quantum Espresso module was used in the computations. The Perdew–Burke–Ernzerhof generalised gradient approximation functionals were utilised. …”
Get full text
Article -
6236
Cognitive reappraisal improves the social decision-making performance of suicide attempters
Published 2025-01-01“…The present study attempted to use CR to modulate ER in SA to improve their DM performance, and explore the physiological mechanisms underlying this process. …”
Get full text
Article -
6237
Assessment of the Vanillin Anti-Inflammatory and Regenerative Potentials in Inflamed Primary Human Gingival Fibroblast
Published 2021-01-01“…Therefore, Vanillin shows a potential therapeutic interest as an inflammatory modulator molecule with novel application in periodontal regeneration and oral health.…”
Get full text
Article -
6238
TWIN-10: protocol for a 10-year longitudinal twin study of the neuroscience of mental well-being and resilience
Published 2022-07-01“…Genetic and/or environmental factors may also modulate these mechanisms. The aim of the TWIN-10 Study is to characterise the trajectories of well-being and resilience over 12 years across four timepoints (baseline, 1 year, 10 years, 12 years) in 1669 Australian adult twins of European ancestry (to account for genetic stratification effects). …”
Get full text
Article -
6239
Implemetasi Komputasi Akar Kuadrat Resolusi Tinggi pada Field Programmable Gate Array (FPGA)
Published 2022-12-01“…Proses verifikasi sistem dilakukan dalam dua tahap, yaitu verifikasi fungsional dengan aplikasi ModelSim-Altera dan verifikasi hardware menggunakan modul FPGA Cylcone IV EP4CE6E228N. Hasil verifikasi menunjukkan bahwa hasil perhitungan akar kuadrat memiliki resolusi sampai dengan 0,0039. …”
Get full text
Article -
6240
Potential involvement of peroxisome proliferator-activated receptors in the inhibition of mammary lipid synthesis during diet-induced milk fat depression
Published 2025-02-01“…We hypothesized that the expression of PPAR, which regulate lipid metabolism and bind to PUFA, could be modulated by biohydrogenation intermediates that induce MFD, thereby interfering with milk fat synthesis. …”
Get full text
Article