Multiscale guided attention network for optic disc segmentation of retinal images by A Z M Ehtesham Chowdhury, Andrew Mehnert, Graham Mann, William H. Morgan, Ferdous Sohel

“…The decoder also includes a guided attention module that incorporates features related to structural, contextual, and illumination information to segment OD. …”
Get full text

Osteoprotegerin as an Emerging Biomarker of Carotid Artery Stenosis? A Scoping Review with Meta-Analysis by Jerzy Chudek, Marta Pośpiech, Anna Chudek, Michał Holecki, Monika Puzianowska-Kuźnicka

“…Osteoprotegerin (OPG), a soluble member of the tumor necrosis factor receptor (TNFR) superfamily, is considered a modulator of vascular calcification linked to vascular smooth muscle cell proliferation and collagen production in atherosclerotic plaques. …”
Get full text

Effect of Obesity-Linked FTO rs9939609 Variant on Physical Activity and Dietary Patterns in Physically Active Men and Women by Nathan R. West, James Dorling, Alice E. Thackray, Nicola C. Hanson, Samantha E. Decombel, David J. Stensel, Stuart J. Grice

“…Single nucleotide polymorphisms (SNPs) in the fat mass and obesity-associated (FTO) locus are associated with obesity, but lifestyle factors may modulate the obesity risk related to FTO. This study examined the physical activity and dietary patterns of 528 physically active white men and women (mean (SD): 34.9 (9.5) years, 26.6 (4.3) kg·m−2) carrying different risk variants of FTO SNP rs9939609. …”
Get full text

Approximation-Aware Training for Efficient Neural Network Inference on MRAM Based CiM Architecture by Hemkant Nehete, Sandeep Soni, Tharun Kumar Reddy Bollu, Balasubramanian Raman, Brajesh Kumar Kaushik

“…This architecture includes a mapping algorithm that modulates inputs and map AFC to crossbar arrays directly, eliminating the need to predict approximated weights for evaluating output. …”
Get full text

Virtual reality in pediatric emergency department and burn unit: a scoping review of current applications by Ignazio Cammisa, Gemma Eftimiadi, David Korn, Serena Ferretti, Lavinia Capossela, Antonio Gatto, Antonio Chiaretti

“…VR has the ability to modulate both the sensory and emotional components of pain by immersing children in a virtual world, effectively diverting their attention from the painful experience. …”
Get full text

Effects of collagen and chondroitin sulfate on relaxation at multiple magnetic field strengths by Olli-Pekka Aro, Victor Casula, Nina E. Hänninen, Jouni Karjalainen, Mikko J. Nissi, Miika T. Nieminen, Henning Henschel

“…Conclusions: Our results suggest that R1, R2, and R1ρ are modulated by collagen and CS concentrations, with collagen likely dominating at physiological concentrations.…”
Get full text

RECQL4 requires PARP1 for recruitment to DNA damage, and PARG dePARylation facilitates its associated role in end joining by Mansoor Hussain, Prabhat Khadka, Komal Pekhale, Tomasz Kulikowicz, Samuel Gray, Alfred May, Deborah L. Croteau, Vilhelm A. Bohr

“…Consequently, the combined activities of PARP1, PARG and RECQL4 modulate DNA repair.…”
Get full text

Tumor Anti-Initiation and Anti-Progression Properties of Sulphated-Extract of Colocasia esculenta by Amira M. Gamal-Eldeen, Hassan Amer ‎, Cinderella A. ‎ Fahmy, Haytham ‎ Dahlawi, Basem H ‎ Elesawy, Nahla L. ‎ Faizo, Bassem M. ‎ Raafat

“…It induced lymphocyte growth and modulated the macrophage functions into an anti-inflammatory profile, via elevating macrophage proliferation and its binding affinity of fluorescein isothiocyanate-lipopolysaccharide (FITC-LPS) and inhibiting nitric oxide and tumor necrosis factor-α generation. …”
Get full text

Mature Tiankengs are biodiversity hotspots of soil microorganisms in the karst region by Junbo Yang, Xiaohui Wang, Keyi Wang, Danjuan Zeng, Ling Mo, Shuai Li, Baozhu Fang, Bhagwan Rekadwad, Wenjun Li, Gaozhong Pu

“…Compare to the outside, more bacterial and fungal species in Tiankeng assembled more network modules as well as microbial functions. Results suggested that compared with the outside, rich soil nutrients may contribute the higher microbial diversity and function formed in mature Tiankengs. …”
Get full text

Lnc-DC promotes estrogen independent growth and tamoxifen resistance in breast cancer by Wan-Xin Peng, Pratirodh Koirala, Huaixiang Zhou, Jiahong Jiang, Ziqiang Zhang, Liu Yang, Yin-Yuan Mo

“…Abstract Selective estrogen receptor modulators (SERMs) such as tamoxifen have proven to be effective in the treatment of estrogen receptor (ER) positive breast cancer. …”
Get full text

Neural activity responsiveness by maturation of inhibition underlying critical period plasticity by Ibuki Matsumoto, Sou Nobukawa, Sou Nobukawa, Sou Nobukawa, Sou Nobukawa, Takashi Kanamaru, Takashi Kanamaru, Yusuke Sakemi, Yusuke Sakemi, Nina Sviridova, Nina Sviridova, Tomoki Kurikawa, Nobuhiko Wagatsuma, Kazuyuki Aihara, Kazuyuki Aihara

