Novel Approach to Bile Duct Damage in Primary Biliary Cirrhosis: Participation of Cellular Senescence and Autophagy by Motoko Sasaki, Yasuni Nakanuma

“…Furthermore, senescent BECs may modulate the microenvironment around bile ducts by expressing various chemokines and cytokines called senescence-associated secretory phenotypes and contribute to the pathogenesis in PBC.…”
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Indoxyl Sulfate-Induced Oxidative Stress, Mitochondrial Dysfunction, and Impaired Biogenesis Are Partly Protected by Vitamin C and N-Acetylcysteine by Wen-Chin Lee, Lung-Chih Li, Jin-Bor Chen, Hsueh-Wei Chang

“…In this study, we examined whether mitochondria play a pivotal role in modulating the effects of antioxidants during IS treatment. …”
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Mesotherapy: From Historical Notes to Scientific Evidence and Future Prospects by Massimo Mammucari, Enrica Maggiori, Domenico Russo, Chiara Giorgio, Gianpaolo Ronconi, Paola E Ferrara, Flora Canzona, Luciano Antonaci, Bartolomeo Violo, Renato Vellucci, Domenico Rocco Mediati, Alberto Migliore, Umberto Massafra, Barbara Bifarini, Fabio Gori, Massimo di Carlo, Stefano Brauneis, Teresa Paolucci, Piergiovanni Rocchi, Anna Cuguttu, Raffaele Di Marzo, Alessandro Bomprezzi, Stefania Santini, Manuela Giardini, Anna Rosa Catizzone, Fiammetta Troili, Dario Dorato, Alessandra Gallo, Costanza Guglielmo, Silvia Natoli

“…The intradermal microdeposit modulates the drug’s kinetics, slowing absorption and prolonging the local mechanism of action. …”
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Gut Microbiota and Its Impact on Brain Function and Mental Health by Zofia Martyna Wójcik, Katarzyna Kamińska-Omasta, Bartosz Omasta, Olga Krupa, Paulina Dorota Pietrukaniec, Kuba Borys Romańczuk, Kinga Furtak, Szymon Przemysław Stolarczyk, Magdalena Agata Czerska, Daria Rybak

“…Recent research reveals that microbiota not only supports metabolic and immune functions but also influences central nervous system (CNS) regulation via the gut-brain axis, a two-way communication system. The gut-brain axis modulates neurotransmitter production (e.g., serotonin, GABA), immune responses, and interacts through bacterial metabolites. …”
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Color Standardization Method and System for Whole Slide Imaging Based on Spectral Sensing by Shinsuke Tani, Yasuhiro Fukunaga, Saori Shimizu, Munenori Fukunishi, Kensuke Ishii, Kosei Tamiya

“…In order to stabilize the analysis, we developed a color standardization method and system as described below: 1) Color standardization method based on RGB imaging and multi spectral sensing, which utilize less band (16 bands) than conventional method (60 bands), 2) High speed spectral sensing module. As a result, we confirmed the following effect: 1) We confirmed the performance improvement of nucleus detection by the color standardization. …”
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Microglial Dysregulation in Psychiatric Disease by Luciana Romina Frick, Kyle Williams, Christopher Pittenger

“…If microglial pathology proves to be an important causative factor in these or other neuropsychiatric diseases, modulators of microglial function may represent a novel therapeutic strategy.…”
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DC MOTOR ANGULAR POSITION CONTROL SYSTEM USING ARDUINO PLATFORM by Dragos-Ioan Matei, Alexandru Negroiu, Gabriela Bucur

“…The L298N dual H-bridge motor driver is used to modulate the PWM signal and control the travel direction. …”
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Efficient and accurate identification of maize rust disease using deep learning model by Pei Wang, Pei Wang, Jiajia Tan, Yuheng Yang, Yuheng Yang, Tong Zhang, Pengxin Wu, Xinglong Tang, Hui Li, Xiongkui He, Xinping Chen

“…To address this, a specialized Maize-Rust model integrating a SimAM module in the YOLOv8s backbone and a BiFPN for scale fusion, along with a DWConv for streamlined detection, was developed. …”
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Experimental observation of nonreciprocal magnonic frequency combs by Kaixin Zhao, Fan Yang, Chenxiao Wang, Zhijian Chen, Jiantao Song, Shuhuan Ma, Zixuan Yue, Weihao Liu, Liaoxin Sun, Jinwei Rao, Bimu Yao, Wei Lu

