Ethylene vinyl acetate as a multifunctional compatibilizer for natural rubber/cis-1,4-polybutadiene rubber blends with enhanced compatibility, filler dispersion and mechanical prop... by Jiyu Liang, Jianhui Wu, Chunhua Wang, Jun Sang, Keshuai Ren, To Ngai, Wei Lin

“…Herein, we propose a facile approach to modulate the multi-scale structures in NR/BR blends including polymer compatibility and filler distribution by introducing ethylene vinyl acetate (EVA) with varying vinyl acetate (VA) content as multifunctional compatibilizers. …”
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Laryngeal cancer diagnosis based on improved YOLOv8 algorithm by Xin Nie, Xueyan Zhang, Di Wang, Yuankun Liu, Lumin Xing, Wenjian Liu

“…A novel multiscale enhanced convolution module has been introduced to improve the model’s feature extraction capabilities for small-sized targets. …”
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Railway Foreign Object Intrusion Detection Using UAV Images and YOLO-UAT by Yang Yang, Zhanhao Liu, Junming Chen, Haiming Gao, Tao Wang

“…Secondly, a C<inline-formula> <tex-math notation="LaTeX">$3\_$ </tex-math></inline-formula> CBAM module is constructed to enhance feature extraction and enhance the model&#x2019;s detection ability for small-scale targets. …”
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Q11, a CYP2E1 inhibitor, exerts anti-hepatocellular carcinoma effect by inhibiting M2 macrophage polarization by Cunzhen Zhang, Yan Fang, Mengxue Guo, Liming Tang, Yurong Xing, Jun Zhou, Yuanyuan Guo, Yuhan Gu, Qiang Wen, Na Gao, Haiwei Xu, Hailing Qiao

“…In summary, our findings suggest that Q11 could suppress M2 macrophage polarization by modulating the CYP2E1/( ±)9(10)-DiHOME or ( ±)12(13)-DiHOME/PPARγ axis, indicating that CYP2E1 may be a potential therapeutic target for HCC, and its inhibitor Q11 may be a potential drug for the treatment of HCC.…”
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PPARα: A Master Regulator of Bilirubin Homeostasis by Cyril Bigo, Jenny Kaeding, Diala El Husseini, Iwona Rudkowska, Mélanie Verreault, Marie Claude Vohl, Olivier Barbier

“…Hypolipidemic fibrates activate the peroxisome proliferator-activated receptor (PPAR) α to modulate lipid oxidation and metabolism. The present study aimed at evaluating how 3 PPARα agonists, namely, fenofibrate, gemfibrozil, and Wy14,643, affect bilirubin synthesis and metabolism. …”
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Targeted gut microbiome therapy: Applications and prospects of probiotics, fecal microbiota transplantation and natural products in the management of type 2 diabetes by Luqi Qin, Bei Fan, Yixia Zhou, Jiahuan Zheng, Rao Diao, Fengzhong Wang, Jiameng Liu

“…Additionally, it evaluates the potential of probiotics, fecal microbiota transplantation (FMT)/virome transplantation (FVT), and natural products in modulating gut microbiota to treat T2DM. Although existing studies have suggested that these interventions may delay or even halt the progression of T2DM, most research remained limited to animal models and observational clinical studies, with a lack of high-quality clinical data. …”
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Wogonin effects on the efflux transporters BCRP and MRP2, explain its effectiveness in ulcerative colitis: Implications for metabolic and transport interactions by Yuanyuan Liu, Zerong Zhang, Xiaoyan Li, Qinghong Hu, Zhangyu Jiang, Jia Lv, Jiayi Xue, Dongyu Wang, Jianxiong Cao, Lingyu Li, Xiaowen Ou, Lijun Zhu, Zhongqiu Liu, Tao Su

“…Interestingly, proteomic sequencing of mitochondrial subcellular organelles revealed that wogonin exhibited anti-UC effects by inhibiting afamin (AFM), with these effects modulated by BCRP and MRP2. These findings not only suggest a new mechanism for the anti-UC effects of wogonin, but also provide a pharmacological foundation for the clinical use of wogonin in treating UC.…”
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Ultrafast laser frequency tuning based on equivalent optical phase sampling and accumulation by Weiqiang Lyu, Huan Tian, Zhenwei Fu, Lingjie Zhang, Zhen Zeng, Yaowen Zhang, Heping Li, Zhiyao Zhang, Yong Liu

“…By inserting an electro-optic phase modulator (PM) into the laser cavity and properly setting the period of the driving signal applied to the PM to make its integer multiple slightly deviate from the round trip time of the laser cavity, a linear mapping from the voltage of the driving signal to the output laser frequency is realized via equivalent optical phase sampling and accumulation. …”
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Chitosan reduces naturally occurring plant pathogenic fungi and increases nematophagous fungus Purpureocillium in soil under field conditions by Raquel Lopez-Nuñez, Jorge Prieto-Rubio, Jorge Prieto-Rubio, Inmaculada Bautista, Antonio L. Lidón-Cerezuela, Miguel Valverde-Urrea, Federico Lopez-Moya, Luis V. Lopez-Llorca

“…Soil microbial network analysis for ITS2+V1–V2 regions revealed that the nematophagous fungus Pochonia promoted network clustering into modules. Furthermore, network analysis for ITS2+V3–V4 regions showed that the nematode trapping-fungus Orbilia and bacteria belonging to Acidimicrobiales and Cytophagales significantly contributed to network clustering in field soil. …”
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Overexpression of metalloproteinase PAPPA accelerates cancer progression and correlates with immune cell infiltration in gastric cancer: insights from bioinformatics and in vitro i... by Shiya Yu, Shiyao Zheng, Jinwei Qiu, Hongming Lin, Xiaojuan Yu, Huiyan Chen, Junhong Wu, Weihang Wu, Jiong Chen, Yongyuan Chen, Jianwei Chen, Hu Zhao, Yu Wang

