Peroxisome Proliferator-Activated Receptor γ Induces the Expression of Tissue Factor Pathway Inhibitor-1 (TFPI-1) in Human Macrophages by G. Chinetti-Gbaguidi, C. Copin, B. Derudas, N. Marx, J. Eechkoute, B. Staels

“…However, whether PPARγ activation modulates the expression of TFP1-1 in human macrophages is not known. …”
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Anti-Inflammatory Strategy for M2 Microglial Polarization Using Retinoic Acid-Loaded Nanoparticles by Marta Machado-Pereira, Tiago Santos, Lino Ferreira, Liliana Bernardino, Raquel Ferreira

“…Herein, we propose the use of retinoic acid-loaded polymeric nanoparticles (RA-NP) as a means to modulate microglia response towards an anti-inflammatory and neuroprotective phenotype (M2). …”
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Environment-Aware CMT for Efficient Video Delivery in Wireless Multimedia Sensor Networks by Yuanlong Cao, Changqiao Xu, Jianfeng Guan, Fei Song, Hongke Zhang

“…The e -CMT provides environment-aware cognitive ability for efficient video delivery with three modules, which are Path Quality-aware Model (PQM) that devotes to estimate path quality and select candidate path using for retransmission, Adaptive Retransmission Trigger (ART) that contributes to cognize packet loss and trigger efficient retransmission behaviors, and Congestion-avoid Data Distributor (CDD) that serves to enable Partial-Reliable retransmission to mitigate congestion condition. …”
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Administration of Recombinant Heat Shock Protein 70 Delays Peripheral Muscle Denervation in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis by David J. Gifondorwa, Ramon Jimenz-Moreno, Crystal D. Hayes, Hesam Rouhani, Mac B. Robinson, Jane L. Strupe, James Caress, Carol Milligan

“…The exogenous rhHsp70 was localized to the muscle and not to spinal cord or brain suggesting it modulates peripheral pathophysiology. In the current study, we focused on earlier administration of Hsp70 and its effect on initial muscle denervation. …”
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A Polynomial-Time Algorithm for Detection of Uncovered Transitions in a Petri Net-Based Concurrent System by Marcin Wojnakowski, Maxim Maliński, Remigiusz Wiśniewski, Andrzej Obuchowicz, Zhiwu Li, Dawid Konarczak

“…The effectiveness and efficiency of the proposed technique is verified experimentally with a set of 386 test modules (benchmarks) and compared against two well-known established methods: the classical method proposed by Martínez–Silva (as a reference algorithm) and PIPE (Platform Independent Petri Net Editor) tool. …”
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Temporary Redundant Transmission Mechanism for SCTP Multihomed Hosts by D. Mohana Geetha, S. K. Muthusundar, M. Subramaniam, Kathirvel Ayyaswamy

“…MSACMT-RTv2 algorithm is simulated using the Delaware University ns-2 SCTP/CMT module (ns-2; V2.29). We present and discuss MSACMT-RTv2 performance in asymmetric path delay and with finite receiver buffer (rbuf) size. …”
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Two Small Peptides from <i>Buthus martensii</i> Hydrolysates Exhibit Antitumor Activity Through Inhibition of TNF-α-Mediated Signal Transduction Pathways by Mengshuang Zhu, Shanshan Zhang, Jiyang Tang, Hairong Hou, Lizhen Wang, Houwen Lin, Xuanming Zhang, Meng Jin

“…The peptides AK and GK competitively bound to the receptor to modulate the TNF/TNFR-signaling cascade and alter the tumor microenvironment. …”
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CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3 by Vineeta Kaushik, Luca Gessa, Nelam Kumar, Matyáš Pinkas, Mariusz Czarnocki-Cieciura, Krzysztof Palczewski, Jiří Nováček, Humberto Fernandes

“…Comprised of four retinoid-binding modules, RBP3 also binds fatty acids, potentially aiding retinal function by facilitating the loading and unloading of different retinoids at specific cell types thereby directing the cycle. …”
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GnIH secreted by green light exposure, regulates bone mass through the activation of Gpr147 by Yu You, Konglin Huo, Liang He, Tongyue Wang, Lei Zhao, Rong Li, Xiaoqing Cheng, Xuebin Ma, Zhiying Yue, Stefan Siwko, Ning Wang, Lujian Liao, Mingyao Liu, Jian Luo

“…Therefore, our study elucidates that GnIH plays an important role in maintaining bone homeostasis via modulating osteoclast differentiation and demonstrates the potential of GnIH therapy or green light therapy in preventing osteoporosis.…”
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ANFIS-optimized control for resilient and efficient supply chain performance in smart manufacturing by Mona A. AbouElaz, Bilal Naji Alhasnawi, Bishoy E. Sedhom, Vladimír Bureš

“…As a result, they develop Cyber-Physical Production Systems (CPPS) by integrating CPS modules into their manufacturing processes. This integration is founded on the belief that value-added services result from technological advancements. …”
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Development of Gas Safety Management System for Smart-Home Services by Gyoutae Park, Geunjun Lyu, Youngdo Jo, Jaheon Gu, Jongbu Eun, Hiesik Kim