“…In the present study, we aimed to investigate neuronal activity responsiveness with respect to the maturation of inhibition at gamma-band frequencies.MethodWe calculated inter-trial phase coherence (ITPC), which quantifies event-related phase modulations across trials, using a biologically plausible spiking neural network that generates gamma oscillations through interactions between excitatory and inhibitory neurons.ResultsOur results demonstrated that the neuronal response coherence to external periodic inputs exhibits an inverted U-shape with respect to the maturation of inhibition. …”
Get full text

The biogenesis, regulation and functions of transitive siRNA in plants by Tan Huijun, Liu Yuelin, Guo Hongwei

“…Small RNA (sRNA)-mediated RNA interference (RNAi) is a sequence-specific gene silencing mechanism that modulates gene expression in eukaryotes. …”
Get full text

Deep-Sea-Derived Isobisvertinol Targets TLR4 to Exhibit Neuroprotective Activity via Anti-Inflammatory and Ferroptosis-Inhibitory Effects by Zi-Han Xu, Ming-Min Xie, Chun-Lan Xie, Xian-Wen Yang, Jun-Song Wang

“…Additionally, <b>17</b> suppresses TLR4, reducing p38 MAPK phosphorylation, and inhibits ferroptosis by decreasing lipid peroxidation and modulating mitochondrial membrane potential. Metabolomic analysis showed that <b>17</b> rescues alterations in multiple metabolic pathways induced by RSL3 and increases levels of antioxidant metabolites, including glutamine, glutamate, and glutathione. …”
Get full text

Mesangial Cells Exhibit Features of Antigen-Presenting Cells and Activate CD4+ T Cell Responses by Hongyu Yu, Shaoyuan Cui, Yan Mei, Qinggang Li, Lingling Wu, Shuwei Duan, Guangyan Cai, Hanyu Zhu, Bo Fu, Li Zhang, Zhe Feng, Xiangmei Chen

“…Mesangial cells can present antigen and modulate CD4+ T lymphocyte proliferation and differentiation. …”
Get full text

Stepwise Adipogenesis of Decellularized Cellular Extracellular Matrix Regulates Adipose Tissue-Derived Stem Cell Migration and Differentiation by Ziang Zhang, Rongmei Qu, Tingyu Fan, Jun Ouyang, Feng Lu, Jingxing Dai

“…Microenvironmental factors can modulate the cellular status of adipose tissue-derived stem cells (ASCs). …”
Get full text

Edaphic factors mediate the response of nitrogen cycling and related enzymatic activities and functional genes to heavy metals: A review by Tracy Opande, Mengru Kong, Di Feng, YuHong Wen, Nathan Okoth, Ali Mohd Yatoo, Fatma Mohamed Ameen Khalil, Ahmed S. Elrys, Lei Meng, Jinbo Zhang

“…Environmental factors like soil organic carbon, soil texture, water content, temperature, soil pH, N fertilization, and redox status play significant roles in modulating the response of soil N cycling to HM contamination. …”
Get full text

Tailor-Made, Linear, and “Comb-Like” Polyester-Based Copolymers: Synthesis, Characterization, and Thermal Behavior of Potential 3D-Printing/Electrospinning Candidates by Franco L. Redondo, Mario D. Ninago, Augusto G. O. de Freitas, Cristiano Giacomelli, Andrés E. Ciolino, Marcelo A. Villar

“…All polymers exhibited narrow molar masses distributions (Mw/Mn<1.54), and their thermal properties were analyzed by isothermal crystallization kinetics (Avrami’s theory, by using differential scanning calorimetry (DSC)) and by employing modulated thermogravimetric analysis (MTGA). The macromolecular structure exerts a noticeable effect on the PCL block behavior when compared to the PCL homopolymer, at least for the temperature range studied (16–24°C): less differences in thermal properties were observed for linear block copolymers, whereas for “comb-like” graft copolymers their final crystallization capacity strongly depends on the presence of branches. …”
Get full text

The potential impact of glycine supplementation on the process of aging by Michalina Wójcikiewicz, Julia Kulbacka, Witold Czyż, Julia Kacperczyk, Karol Dziedzic, Marta Chuncia-Ileczko, Maciej Wojszczyk, Damian Zys, Piotr Pasek, Julia Ryniecka, Wiktor Czaja, Michał Krzciuk

“…Glycine, the simplest amino acid, has recently gained attention as a potential nutritional and therapeutic intervention to modulate various pathways implicated in aging. Beyond its structural role in collagen and other proteins, glycine is a critical precursor for glutathione- an essential intracellular antioxidant- plays a role in neurotransmission, and is involved in the synthesis of heme, creatine, and bile acids. …”
Get full text

Carrageenan-induced acute inflammation in the mouse air pouch synovial model. Role of tumour necrosis factor by M. Romano, R. Faggioni, M. Sironi, S. Sacco, B. Echtenacher, E. Di Santo, M. Salmona, P. Ghezzi

“…Carrageenan-induced inflammation was modulated by anti-inflammatory drugs. Pretreatment with dexamethasone (DEX) or indomethacin (INDO) inhibited cell migration and reduced the concentration of TNF in the exudate. …”
Get full text

Enhanced oracle bone corrosion detection using attention-guided YOLO with ghost convolution by Feng Gao, Ziheng Yang, Qiyu Liu, Zhan Zhang, Bang Li, Han Zhang

“…To tackle this challenge, this study incorporates advanced attention mechanisms, including Squeeze-and-Excitation Networks (SE), Coordinate attention, and Convolutional Block Attention Module (CBAM), into the YOLOv5 detection architecture. …”
Get full text