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2641
Bibliometric Analysis of Neuroinflammation and Postoperative Cognitive Dysfunction
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2642
ACOX1 activates autophagy via the ROS/mTOR pathway to suppress proliferation and migration of colorectal cancer
Published 2025-01-01“…ACOX1 may regulate autophagy by reprogramming lipid metabolism to modulate the ROS/mTOR signaling pathway, consequently inhibiting the proliferation and migration of CRC.…”
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2643
Giant and flexible toroidal circular dichroism from planar chiral metasurface
Published 2025-01-01“…Facing corresponding challenges in fabrication, integration, and application, it is generally difficult to employ toroidal circular dichroism in compact metasurfaces for flexible modulation of chiral interactions between electromagnetic waves and matter. …”
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2644
Purine-Metabolizing Ectoenzymes Control IL-8 Production in Human Colon HT-29 Cells
Published 2014-01-01“…Interleukin-8 (IL-8) plays key roles in both chronic inflammatory diseases and tumor modulation. We previously observed that IL-8 secretion and function can be modulated by nucleotide (P2) receptors. …”
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2645
Filamented hydrogels as tunable conduits for guiding neurite outgrowth
Published 2025-04-01“…FLight employs optical modulation instability (OMI) to rapidly and safely (<5 s) fabricate hydrogel constructs with precise microfilament alignment. …”
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2646
Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency
Published 2025-02-01“…Previous studies demonstrated that high, rather than low α-defensin level could modulate the local pro-inflammatory milieu of bronchial epithelial cells and macrophages promoting chronic inflammation and lower pathogen phagocytosis. …”
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2647
The Role of Gut Microbiota in Hypertension Management - A Review
Published 2025-02-01“…The state of knowledge: Key mechanisms involved into regulation of blood pressure include the production of short- chain fatty acids (SCFAs), modulation of the renin-angiotensin system (RAS), immune system regulation, and metabolite production such as trimethylamine-N-oxide (TMAO). …”
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2648
The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review
Published 2025-02-01“…Both acute and chronic exercise induce a transient shift in organic homeostasis, modulating the immune system and impacting the balance between Th1 and Th2 cells. …”
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2649
Relativistic Binary Precession: Impact on Eccentric Massive Binary Black Hole Accretion and Hydrodynamics
Published 2025-01-01“…We find that the GR precession of the binary's semimajor axis can introduce a dominant modulation in the binary's accretion rate and the corresponding high-energy electromagnetic light curves. …”
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2650
Theranostic nanoemulsions suppress macrophage-mediated acute inflammation in rats
Published 2025-02-01“…This work opens an avenue for exploring theranostic nanoemulsions as a platform for delivering natural anti-inflammatory products for immune modulation. Graphical abstract…”
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2651
miR-1233-3p Inhibits Angiopoietin-1-Induced Endothelial Cell Survival, Migration, and Differentiation
Published 2025-01-01“…Several reports indicate that these effects of miRNAs on EC functions are mediated through the modulation of angiogenesis factor signaling including that of vascular endothelial growth factor (VEGF). …”
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2652
A Fine-Grained Aircraft Target Recognition Algorithm for Remote Sensing Images Based on YOLOV8
Published 2025-01-01“…Initially, this article designs a local detail feature module to tackle the problem of information loss in shallow networks. …”
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2653
Definition of clinical immunology around the globe
Published 2025-01-01“…Immune cells and immune mediators are now known to participate in the pathogenesis of a wide variety of diseases and therapies based on the modulation of immune function are increasingly used. …”
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2654
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2655
Evaluating the Relationship of GDF-15 with Clinical Characteristics, Cardinal Features, and Survival in Multiple Myeloma
Published 2020-01-01“…It plays a significant role in both physiological and abnormal erythropoiesis and regulates iron homeostasis through modulation of hepcidin. It is abnormally secreted in marrow stromal cells of patients with multiple myeloma (MM), which may reflect the tumor microenvironment. …”
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2656
Short-term effects of follicle-stimulating hormone on immune function, lipid, and vitamin metabolism in transiently castrated men
Published 2025-01-01“…Results: FSH significantly upregulates key proteins involved in the modulation of inflammatory response and innate immune system (P ≤ 0.03) and dysregulates lipid metabolism, evidenced by downregulation of multiple apolipoproteins (P ≤ 0.04) and increased levels of cholesterol and glycerophospholipids (P ≤ 0.03). …”
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2657
Divergent Adsorption Regulation in Metal–Organic Frameworks for Highly Efficient CF4/C2F6 Separation
Published 2025-01-01“…This approach involves the selective shielding of open metal sites and the modulation of channel geometry within an electron‐deficient ligand‐based pore environment, thereby facilitating a C2F6 dense‐packing accommodation mode while weakening the CF4 affinity due to the reduced host‐guest interactions. …”
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2658
Sorafenib enhanced the function of myeloid-derived suppressor cells in hepatocellular carcinoma by facilitating PPARα-mediated fatty acid oxidation
Published 2025-01-01“…Mechanistically, sorafenib promoted the effect and fatty acid uptake ability of MDSCs and modulated peroxisome proliferator-activated receptor α (PPARα)-mediated fatty acid oxidation (FAO). …”
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2659
Advances in the treatment of glioma-related signaling pathways and mechanisms by metformin
Published 2025-01-01“…Metformin’s inhibition of glioma proliferation involves complex cellular processes, including mitochondrial dysfunction, increased reactive oxygen species (ROS) production, and modulation of immune responses. Additionally, metformin affects glioma stem cells by inhibiting key pathways, including STAT3, mTOR, and AKT, and altering the tumor microenvironment. …”
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2660
Mutations in the ARAP3 Gene in Three Families with Primary Lymphedema Negative for Mutations in Known Lymphedema-Associated Genes
Published 2020-01-01“…ARAP3 is a small GTPase-activating protein regulator, which has important functions in lymphatic vessel organogenesis and modulation of cell adhesion and migration. Mutations in the ARAP3 gene are associated with impaired lymphatic vessel formation. …”
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