“…Conclusions The findings of this investigation suggest that PAPPA serves as a crucial modulator of GC, underscoring its potential as a GC treatment target.…”
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n-3 Polyunsaturated Fatty Acid Supplementation Has No Effect on Postprandial Triglyceride-Rich Lipoprotein Kinetics in Men with Type 2 Diabetes by André J. Tremblay, Benoît Lamarche, Jean-Charles Hogue, Patrick Couture

“…Dietary n-3 polyunsaturated fatty acids (PUFAs) have been proposed to modulate plasma lipids, lipoprotein metabolism, and inflammatory state and to reduce triglyceride (TG) concentrations. …”
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Synergy Effects of the Indian Summer Monsoon and the Tibetan Plateau Heating on Summer Rainfall over North China by Siwen Zhao, Jie Zhang, Zhihong Lv

“…The summer rainfall over NC is therefore modulated by synergistic effect of both the ISM and TP heating.…”
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Kinetic investigation of the energy storage process in graphene fiber supercapacitors: Unraveling mechanisms, fabrications, property manipulation, and wearable applications by Juan Zhang, Wenwen Liu, Minzhi Du, Qingli Xu, Minren Hung, Ruifang Xiang, Meng Liao, Xinhou Wang, Bingjie Wang, Aiping Yu, Kun Zhang

“…Through theoretical analysis of the energy storage process, specific parameters in advanced GF fabrication methodologies are carefully summarized, which can be used to modulate nano/micro‐structures, thereby enhancing energy storage kinetics. …”
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Low-Dose Oxygen Enhances Macrophage-Derived Bacterial Clearance following Cigarette Smoke Exposure by William G. Bain, Ashutosh Tripathi, Pooja Mandke, Jonathan H. Gans, Franco R. D’Alessio, Venkataramana K. Sidhaye, Neil R. Aggarwal

“…Low-dose oxygen is a mainstay of therapy during COPD exacerbations; yet we understand little about whether oxygen can modulate the effects of cigarette smoke on lung immunity. …”
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Developing a Fire Monitoring System Based on MQTT, ESP-NOW, and a REM in Industrial Environments by Miracle Udurume, Taewoong Hwang, Raihan Uddin, Toufiq Aziz, Insoo Koo

“…Data collected by ESP32-CAM sensors, which are equipped with pre-trained YOLOv5-based fire detection modules, are processed and transmitted to a central monitoring server. …”
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The Study of Viral RNA Diversity in Bird Samples Using De Novo Designed Multiplex Genus-Specific Primer Panels by Andrey A. Ayginin, Ekaterina V. Pimkina, Alina D. Matsvay, Anna S. Speranskaya, Marina V. Safonova, Ekaterina A. Blinova, Ilya V. Artyushin, Vladimir G. Dedkov, German A. Shipulin, Kamil Khafizov

“…Since a reliable, bioinformatics-based analytical method for the rapid identification of the sequences was crucial, an NGS-based data analysis module was developed in this study, and its functionality in the detection of novel viruses and analysis of virome diversity was demonstrated.…”
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Successful Treatment of Tumor-Induced Osteomalacia by Multidisciplinary Therapy with Radiation to Intracranial Fibromyxoid Tumor by Mariangela Massaccesi, Francesco Miccichè, Mario Rigante, Gianluigi Petrone, Elisabetta Lepre, Maria Antonietta Gambacorta, Vincenzo Valentini

“…Starting from October 2015, external beam radiotherapy was delivered with a volumetric modulated arc technique to the tumor bed with a daily dose of 2 Gy up to a total dose of 60 Gy. …”
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Neuromodulation of Attentional Control in Major Depression: A Pilot DeepTMS Study by Jodie Naim-Feil, John L. Bradshaw, Dianne M. Sheppard, Oded Rosenberg, Yechiel Levkovitz, Pinhas Dannon, Paul B. Fitzgerald, Moshe Isserles, Abraham Zangen

“…Deep transcranial magnetic stimulation (deepTMS), a noninvasive neuromodulatory technique, can modulate neural activity and induce neuroplasticity changes in brain regions recruited by attentional processes. …”
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Gut Microbiota as Emerging Players in the Development of Alcohol-Related Liver Disease by Wei Li, Wenkang Gao, Shengqi Yan, Ling Yang, Qingjing Zhu, Huikuan Chu

“…The gut microbiota is speculated to trigger specific signaling pathways, influence metabolite profiles, and modulate immune responses in the gut and liver. This research aimed to investigate the role of gut microorganisms in the onset and advancement of alcohol-related liver disease, as well as to uncover the underlying mechanisms by which the gut microbiota may contribute to its development. …”
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A systematic review of Streptococcus Mutans and Veillonellae species interactions in dental caries progression: Positive or Negative impact? [version 1; peer review: 1 approved, 2... by Faizul Hasan, Prawati Nuraini, Ariadna Adisattya Djais, Ervina Restiwulan Winoto, Tantiana Tantiana, Rini Devijanti Ridwan, Juni Handajani, Rajesh Ramasamy, Silvia Anitasari, Hendrik Setia Budi

“…The findings suggest that Veillonellae spp. can modulate the acid production, and substrate competition of S. mutans, potentially influencing the cariogenic process.…”
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