Astragaloside IV inhibits atherosclerosis caused by ferritin autophagy in a lipid deposition environment by activating Nrf2 by Dandan Liu, Hewei Qin, Guanghua Liu, Yang Gao, Yu Guo

“…In addition, astragaloside IV has lipid-modulating and antioxidant pharmacological potential. …”
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p104 Binds to Rac1 and Reduces Its Activity during Myotube Differentiation of C2C12 Cell by Ki Young Choi, Min Sup Lee, Young Jun Cho, Myong Ho Jeong, Seung Jin Han, Seung Hwan Hong

“…Based on these results, we conclude that p104 is involved in muscle cell differentiation by modulating the Rac1 activity.…”
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Ultra‐Thin Strain‐Relieving Si1−xGex Layers Enabling III‐V Epitaxy on Si by Trevor R. Smith, Spencer McDermott, Vatsalkumar Patel, Ross Anthony, Manu Hedge, Sophie E. Bierer, Sunzhuoran Wang, Andrew P. Knights, Ryan B. Lewis

“…The efficient strain relaxation results from the high oxidation temperature, producing a periodic network of dislocations at the substrate interface, coinciding with modulations of the Ge content in the Si1−xGex layer and indicating the presence of defect‐mediated diffusion of Si through the layer. …”
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Platelet‐derived apoptotic vesicles ameliorate nonalcoholic fatty liver disease by regulating lipid metabolism via apolipoprotein A‐II by Yuhe Jiang, Yike Liao, Zeying Wang, Lei Zhu, Yunsong Liu, Ping Zhang, Yuan Zhu, Wenyue Li, Yongsheng Zhou, Xiao Zhang

“…This underscores the need for improved therapeutic approaches that can modulate lipid metabolism and halt the transition from liver steatosis to chronic liver disease. …”
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How do age and sex influence pain threshold and tolerance among Santal tribal people living in West Bengal, India? by Arpita Santra, Subrata Kumar Roy, Monali Goswami, Diptendu Chatterjee

“…Notably, age and sex have consistently emerged as pivotal determinants in modulating pain perception. The study aimed to examine age and sex differences in pain threshold and tolerance levels. …”
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Beneficial Roles of 1-MCP on Regulation of Photosynthetic Electron Transport and Energy Dissipation in Chrysanthemum Under Heat Stress by Runtian Miao, Xiaoman Liu, Yilin Zhao, Yanli Zhao, Han Dong, Gan Huang, Yonghua Li

“…Here, the chlorophyll a fluorescence and modulated 820 nm reflection transients were analyzed in heat-tolerant and heat-sensitive chrysanthemum plants. …”
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Pharmacological Characterization of the Mechanisms Involved in Delayed Calcium Deregulation in SH-SY5Y Cells Challenged with Methadone by Sergio Perez-Alvarez, Maria E. Solesio, Maria D. Cuenca-Lopez, Raquel M. Melero-Fernández de Mera, Carlos Villalobos, Hanna Kmita, Maria F. Galindo, Joaquin Jordán

“…Only those compounds targeting mitochondria such as oligomycin, FCCP, CGP 37157, and cyclosporine A were able to amend methadone-induced Ca2+ dyshomeostasis suggesting that methadone induces DCD by modulating the ability of mitochondria to handle Ca2+. …”
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Flexible modular dwelling for rural environments; specific case: Cebadas – Ecuador [version 2; peer review: 2 approved] by Karina Elizabeth Cajamarca Dacto, Maikol Josueé González Espinosa, Dany Marcelo Tasan Cruz, Erick Fabricio Nieto Páez, Jean Carlos Montero Riofrio

“…Conclusions The flexible modular dwelling project for rural environments addresses complex housing needs, highlighting the flexibility and adaptability of an expandable module. It includes income generation with a duplex apartment, fosters communal and cultural life with public and commercial spaces, promotes tourism and rural development with landscape design and crops. …”
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Association of The MCP-1 rs1024611 Polymorphism with Polycystic Ovary Syndrome in A Population of Indian Women: A Case-Control Study by Jijo Francis, Honey Sebastian, Saley Daniel, Leyon Varghese, Sareena Gilvaz, Ragitha Thenkattil Sankarankutty, Siji Susan George, Pulikkottil Raphael Varghese, Suresh Kumar Raveendran

“…Genetic variations in the MCP-1 gene may modulate MCP-1 expression. Although the association of theMCP-1 promoter polymorphism (-2518A/G) was extensively studied in different inflammatory conditions, there isonly one report in PCOS conditions. …”
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Dynamics of Charge Transients in High Voltage Silicon and SiC NPN BJT Under High Injection Levels by Mana Hosseinzadehlish, Saeed Jahdi, Konstantinos Floros, Ingo Ludtke, Xibo Yuan

“…A range of base currents modulated by base resistors are employed with two load inductors to enable a wide range of switching conditions at different switching rates. …”
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Molecular Mechanisms Underlying Neuroinflammation Intervention with Medicinal Plants: A Critical and Narrative Review of the Current Literature by Sandra Maria Barbalho, Beatriz Leme Boaro, Jéssica da Silva Camarinha Oliveira, Jiří Patočka, Caroline Barbalho Lamas, Masaru Tanaka, Lucas Fornari Laurindo

