Bacterial metabolism in the host and its association with virulence by Amrita Bhagwat, Tiyasa Haldar, Poonam Kanojiya, Sunil D. Saroj

“…The perspective presented herein will facilitate us with a broader view of molecular mechanisms that modulates the expression of virulence factors in bacterial pathogens. …”
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Pharmacological Correction of Stress-Induced Gastric Ulceration by Novel Small-Molecule Agents with Antioxidant Profile by Konstantin V. Kudryavtsev, Anna O. Markevich, Oleksandr V. Virchenko, Tetyana M. Falalyeyeva, Tetyana V. Beregova, Lyudmyla I. Ostapchenko, Dmitry V. Zabolotnev, Nikolay S. Zefirov

“…Discovered small-molecule antiulcer agents modulate activities of gastric mucosa tissue superoxide dismutase, catalase, and xanthine oxidase in concerted directions. …”
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Importins and Exportins Regulating Allergic Immune Responses by Ankita Aggarwal, Devendra K. Agrawal

“…In addition, several immune modulators, including corticosteroids and vitamin D, elicit their cellular responses by regulating the expression and activity of importin molecules. …”
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Cytokine Immunopathogenesis of Enterovirus 71 Brain Stem Encephalitis by Shih-Min Wang, Huan-Yao Lei, Ching-Chuan Liu

“…Administration of intravenous immunoglobulin and milrinone, a phosphodiesterase inhibitor, has been shown to modulate inflammation, to reduce sympathetic overactivity, and to improve survival in patients with EV71 autonomic nervous system dysregulation and pulmonary edema.…”
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Modification of peroxidase activity and proteome in maize exposed to cadmium in the presence of galactoglucomannan oligosaccharides by Diana Hačkuličová, Eva Labancová, Zuzana Vivodová, Maksym Danchenko, Kristína Holeková, Marko Bajus, Danica Kučerová, Peter Baráth, Karin Kollárová

“…The GGMOs in the presence of Cd did not significantly influence content of peroxidases but modulated their activity, which implies posttranslational regulation. …”
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RESEARCH CONCERNING THE POSITIONAL ANALYSIS OF A FOURTH CLASS MECHANISM by Georgeta Toma

“…Solving the system of equations was done numerically, using the fsolve module included in the Maple program. The results obtained from solving the system of equations allowed the development of a functioning simulator of the analyzed mechanism. …”
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Competing Endogenous RNA: The Key to Posttranscriptional Regulation by Rituparno Sen, Suman Ghosal, Shaoli Das, Subrata Balti, Jayprokas Chakrabarti

“…Competing endogenous RNA, ceRNA, vie with messenger RNAs (mRNAs) for microRNAs (miRNAs) with shared miRNAs responses elements (MREs) and act as modulator of miRNA by influencing the available level of miRNA. …”
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GutBugDB: a web resource to predict the human gut microbiome-mediated biotransformation of biotic and xenobiotic molecules by Usha Longwani, Ashok K. Sharma, Aditya S. Malwe, Shubham K. Jaiswal, Vineet K. Sharma

“…The determination of species-specific contributions to the metabolism of biotic and xenobiotic molecules has the potential to aid in the development of new therapeutic and nutraceutical molecules that can modulate human gut microbiota. Here we present “GutBugDB,” an open-access digital repository that provides information on potential gut microbiome-mediated biotransformation of biotic and xenobiotic molecules using the predictions from the GutBug tool. …”
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Global Warming Amplifies Outdoor Extreme Moist Heat During the Indian Summer Monsoon by Anukesh Krishnankutty Ambika, Akshay Rajeev, Matthew Huber

“…While research has demonstrated the importance of summer monsoon to moist heat in India, impact of monsoon‐break and warm spells in modulating extreme moist heat regionally has not been fully investigated. …”
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Enterococcus dysbiosis as a mediator of vitamin D deficiency-associated memory impairments by Elizaveta Vinogradova, Zharkyn Jarmukhanov, Madiyar Nurgaziyev, Alibek Kossumov, Ayaulym Nurgozhina, Nurislam Mukhanbetzhanov, Shynggys Sergazy, Laura Chulenabyeva, Argul Issilbayeva, Sholpan Askarova, Aiym Kaiyrlykyzy, Saule Rakhimova, Ulan Kozhamkulov, Ulykbek Kairov, Zhanagul Khassenbekova, Dinar Tarzhanova, Ainur Akilzhanova, Joseph H. Lee, Joseph Terwilliger, Aliya Sailybayeva, Makhabbat Bekbossynova, Zhaxybay Zhumadilov, Samat Kozhakhmetov, Almagul Kushugulova