“…We propose a system for improving gas safety management through the use of wireless communication modules and intelligent gas safety appliances. Our system configuration consists of an automatic extinguishing system, detectors, a wall-pad, and a microcomputer controlled micom gas meter to monitor gas flow and pressure as well as the occurrence of earthquakes. …”
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Notch/CXCR4 Partnership in Acute Lymphoblastic Leukemia Progression by Georgia Tsaouli, Elisabetta Ferretti, Diana Bellavia, Alessandra Vacca, Maria Pia Felli

“…By analyzing their relevant roles in the pathogenesis of the two ALL forms, new molecular mechanisms able to modulate cancer cell invasion may be visualized. Notably, the partnership between Notch and CXCR4 may have considerable implications in understanding the complexity of T- and B-ALL. …”
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Gap Junctions Are Involved in the Rescue of CFTR-Dependent Chloride Efflux by Amniotic Mesenchymal Stem Cells in Coculture with Cystic Fibrosis CFBE41o- Cells by Annalucia Carbone, Roberto Zefferino, Elisa Beccia, Valeria Casavola, Stefano Castellani, Sante Di Gioia, Valentina Giannone, Manuela Seia, Antonella Angiolillo, Carla Colombo, Maria Favia, Massimo Conese

“…Cx43 downregulation determined also a decrease in transepithelial resistance and an increase in paracellular permeability as compared with control cocultures, implying that GJIC may regulate CFTR expression and function that in turn modulate airway epithelium tightness. These results indicate that GJIC is involved in the correction of CFTR chloride channel activity upon the acquisition of an epithelial phenotype by hAMSCs in coculture with CF cells.…”
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CircXYLT1 suppresses oxidative stress and promotes vascular remodeling in aging mice carotid artery injury model of atherosclerosis via PTBP1 by Gang Li, Donghui Li, Yajing Li, Bingqi Liu

“…Mechanistically, CircXYLT1 interacted with PTBP1, reducing its nuclear localization and modulating downstream chemokine signaling pathways. …”
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The NIN transcription factor coordinates CEP and CLE signaling peptides that regulate nodulation antagonistically by Carole Laffont, Ariel Ivanovici, Pierre Gautrat, Mathias Brault, Michael Anthony Djordjevic, Florian Frugier

“…Overall, these results demonstrate that a cytokinin-MtCRE1-MtNIN regulatory module coordinates the expression of two antagonistic, symbiosis-related, peptide hormones from different families to fine-tune nodule number.…”
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The role of natural products targeting macrophage polarization in sepsis-induced lung injury by Yake Li, Sinan Ai, Yuan Li, Wangyu Ye, Rui Li, Xiaolong Xu, Qingquan Liu

“…An increasing number of studies suggest that natural products (NPs) can alleviate SALI by modulating macrophage polarization through various targets and pathways. …”
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Effect of Codoping Cl Anion and 5-AVA Cation on Performance of Large-Area Perovskite Solar Cells with Double-Mesoporous Layers by Yaxian Pei, Xiaoping Zou, Yingxiang Guan, Gongqing Teng

“…Here we investigated the optoelectronic properties of the prototypical CH3NH3PbI3 (MAPbI3) further modulated by introducing other extrinsic ions (specifically codoped Cl− and 5-AVA+). …”
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Occupational Therapy Students’ Perceptions of the Role of Robots in the Care for Older People Living in the Community by Sławomir Tobis, Mirosława Cylkowska-Nowak, Katarzyna Wieczorowska-Tobis, Mariola Pawlaczyk, Aleksandra Suwalska

“…Limitations and Recommendations for Further Research. A module concerning technology use, including robotics, should constitute an important part of the curricula of both academic and continuous education of OTS.…”
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Increased Nuclear Transporter KPNA2 Contributes to Tumor Immune Evasion by Enhancing PD-L1 Expression in PDAC by Kai-Xia Zhou, Shan Huang, Li-Peng Hu, Xue-Li Zhang, Wei-Ting Qin, Yan-Li Zhang, Lin-Li Yao, Yanqiu Yu, Yao-Qi Zhou, Lei Zhu, Jianguang Ji, Zhi-Gang Zhang

“…Furthermore, we uncovered that KPNA2 modulated the expression of PD-L1 by mediating nuclear translocation of STAT3. …”
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Disruption of Energy Metabolism and Reactive Oxygen Species Homeostasis in Honglian Type-Cytoplasmic Male Sterility (HL-CMS) Rice Pollen by Wang Mingyue, Zhao Weibo, Feng Xiaoya, Chen Yi, Li Junhao, Fu Jinmei, Yan Yingchun, Chu Zhaohui, Huang Wenchao

“…Therefore, we propose a model in which rice fertility is modulated by the levels of pollen carbohydrates and flavonoid metabolites, with impaired mitochondrial energy production and reduced flavonoid biosynthesis as the main causes of ROS accumulation and pollen abortion in rice.…”
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