“…Here, we highlight that medicinal plants are effective modulators of neuroinflammation, underscoring their therapeutic potential. …”
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NERVE 2.0: boosting the new enhanced reverse vaccinology environment via artificial intelligence and a user-friendly web interface by Andrea Conte, Nicola Gulmini, Francesco Costa, Matteo Cartura, Felix Bröhl, Francesco Patanè, Francesco Filippini

“…We renewed some of its modules and added innovative ones, such as Loop-Razor, to recover fragments of promising vaccine candidates or Epitope Prediction for the epitope prediction binding affinities and population coverage. …”
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V-ATPase in glioma stem cells: a novel metabolic vulnerability by Alessandra Maria Storaci, Irene Bertolini, Cristina Martelli, Giorgia De Turris, Nadia Mansour, Mariacristina Crosti, Maria Rosaria De Filippo, Luisa Ottobrini, Luca Valenti, Elisa Polledri, Silvia Fustinoni, Manuela Caroli, Claudia Fanizzi, Silvano Bosari, Stefano Ferrero, Giorgia Zadra, Valentina Vaira

“…Methods V-ATPase activity in GSC cultures was modulated using Bafilomycin A1 (BafA1) and cell viability and metabolic traits were analyzed using live assays. …”
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CPK1 activates CNGCs through phosphorylation for Ca2+ signaling to promote root hair growth in Arabidopsis by Meijun Zhu, Bo-Ya Du, Yan-Qiu Tan, Yang Yang, Yang Zhang, Yong-Fei Wang

“…Thus we discover the CPK1-CNGC modules essential for the Ca2+ signaling regulation and RH growth in Arabidopsis.…”
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The Role of Adjuvant Radiotherapy for a Case of Primary Breast Sarcoma: A Plan Comparison between Three Modern Techniques and a Review of the Literature by Mariella Cozzolino, Caterina Oliviero, Barbara D’Andrea, Giuseppe Guglielmi, Giorgia Califano, Rocchina Caivano, Antonella Bianculli, Vincenzo Fusco

“…To identify the best radiotherapy technique for this patient, three methods were compared: 3D conformal radiotherapy (3D-CRT), intensity-modulated radiation therapy (IMRT), and volumetric arc therapy (VMAT) or RapidArc® (RA). 50 Gy was prescribed to the chest wall and 66 Gy to the tumor bed. …”
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Micro-/nanobubble oxygenation irrigation enhances soil phosphorus availability and yield by altering soil bacterial community abundance and core microbial populations by Qingyong Bian, Qingyong Bian, Zhiduo Dong, Yupeng Zhao, Yaozu Feng, Yaozu Feng, Yaozu Feng, Yanbo Fu, Yanbo Fu, Zhiguo Wang, Jingquan Zhu, Liang Ma

“…In conclusion, the application of micro-/nanobubble oxygenation irrigation enhances the activity of alkaline phosphatasein the soil by modulating the microbial community within the rhizosphere, thereby facilitating increased phosphorus availability in the rhizosphere of maize.…”
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IL-33 Protects Mice against DSS-Induced Chronic Colitis by Increasing Both Regulatory B Cell and Regulatory T Cell Responses as Well as Decreasing Th17 Cell Response by Jun-feng Zhu, Ying Xu, Jian Zhao, Xue Li, Xinrui Meng, Tian-qi Wang, Ben-yao Zou, Peng-yan Zhao, Qi Liu, Chang-long Lu, Fang-liang Zheng, Hong-sheng Liu

“…Previously, we have reported that IL-33 functioned as a protective modulator in dextran sulfate sodium- (DSS-) induced chronic colitis by suppressing Th17 cell response in colon lamina propria and IL-33 induced both regulatory B cells (Bregs) and regulatory T cells (Tregs) in mesenteric lymph nodes (MLNs) of mice with DSS-induced acute colitis. …”
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Median Preoptic Nucleus Mediates the Cardiovascular Recovery Induced by Hypertonic Saline in Hemorrhagic Shock by Nathalia Oda Amaral, Lara Marques Naves, Marcos Luiz Ferreira-Neto, André Henrique Freiria-Oliveira, Eduardo Colombari, Daniel Alves Rosa, Angela Adamski da Silva Reis, Danielle Ianzer, Carlos Henrique Xavier, Gustavo Rodrigues Pedrino

“…Changes in plasma osmolarity, through central and peripheral osmoreceptors, activate the median preoptic nucleus (MnPO) that modulates autonomic and neuroendocrine adjustments. …”
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Pseudomonas cold shock proteins suppress bacterial effector translocation in Nicotiana benthamiana by Shen Cong, Jun-Zhou Li, Mei-Ran Zhang, Mei-Ran Zhang, Hai-Lei Wei, Wei Zhang

“…Here, we employed this model system to explore the in vivo roles of CSPs in modulating plant immunity by multiple genetic approaches.ResultsOur findings revealed that three highly-conserved CSPs were identified in Pseudomonas strains. …”
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Comparative Analysis of Immunoactivation by Nanosecond Pulsed Electric Fields and PD-1 Blockade in Murine Hepatocellular Carcinoma by Maiweilidan Yimingjiang, Talaiti Tuergan, Xinhua Chen, Hao Wen, Yingmei Shao, RuiQing Zhang, Kasimu Aihaiti, Jing Xue, Tuerganaili Aji, Wei Zhang

“…Both nsPEF ablation and anti-PD-1 treatment induced immune cell infiltration in local tumors and modulated cytokine levels in the peripheral blood, with distinct changes in the two treatment groups. …”
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