-
4721
Chirality Evolution of Supramolecular Helices by Electron Transfer Assisted Secondary Nucleation
Published 2025-02-01“…This study may provide a useful approach to constructing and modulating diverse chiral structures by manipulating the secondary nucleation process.…”
Get full text
Article -
4722
Psychological Factors Associated with Phantom Limb Pain: A Review of Recent Findings
Published 2018-01-01“…The reported findings indicate that emotional factors modulate PLP but might be less important compared to other types of chronic pain. …”
Get full text
Article -
4723
Aptamers: A Feasible Technology in Cancer Immunotherapy
Published 2016-01-01“…A variety of aptamers described to date have been shown to be reliable in modulating immune responses against cancer by either blocking or activating immune receptors. …”
Get full text
Article -
4724
Investigation Performance and Mechanisms of Inverted Polymer Solar Cells by Pentacene Doped P3HT : PCBM
Published 2014-01-01“…It was demonstrated that the pentacene doping modulated the electron mobility and the hole mobility in the resulting absorption layer. …”
Get full text
Article -
4725
Injectable hyaluronic acid-based hydrogel niches to create localized and time-controlled therapy delivery
Published 2025-04-01“…Our results indicate that heparin incorporation can delay cytokine release, while the release of nanocarriers can be regulated by adjusting the crosslinking degree. This design modulates pore size and degradation time, while preserving the injectability of the niche. …”
Get full text
Article -
4726
Endogenous electric field-driven neuro-immuno-regulatory scaffold for effective diabetic wound healing
Published 2025-05-01“…Exogenous electrical stimulation (ES), by modulating the electric field distribution in wounds, has shown significant potential in treating inflammatory wounds. …”
Get full text
Article -
4727
Research Progress of ROS-Mitochondrial Pathway on Cardiovascular Protection of Tea Polyphenols
Published 2025-02-01“…From the perspective of ROS-mitochondrial pathway, the article elucidates how tea polyphenols behaved the beneficial effects against cardiovascular diseases by modulating the expression of mitochondrial fusion and fission proteins, reducing the opening of mitochondrial membrane permeability transition pore, maintaining cellular calcium homeostasis, mitigating mitochondrial DNA damage and regulating mitochondrial apoptosis signaling pathways. …”
Get full text
Article -
4728
IFI44L as a Forward Regulator Enhancing Host Antituberculosis Responses
Published 2021-01-01“…This study showed that IFI44L acts as an antimicrobial target and positive modulator in human macrophages. Knockdown of IFI44L led to increased Mycobacterium tuberculosis intracellular survival. …”
Get full text
Article -
4729
Vitamin D in Early Childhood and the Effect on Immunity to Mycobacterium tuberculosis
Published 2012-01-01“…As early as birth a child is often deficient in vitamin D, which may not only affect their bone metabolism but also modulate their immune function, contributing to the increased susceptibility to many infections seen early in life. …”
Get full text
Article -
4730
Semantic‐aware visual consistency network for fused image harmonisation
Published 2023-06-01“…To better preserve the input semantic information, the authors design a simple and effective semantic‐aware adaptive denormalisation (SADE) module. Experimental results demonstrate that the authors’ proposed method achieves competitive performance on the iHarmony4 dataset and benefits from the harmonisation of fused images with incompatible appearance gaps.…”
Get full text
Article -
4731
Contribution of Neuronal and Glial Two-Pore-Domain Potassium Channels in Health and Neurological Disorders
Published 2021-01-01“…A range of natural and chemical effectors, including temperature, pressure, pH, phospholipids, and intracellular signaling molecules, substantially modulate the activity of K2P channels. In this review, we summarize the contribution of K2P channels to neuronal excitability and to potassium homeostasis in glia. …”
Get full text
Article -
4732
Effective in vivo binding energy landscape illustrates kinetic stability of RBPJ-DNA binding
Published 2025-02-01“…How TF-DNA binding kinetics and cofactor interactions modulate gene regulation is mostly unknown. We determine the binding kinetics, transcriptional activity, and genome-wide chromatin occupation of RBPJ and mutant variants by live-cell single-molecule tracking, reporter assays, and ChIP-Seq. …”
Get full text
Article -
4733
Drug-target binding affinity prediction based on power graph and word2vec
Published 2025-01-01“…Conclusions In this model, the drug molecular features in the power graph module are extracted by a graph neural network, and then the protein features are obtained by the Word2vec method. …”
Get full text
Article -
4734
Strategies Affording Prevascularized Cell-Based Constructs for Myocardial Tissue Engineering
Published 2014-01-01“…In addition to these basic approaches, more sophisticated strategies have been followed employing mixed-cell sheets, microvascular modules, and inosculation from vascular explants. …”
Get full text
Article -
4735
Secretory Products of Trichinella spiralis Muscle Larvae and Immunomodulation: Implication for Autoimmune Diseases, Allergies, and Malignancies
Published 2015-01-01“…Those products can successfully modulate parasite-specific immune responses as well as responses to unrelated antigens (either self or nonself in origin), providing an anti-inflammatory milieu and maintaining homeostasis. …”
Get full text
Article -
4736
Lactic Acid Bacteria Strains Exert Immunostimulatory Effect on H. pylori-Induced Dendritic Cells
Published 2015-01-01“…The aim of this study was to find out if selected lactic acid bacteria (LAB) strains (antagonistic or nonantagonistic against H. pylori in vitro) would differ in their abilities to modulate the DCs maturation profiles reflected by their phenotype and cytokine expression patterns. …”
Get full text
Article -
4737
High Quality GaAs Epilayers Grown on Si Substrate Using 100 nm Ge Buffer Layer
Published 2016-01-01“…The thin Ge buffer layers were modulated by hydrogen flow rate from 60 to 90 sccm to improve crystal quality by electron cyclotron resonance chemical vapor deposition (ECR-CVD) at low growth temperature (180°C). …”
Get full text
Article -
4738
NLRP3 Deficiency Attenuates Renal Fibrosis and Ameliorates Mitochondrial Dysfunction in a Mouse Unilateral Ureteral Obstruction Model of Chronic Kidney Disease
Published 2017-01-01“…The present study was performed to identify the function of NLRP3 in modulating renal injury and fibrosis and the potential involvement of mitochondrial dysfunction in the murine unilateral ureteral obstruction (UUO) model of CKD. …”
Get full text
Article -
4739
Mesenchymal Stem Cell-Based Immunomodulation: Properties and Clinical Application
Published 2018-01-01“…Numerous bioactive molecules secreted by MSCs, particularly cytokines, growth factors, and chemokines, exert autocrine/paracrine effects that modulate the physiological processes of MSCs. These invaluable virtues of MSCs provide new insight into potential treatments for tissue damage and inflammation. …”
Get full text
Article -
4740
Development, implementation and evaluation of consultation case-based learning course to improve the interdisciplinary clinical reasoning ability-a pilot study from nephrology
Published 2025-01-01“…Results The ten-week interdisciplinary course were successfully implemented according to the planned training schedule. 26 residents from different majors were included, and 24 of the residents completed the modules and evaluation. Over 90% participants were satisfied with our course, and over 79.2% participants achieved improved interdisciplinary skills. …”
Get full text
Article