Calcium bridges built by mitochondria-associated endoplasmic reticulum membranes: potential targets for neural repair in neurological diseases by Yichen Peng, Li Zhou, Yaju Jin, Danli Wu, Na Chen, Chengcai Zhang, Hongpeng Liu, Chunlan Li, Rong Ning, Xichen Yang, Qiuyue Mao, Jiaxin Liu, Pengyue Zhang

“…These functions can vary significantly across different neurological diseases—such as ischemic stroke, traumatic brain injury, Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, and Huntington’s disease—and their respective stages of progression. Targeted modulation of these disease-related pathways and functional proteins can enhance neurological function and promote the regeneration and repair of damaged neurons. …”
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Analyzing frequency spectrum and Total Harmonic Distortion for high switching frequency operation of GaN-based filter-less multilevel cascaded H-bridge inverter by Ramkrishna Mishan, Xingang Fu, Chanakya Hingu, Poria Fajri

“…This study employs a simulation software PLECS model of the GaN switch to assess symmetric phase-shift pulse width modulation techniques. Later, the efficacy of filterless GaN-based multilevel inverters in diminishing THD is thoroughly investigated using the Texas Instruments microcontroller (TMS320F28335) and the GaN half-bridge EVALUATION BOARD: GS66516T from GaN System Inc. …”
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Lipid-Rich Extract from Mexican Avocado Seed (Persea americana var. drymifolia) Reduces Staphylococcus aureus Internalization and Regulates Innate Immune Response in Bovine Mammary... by Marisol Báez-Magaña, Alejandra Ochoa-Zarzosa, Nayeli Alva-Murillo, Rafael Salgado-Garciglia, Joel Edmundo López-Meza

“…An alternative treatment to control this pathogen is the modulation of the innate immune response of the host. …”
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Linking altered neuronal and synaptic properties to nicotinic receptor Alpha5 subunit gene dysfunction: a translational investigation in rat mPFC and human cortical layer 6 by Danqing Yang, Guanxiao Qi, Daniel Delev, Uwe Maskos, Dirk Feldmeyer

“…Remarkably, it restored nicotinic modulation in neurons of α5SNP rats, while no such effect was observed in α5KO rats. …”
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Crosstalk between non-coding RNAs and programmed cell death in colorectal cancer: implications for targeted therapy by Seyed Reza Taha, Mehdi Karimi, Bahar Mahdavi, Milad Yousefi Tehrani, Ali Bemani, Shahriar Kabirian, Javad Mohammadi, Sina Jabbari, Meysam Hushmand, Alireza Mokhtar, Mohammad Hossein Pourhanifeh

“…Methods A comprehensive literature analysis was conducted to examine recent findings on the role of ncRNAs in modulating various PCD mechanisms, including apoptosis, autophagy, necroptosis, and pyroptosis, and their impact on CRC development and therapeutic response. …”
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Management of Cataract in Patients with Irregular Astigmatism with Regular Central Component by Phacoemulsification Combined with Toric Intraocular Lens Implantation by Yi Gao, Zi Ye, Wenqian Chen, Jinglan Li, Xinlin Yan, Zhaohui Li

“…Some objective indicators of visual quality, including the modulation transfer function (p < 0.05), Strehl ratio (p < 0.005), 100% VA (p < 0.005), 20% VA (p < 0.005), and 9% VA (p < 0.005), were significantly higher than the corresponding preoperative values. …”
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Ameliorative Effect of Hovenia dulcis Fruit Pedicel Polysaccharides on Alcohol-Induced Intestinal Injury in Mice Investigated Using 16S rRNA Sequencing and Metabolomics by ZHANG Yuchao, ZHU Sijie, LIU Liangyu, WANG Jianyun, ZHANG Jiaxin, SU Zexiong, CHEN Jiangyan, LIU Xudong

“…In summary, HDPs has the potential to ameliorate alcohol-induced intestinal damage by improving intestinal barrier function through the modulation of the gut microbiota and bile acid metabolism. …”
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miR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells by Virginie Joris, Elizabeth R. Balmayor, Martijn van Griensven

“…In this work, we aim to evaluate and understand how miR-125b modulates mineralization of hMSCs in two different in vitro models. …”
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The Effects of 1 mA tACS and tRNS on Children/Adolescents and Adults: Investigating Age and Sensitivity to Sham Stimulation by Maike Splittgerber, Jan Hendrik Suwelack, Navah Ester Kadish, Vera Moliadze

“…Finally, our study supports a modulating role of sensitivity to sham stimulation on responsiveness to a broader stimulation and age range.…”
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Liposomal Formulations: A Recent Update by Surendra S. Agrawal, Vrinda Baliga, Vaishali Y. Londhe

“…In addition to drug loading, researchers have focused on spatiotemporal modulation of liposomal carrier medication release. …”
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Adsorption of Mo and O at S-vacancy on ReS2 surface of ReS2/MoTe2 vdW heterointerface by Puneet Kumar Shaw, Jehan Taraporewalla, Sohaib Raza, Akash Kumar, Rimisha Duttagupta, Hafizur Rahaman, Dipankar Saha