“…The nonreciprocal MFCs can be systematically tuned by modulating the detuning of the pump and BIC, the magnon and cavity modes, as well as the pump and perturbation tone. …”
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Differentiation therapy targeting the stalled epigenetic developmental programs in pediatric high-grade gliomas by Wang Xiang, Xiaolin Zhang, Minhai Dong, Lijun Wan, Bin Zhang, Feng Wan

“…Differentiation therapy aims to overcome this differentiation blockade by promoting glioma cell differentiation into more mature and less malignant cells. Epigenetic modulators, including inhibitors of histone deacetylase (HDAC), enhancer of zeste homolog 2 (EZH2), BRG1/BRM-associated factor (BAF) complex, have shown promise in preclinical studies of pHGGs by altering the differentiation program of glioma cells. …”
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An environment for complex behaviour detection in bio-potential experiments by Maide Bucolo, Federica Di Grazia, Luigi Fortuna, Mattia Frasca, Francesca Sapuppo

“…It includes sev-eral modules as data importing and loading, data visualization (1D, 2D, 3D),pre-processing (frequency and saturation filtering, statistical analysis), spatio-temporal processing such as power spectrum, independent component analysis(ICA) in spatial and time domain, and nonlinear analysis for the extractionof the maximum Lyapunov exponent and d ∞(d-inifnite) using optimized al-gorithms. …”
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Design and Fabrication of a PDMS-Based Manual Micro-Valve System for Microfluidic Applications by Tu N. Le, Van-Anh Nguyen, Giang L. Bach, Lam D. Tran, Ha H. Cao

“…This valve system was connected to a microfluidic device with two important modules: a multi-liquid mixing component and a micro-reactor (~5 μL of volume). …”
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Are Verbal Fluency and Nonliteral Language Comprehension Deficits Related to Depressive Symptoms in Parkinson’s Disease? by Christina Tremblay, Oury Monchi, Carol Hudon, Joël Macoir, Laura Monetta

“…This study explores whether depressive symptoms in PD modulate verbal fluency and nonliteral language comprehension. …”
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Topology-Aware Efficient Path Planning in Dynamic Environments by Haoning Zhao, Jiamin Guo, Chaoqun Wang, Xuewen Rong, Yibin Li

“…This mechanism can adaptively adjust the optimizing step size according to the change in the dynamic environment, and the sampling module uses the Gaussian Mixture Model (GMM) Optimizer to control the sampling space. …”
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The intelligent selenium-enriched tea withering control system by Shuang Ren, Sanjun Liu, Jinzhao Fan, Didi Lu

“…This control system can achieve real-time monitoring of the withering environment and automate the control of heating and ventilation dehumidification modules. By integrating IoT technology, relevant users can view the tea production process via mobile devices, enabling intelligent and remote production operations. …”
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Regulation of Nutrient Transport across the Placenta by Susanne Lager, Theresa L. Powell

“…In this paper we will focus on recent studies of regulatory mechanisms that modulate placental transport of amino acids, fatty acids, and glucose.…”
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Quarter-Wavelength Two-Section Coaxial Stepped Impedance Resonators for Harmonics Suppression in Tx Bandpass Filters by Alexandre Bonizec, Jessica Benedicto, Jean-Francois Favennec, Eric Rius, Christophe Goujon

“…At a fixed fundamental frequency, this allows the dimensions of the resonators to be modulated to control both the location of the harmonics and the power handling for space applications. …”
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Prioritizing Signaling Information Transmission in Next Generation Networks by Jasmina Baraković, Himzo Bajrić, Mladen Kos, Sabina Baraković, Amir Husić

“…To proof the concept, a simulation study was performed using Network Simulator version 2 (ns-2) and independently developed Session Initiation Protocol (SIP) module. The obtained results were statistically processed using Statistical Package for the Social Sciences (SPSS) version 15.0. …”
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Extrinsic and Intrinsic Regulation of Axon Regeneration by MicroRNAs after Spinal Cord Injury by Ping Li, Zhao-Qian Teng, Chang-Mei Liu

“…Multiple intrinsic and extrinsic factors contribute to the general failure of axonal regeneration after injury. MicroRNAs can modulate multiple genes’ expression and are tightly controlled during nerve development or the injury process. …”
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Application of Natural Antioxidants as Feed Additives in Aquaculture: A Review by Xiaodan Hu, Wenjing Ma, Disen Zhang, Zikun Tian, Yuanqiang Yang, Yi Huang, Yuhang Hong

“…By neutralizing ROS and modulating cellular signaling pathways such as Nrf2/ARE, these compounds offer significant protective effects against oxidative damage in aquatic species. …”
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