“…These results underscore the importance of understanding and modulating gut microbiome composition to optimize VitD status and cognitive function.…”
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The effect of diclofenac on proliferation and production of growth factors by endothelial cells (HMEC-1) under hypoxia and inflammatory conditions by Wiktorowska-Owczarek Anna

“…Another goal was to check whether diclofenac modulates the secretion of angiogenic factors such as VEGF and bFGF in human microvascular endothelial cells (HMEC-1) in the presence of CoCl2 or lipopolysaccharide (LPS), which could influence the endothelial cells in an autocrine manner or other cells in a paracrine manner. …”
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Differential Downregulation of E-Cadherin and Desmoglein by Epidermal Growth Factor by Miquella G. Chavez, Christian A. Buhr, Whitney K. Petrie, Angela Wandinger-Ness, Donna F. Kusewitt, Laurie G. Hudson

“…Modulation of cell : cell junctions is a key event in cutaneous wound repair. …”
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Nobiletin Protects Endothelial Cell Function via Upregulation of eNOS/ET-1 and Antioxidant Status-Related Genes under Nonstimulated and Inflammatory Conditions by Lu Li, Biyun Zhang, Ludovica De Pieri, Yue Wu, Karen Birch, Christine Boesch

“…However, there is limited evidence on the molecular mechanisms by which nobiletin modulates endothelial cell function. Our aim was to investigate the potential of nobiletin to enhance endothelial cell functionality under nonstimulated and inflammatory conditions. …”
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An approach to energy conservation in lighting systems using luminaire-based sensor for automatic dimming by Chaiyan Jettanasen, Surakit Thongsuk, Chayanut Sottiyaphai, Panapong Songsukthawan, Pathomthat Chiradeja, Praikanok Lertwanitrot, Santipont Ananwattanaporn, Atthapol Ngaopitakkul

“…A system comprising an ambient light sensor, microcontroller, power supply module, dimming controller, and lamp was developed. …”
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Trypanosoma cruzi Infection in Genetically Selected Mouse Lines: Genetic Linkage with Quantitative Trait Locus Controlling Antibody Response by Francisca Vorraro, Wafa H. K. Cabrera, Orlando G. Ribeiro, José Ricardo Jensen, Marcelo De Franco, Olga M. Ibañez, Nancy Starobinas

“…An Ab production QTL marker mapping to mouse chromosome 1 (34.8 cM) significantly cosegregated with survival after acute T. cruzi infections, indicating that this region also harbors genes whose alleles modulate resistance to acute T. cruzi infection.…”
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A Study on a Solar Simulator for Dye Sensitized Solar Cells by Kyoung-Jun Lee, Jeong-Hoon Kim, Ho-Sung Kim, Dongsul Shin, Dong-Wook Yoo, Hee-Je Kim

“…When DSSCs are commercialized in the near future, the DSSC modules must be connected to an adaptable power conditioning system in order to manage the energy produced and provide a suitable interface to the load. …”
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Divergent Effects of <i>Circoviridae</i> Capsid Proteins on Type I Interferon Signaling by Anon H. Kosaka, Chen-Yu Huang, Zih-Ying Lu, Hua-Zhen Hsing, Amonrat Choonnasard, Rissar Siringo Ringo, Kuo Pin Chuang, Akatsuki Saito

“…Our results illustrated that although the nuclear localization of capsid proteins is conserved, their effects on IFN-β signaling vary by species, revealing the diverse roles of <i>Circoviridae</i> capsid proteins in modulating immune responses.…”
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APC orchestrates microtubule dynamics by acting as a positive regulator of KIF2A and a negative regulator of CLASPs by Yong Wang, Xinping Liu, Zheng Liu, Shasha Hua, Kai Jiang

“…In addition, APC counteracts the major MT-stabilizer CLASPs at MT plus ends and promotes directional cell migration via modulating cell adhesion force. Reconstitution experiments demonstrate that APC potentiates KIF2A-induced MT catastrophes and antagonizes the stabilizing effect of CLASP2 in vitro. …”
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Palmitoylethanolamide: A Natural Body-Own Anti-Inflammatory Agent, Effective and Safe against Influenza and Common Cold by J. M. Keppel Hesselink, Tineke de Boer, Renger F. Witkamp

“…Research on PEA has been conducted for more than 50 years, and over 350 papers are referenced in PubMed describing the physiological properties of this endogenous modulator and its pharmacological and therapeutical profile. …”
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Wet pulverization combined with temperature cycling strategy for extraction of Stropharia rugosoannulata protein with attenuating hepatic steatosis on obese mice by Peng Liu, Chen Gao, Wen Li, Wanchao Chen, Zhong Zhang, Di Wu, Tingzhao Li, Shuai Sun, Yan Yang

“…Moreover, SRA repaired the cross-talk between gut microbiota and liver via modulating intestinal microecology, and restoring the integrity and function of the intestinal barrier in obese mice. …”
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