Paediatric Inflammatory Bowel Disease: A Mechanistic Approach to Investigate Exclusive Enteral Nutrition Treatment by Lily Nahidi, Andrew S. Day, Daniel A. Lemberg, Steven T. Leach

“…Although several pharmacological approaches are used to modulate the inflammatory response in IBD, few lead to histological healing and most have side effects. …”
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Anti-Scar Effects of Micropatterned Hydrogel after Glaucoma Drainage Device Implantation by Yiling Han, Qiangwang Geng, Aimeng Dong, Menglu Jiang, Jingyi Ma, Wulian Song, Pan Fan, Yuanyuan Li, Jiawen Gao, Fenghua Zhang, Jinsong Leng, Huiping Yuan

“…Although it is known that in implanted medical devices, microscale modification of the implant surface can modulate cell behavior and reduce the incidence of fibrosis, in the field of ophthalmic implants, especially the modification and effects of hydrogel micropatterns have rarely been reported. …”
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Computer-aided simulation of unmanned aerial vehicle composite structure dynamics by Artur Kierzkowski, Tomasz Kisiel, Maciej Milewski, Ádám Török, Michał Stosiak, Jakub Wróbel

“…ANSYS software and the ACP module were employed to develop a numerical model of a wet Epoxy Carbon UD (230 GPa) composite commonly used in Unmanned Aerial Vehicle (UAV) components. …”
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DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism by Xinrong Wu, Yifan Li, Weiwei Wang, Jiale Xu, Bei Zhao, Wenqi Sun, Dan Ge, Longying Xiong, Xiaotan Dou, Xiaoping Zou, Lei Wang, Min Chen

“…DNA damage-regulated autophagy modulator 1 (DRAM1) encodes a hexameric transmembrane protein that is predominantly located in lysosomes and induces autophagy; however, its mechanism of action in gastric cancer remains unclear. …”
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Artificial simulated saliva, gastric and intestinal digestion and fermentation in vitro by human gut microbiota of intrapolysaccharide from Paecilomyces cicadae TJJ1213 by Juanjuan Tian, Xiaomeng Wang, Xueliang Zhang, Xiaohong Chen, Mingsheng Dong, Xin Rui, Qiuqin Zhang, Mei Jiang, Wei Li

“…Alpha-diversity, beta-diversity and taxonomic composition differences analysis revealed that IPS1 and IPS2 promoted the proliferation of beneficial bacteria and modulated the overall structure of gut microbiota. …”
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Heparin Interaction with the Primed Polymorphonuclear Leukocyte CD11b Induces Apoptosis and Prevents Cell Activation by Meital Cohen-Mazor, Rafi Mazor, Batya Kristal, Erik B. Kistler, Inbal Ziv, Judith Chezar, Shifra Sela

“…To test our hypothesis, we designed both in vitro and ex vivo studies to elucidate the mechanism by which heparin modulates PMNL functions and therefore the inflammatory response. …”
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Metal ion-crosslinking multifunctional hydrogel microspheres with inflammatory immune regulation for cartilage regeneration by Zhuoming Xu, Zhuoming Xu, Jun Ma, Hanyin Hu, Hanyin Hu, Jintao Liu, Jintao Liu, Haiyang Yang, Haiyang Yang, Jiayi Chen, Hongwei Xu, Xinyu Wang, Huanhuan Luo, Gang Chen

“…Due to the complex pathogenesis of OA, multifaceted therapies that modulate inflammatory and immune microenvironmental disturbances while promoting cartilage regeneration are key to control the progression of OA.MethodsHerein, a multifunctional nanoparticle (DIC/Mg-PDA NPs) was constructed successfully by the metal chelation effect between Mg2+ and catecholamine bond from dopamine, followed by the amidation with diclofenac (DIC), which was then prepared into an injectable hydrogel microsphere (DIC/Mg-PDA@HM) with immune-regulating and cartilage-repairing abilities through microfluidic technology for the treatment of osteoarthritis.Results and discussionThe sustained release of Mg2+ from the composite hydrogel microspheres achieved inflammatory immune regulation by converting macrophages from M1 to M2 and promoted cartilage regeneration through the differentiation of BMSCs. …”
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Using technology to increase reach and optimize consent experience for a large-scale research program by Emma Coen, Daniel P. Judge, Samantha Norman, John T. Clark, Andrew Cates, Randolph Thornhill, Kelly Hunt, Lori McMahon, Leslie Lenert, Caitlin G. Allen

“…Future modifications include incorporating video modules and launching a Spanish version of the consent experience. …”
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On-chip power efficient MHz to GHz tunable Brillouin microwave photonic filters by Reena Parihar, Choon Kong Lai, Ziqian Zhang, Duk-Yong Choi, Stephen J. Madden, Benjamin J. Eggleton, Amol Choudhary, Moritz Merklein

“…However, broadband filters utilizing Brillouin scattering typically necessitate multiple pump sources or linear frequency modulated waveforms, which necessitate the use of overall high pump powers to achieve broadband and multi-band filter configurations. …”
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Automated Computer Vision System for Urine Color Detection by Ban Shamil Abdulwahed, Ali Al-Naji, Izzat Al-Rayahi, Ammar Yahya, Asanka G. Perera

