A split intein and split luciferase-coupled system for detecting protein-protein interactions by Zhong Yao, Jiyoon Kim, Betty Geng, Jinkun Chen, Victoria Wong, Anna Lyakisheva, Jamie Snider, Marina Rudan Dimlić, Sanda Raić, Igor Stagljar

“…Moreover, we designed the new SIMPL-tNLuc (‘SIMPL2’) platform with an inherent modularity allowing for flexible measurement of molecular modulators of target PPIs, including inhibitors, molecular glues and PROTACs. …”
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Molecular simulations reveal intricate coupling between agonist-bound β-adrenergic receptors and G protein by Yanxiao Han, John R.D. Dawson, Kevin R. DeMarco, Kyle C. Rouen, Khoa Ngo, Slava Bekker, Vladimir Yarov-Yarovoy, Colleen E. Clancy, Yang K. Xiang, Surl-Hee Ahn, Igor Vorobyov

“…Summary: G protein-coupled receptors (GPCRs) and G proteins transmit signals from hormones and neurotransmitters across cell membranes, initiating downstream signaling and modulating cellular behavior. Using advanced computer modeling and simulation, we identified atomistic-level structural, dynamic, and energetic mechanisms of norepinephrine (NE) and stimulatory G protein (Gs) interactions with β-adrenergic receptors (βARs), crucial GPCRs for heart function regulation and major drug targets. …”
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Karyotype Patterns of Hypsolebias antenori (Cyprinodontiformes: Rivulidae): An Endangered Killifish of the Semiarid Region of Brazil by Wallace Silva do Nascimento, Juliana Galvão Bezerra, Paulo Augusto Lima-Filho, Maria Emília Yamamoto, Sathyabama Chellappa, Wagner Franco Molina

“…Unlike the other species of this family which show an evolution modulated by events of centric fusions, H. antenori shows the maintenance of a basal diploid number and the large number of bibrachial elements indicates karyotypic diversification derived by pericentric inversions. …”
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Characteristics of an Internal Dielectric Barrier Discharge Plasma-induced Blowing Device by Y. Zhang, B. Dong, D. Yang, X. Yan, Y. Li

“…Deflection of the channel inlet or outlet introduces more possibilities for the installation of IDBD plasma actuators, albeit with a loss of about 15% of the kinetic energy of the blowing. With a modulated wave setup, the plasma actuator allows for unsteady blowing and generates frequency-controllable vortices, providing new possibilities for active control of frequency-specific wake streams. …”
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Research and Software Design of an Φ-OTDR-Based Optical Fiber Vibration Recognition Algorithm by Bernard Marie Tabi Fouda, Dezhi Han, Bowen An, Xiangzhi Chen

“…This paper proposes the time-frequency characteristic (TFC) method for the recognition of the fiber vibration signal and designs and implements the corresponding software function module. The combination of time-domain features and time-frequency-domain features is called TFC; and it is based on the Hilbert transform and on the empirical mode decomposition (EMD) of time-frequency entropy and center-of-gravity frequency that is described. …”
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A Small Ku-Band Polarization Tracking Active Phased Array for Mobile Satellite Communications by Wei Shi, Zuping Qian, Jun Zhou, Xinbo Qu, Yang Xiang, Liu Hong

“…The compact polarization tracking modules based on the low-temperature cofired ceramic (LTCC) system-in-package (SiP) technology are proposed. …”
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Microbial Translocation in Chronic Liver Diseases by Marilia Rita Pinzone, Benedetto Maurizio Celesia, Michele Di Rosa, Bruno Cacopardo, Giuseppe Nunnari

“…Therapeutic strategies aiming at modulating the gut microflora and reducing MT have focused on antibiotic-based options, such as selective intestinal decontamination, and nonantibiotic-based options, such as prokinetics and probiotics. …”
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Depression in Parkinson’s Disease: The Contribution from Animal Studies by Jéssica Lopes Fontoura, Camila Baptista, Flávia de Brito Pedroso, José Augusto Pochapski, Edmar Miyoshi, Marcelo Machado Ferro

“…The dopaminergic role could be more significant, since it can modulate the release of the others, and its depletion is progressive, due to the degenerative feature of PD. …”
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Design of antiferroelectric polarization configuration for ultrahigh capacitive energy storage via increasing entropy by Yongxiao Zhou, Tianfu Zhang, Liang Chen, Huifen Yu, Ruiyu Wang, Hao Zhang, Jie Wu, Shiqing Deng, He Qi, Chang Zhou, Jun Chen

“…Here, entropy increase effect is utilized to simultaneously break the long-range antiferroelectric order and locally adjust the fourfold commensurate modulated polarization configuration, leading to a breakthrough in the trade-off between recoverable energy storge density (14.8 J cm−3) and efficiency (90.2%) in medium-entropy antiferroelectrics. …”
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Crosstalk between Tumor-Infiltrating Immune Cells and Cancer-Associated Fibroblasts in Tumor Growth and Immunosuppression of Breast Cancer by Jarupa Soongsathitanon, Pranisa Jamjuntra, Nuttavut Sumransub, Supaporn Yangngam, Marjorie De la Fuente, Glauben Landskron, Peti Thuwajit, Marcela A. Hermoso, Chanitra Thuwajit

