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2621
Examining the impact of probiotic Lactiplantibacillus pentosus 6MMI on inhibiting biofilm formation, adhesion, and virulence gene expression in Listeria monocytogenes ATCC 19115
Published 2025-06-01“…Additionally, the CFS inhibited the transcription of the plcB, hly, and prfA genes in L. monocytogenes, suggesting a potential reduction in bacterial virulence through decreased hemolysin release and modulation of phospholipase activity. In the next step of the study, the Gaussian Process Regression (GPR) model accurately predicted bile tolerance and acid parameters with a high R2 of 0.99 and minimal Mean Absolute Percentage Error (MAPE) values of 0.33 % and 0.21 %, respectively. …”
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2622
Antiallodynic Effects of Cannabinoid Receptor 2 (CB2R) Agonists on Retrovirus Infection-Induced Neuropathic Pain
Published 2019-01-01“…Diverse types of neuropathic pain respond differently to standard drug intervention, and little is currently known regarding the effects of modulation through CB2Rs. In this study, we evaluated whether treatment with the exogenous synthetic CB2R agonists JWH015, JWH133, Gp1a, and HU308 controls neuropathic pain and neuroinflammation in animals with chronic retroviral infection. …”
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2623
Inhibition of Extracellular Calcium Influx Results in Enhanced IL-12 Production in LPS-Treated Murine Macrophages by Downregulation of the CaMKKβ-AMPK-SIRT1 Signaling Pathway
Published 2016-01-01“…Overall, our study demonstrates a new role of transmembrane calcium mobilization in immunity modulation such that inhibition of calcium influx leads to impaired activation of CaMKKβ-AMPK-SIRT1 signaling pathway which lifts restriction on NF-κB activation and results in enhanced IL-12 production.…”
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2624
Effects of Cranberry Extract (Vaccinium macrocarpon) Supplementation on Lipid Peroxidation and Inflammation in Patients with Chronic Kidney Disease (Stages 3-4): A Randomized Contr...
Published 2024-01-01“…To evaluate cranberry (Vaccinium macrocarpon) supplementation effects on modulation of transcription factors involved in inflammation and oxidative stress in nondialysis (stages 3 and 4) patients with CKD. …”
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2625
Structural and functional connectivity coupling as an imaging marker for bone metastasis pain in lung cancer patients
Published 2025-02-01“…Conclusion: Alterations in SC–FC coupling patterns may play a crucial role in the development and modulation of bone metastasis pain. Understanding these changes could provide valuable insights into the neural mechanisms underlying cancer pain.…”
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2626
Interactions between Leishmania braziliensis and Macrophages Are Dependent on the Cytoskeleton and Myosin Va
Published 2012-01-01“…These data reveal the importance of F-actin, microtubules, and myosin-Va suggesting that modulation of the cytoskeleton may be a mechanism used by L. braziliensis to overcome the natural responses of macrophages to establish infections.…”
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2627
First Report on Microbial-Derived Polydeoxyribonucleotide: A Sustainable and Enhanced Alternative to Salmon-Based Polydeoxyribonucleotide
Published 2025-01-01“…The novel approach of utilizing microbial-derived PDRN opens new avenues for therapeutic applications in oxidative stress management, tissue regeneration, and immune modulation, paving the way for a paradigm shift in PDRN sourcing and functionality.…”
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2628
Cardiovascular and Autonomic Responses after a Single Bout of Resistance Exercise in Men with Untreated Stage 2 Hypertension
Published 2021-01-01“…The aim of this paper is to assess the integrated responses of ambulatory blood pressure (BP), cardiac autonomic modulation, spontaneous baroreflex sensitivity (BRS), and vascular reactivity after a single bout of resistance exercise (RE) in men with stage 2 hypertension who have never been treated before. …”
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2629
Enhanced Influence of Late‐Winter Arctic Oscillation on Early Spring Temperature in North and Northeast Asia
Published 2025-01-01“…Accordingly, the AO exerts a strengthened impact on Mongolian anticyclone and Asian westerly anomalies through modulation of a Rossby wave train that propagates from the Arctic to the NNA in early spring, leading to significant SAT anomalies at NNA. …”
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2630
Impact of commercial gut health interventions on caecal metagenome and broiler performance
Published 2025-01-01“…Conclusions All GHIs are shown to be effective methods for gut microbial modulation, with varying influences on MAG diversity, composition, and microbial functions. …”
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2631
Human Umbilical Cord Mesenchymal Stem Cells Attenuate Ocular Hypertension-Induced Retinal Neuroinflammation via Toll-Like Receptor 4 Pathway
Published 2019-01-01“…The protection is related to the modulation of glial cells, but the mechanisms are still unknown. …”
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2632
Optically levitated nanoparticles as receiving antennas for low frequency wireless communication
Published 2025-01-01“…The effectiveness of these antennas was experimentally demonstrated by using the frequency shift keying (2FSK) modulation scheme. The experimental results indicate a correlation between error rate and factors such as transmission rate, signal strength, and vacuum degree with a signal strength of approximately 0.1V/m and a bit error rate below 0.1%. …”
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2633
Transcriptional activity of repair, apoptosis and cell cycle genes (TP53, MDM2, ATM, BAX, BCL-2, CDKN1A, OGG1, XPC, PADI4, MAPK8, NF-KB1, STAT3, GATA3) in chronically exposed perso...
