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  1. 5681

    Therapeutic potential of SOX family transcription factors in osteoarthritis by Yue Huang, Zhuo Wang

    Published 2025-12-01
    “…Non-coding RNA may play a role in the onset and progression of osteoarthritis by modulating various SOX family members, including SOX2, SOX4, SOX5, SOX6, SOX8, SOX9 and SOX11.Conclusion SOX9 has the capability of mitigating the onset and progression of osteoarthritis through means such as medication therapy, stem cell therapy, recombinant adeno-associated virus (rAAV) vector therapy, physical therapy and other approaches.…”
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  2. 5682

    Online Learning as e-Learning: The Quality and Results (Critical Analysis) by A. V. Dozhdikov

    Published 2020-12-01
    “…To clarify the conditions of the transition and implementation of online technologies, it is proposed to hold a large-scale experiment with a randomly selection mechanisms for participants of training courses, instructors, disciplines (modules). The article focuses on the fact that while the impact of online education on the psychology and physiology of students has not been sufficiently studied, there is a risk of deteriorating health, as well as a drop in the quality of education. …”
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  3. 5683

    Color Alteration of Resin Composites by Cigarette Smoke with Various Levels of Tar, Nicotine, and Carbon Monoxide by Jéssica Dias Theobaldo, Waldemir Francisco Vieira-Junior, Marcela Alvarez Ferretti, Lorena Barros Costa, Giselle Maria Marchi, Debora Alves Nunes Leite Lima, Flávio Henrique Baggio Aguiar

    Published 2025-01-01
    “…Conclusion: Color alteration of resin composites was modulated by the cigarette and resin composite type, the NF resin composite being more susceptible to staining.…”
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  4. 5684

    Crane Lifting Optimization and Construction Monitoring in Steel Bridge Construction Project Based on BIM and UAV by Jiahao Tian, Sang Luo, Xinming Wang, Jing Hu, Jun Yin

    Published 2021-01-01
    “…Then, a fusion model which contains the lifting modules models, the as-is site model, and the crane model was gathered, based on which the collision detection was conducted by 4D crane operating path simulation. …”
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  5. 5685

    Role of Mitogen-Activated Protein Kinases in Myocardial Ischemia-Reperfusion Injury during Heart Transplantation by Giuseppe Vassalli, Giuseppina Milano, Tiziano Moccetti

    Published 2012-01-01
    “…Organ transplantation offers the opportunity of starting a preconditioning treatment before organ procurement or during cold storage, thus modulating early events in IR injury. Future studies will need to evaluate combined strategies including p38 MAPK and/or JNK inhibition, ERK1/2 activation, pre- or postconditioning protocols, new storage solutions, and gentle reperfusion.…”
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  6. 5686

    Caveolin-1 Scaffolding Domain Peptide Regulates Colon Endothelial Cell Survival through JNK Pathway by Kai Fang, Christopher G. Kevil

    Published 2020-01-01
    “…In this study, we examined how the antennapedia- (AP-) conjugated caveolin-1 scaffolding domain (AP-Cav) modulates vascular endothelial growth factor- (VEGF-) dependent colon endothelial cell angiogenic responses, as seen during colitis. …”
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  7. 5687

    Implementasi evaluasi model kirkpatrick terhadap kualitas sistem pembelajaran by Effendi M, Zainuddin Zainuddin, Muhammad Sabri Ahmad

    Published 2022-01-01
    “…Hasil dari  penelitian menunjukkan bahwa Pada Reaction Level, mahasiswa menunjukkan tingkat kepuasan atas kesesuaian materi dengan modul/BMP dan pelayanan administrasi di UT, namun merasa perlu perbaikan pada feedback tutor, keaktifan tutor dalam forum diskusi (tutorial online) dan lemahnya koneksi jaringan internet utamanya di Bobong. …”
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  8. 5688

    A study of serum prolactin in dermatological diseases in a tertiary care hospital of Assam by Talukdar C, Boro B

    Published 2024-10-01
    “…Background: Prolactin functions as a neuroendocrine modulator of the skin immune system and epithelial cell proliferation. …”
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  9. 5689

    Application and Analysis of an Ionic Liquid Gel in a Soft Robot by Chenghong Zhang, Bin He, Zhipeng Wang, Yanmin Zhou, Aiguo Ming

