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5621
Circadian distribution of epileptiform discharges in epilepsy: Candidate mechanisms of variability.
Published 2023-10-01“…This model was extended to include a time-dependent forcing term, where the excitability of nodes within the network could be modulated by other factors. We calibrated this forcing term using independently-collected human cortisol (the primary stress-responsive hormone characterised by circadian and ultradian patterns of secretion) data and sleep-staged EEG from healthy human participants. …”
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5622
Adaptive backstepping control for electro-hydraulic servo system in extension sleeve press-fitting process of bearing pressing machine
Published 2025-01-01“…In the process of extension sleeve press-fitting of the bearing pressing machine, electro-hydraulic servo system of valve-controlled symmetrical cylinder (ESSVSC) is an important and critical control module, and its performance has a significant impact on the working accuracy of such equipment. …”
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5623
Impacts of tropical cyclones on extreme precipitation and flooding in a humid subtropical inland basin of China
Published 2025-02-01“…These influences were modulated by ENSO. In neutral years, the frequency and magnitude of TC-induced EPEs were greatest due to higher TC track density and frequency. …”
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5624
Targeting epithelial-mesenchymal transition signaling pathways with Dietary Phytocompounds and repurposed drug combinations for overcoming drug resistance in various cancers
Published 2025-02-01“…Thus, there is a need for medications that are both highly effective and with low cytotoxic for modulating EMT transitions at ground level. Thus, this led to the study of the evaluation and efficiency of phytochemicals found in dietary sources of fruits and vegetables and also the combination of small molecular repurposed drugs that can enhance the effectiveness of traditional cancer treatments. …”
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5625
Purinergic Receptors in Ocular Inflammation
Published 2014-01-01“…The nucleoside adenosine and nucleotides including adenine mononucleotides like ADP and ATP and dinucleotides such as P1,P4-diadenosine tetraphosphate (Ap4A), and P1,P5-diadenosine pentaphosphate (Ap5A) are present in different ocular locations and therefore they may contribute/modulate inflammatory processes. Adenosine receptors, in particular A2A adenosine receptors, present anti-inflammatory action in acute and chronic retinal inflammation. …”
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5626
“Energy for Free” in Resonance Electrical Circuits
Published 2024-01-01“…The circuit can power a controller module, and a step-down transformer. The performance scales with [Formula: see text], is weak for the 25-W PSU and improves with the increase in [Formula: see text]. …”
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5627
Development and laboratory evaluation of a novel IoT-based electric-driven metering system for high precision garlic planter.
Published 2025-01-01“…A combination of an infrared (IR) sensor, Arduino Mega board, stepper motor, speed sensor, and a Wi-Fi module was employed to operate the EDMS, as well as monitor and count the quantity of garlic seeds during the planting process and determine the qualified rate (QR) and missing rate (MR). …”
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5628
Sentimentally enhanced conversation recommender system
Published 2025-01-01“…Furthermore, the responses generated by the dialogue module are often monotonous, lacking diversity and expressiveness, and thus fall short of meeting the demands of complex scenarios. …”
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5629
Characterization of Chromatin Structure-associated Histone Modifications in Breast Cancer Cells
Published 2012-09-01“…Chromatin structure and dynamics that are influenced by epigenetic marks, such as histone modification and DNA methylation, play a crucial role in modulating gene transcription. To understand the relationship between histone modifications and regulatory elements in breast cancer cells, we compared our chromatin immunoprecipitation sequencing (ChIP-Seq) histone modification patterns for histone H3K4me1, H3K4me3, H3K9/16ac, and H3K27me3 in MCF-7 cells with publicly available formaldehyde-assisted isolation of regulatory elements (FAIRE)-chip signals in human chromosomes 8, 11, and 12, identified by a method called FAIRE. …”
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5630
Bone marrow mesenchymal stem cell‐derived exosomes improve renal fibrosis by reducing the polarisation of M1 and M2 macrophages through the activation of EP2 receptors
Published 2022-02-01“…Here, we investigate the therapeutic effect of BM‐MSCs on unilateral ureteral occlusion (UUO)‐induced interstitial fibrosis in the kidney by modulating prostaglandin E2 receptor 2 (EP2). Renal pathological changes were evident in the UUO group compared to the control group, with significantly increased expression of α‐smooth muscle actin (α‐SMA), fibronectin, Ep2 and F4/80+CD86+ and F4/80+CD206+ cells in the UUO group (p< 0.05). …”
