Showing 6,181 - 6,200 results of 6,833 for search '"modulation"', query time: 0.10s Refine Results
  1. 6181
  2. 6182

    Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway by Honghong Liu, Jiao Wang, Guanru Yue, Jixiong Xu

    Published 2024-12-01
    “…Thus, P-MSCs can significantly improve renal damage and reduce podocyte injury in DKD rats by modulating the SIRT1/FOXO1 pathway and enhancing podocyte autophagy.…”
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  3. 6183

    GTPase GPN3 facilitates cell proliferation and migration in non-small cell lung cancer by impeding clathrin-mediated endocytosis of EGFR by Linlin Xu, Jiankun Guo, Xinsheng Xie, Hailong Wang, Alan Jiang, Changhua Huang, Hua Yang, Shiwen Luo, Limin Chen

    Published 2025-02-01
    “…In this study, we demonstrate that GPN3 interacts with clathrin light chain A (CLTA), a vesicle coat protein, as well as clathrin-mediated endocytosis associated modulators AP2B1 and AP2S1. Upregulation of GPN3 leads to the inhibition of clathrin-coated pit invagination. …”
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  4. 6184

    Deep Joint Demosaicking and Super-Resolution for Spectral Filter Array Images by Abdelhamid N. Fsian, Jean-Baptiste Thomas, Jon Y. Hardeberg, Pierre Gouton

    Published 2025-01-01
    “…To this end, we use a two-branch framework, namely a pseudo-panchromatic image network and a pre-demosaicking sub-branch coupled with a novel deep residual demosaicking and super resolution module. This holistic approach ensures a more coherent and optimized restoration process, mitigating the risk of error accumulation and preserving image quality throughout the reconstruction pipeline. …”
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  5. 6185

    Exploring the Therapeutic Potential of Cannabidiol in U87MG Cells: Effects on Autophagy and NRF2 Pathway by Laura Giannotti, Benedetta Di Chiara Stanca, Francesco Spedicato, Daniele Vergara, Eleonora Stanca, Fabrizio Damiano, Luisa Siculella

    Published 2024-12-01
    “…These findings highlight the therapeutic potential of CBD, suggesting that modulating NRF2 and autophagy pathways could represent a promising strategy for glioblastoma treatment.…”
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  6. 6186

    IMPLEMENTATION OF MICROLEARNING TECHNOLOGY FOR ECONOMICS STUDENTS THROUGH ONLINE COURSES by Olena Hlazunova, Ralf Schlauderer, Valentyna Korolchuk, Tetiana Voloshyna, Taisia Sayapina, Inna Kostenko, Roman Zolotukha

    Published 2024-04-01
    “…Microlearning is a modern learning technology that involves short, intensive training modules focused on the development of specific theoretical knowledge and practical skills. …”
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  7. 6187

    Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells by Carl D. Richards, Laura Izakelian, Anisha Dubey, Grace Zhang, Steven Wong, Karen Kwofie, Aatif Qureshi, Fernando Botelho

    Published 2016-01-01
    “…IL-33 modulates both innate and adaptive immune responses at tissue sites including lung and may play critical roles in inflammatory lung disease. …”
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  8. 6188

    Cigarette and e-cigarette reversely regulated autophagy via distinct level of ROS in vitro by Yao Wang, Jialing Zhong, Zuyi Jin, An Luo, Zehong Wu, Xingtao Jiang, Jianwen Chen, Peiqing Liu, Min Li

    Published 2025-01-01
    “…Scavenge of ROS clearly eliminates the autophagy modulated by both CSC and EAC. These findings contribute to a comprehensive understanding of the cytotoxicity of e-cigarettes and conventional cigarettes, providing a scientific basis for health risk assessment and regulatory mechanisms.…”
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  9. 6189

    Non-classical pulmonary exacerbation in cystic fibrosis revealing ALK-Translocated lung cancer: A case report by Mohamad Hadhud, Johnathan Arnon, Anat Hershko-Moshe, Adi Hollander, Noa Hurvitz-Lehmann, Assaf Potruch, Henny Azmanov, Rottem Kuint, Nurith Hiller, Elie Picard, Naama Sebbag-Sznajder, Shira Leebhoff, Michael Wilschanski, Myriam Grunewald, Liron Birimberg-Schwartz, Malena Cohen-Cymberknoh

    Published 2025-01-01
    “…The deterioration observed following the initiation of ALK inhibitor treatment and subsequent improvement with CFTR modulators suggest that ALK inhibitor therapy may potentially impair CFTR activity. …”
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  10. 6190

    Integrated analysis of transcriptome, sRNAome, and degradome involved in the drought-response of maize Zhengdan958 by Yang Shuqiong, Liu Jiafei, Cao Lingling, Chen Jibao, Duan Pengfei

    Published 2025-01-01
    “…These worthwhile will promote the functional characterization of miRNA–mRNA modules response to drought stress, and potentially contribute to drought-resistance breeding of maize.…”
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  11. 6191

    HnRNPR-mediated UPF3B mRNA splicing drives hepatocellular carcinoma metastasis by Hong Wang, Dong Qian, Jiabei Wang, Yao Liu, Wenguang Luo, Hongyan Zhang, Jingjing Cheng, Heng Li, Yang Wu, Wuhan Li, Jing Wang, Xia Yang, Tianzhi Zhang, Dong Han, Qinyao Wang, Chris Zhiyi Zhang, Lianxin Liu