Published 2022-03-01“…An increased relative content of PADI4 gene mRNA was registered in the group of chronically exposed persons with the increased intensity of early apoptosis (p = 0.006). Modulation of the relative content of mRNA of the TP53 (p = 0.013) and BCL-2 (p = 0.021) genes was detected in the group of chronically exposed individuals with the increased intensity of the late stage of apoptosis. …”
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2634
Novel source/drain contact structure for a-IGZO devices: Oxygen-scavenger-layer metal-interlayer-semiconductor (OSL MIS) approach
Published 2025-01-01“…The proposed OSL MIS contact structure of a-IGZO using OAD modulation technique, shows enormous potential in improving the performance of amorphous oxide semiconductor based advanced electronic devices.…”
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2635
Multidimensional Plasma Lipids Affect Preeclampsia/Eclampsia: A Mendelian Randomization Study
Published 2025-01-01“…Our findings established a causal relationship between specific plasma lipid species and modulation of preeclampsia/eclampsia risk, providing improved resolution for risk assessment and potential therapeutic targets in the disease.…”
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2636
Bone Marrow-Derived Multipotent Stromal Cells Attenuate Inflammation in Obliterative Airway Disease in Mouse Tracheal Allografts
Published 2014-01-01“…Our study suggests that optimal combination of systemic and local delivery of MSCs may ameliorate the development of obliterative airway disease through modulation of immune response.…”
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2637
Ketogenic diet in psychiatry: application in treating depression among athletes
Published 2025-01-01“…The results indicate significant improvements in depressive symptoms, mood stabilization, and mental resilience among individuals adhering to KD. Moreover, KD’s modulation of the gut-brain axis introduces an additional pathway for improving mental health by fostering a diverse gut microbiome and reducing systemic inflammation. …”
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2638
Enhancing Periodontal Ligament Regeneration via PDLSC Delivery Using Electrospun PCL/Collagen/Cellulose Acetate Scaffolds and Collagen Hydrogel Incorporated with Curcumin-Loaded ZI...
Published 2025-01-01“…In vivo efficacy was assessed in a rat PDL injury model using histological and ELISA analyses examining tissue regeneration and inflammatory cytokine modulation.Results: In vitro studies demonstrated that the scaffolds effectively supported PDLSC viability and migration. …”
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2639
A Second Candidate Magnetic Helium Core White Dwarf and 3 Other Variable White Dwarfs in the Globular Cluster NGC 6397
Published 2025-01-01“…One source exhibits a periodic optical modulation of 5.21 ± 0.02 hr, which we interpret as potentially due to the rotation of a magnetic helium core WD (He WD). …”
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2640
Banxia Xiexin Decoction Ameliorates t-BHP-Induced Apoptosis in Pancreatic Beta Cells by Activating the PI3K/AKT/FOXO1 Signaling Pathway
Published 2020-01-01“…BXXD protected MIN6 cells against t-BHP-induced apoptosis and improved insulin secretory function through modulation of the PI3K/AKT pathway and the downstream FOXO1, thus suggesting a novel therapeutic approach for type 2 diabetes mellitus (T2DM).…”
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