RIOK1/2 Negatively Regulates the Antiviral Response by Targeting TBK1 in Yellow Catfish (<i>Pelteobagrus fulvidraco</i>) by Kejun Liu, Jiayang Huang, Yuting Gui, Qian Li, Lei Zhang, Shuting Xiong

“…Here, we investigated the roles of yellow catfish RIO kinases, PfRIOK1 and PfRIOK2, in modulating the IFN response through their interaction with PfTBK1, a key player in the RLR signaling pathway. …”
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Dark-field X-ray microscopy with structured illumination for three-dimensional imaging by Doğa Gürsoy, Kaan Alp Yay, Elliot Kisiel, Michael Wojcik, Dina Sheyfer, Arndt Last, Matthew Highland, Ian Randal Fisher, Stephan Hruszkewycz, Zahir Islam

“…Our approach employs a coded aperture to spatially modulate the incident X-ray beam, enabling 3D structural reconstruction from images captured at various aperture positions. …”
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Consumption of a High-Fat Diet Alters Perineuronal Nets in the Prefrontal Cortex by P. M. Dingess, J. H. Harkness, M. Slaker, Z. Zhang, S. S. Wulff, B. A. Sorg, T. E. Brown

“…PNNs contribute to synaptic stabilization, protect against oxidative stress, regulate the ionic microenvironment within cells, and modulate regional excitatory output. To examine diet-induced changes in PNNs, we maintained rats on one of three dietary conditions for 21 days: ad libitum chow, ad libitum 60% high fat (HF-AL), or limited-access calorically matched high fat (HF-CM), which produced no significant change in weight gain or adiposity with respect to chow controls. …”
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Effects of Lactiplantibacillus plantarum HNU082 intervention on fungi and bacteriophages in different intestinal segments of mice by Xinlei Liu, Zhe Han, Wenyao Ma, Weipeng Cui, Dongyu Zhen, Shuaiming Jiang, Jiachao Zhang

“…Probiotics substantially influence gut fungi and bacteriophages, modulating their composition through both direct and indirect mechanisms, thereby influencing host health. …”
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Ribosomal proteins mediate non-canonical regulation of gut inflammatory signature by crop contaminant deoxynivalenol by Juil Kim, BoGyoung Song, Ki-Hyung Kim, Yuseok Moon

“…These insights provide potential molecular targets for therapeutic intervention in toxin-induced inflammatory diseases of the gut, highlighting the non-canonical roles of ribosomal proteins in modulating immune responses to environmental stressors.…”
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Recent advances in bacterial outer membrane vesicles: Effects on the immune system, mechanisms and their usage for tumor treatment by Shuo Xiang, Qiufang Yao, Arshad Khan, Dong Wang

“…Bacteria inherently possess motility, allowing them to preferentially colonize tumors and modulate the tumor immune microenvironment, thus influencing the efficacy of immunotherapy. …”
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Lipid Nanoparticles With Fine‐Tuned Composition Show Enhanced Colon Targeting as a Platform for mRNA Therapeutics by Riccardo Rampado, Gonna Somu Naidu, Olga Karpov, Meir Goldsmith, Preeti Sharma, Assaf Ezra, Lior Stotsky, Dor Breier, Dan Peer

“…These efforts focus mainly on the tolerability and transfectability of new ionizable lipids and RNAs, or modulating LNPs biodistribution with active targeting strategies. …”
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Evaluating the effects of seed oils on lipid profile, inflammatory and oxidative markers, and glycemic control of diabetic and dyslipidemic patients: a systematic review of clinica... by Lucas Fornari Laurindo, Lucas Fornari Laurindo, Lucas Fornari Laurindo, Lívia Fornari Laurindo, Victória Dogani Rodrigues, Jéssica da Silva Camarinha Oliveira, Beatriz Leme Boaro, Adriano Cressoni Araújo, Adriano Cressoni Araújo, Elen Landgraf Guiguer, Elen Landgraf Guiguer, Elen Landgraf Guiguer, Claudia Rucco Penteado Detregiachi, Claudia Rucco Penteado Detregiachi, Virgínia Maria Cavallari Strozze Catharin, Virgínia Maria Cavallari Strozze Catharin, Eduardo Federighi Baisi Chagas, Eduardo Federighi Baisi Chagas, Vitor Cavallari Strozze Catharin, Vitor Cavallari Strozze Catharin, Rosa Direito, Sandra Maria Barbalho, Sandra Maria Barbalho, Sandra Maria Barbalho, Sandra Maria Barbalho

“…The review included 11 studies demonstrating that seed oils derived from canola, flaxseed, and sesame seeds can positively influence lipid profiles and glycemic control while potentially modulating oxidative stress markers. The findings suggest that seed oils may benefit in managing diabetes and dyslipidemia, although the results are sometimes inconsistent. …”
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Detector development for spin-echo SANS techniques using ZnS:Ag/6LiF and 6Li glass scintillators by Giacomo Mauri, G. Jeff Sykora, Gregory N. Smith, Steven R. Parnell, Robert M. Dalgliesh, Dirk Honecker, Sarah E. Mann, Erik M. Schooneveld, Nigel J. Rhodes