    Published 2025-02-01
    “…Conclusion: Our findings suggest that HnRNPR-induced UPF3B-S promotes HCC invasion and metastasis by exhausting CDH1 mRNA and modulating YAP1-Hippo signaling. UPF3B-S could potentially serve as a promising biomarker for the clinical management of invasive HCC.…”
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  12. 6192
  13. 6193

    Bacterial communities as bioindicators of climate change in freshwater ecosystems: Tank bromeliads as model systems by Daniel Di Pace Soares Penna, Gustavo Quevedo Romero, Mark P. Nessel, Angélica L. González, Valéria Maia Oliveira

    Published 2025-02-01
    “…Network analysis revealed that rare species were key connectors in highly interconnected modules, suggesting resilience in the face of environmental changes. …”
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  14. 6194

    Transcriptomic and proteomic profiling identifies feline fibrosarcoma as clinically amenable model for aggressive sarcoma subtypes by Mikiyo Weber, Daniel Fuchs, Amiskwia Pöschel, Erin Beebe, Zuzana Garajova, Armin Jarosch, Laura Kunz, Witold Wolski, Lennart Opitz, Franco Guscetti, Mirja C. Nolff, Enni Markkanen

    Published 2025-02-01
    “…While feline FSA are characterized by hyperactive EIF2, TP53 and MYC signaling, immune-related and neuronal pathways emerge as modulators of tumor aggressiveness and immunosuppression. …”
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  15. 6195

    Glucagon-like peptide 1 receptor agonists in obesity treatment - a literature review by Aleksander Jentkiewicz, Esmail Haj Obeid, Jakub Ulrych, Jan Krupa, Maciej Malinowski, Michał Krasowski, Alicja Kalinowska, Wiktoria Pietras, Adrian Kozieł, Zofia Kurek

    Published 2025-02-01
    “…Description of the State of Knowledge: GLP-1 receptor agonists modulate appetite, resulting in lower calory intake. …”
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  16. 6196

    Autophagy-Enhancing Properties of <i>Hedyotis diffusa</i> Extracts in HaCaT Keratinocytes: Potential as an Anti-Photoaging Cosmetic Ingredient by Qiwen Zheng, Xiangji Jin, Trang Thi Minh Nguyen, Eun-Ji Yi, Se-Jig Park, Gyeong-Seon Yi, Su-Jin Yang, Tae-Hoo Yi

    Published 2025-01-01
    “…Our findings indicate that HD promotes autophagy by modulating the PI3K/AKT/mTOR and PINK/PARK2 pathways, which stabilizes mitochondrial quality, maintains MMP and Ca<sup>2+</sup> balance, and reduces cytochrome c release. …”
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  17. 6197

    RL-ADN: A high-performance Deep Reinforcement Learning environment for optimal Energy Storage Systems dispatch in active distribution networks by Shengren Hou, Shuyi Gao, Weijie Xia, Edgar Mauricio Salazar Duque, Peter Palensky, Pedro P. Vergara

    Published 2025-01-01
    “…A standout feature of RL-ADN is its data augmentation module, based on Gaussian Mixture Model and Copula (GMC) functions, which elevates the performance ceiling of DRL agents, achieving an average performance improvement of 21.43%, 1.08%, 2.76%, by augmenting five-year, one-year and three-month data, respectively. …”
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  18. 6198

    Modeling automatic horizontation system of steep-sloping mobile machine with hydraulic sensor roll by V. I. Grishchenko, A. A. Tumakov, M. S. Poleshkin, M. S. Kilina, D. D. Dymochkin

    Published 2019-04-01
    “…A computational experiment is performed in the Matlab Simulink software environment based on the modules of the Simscape subroutine using numerical methods, which allowed to identify processes under varying loads on the chassis of mobile machine. …”
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  19. 6199

    Altered NKp30, NKp46, NKG2D, and DNAM-1 Expression on Circulating NK Cells Is Associated with Tumor Progression in Human Gastric Cancer by Bin Han, Fang-yuan Mao, Yong-liang Zhao, Yi-pin Lv, Yong-sheng Teng, Mubing Duan, Weisan Chen, Ping Cheng, Ting-ting Wang, Zhong-yuan Liang, Jin-yu Zhang, Yu-gang Liu, Gang Guo, Quan-ming Zou, Yuan Zhuang, Liu-sheng Peng

    Published 2018-01-01
    “…The tumor microenvironment can suppress NK cell activity, and there is a great clinical interest in understanding whether modulating tumor-mediated NK cell suppression and/or boosting preexisting NK cell numbers in cancer patients is therapeutically viable. …”
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  20. 6200

    YOLO-UP: A High-Throughput Pest Detection Model for Dense Cotton Crops Utilizing UAV-Captured Visible Light Imagery by Chenglei Sun, Afizan Bin Azman, Zaiyun Wang, Xiaoxiao Gao, Kai Ding

    Published 2025-01-01
    “…YOLO-PEST incorporates a custom-designed SC3 module to enhance low-level feature extraction and employs the GeLU activation function to address the vanishing gradient issue. …”
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