LUneXt: Simple and Efficient U-shaped Network Design for Medical Image Segmentation with Nonlinear Activation by Guanghong Deng, Bing Yu, Wenlong Jing, Yong Li, Xiaodan Zhao

“…Both normalized activations for the original negative input image activation have good optimization capabilities for the tokenization module parameters proposed in the original UneXt model. …”
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Trehalose enhances macrophage autophagy to promote myelin debris clearance after spinal cord injury by Zhida Ma, Congpeng Meng, Xiang Wang, Yuanzhe Zhao, Jingwen Wang, Yihao Chen, Yiteng Li, Yan Jiang, Fangru Ouyang, Jianjian Li, Meige Zheng, Li Cheng, Juehua Jing

“…Conclusions Our findings underscore the pivotal role of trehalose in modulating myelin debris clearance within macrophages, providing new perspectives for the treatment of spinal cord injury. …”
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Nanoparticle-Based Rice Husk Liquid Smoke as Periodontitis Therapy through OPG, RANK, and RANKL Expression by Ira Arundina, Theresia Indah Budhy, Aqsa Sjuhada Oki, Meircurius Dwi Condro Surboyo, Arvind Babu Rajendra Santosh, null Sidarningsih, Indeswati Diyatri, Tytania Rahmaputry, Arya Pradana, Mohammad Iqbal, Azzahra Salsabila Adira Moelyanto

“…Nanostructured liquid smoke derived from rice husk nanoparticles (n-RHLS) demonstrates potential as a therapeutic agent for periodontitis, especially on OPG/RANK/RANKL expression, by modulating OPG and RANKL expression to support periodontal tissue health.…”
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High-Energy Burst-Mode 3.5 μm MIR KTA-OPO by Haowen Guo, Chunyan Jia, Shuai Ye, Yongping Yao, Tiejun Ma, Jiayu Zhang, Meng Bai, Jinbao Xia, Hongkun Nie, Bo Yao, Jingliang He, Baitao Zhang

“…Utilizing a quasi-continuous wave (QCW) laser diode (LD) side-pump module and electro-optic (EO) Q-switching technique, a high beam quality 1064 nm burst-mode laser was achieved as the fundamental source, generating 30 mJ high-energy pulses at burst repetition rates of 100 Hz and 200 Hz with sub-burst repetition rates of 20 kHz, 40 kHz, and 50 kHz. …”
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Model-enhanced spatial-temporal attention networks for traffic density prediction by Qi Guo, Qi Tan, Yue Peng, Long Xiao, Miao Liu, Benyun Shi

“…Furthermore, this paper utilizes the attention mechanism to dynamically model spatial-temporal dependencies, capturing real-time traffic conditions and density, and constructs a spatial-temporal attention module for learning. To validate the performance of the proposed MSTAN model, experiments are conducted on two public datasets of California highways (PeMS04 and PeMS08). …”
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Land drainage functioning and hydrological impacts in rural catchments: model development and field experiments by Zimmer, Daniel, Tournebize, Julien, Bouarfa, Sami, Kao, Cyril, Lesaffre, Benoît

“…The SIDRA model also includes a surface runoff module and has been coupled to different modelling tools and used to analyse the impacts of subsurface drainage on water quality. …”
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Bridging the Gap: Interventions to Increase Cancer Screening Adherence in Individuals with Mental Disorders—A Systematic Review by Paolo Lombardo, Ilaria Mussetto, Valentina Baccolini, Enrico Di Rosa, Alessandra Sinopoli

“…The proposed interventions included patient navigation, case management, and support from staff members along with educational modules, decision counselling sessions, and enhanced primary care. …”
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Engineering Magnetic Heterostructures with Synergistic Regulation of Charge‐Transfer and Spin‐Ordering for Enhanced Water Oxidation by Chongyan Hao, Yang Wu, Xiaobo Zheng, Yumeng Du, Yameng Fan, Weikong Pang, Anton Tadich, Shujun Zhang, Thomas Frauenheim, Tianyi Ma, Xiaoning Li, Zhenxiang Cheng

“…In this study, a novel magnetic heterostructure, CoFe2O4@CoFeMo3O8, is designed to simultaneously modulate charge and spin characteristics, and systematically elucidated their synergistic impact on the oxygen evolution reaction (OER). …”
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Graphene-Based, Flexible, Wearable Piezoresistive Sensors with High Sensitivity for Tiny Pressure Detection by Rui Li, Jiahao Hu, Yalong Li, Yi Huang, Lin Wang, Mohan Huang, Zhikun Wang, Junlang Chen, Yan Fan, Liang Chen

“…The piezoresistive performance of the sensor can be modulated by controlling the size of the PS microspheres and doping degree of the copper nanoparticles. …”
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AMPK: An energy sensor for non-small cell lung cancer progression and treatment by Zhi-Ting Zhong, Xu-Yan Wang, Ying Pan, Ke Zhou, Jing-Hui Chen, Yu-Qi Gao, Bo Dai, Zhi-Ling Zhou, Rui-Qi Wang