“…The Larmor instrument at ISIS is equipped to operate in spin-echo modulated SANS (SEMSANS) and spin-echo SANS (SESANS) mode. …”
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MD-Unet for tobacco leaf disease spot segmentation based on multi-scale residual dilated convolutions by Zili Chen, Yilong Peng, Jiadong Jiao, Aiguo Wang, Laigang Wang, Wei Lin, Yan Guo

“…Building upon the Unet architecture, we developed the Multi-scale Residual Dilated Segmentation Model (MD-Unet) by enhancing the feature extraction module and integrating attention mechanisms. The results demonstrated that MD-Unet achieved 92.75%, 90.94%, 84.93%, and 91.81% for the lesion CPA, recall, IoU, and F1 metrics, respectively, with an overall Dice score of 94.67%. …”
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Regulatory role of S1P and its receptors in sepsis-induced liver injury by Bin Wang, Bin Wang, Xiaoyu Wu, Xiaoyu Wu, Jiangfeng Cheng, Jiangfeng Cheng, Junming Ye, Junming Ye, Hongquan Zhu, Hongquan Zhu, Xiaofeng Liu, Xiaofeng Liu

“…This paper focused on the mechanistic pathways through which S1P and its receptors modulate immunity, bile acid metabolism, and liver-intestinal circulation in septic liver injury. …”
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HandSegNet: Hand segmentation using convolutional neural network for contactless palmprint recognition by Koichi Ito, Yusei Suzuki, Hiroya Kawai, Takafumi Aoki, Masakazu Fujio, Yosuke Kaga, Kenta Takahashi

“…HandSegNet employs a new CNN architecture consisting of an encoder–decoder model with a pyramid pooling module. Through performance evaluation using a set of synthesised hand images, HandSegNet exhibited the best segmentation results of 98.90% and 93.20% for accuracy and intersection over union, respectively. …”
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Aircraft Detection for Remote Sensing Images Based on Deep Convolutional Neural Networks by Liming Zhou, Haoxin Yan, Yingzi Shan, Chang Zheng, Yang Liu, Xianyu Zuo, Baojun Qiao

“…With the intention to resist the background noise, this paper proposes the Deeper and Wider Module (DAWM) which increases the perceptual field of the network to alleviate the affection. …”
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Simulation of Flow-Induced Vibration and Dynamic Performance of Circular-Arc Helical Gear Pump under Background of Machine Learning by Xiaoling Wei, Yongbao Feng, Xiaoxia Han, Zhenxin He

“…The numerical calculation part of the acoustics in this paper is solved by the hybrid method, and the flow field is discretely calculated by the large eddy simulation (LES) module in the Fluent software. When the calculated flow field is stable, the velocity field of one impeller rotation period is selected to be output as the iterative value of the sound field and imported into ACTRAN for Fourier transform. …”
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A Single Bout of Fasting (24 h) Reduces Basal Cytokine Expression and Minimally Impacts the Sterile Inflammatory Response in the White Adipose Tissue of Normal Weight F344 Rats by Kristin J. Speaker, Madeline M. Paton, Stewart S. Cox, Monika Fleshner

“…The following experiment tested if a 24 h fast would modulate basal and stress-evoked sterile inflammation in plasma and adipose. …”
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Applying Machine Learning Techniques to Identify Undiagnosed Patients with Exocrine Pancreatic Insufficiency by Bruce Pyenson, Maggie Alston, Jeffrey Gomberg, Feng Han, Nikhil Khandelwal, Motoharu Dei, Monica Son, Jaime Vora

“…**Methods:** A machine learning algorithm was developed in Scikit-learn, a Python module. The study population, selected from the 2014 Truven MarketScan® Commercial Claims Database, consisted of patients with EPI-prone conditions. …”
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Using insecticidal compounds to elucidate the potential role of neurotransmitters in Lepidoptera pupal ecdysis by Niranjana Krishnan, Cassandra Gorman, Jillian Stewart, Steven Bradbury, Russell Jurenka

“…Since neonicotinoids disrupt acetylcholine signaling, we hypothesized that the excitatory neurotransmitter acetylcholine plays a critical role in regulation of pupal ecdysis, likely by modulating the release of peptides from crustacean cardioactive peptide (CCAP) neurons. …”
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Influencing Factors of Disturbance Effects of Blasting and Driving of Deep Mine Roadway Groups by Jiaguang Kan, Peng Wang, Peng Wang

“…We use the dynamic analysis module in FLAC3D to obtain the influence laws of three factors on the disturbance effects of adjacent roadways, namely, excavation methods, layer position changes of the roadway group, and whether or not bolt support is applied in the first roadway. …”
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Effect of Probiotics and Herbal Products on Intestinal Histomorphological and Immunological Development in Piglets by Daiga Gāliņa, Līga Ansonska, Anda Valdovska

“…It suggests that probiotics and herbs had influence on the intestinal histomorphology and the ability to modulate the mucosal immune system; however, the combination of probiotics and buckwheat bran was not so convincing, probably due to the inhibitory effect of the buckwheat bran on the probiotics used.…”
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Unlocking prognostic potential: A genomic signature of caloric restriction in patients with epithelial ovarian cancer. by Ori Tal, Tamar Zahavi, Liat Anabel Sinberger, Mali Salmon-Divon

“…<h4>Methods</h4>We conducted a literature search to identify proteins modulated by fasting, intermittent fasting or prolonged caloric restriction in human females. …”
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