“…In addition, the proposed system can send the results to the mobile phone of the patient or care provider by using an Arduino microcontroller and GSM module. Moreover, sending a voice message about the color of urine is related to pathological conditions. …”
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Weakening Relationship between East Asian Summer Monsoon and Asian-Pacific Oscillation after 1990s by Wei Hua, Zouxin Lin, Xin Wang, Guangzhou Fan

“…The Asian-Pacific Oscillation (APO) can modulate the EASM because it not only represents the upper-tropospheric zonal land-sea thermal contrast over Asia and the Pacific region, but it also affects the sea surface temperature (SST) over the North Pacific, which can tune the land-sea thermal contrast for the EASM. …”
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Transient receptor potential channels in dental inflammation and pain perception: A comprehensive review by Varunya Chantadul, Nattapon Rotpenpian, Tawepong Arayapisit, Aree Wanasuntronwong

“…Pharmacological interventions and emerging strategies aimed at modulating TRP channel activity are critically evaluated. …”
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An Improved Runway Operation Capacity Model for V-Open Multirunway Airports in China by Zhiyuan Shen, Xinyu Xu, Yong He, YongGang Yan, Lin Zhou, Yingying Hu

“…To address these problems, an improved runway operation capacity model for a V-open multirunway airport is proposed to reduce the separation standard based on the equivalent lateral separation operation (ELSO) standard. A collision risk module is first proposed to assess the feasibility and safety of the proposed policy. …”
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The Microbiota Determines Susceptibility to Experimental Autoimmune Uveoretinitis by Jarmila Heissigerova, Petra Seidler Stangova, Aneta Klimova, Petra Svozilkova, Tomas Hrncir, Renata Stepankova, Miloslav Kverka, Helena Tlaskalova-Hogenova, John V. Forrester

“…The microbiota is a crucial modulator of the immune system. Here, we evaluated how its absence or reduction modifies the inflammatory response in the murine model of experimental autoimmune uveoretinitis (EAU). …”
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Freestanding VO2 membranes on epidermal nanomesh for ultra-sensitive correlated breathable sensors by Dongha Kim, Dongju Lee, Jiseok Park, Jihoon Bae, Aiping Chen, Judith L. MacManus-Driscoll, Sungwon Lee, Shinbuhm Lee

“…The resistance of the VO2 membranes is reversibly tuned by human’s tiny mechanical stimuli and breath stimuli. The stimuli modulate the Peierls dimerization of one-dimensional V−V chains in the VO2 lattice which concomitantly controls the electron correlation and hence resistivity. …”
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Chemical ethics practices in HEBUST of China by Liu Xinwei, Wu Tong, Sun Yujuan, Gu Limin, Wen Jingjing, Liu Shaohui, Yang Kun, Sun Fengxia

“…Hebei University of Science and Technology (HEBUST) actively carries out chemical ethics education practices and incorporates chemical ethics modules into the curriculum, aiming to improve students’ morality, responsibility, knowledge and skills. …”
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Real-Time Optimization of RISC-V Processors Based on Branch Prediction and Division Data Dependency by Zhiwei Jin, Hesong Di, Tingpeng Hu, Peng Wang

“…The processor is optimized for real-time performance using a “simplified local history branch predictor” and a “division data dependency module”. Experimental results show that the processor’s branch prediction accuracy and division calculation speed have both improved. …”
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Thermal design of a thermoelectric refrigerator operating near room temperature using artificial neural network by Hichem Ykrelef, Younes Chiba, Mounir Zirari, Ahmed Benyekhlef, Abdelali Boukaoud, Djamel Sebbar, Abdelkrim Kherkhar, Hayati Mamur

“…Abstract The current study aimed to design and test a prototype of a thermoelectric cooler (TEC) using thermoelectric modules (TEM) operating near room temperature. The thermoelectric cooler utilized in this investigation has a maximum cooling power of 46 W and dimensions of 40 mm × 40 mm × 3.6 mm. …”
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Cofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions. by Miguel Ángel Pérez-Castro, Hasier Eraña, Enric Vidal, Jorge M Charco, Nuria L Lorenzo, Nuno Gonçalves-Anjo, Josu Galarza-Ahumada, Carlos M Díaz-Domínguez, Patricia Piñeiro, Ezequiel González-Miranda, Samanta Giler, Glenn Telling, Manuel A Sánchez-Martín, Joseba Garrido, Mariví Geijo, Jesús R Requena, Joaquín Castilla

“…Our study aimed to explore the influence of a polyanionic cofactor in modulating strain selection and infectivity in de novo-generated synthetic prions. …”
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SqueezeMaskNet: Real-Time Mask-Wearing Recognition for Edge Devices by Gibran Benitez-Garcia, Lidia Prudente-Tixteco, Jesus Olivares-Mercado, Hiroki Takahashi

“…We propose using Fire modules for efficiency, along with attention mechanisms like efficient channel attention (ECA) and squeeze-and-excitation (SE) blocks for improved feature refinement. …”
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