    Published 2019-01-01
    “…A soft robot was designed with the soft actuator as the basic module. The experimental results show that the ILG soft robot has good driving performance, and the soft robot can grab a 105 mg object at an input voltage of 3.5 V.…”
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  10. 5690

    Perception, Expectation, Affect, Analysis by Elizabeth Hellmuth Margulis

    Published 2013-01-01
    “…The account relies on previous empirical work establishing that topical context can modulate the kind of affect generated by a syntactic surprise. …”
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  11. 5691

    A UAV perspective based lightweight target detection and tracking algorithm for intelligent transportation by Quan Wang, Guangfei Ye, Qidong Chen, Songyang Zhang, Fengqing Wang

    Published 2024-12-01
    “…Furthermore, the C2f module is replaced by the FPW to reduce the pointless computation and memory utilization of the model. …”
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  12. 5692

    Neural progenitor cell-derived exosomes in ischemia/reperfusion injury in cardiomyoblasts by Oiva Arvola, Virpi Stigzelius, Minna Ampuja, Riikka Kivelä

    Published 2025-02-01
    “…In the adult human brain, vestigial neuronal progenitor stem cells contribute to neuronal repair and recovery following cerebral ischemic injury, an effect modulated by secreted exosomes. Ischemia conditioned neuronal cell derived supernatant and experimental stroke has been shown to be injurious to the heart. …”
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  13. 5693

    Dealing with post-excavation data: the Omeka S TiMMA web-database by Rueff, Bastien

    Published 2024-01-01
    “…Additionally, one of the successful achievements of this platform is to benefit the open-science tools more broadly, permitting for instance, as was done in this project, to import images with the iiiF API and bibliographical references with the Zotero module, thus avoiding the creation of new digital files and metadata. …”
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  14. 5694

    Effects of atractylodin and β-Eudesmol on P-glycoprotein and Caco-2 cells permeability by Artitaya Thiengsusuk, Wiriyaporn Sumsakul, Kesara Na–Bangchang

    Published 2025-02-01
    “…However, neither of the compounds were P-gp inhibitors nor modulators of the expression of MDR-1 mRNA, and P-gp function. …”
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  15. 5695

    The Effect of Long-Term Exercise on the Production of Osteoclastogenic and Antiosteoclastogenic Cytokines by Peripheral Blood Mononuclear Cells and on Serum Markers of Bone Metabol... by J. Kelly Smith, Rhesa Dykes, David S. Chi

    Published 2016-01-01
    “…Although it is recognized that the mechanical stresses associated with physical activity augment bone mineral density and improve bone quality, our understanding of how exercise modulates bone homeostasis at the molecular level is lacking. …”
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  16. 5696

    Chromosomes and speciation in tuco-tuco (Ctenomys, Hystricognathi, Rodentia) by A. A. Torgasheva, E. A. Basheva, M. J. Gomez Fernandez, P. Mirol, P. M. Borodin

    Published 2016-09-01
    “…Analysis of chromosome behavior in the meiotic prophase in the chromosomal heterozygotes revealed significant changes in the frequency and distribution of recombination: crossingover suppression around the breakpoint and chiasma distalization. These changes can modulate the flow of genes between chromosomal races and amplify the divergence which has arisen due to spatial isolation. …”
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  17. 5697
  18. 5698

    The relationship of lamins with epigenetic factors during aging by R. N. Mustafin, E. K. Khusnutdinova

    Published 2022-03-01
    “…This may be due to senile changes in the expression of lamins, which epigenetically modulate transposons. Lamins directly physically interact with transposons. …”
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  19. 5699

    Unraveling the Molecular Nexus between GPCRs, ERS, and EMT by Niti Kumari, Somrudee Reabroi, Brian J. North

    Published 2021-01-01
    “…These disturbances lead to the accumulation of misfolded proteins in the endoplasmic reticulum (ER) and induce a cellular condition called ER stress (ERS) which is counteracted by activation of the unfolded protein response (UPR). Many GPCRs modulate ERS and UPR signaling via ERS sensors, IRE1α, PERK, and ATF6, to support cancer cell survival and inhibit cell death. …”
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  20. 5700

    Transformer-Based Multi-Player Tracking and Skill Recognition Framework for Volleyball Analytics by Lei Jiang, Zhihong Yang, Lei Gang

    Published 2025-01-01
    “…Additionally, a transformer-based action recognition module identifies volleyball maneuvers, providing detailed analytics on player performance and behavior. …”
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