Prolactin Is a Strong Candidate for the Regulation of Luteal Steroidogenesis in Vizcachas (Lagostomus maximus) by S. Proietto, S. A. Cortasa, M. C. Corso, P. I. F. Inserra, S. E. Charif, A. R. Schmidt, N. P. Di Giorgio, V. Lux-Lantos, A. D. Vitullo, V. B. Dorfman, J. Halperin

“…In conclusion, both the PRLR and LHR expressions in the ovary would define the success of gestation in vizcachas by modulating the levels of 20α-HSD and 3ß-HSD, which ultimately determine the level of serum P4 throughout gestation.…”
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PPARα Is Required for PPARδ Action in Regulation of Body Weight and Hepatic Steatosis in Mice by Wojciech G. Garbacz, Jeffrey T. J. Huang, Larry G. Higgins, Walter Wahli, Colin N. A. Palmer

“…Also the levels of the PPARα endogenous agonist 16:0/18:1-GPC were shown to be modulated by PPARδ in wild type mice. Our results show that both PPARδ and PPARα receptors are essential for GW501516-driven adipose tissue reduction and subsequently hepatic steatosis, with PPARα working downstream of PPARδ.…”
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The Nrf-2/HO-1 Signaling Axis: A Ray of Hope in Cardiovascular Diseases by Xueyan Zhang, Yihan Yu, Hanyu Lei, Yufeng Cai, Jie Shen, Ping Zhu, Qingnan He, Mingyi Zhao

“…Nrf2/HO-1 also has the ability to modulate calcium levels to prevent ferroptosis, pyroptosis, autophagy, programmed cell necrosis, alkaliptosis, and clockophagy. …”
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Inhibitory Effect on Cerebral Inflammatory Response following Traumatic Brain Injury in Rats: A Potential Neuroprotective Mechanism of N-Acetylcysteine by Gang Chen, Jixin Shi, Zhigang Hu, Chunhua Hang

“…However, it has not been investigated whether NAC modulates TBI-induced cerebral inflammatory response. …”
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Neuroplasticity of Acupuncture for Stroke: An Evidence-Based Review of MRI by Jinhuan Zhang, Chunjian Lu, Xiaoxiong Wu, Dehui Nie, Haibo Yu

“…In addition, acupuncture therapy can modulate the function and structural plasticity of post-stroke, which may be linked to the mechanism effect of acupuncture.…”
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Semantic Modeling for SNPs Associated with Ethnic Disparities in HapMap Samples by HyoYoung Kim, Won Gi Yoo, Junhyung Park, Heebal Kim, Byeong-Chul Kang

“…A semantic network is needed for in-depth understanding of the impacts of SNPs, because phenotypes are modulated by complex networks, including biochemical and physiological pathways. …”
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Virtual screening and molecular docking of Indonesian phytoconstituents as potential inhibitors of peroxisome proliferator-activated receptor gamma in polycystic ovary syndrome by Tunjungseto Arif, Iffatunnisa Fakhriyah, Pratiwi Intan Winta, Alif Azzam Muhyiddin Afrizal, Ahsan Fadhil, Santoso Budi

“…Peroxisome proliferator-activated receptor-gamma (PPARG) is one of the essential modulators of ovarian steroid hormone synthesis and lipid metabolism. …”
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Tofacitinib and budesonide treatment affect stemness and chemokine release in IBD patient-derived colonoids by Arun Sridhar, Ingunn Bakke, Shreya Gopalakrishnan, Nimo Mukhtar Mohamud Osoble, Emilie Prytz Hammarqvist, Henrik P. Sahlin Pettersen, Arne Kristian Sandvik, Ann Elisabet Østvik, Marianne Doré Hansen, Torunn Bruland

“…However, the impact of immune cell-modulating IBD drugs on epithelial homeostasis and repair is poorly understood. …”
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MCL Plays an Anti-Inflammatory Role in Mycobacterium tuberculosis-Induced Immune Response by Inhibiting NF-κB and NLRP3 Inflammasome Activation by Qingwen Zhang, Xinru Jiang, Weigang He, Kailin Wei, Jinxia Sun, Xiangyang Qin, Yuejuan Zheng, Xin Jiang

“…According to our results, MCL plays an important role in modulating Mtb-induced inflammatory response through PI3K/Akt/NF-κB pathway and subsequently downregulating the activation of NLRP3 inflammasome. …”
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Leptin Antagonizes Peroxisome Proliferator-Activated Receptor-γ Signaling in Growth Plate Chondrocytes by Lai Wang, Yvonne Y. Shao, R. Tracy Ballock

