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5981
Glycosylation of ceramide synthase 6 is required for its activity
Published 2025-01-01“…However, the mechanisms by which ceramide modulates ER stress signaling are not well understood. …”
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5982
Integrated analysis of cellulose structure and properties using solid-state low-field H-NMR and photoacoustic spectroscopy
Published 2025-01-01“…Complementing this, we investigate the photo-absorption properties of cellulose fibers under both continuous and modulated irradiation using reversed double-beam photoacoustic spectroscopy (RDB-PAS). …”
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5983
Effect of the overhead height and tilt angle on comprehensive performance of photovoltaic roof based on simulation and experimental methods
Published 2025-03-01“…Therefore, this paper established a simulated model to investigate the impact of various overhead heights and tilt angles of photovoltaic modules on thermal and electrical performance, as well as energy-saving benefits. …”
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5984
Bioelectronic osteosynthesis plate to monitor the fracture bone healing using electric capacitive variations
Published 2025-01-01“…Our technology includes a network-architectured capacitive interdigitated system, a Bluetooth module, an analog-to-digital converter, a multiplexer, a microcontroller, and a miniaturized battery. …”
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5985
Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy
Published 2024-12-01“…This study showcases an approach to developing immune-modulating therapeutics that prioritizes safety and has the potential to advance cancer immunotherapy treatment strategies.…”
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5986
Development and Complex Dynamics at School Environment
Published 2018-01-01“…Our findings show that participating in the intervention positively modulated social interactions since we found an increase in the diversity and quality of positive links and a reduction in negative ones; a higher level of integration, indicated by enhanced positive networks where children with many positive connections tended to connect with those with few links; and more positive interactions between genders. …”
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5987
Inhibition of BRD4 attenuated IFNγ-induced apoptosis in colorectal cancer organoids
Published 2025-01-01“…Conclusions Our results showed that the inhibition of Brd4 suppressed IFNγ-induced cytotoxicity by modulating the Jak-Stat pathway. These data suggested that the inhibition of Brd4 could increase cell viability in the cancer microenvironment where IFNγ is abundant, revealing a new aspect of the molecular mechanism of CRC development. …”
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5988
Beyond modular and non-modular states: theoretical considerations, exemplifications, and practical implications
Published 2025-01-01“…We begin by analyzing the contributions of Sternberg and Fodor, whose foundational work established the concept of specialized, encapsulated modules within cognitive processes, particularly in the domains of perception and language. …”
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5989
Multimodal heterogeneous graph fusion for automated obstructive sleep apnea-hypopnea syndrome diagnosis
Published 2024-11-01“…Additionally, a multi-head fusion module combines these features into a unified representation for effective classification, enhancing focus on relevant signal characteristics and cross-modal interactions. …”
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5990
IFN Regulatory Factor 1 Mediates Macrophage Pyroptosis Induced by Oxidized Low-Density Lipoprotein in Patients with Acute Coronary Syndrome
Published 2019-01-01“…The overexpression or inhibition of IRF-1 effectively modulated caspase-1 activation, as well as macrophage lysis, expression of gasdermin D-N (GSDMD-N), production of IL-1β and IL-18, and activation of NLRP3-ASC inflammasome, which were all inhibited by caspase-1 inhibitor. …”
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5991
Zonisamide Enhances Motor Effects of Levodopa, Not of Apomorphine, in a Rat Model of Parkinson’s Disease
Published 2018-01-01“…In conclusion, zonisamide appears to generate its antiparkinsonian effects by modulating levodopa-dopamine metabolism in the parkinsonian striatum.…”
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5992
Overview of Solar Photovoltaic MPPT Methods: A State of the Art on Conventional and Artificial Intelligence Control Techniques
Published 2024-01-01“…Well-written descriptions of the features of photovoltaic modules are followed by a variety of effective control strategies, including both AI-based and traditional controllers. …”
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5993
New era, new GOALs: cardiovascular screening and lipid management in cystic fibrosis
Published 2025-02-01“…While cholesterol levels were historically low in pwCF, higher levels after initiating highly effective modulator therapy (HEMT) have been reported. Mechanisms are unclear and there is little guidance on screening. …”
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5994
Nogo Osing Apps: Aplikasi Smart Farming Buah Naga Berbasis IoT
Published 2024-02-01“…Kombinasi arduino, microcontroller, sensor flow, soil moisture dan modul relay dapat memonitoring suhu dan kelembaban tanah guna menghasilkan buah naga yang optimal. …”
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5995
The Interannual Relationship between the Diabatic Heating over the South Asia and the Snow Depth over the Southern Tibetan Plateau in Late Spring to Early Summer: Roles of the Air...
Published 2023-01-01“…But we could not prove that these diabatic heating anomalies can affect the SD over the southern TP by modulating local surface air temperature. This may be limited by the quality of the data and the simulation capability of the simple model.…”
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5996
IncSAR: A Dual Fusion Incremental Learning Framework for SAR Target Recognition
Published 2025-01-01“…To mitigate the speckle noise inherent in SAR images, we employ a denoising module based on a neural network approximation of Robust Principal Component Analysis (RPCA), leveraging a simple neural network for efficient noise reduction in SAR imagery. …”
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5997
Docosahexaenoic and Eicosapentaenoic Acid Supplementation Could Attenuate Negative Effects of Maternal Metabolic Syndrome on Liver Lipid Metabolism and Liver Betacellulin Expressio...
Published 2025-01-01“…<b>Conclusions</b>: The changes observed in this study suggest that DHA/EPA supplementation may modulate the effects of maternal programming on disorders of the lipid metabolism in the offspring.…”
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5998
Ultrafine dendritic Cu particles for extremely fast pressure-assisted sintering under air and pore-free bond lines
Published 2025-03-01“…To overcome the bottleneck of the die-attach process in the manufacture of power modules based utilizing band gap semiconductors, an extremely fast pressure-assisted sinter-bonding method employing a low-cost Cu paste was developed. …”
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5999
Synergistic therapeutic approach for hemorrhoids: integrating mesenchymal stem cells with diosmin-hesperidin to target tissue edema and inflammation
Published 2024-10-01“…Conclusions These findings suggest that MSCs play a crucial role in modulating TNF-α, TGF-β, collagen remodeling, and MMP-9 activity, highlighting their promising role in hemorrhoid treatment and wound healing processes. …”
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6000
Optimization of Enterprise Financial Management and Decision-Making Systems Based on Big Data
Published 2022-01-01“…The integration of industry and finance is essentially achieved through the application of various financial management modules to the business operations of enterprises, including budget management, capital management, fixed asset management, and financial accounting. …”
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