“…Secondly, we summarise the drugs and related substances that modulate the AMPK signalling pathway in NSCLC and evaluate the evidence from preclinical studies on combination AMPK-targeted therapies to address the issue of drug resistance in NSCLC under current clinical treatments. …”
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The roles of pleiotrophin in brain injuries: a narrative review of the literature by Yupeng Lei, Ruixi Zhou, Qian Mao, Xia Qiu, Dezhi Mu

“…Recently, many studies have indicated that PTN participates in the development of brain and plays a neuroprotection after brain injury, especially promoting neuronal survival and neurite outgrowth, stimulating oligodendrocyte maturation and myelination, modulating neuroinflammation, and so on.Objective However, no reviews comprehensively summarize the roles of PTN in brain injuries. …”
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Sarcoidosis: molecular mechanisms and therapeutic strategies by Danfeng Xu, Xiaohua Tao, Yibin Fan, Yan Teng

“…CD4 + T cells initiate dysregulated immune responses and secrete significant quantities of inflammatory cytokines, including interleukin (IL)-2 and interferon-gamma (IFN-γ), which play a crucial role in modulating the aggregation and fusion of macrophages to form granulomas. …”
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Efficacy of a guided internet-based intervention (iSOMA) for somatic symptoms and related distress in university students: study protocol of a randomised controlled trial by Harald Baumeister, Michael Witthöft, Eileen Bendig, Severin Hennemann, Katja Böhme, Maria Kleinstäuber, David Daniel Ebert

“…The planned study aims to investigate the feasibility and efficacy of an internet-based intervention in reducing somatic and psychological symptoms in an international population of university students with somatic symptom burden.Methods and analysis This parallel two-armed randomised controlled trial evaluates an 8-week guided intervention, including web-based consecutive modules based on cognitive behavioural therapy (CBT) principles against a waitlist control group. …”
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Effect of Mechanical Force Stress on the Inflammatory Response in Human Periodontal Ligament Cells by Thira Rojasawasthien, Supreda Suphanantachat Srithanyarat, Wajathip Bulanawichit, Thanaphum Osathanon

“…Additionally, we underscore the involvement of toll-like receptors (TLRs), particularly TLR4, in transducing mechanical stress signals and modulating cytokine production. This review demonstrates that hPDLSCs respond to different mechanical forces with specific gene expression changes that direct inflammatory and bone remodelling signals, leading to increased osteoblast and osteoclast activity. …”
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Numerical Simulation of Thermo-Hydro-Mechanical Coupling of Model Test for Nuclear Waste Disposal by Yu-Ping Wang, Zhe Wang, Fa-Cheng Yi, Lei Fu, Ying Luo

“…Using the buffer material Mock-up test of multi-field coupling as a model, the partial differential equation (PDE) module in the general finite element software COMSOL Multiphysics was developed by a second development stage. …”
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Statins Increase the Frequency of Circulating CD4+FOXP3+ Regulatory T Cells in Healthy Individuals by Ana Lucía Rodríguez-Perea, Carlos J. Montoya, Sven Olek, Claire A. Chougnet, Paula A. Velilla

“…Statins have been shown to modulate the number and the suppressive function of CD4+FOXP3+ T cells (Treg) in inflammatory conditions. …”
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Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures by Natalia Malek, Katarzyna Popiolek-Barczyk, Joanna Mika, Barbara Przewlocka, Katarzyna Starowicz

“…Anandamide as an immune modulator in the central nervous system acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55). …”
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Conventional and complementary alternative medicine therapies for renal anemia: a literature review by Ching-Ming Lu, Ching-Ming Lu, Yuan-Hsuan Hsu, Yuan-Hsuan Hsu, I-Hsin Lin, Ko-Lin Kuo, Jian-Fu Liao, Hui-Fen Huang, Hui-Fen Huang, Ping-Hsun Lu, Ping-Hsun Lu

“…The article details the effects of Roxadustat, Ferumoxytol, and Epodion.Clinical studies show that modulating the gut microbiome can reduce inflammation and improve renal anemia. …”
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Altered cortical network dynamics during observing and preparing action in patients with corticobasal syndrome by Marius Krösche, Christian J. Hartmann, Markus Butz, Alfons Schnitzler, Jan Hirschmann

“…We analyzed spectral power modulations at the source level.During action observation, event-related beta power (13-30 Hz) suppression was weaker in CBS patients compared to controls. …”
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Future increase in compound soil drought-heat extremes exacerbated by vegetation greening by Jun Li, Yao Zhang, Emanuele Bevacqua, Jakob Zscheischler, Trevor F. Keenan, Xu Lian, Sha Zhou, Hongying Zhang, Mingzhu He, Shilong Piao

“…Abstract Compound soil drought and heat extremes are expected to occur more frequently with global warming, causing wide-ranging socio-ecological repercussions. Vegetation modulates air temperature and soil moisture through biophysical processes, thereby influencing the occurrence of such extremes. …”
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