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5631
The Effect of Transobturator Tape Surgery on Female Sexual Functions: A Systematic Review
Published 2020-08-01“…In total, 8 clinical studies employed female sexual function index whereas 8 clinical studies administered Prolapse/Urinary Incontinence Sexual Questionnaire -12. 4 of these studies tried to understand women’s sexual functions through questions determined by the researchers (N/A). 2 of the other studies used the Sexual Impact Questionnaire and a visual analogue scale, 1 study used Nine Questions on Sexual Functioning (NSF-9) and 1 study used International Consultation on Incontinence Questionnaire Vaginal Symptoms Module (ICIQ-VS). It was found that transobturator tape surgery that is performed for incontinence produces positive results on both sexual functions and urinary functions. …”
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5632
The Effect of Therapeutic Blockades of Dust Particles-Induced Ca2+ Signaling and Proinflammatory Cytokine IL-8 in Human Bronchial Epithelial Cells
Published 2015-01-01“…We investigated how to modulate dust particles-induced Ca2+ signaling and proinflammatory cytokine IL-8 expression. …”
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5633
An efficient and lightweight detection method for stranded elastic needle defects in complex industrial environments using VEE-YOLO
Published 2025-01-01“…Firstly, GSConv was introduced to enhance feature extraction in depthwise separable convolution and establish the VOVGSCSP module, emphasizing feature reusability for more effective feature engineering. …”
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5634
HDN-DDI: a novel framework for predicting drug-drug interactions using hierarchical molecular graphs and enhanced dual-view representation learning
Published 2025-01-01“…HDN-DDI integrates an explainable substructure extraction module to decompose drug molecules and represents them using innovative hierarchical molecular graphs, which effectively incorporates information from real chemical substructures and improves molecules encoding efficiency. …”
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5635
LINC00707 Regulates miR-382-5p/VEGFA Pathway to Enhance Cervical Cancer Progression
Published 2021-01-01“…Then, we predicted that LINC00707 could serve as a molecular sponge for miR-382-5p to modulate VEGFA expression in cervical cancer. Subsequently, lack of VEGFA expression reversed the influence of miR-382-5p knockdown on cervical cancer cells. …”
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5636
Network Pharmacology Analysis and Experimental Validation to Explore the Anti-inflammatory Mechanism of Asiatic Acid on Alcoholic Steatohepatitis
Published 2022-01-01“…This study provides multiple lines of evidence that asiatic acid may alleviate alcoholic hepatitis in mice by modulating the NF-κB pathway.…”
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5637
Smart Health Monitoring and Management System for Organizations Using Radio-Frequency Identification (RFID) Technology in Hospitals or Emergency Applications
Published 2022-01-01“…Because the proposed solution is based on mature existing hardware modules and software packages, any experienced information technology professional can quickly build an analogous monitoring and management system by following the instructions presented in this paper.…”
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5638
AFF-LightNet: A Lightweight Ship Detection Architecture Based on Attentional Feature Fusion
Published 2024-12-01“…To enhance the fusion of multi-scale features and semantically inconsistent features, we introduce iterative attentional feature fusion (IAFF) into the proposed neck network, improving the efficiency of feature fusion by introducing a multi-scale channel attention module. Also, deep and cross network version 2 (DCNv2) is replaced by Convolution (Conv) in the backbone network to further improve the detection accuracy of the proposed network. …”
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5639
Advancing Neuroscience and Therapy: Insights into Genetic and Non-Genetic Neuromodulation Approaches
Published 2025-01-01“…By systematically evaluating the principles, mechanisms, advantages, limitations, and efficacy in modulating neuronal activity and the potential applications in interventions of neurological disorders of these neuromodulation techniques, a comprehensive picture is gradually emerging regarding the advantages and challenges of neuromodulation techniques, their developmental trajectory, and their potential clinical applications. …”
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5640
Luteolin ameliorates rat model of metabolic syndrome-induced cardiac injury by apoptosis suppression and autophagy promotion via NR4A2/p53 regulation
Published 2025-01-01“…It is documented that the nuclear receptor 4A2 (NR4A2) could modulate autophagy and apoptosis in cardiac complications. …”
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