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6181
Lipids in parenteral nutrition – expert consensus statements: Translating guidelines into clinical practice
Published 2025-04-01“…In addition, lipids modulate a variety of biological functions, including inflammatory and immune responses. …”
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6182
Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway
Published 2024-12-01“…Thus, P-MSCs can significantly improve renal damage and reduce podocyte injury in DKD rats by modulating the SIRT1/FOXO1 pathway and enhancing podocyte autophagy.…”
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6183
GTPase GPN3 facilitates cell proliferation and migration in non-small cell lung cancer by impeding clathrin-mediated endocytosis of EGFR
Published 2025-02-01“…In this study, we demonstrate that GPN3 interacts with clathrin light chain A (CLTA), a vesicle coat protein, as well as clathrin-mediated endocytosis associated modulators AP2B1 and AP2S1. Upregulation of GPN3 leads to the inhibition of clathrin-coated pit invagination. …”
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6184
Deep Joint Demosaicking and Super-Resolution for Spectral Filter Array Images
Published 2025-01-01“…To this end, we use a two-branch framework, namely a pseudo-panchromatic image network and a pre-demosaicking sub-branch coupled with a novel deep residual demosaicking and super resolution module. This holistic approach ensures a more coherent and optimized restoration process, mitigating the risk of error accumulation and preserving image quality throughout the reconstruction pipeline. …”
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6185
Exploring the Therapeutic Potential of Cannabidiol in U87MG Cells: Effects on Autophagy and NRF2 Pathway
Published 2024-12-01“…These findings highlight the therapeutic potential of CBD, suggesting that modulating NRF2 and autophagy pathways could represent a promising strategy for glioblastoma treatment.…”
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6186
IMPLEMENTATION OF MICROLEARNING TECHNOLOGY FOR ECONOMICS STUDENTS THROUGH ONLINE COURSES
Published 2024-04-01“…Microlearning is a modern learning technology that involves short, intensive training modules focused on the development of specific theoretical knowledge and practical skills. …”
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6187
Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells
Published 2016-01-01“…IL-33 modulates both innate and adaptive immune responses at tissue sites including lung and may play critical roles in inflammatory lung disease. …”
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6188
Cigarette and e-cigarette reversely regulated autophagy via distinct level of ROS in vitro
Published 2025-01-01“…Scavenge of ROS clearly eliminates the autophagy modulated by both CSC and EAC. These findings contribute to a comprehensive understanding of the cytotoxicity of e-cigarettes and conventional cigarettes, providing a scientific basis for health risk assessment and regulatory mechanisms.…”
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6189
Non-classical pulmonary exacerbation in cystic fibrosis revealing ALK-Translocated lung cancer: A case report
Published 2025-01-01“…The deterioration observed following the initiation of ALK inhibitor treatment and subsequent improvement with CFTR modulators suggest that ALK inhibitor therapy may potentially impair CFTR activity. …”
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6190
Integrated analysis of transcriptome, sRNAome, and degradome involved in the drought-response of maize Zhengdan958
Published 2025-01-01“…These worthwhile will promote the functional characterization of miRNA–mRNA modules response to drought stress, and potentially contribute to drought-resistance breeding of maize.…”
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6191
HnRNPR-mediated UPF3B mRNA splicing drives hepatocellular carcinoma metastasis
Published 2025-02-01“…Conclusion: Our findings suggest that HnRNPR-induced UPF3B-S promotes HCC invasion and metastasis by exhausting CDH1 mRNA and modulating YAP1-Hippo signaling. UPF3B-S could potentially serve as a promising biomarker for the clinical management of invasive HCC.…”
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6192
CircRNF13 enhances IGF2BP1 phase separation-mediated ITGB1 mRNA stabilization in an m6A-dependent manner to promote oral cancer cisplatin chemoresistance
Published 2025-01-01“…The m6A modification of ITGB1 mRNA is modulated by the phase separation of IGF2BP1, thereby promoting the malignant progression of oral cancer cells. …”
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6193
Bacterial communities as bioindicators of climate change in freshwater ecosystems: Tank bromeliads as model systems
Published 2025-02-01“…Network analysis revealed that rare species were key connectors in highly interconnected modules, suggesting resilience in the face of environmental changes. …”
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6194
Transcriptomic and proteomic profiling identifies feline fibrosarcoma as clinically amenable model for aggressive sarcoma subtypes
Published 2025-02-01“…While feline FSA are characterized by hyperactive EIF2, TP53 and MYC signaling, immune-related and neuronal pathways emerge as modulators of tumor aggressiveness and immunosuppression. …”
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6195
Glucagon-like peptide 1 receptor agonists in obesity treatment - a literature review
Published 2025-02-01“…Description of the State of Knowledge: GLP-1 receptor agonists modulate appetite, resulting in lower calory intake. …”
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6196
Autophagy-Enhancing Properties of <i>Hedyotis diffusa</i> Extracts in HaCaT Keratinocytes: Potential as an Anti-Photoaging Cosmetic Ingredient
Published 2025-01-01“…Our findings indicate that HD promotes autophagy by modulating the PI3K/AKT/mTOR and PINK/PARK2 pathways, which stabilizes mitochondrial quality, maintains MMP and Ca<sup>2+</sup> balance, and reduces cytochrome c release. …”
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6197
RL-ADN: A high-performance Deep Reinforcement Learning environment for optimal Energy Storage Systems dispatch in active distribution networks
Published 2025-01-01“…A standout feature of RL-ADN is its data augmentation module, based on Gaussian Mixture Model and Copula (GMC) functions, which elevates the performance ceiling of DRL agents, achieving an average performance improvement of 21.43%, 1.08%, 2.76%, by augmenting five-year, one-year and three-month data, respectively. …”
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6198
Modeling automatic horizontation system of steep-sloping mobile machine with hydraulic sensor roll
Published 2019-04-01“…A computational experiment is performed in the Matlab Simulink software environment based on the modules of the Simscape subroutine using numerical methods, which allowed to identify processes under varying loads on the chassis of mobile machine. …”
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6199
Altered NKp30, NKp46, NKG2D, and DNAM-1 Expression on Circulating NK Cells Is Associated with Tumor Progression in Human Gastric Cancer
Published 2018-01-01“…The tumor microenvironment can suppress NK cell activity, and there is a great clinical interest in understanding whether modulating tumor-mediated NK cell suppression and/or boosting preexisting NK cell numbers in cancer patients is therapeutically viable. …”
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6200
YOLO-UP: A High-Throughput Pest Detection Model for Dense Cotton Crops Utilizing UAV-Captured Visible Light Imagery
Published 2025-01-01“…YOLO-PEST incorporates a custom-designed SC3 module to enhance low-level feature extraction and employs the GeLU activation function to address the vanishing gradient issue. …”
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