“…Cancer-associated fibroblasts (CAFs) are the most abundant stromal component and can modulate tumor progression according to their secretomes. …”
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Geometry-symmetry-free and material-symmetry-guaranteed polariton-induced transparency by Xingyu Tang, Huaping Wang, Zhenyang Cui, Sihao Xia, Zhiwei He, Song Han, Hongsheng Chen, Yingjie Wu

“…These findings highlight the potential of polariton modes beyond PPs in PIT systems, with applications in sensors, modulators, and slow light systems.…”
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Temperature Response of the HTR-10 during the Power Ascension Test by Fubing Chen, Yujie Dong, Zuoyi Zhang

“…The 10 MW High Temperature Gas-Cooled Reactor-Test Module (HTR-10) is the first High Temperature Gas-Cooled Reactor in China. …”
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Butyrate-engineered yeast activates Nppa and Sgcg genes and reduces radiation-induced heart damage via the gut-heart axis by Jiahao Wu, Kaihua Ji, Guangbo Kang, Manman Zhang, Jigang Wang, Lina Wang, Mengxue Gao, Xiaoxiao Jia, Xinran Lu, Yan Wang, Xinran Gao, Yufei Guo, Zhixin Zhu, Qinghua Wang, Zhenyu Zhao, Qiang Liu, He Huang

“…Mechanistically, engineered yeast enhanced taurine and nicotinamide metabolism by increasing the relative abundance of Akkermansia and Lachnospiraceae_NK4A136; then, yeast modulated cardiac function by activating the Sgcg and Nppa genes to attenuate cardiac damage induced by abdominal irradiation. …”
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A novel buffering fault‐tolerance approach for network on chip (NoC) by Nima Jafarzadeh, Ahmad Jalili, Jafar A. Alzubi, Khosro Rezaee, Yang Liu, Mehdi Gheisari, Bahram Sadeghi Bigham, Amir Javadpour

“…NoC is a network‐based communication subsystem on an integrated circuit, most typically between modules in a system on a chip (SoC). Designing a reliable NoC against failures that can prevent failure using some measures or preventing error or system failure while failure happens and proper performance became a significant concern. …”
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MFIEN: multi-scale feature interactive enhancement network for seismic data denoising in desert areas by Tie Zhong, Yuxin Ye

“…Furthermore, a fusion feature enhancement module (FFEM), incorporating dilated convolutions and convolutions with different kernel sizes, is proposed. …”
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Igf2/H19 Imprinting Control Region (ICR): An Insulator or a Position-Dependent Silencer? by Subhasis Banerjee, Alan Smallwood, Scott Lamond, Stuart Campbell, Geeta Nargund

“…The imprinting control region (ICR) located far upstream of the H19 gene, in conjunction with enhancers, modulates the transcription of Igf2 and H19 genes in an allele-specific manner. …”
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Highly Parallel Regular Expression Matching Using a Real Processing-in-Memory System by Jeonghyeon Joo, Hyojune Kim, Hyuck Han, Eul Gyu Im, Sooyong Kang

“…Processing-in-Memory (PIM) is an emerging computing paradigm exploiting a cutting-edge memory device (PIM device) that integrates hundreds to thousands of processing units with the memory modules. A data-intensive application running in a host system can offload a portion of its tasks to the processing units in the PIM device, not only to exploit their processing capabilities but also to mitigate the contention in host memory accesses. …”
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Field measurement of atmospheric CO₂ column abundance based on portable laser heterodyne radiometer by Yong Wang, Yong Wang, Maolei Zhang, Maolei Zhang, Jiapeng Wang, Jiapeng Wang, Gang Wang, Gang Wang, Ruyue Cui, Ruyue Cui, Lei Dong, Lei Dong, Hongpeng Wu, Hongpeng Wu

“…This study presents a portable near-infrared laser heterodyne radiometer specifically designed for measuring the column abundance of atmospheric carbon dioxide (CO₂) in the Taiyuan area. The instrument modulates the solar radiation using a fiber optic switch and amplifies the solar radiation through a semiconductor optical amplifier. …”
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Orthogonal Capsule Network with Meta-Reinforcement Learning for Small Sample Hyperspectral Image Classification by Prince Yaw Owusu Amoako, Guo Cao, Boshan Shi, Di Yang, Benedict Boakye Acka

“…The OCN-MRL framework employs Meta-RL for feature selection and CapsNet for classification with a small data sample. The Meta-RL module through clustering, augmentation, and multiview techniques enables the model to adapt to new HSIC tasks with limited samples. …”
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MUFFNet: lightweight dynamic underwater image enhancement network based on multi-scale frequency by Dechuan Kong, Dechuan Kong, Yandi Zhang, Xiaohu Zhao, Yanqiang Wang, Lei Cai

“…A Multi-Scale Enhancement Prior algorithm enhances high-frequency and low-frequency features while the Information Flow Interaction module mitigates information stratification and blockage. …”
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