“…Furthermore, leptin signaling in growth plate cells is also negatively modulated by activation of PPARγ, implying that these two signaling pathways are mutually regulated in growth plate chondrocytes.…”
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Microstructure Characterisation and Modelling of Pre-Forging Solution Treatment of 7075 Aluminium Alloy Using Novel Heating Methods by Hao Wu, Zisong Lu, Steven Hill, Richard Turner

“…This study evaluates the effectiveness of these conventional heating methods, commonly adopted in the industry with long durations (typically one hour), in comparison to newer, potentially more efficient approaches such as induction coil heating, infrared module heating, and infrared furnaces that can perform solution heat treatment in significantly shorter times (5 to 20 min). …”
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How to increase value and reduce waste in research: initial experiences of applying Lean thinking and visual management in research leadership by Annmarie Touborg Lassen, Jesper Ryg, Torben Knudsen, Vibeke Andersen, Torkell Ellingsen, Mohammad Naghavi-Behzad, Anna-Marie Bloch Münster, Aleksander Krag, Tahir Masud, Oke Gerke, Kim Brixen, Kirsten Kyvik, Kristian Kidholm, Malene Grubbe Hildebrandt, Jørgen Ejler Pedersen, Henrik J Ditzel, Annette Langhoff, Gert Nielsen

“…The leaders of the research units were instructed in Lean thinking and Lean methods during a five-module course focusing on increasing value and reducing waste in research production. …”
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PGC1α Activators Mitigate Diabetic Tubulopathy by Improving Mitochondrial Dynamics and Quality Control by So-Young Lee, Jun Mo Kang, Dong-Jin Kim, Seon Hwa Park, Hye Yun Jeong, Yu Ho Lee, Yang Gyun Kim, Dong Ho Yang, Sang Ho Lee

“…Our results demonstrate that increases in PGC1α activity improve diabetic tubulopathy by modulating mitochondrial dynamics and autophagy.…”
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DiffRSS: A Diffusion-Guided Multi-Scale Features Remote Sensing Image Segmentation Method by Honghao Liu, Ruixia Yang, Yue Xu, Zhengchao Chen, Yuyang Zheng

“…We conceptualize the semantic segmentation of remote sensing images as a conditional generation task and design a Multiscale Cyclic Denoising Module (MSCDM), which effectively leverages multiscale features of remote sensing images, leading to superior segmentation outcomes. …”
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Role of aquaporins in brain water transport and edema by Yuyuan Li, Yining Wang, Xingda Huang, Hao Zhang, Youfei Guan, Xiaoyan Zhang

“…There is an urgent need to develop specific AQP inhibitors and activators to explore the potential benefits of modulating the functions of AQP1 and AQP4 in the context of brain edema.…”
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Ataxin-10 Inhibits TNF-α-Induced Endothelial Inflammation via Suppressing Interferon Regulatory Factor-1 by Yong Li, Qi Zhang, Na Li, Liting Ding, Jinping Yi, Yue Xiao, Shibiao Chen, Xuan Huang

“…Here, we identify Ataxin-10 protein as a novel negative modulator of endothelial activation by suppressing IRF-1 transcription activity. …”
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Protein and metabolite acclimations to temperature variability in a calcareous green macroalga Halimeda macroloba by Hao Zhang, Yuyu Wang, Lingshuai Zhang, Zhiqin Wang, Zejun Zhu, Lijuan Long, Lijuan Long

“…At the sub-optimal temperature of 25°C, the alga modulated its fatty acid composition to maintain membrane fluidity and accumulated selenium-containing metabolites to mitigate oxidative stress. …”
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N7-methylguanosine modification in cancers: from mechanisms to therapeutic potential by Qihui Wu, Xiaodan Fu, Guoqian Liu, Xiaoyun He, Yimin Li, Chunlin Ou

“…On one hand, m7G modification-associated modulate tumour progression and affect malignant biological characteristics, including sustained proliferation signalling, resistance to cell death, activation of invasion and metastasis, reprogramming of energy metabolism, genome instability, and immune evasion. …”
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Snoezelen or Controlled Multisensory Stimulation. Treatment Aspects from Israel by Joav Merrick, Carmit Cahana, Meir Lotan, Isack Kandel, Eli Carmeli

“…Snoezelen has proved to be an important instrument and a powerful therapeutic tool among the various treatment modules employed in Israel for persons with ID. This paper presents the concept illustrated with two case stories.…”
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Progesterone Changes the Pregnancy-Induced Adaptation of Cardiomyocyte Kv2.1 Channels via MicroRNA-29b by Shuang Liang, Yu-Shuang Sun, Lu Li, Yao Long, Meng Wang, Hou-Zhi Yang, Chun-Di Li, Yan Wang, Shan-Shan Li, Xu Chen, Xin Jin

“…Our data showed that P4 modulated maternal cardiac repolarization by regulating Kv2.1 channel activity during pregnancy. …”
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