“…Here, we emphasize the changes in effective band gap owing to defect-induced states as well as modulation of the energy gap value with Molybdenum (Mo) and Oxygen (O) adsorption at the defect site. …”
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RNAi-based ALOX15B silencing augments keratinocyte inflammation in vitro via EGFR/STAT1/JAK1 signalling by Megan A. Palmer, Rebecca Kirchhoff, Claudia Buerger, Yvonne Benatzy, Nils Helge Schebb, Bernhard Brüne

“…This study suggests a role for ALOX15B in keratinocyte inflammation through modulation of lipid peroxidation and the EGFR/JAK1/STAT1 signalling axis.…”
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Efficacy and compatibility mechanism of bear bile powder in Shexiang Tongxin dropping pills for acute myocardial infarction treatment by Yu Luo, Fangmin Zhang, Lidan Zhu, Jianfeng Ye, Hong-ye Pan, Xiaoyan Lu, Xiaohui Fan

“…Additionally, the combination treatment induced a 62.34% gene reversion rate compared with 55.56% for BBP and 30.20% for CF treatment alone. Modulation of endothelin 1 and growth factor receptor-bound protein 2 was identified as a key synergistic mechanism underlying the anti-AMI effects of BBP in STDP. …”
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Targeting B and T Lymphocyte Attenuator Regulates Lupus Disease Development in NZB/W Mice by Gherardi L, Aubergeon L, Sayah M, Fauny JD, Dumortier H, Monneaux F

“…Regarding its mode of action, we demonstrated that the 6F7 antibody is not a depleting antibody and does not block HVEM binding to BTLA, but instead induces BTLA down modulation and exhibits in vivo agonist activity.Conclusion: Overall, our data confirm the involvement of BTLA in lupus pathogenesis and provide the first evidence that BTLA is a potential therapeutic target for the treatment of lupus.Keywords: systemic lupus erythematosus, BTLA, lupus mice, inhibitory receptors…”
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Association of TNF-α with Impaired Migration Capacity of Mesenchymal Stem Cells in Patients with Systemic Lupus Erythematosus by Linyu Geng, Xia Li, Xuebing Feng, Jiyun Zhang, Dandan Wang, Jinyun Chen, Rui Liu, Haifeng Chen, Lingyun Sun

“…Previous studies indicated that bone marrow mesenchymal stem cells (BMSCs) from patients with systemic lupus erythematosus (SLE) exhibited impaired capacities of proliferation, differentiation, and immune modulation. Considering that migration capacity is important for the exertion of BMSCs functions, the defects in migration might contribute to BMSCs dysfunction in SLE patients. …”
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Inhibition of A2B Adenosine Receptor Attenuates Intestinal Injury in a Rat Model of Necrotizing Enterocolitis by Lie Huang, Juan Fan, Yan-Xiang Chen, Jian-Hui Wang

“…Collectively, our study suggested that the inhibition of A2BR attenuates NEC in the neonatal rat, at least partially through the modulation of inflammation and the induction of epithelial cell proliferation.…”
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Do wolframin, P-glycoprotein, and GRP78/BiP cooperate to alter the response of L1210 cells to endoplasmic reticulum stress or drug sensitivity? by Simona Kurekova, Lucia Pavlikova, Mario Seres, Viera Bohacova, Jana Spaldova, Albert Breier, Zdena Sulova

“…This was associated with increased GRP78/BiP expression and modulation of the expression of several other proteins active in the cellular response to ERS (like CHOP, spliced XBP1, 50-kDa ATF6 protein fragment and others) in P-gp positive cells. …”
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Confronting the anxiety of Generation Z: electroacupuncture therapy regulates oxidative stress and microglia activity in amygdala-basolateral of socially isolated mice by Tong Yin, Junyun Yuan, Lu Liu, Yinxin Wang, Yuanfang Lin, Kangwen Ming, Hang Lv

“…Furthermore, EA was observed to restore normal microglial morphology, indicating its potential role in modulating microglial activity.DiscussionThe results of this study suggest that EA exerts its anxiolytic effects through the modulation of oxidative stress and the activity of microglia in the BLA. …”
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RUNX2 enhances bladder cancer progression by promoting glutamine metabolism by Zhigang Huang, Bin Liu, Xiaoju Li, Chenghua Jin, Quansen Hu, Zhiwei Zhao, Yimin Sun, Qian Wang

“…Overall, this research affirms the crucial function of RUNX2 as a key transcription factor to promoting glutamine and cancer development through modulation of SLC7A6. Targeting RUNX2 could represent a promising therapeutic approach for addressing aberrant glutamine metabolism in bladder cancer.…”
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Comparative Analysis of Freeze-Dried <i>Pleurotus ostreatus</i> Mushroom Powders on Probiotic and Harmful Bacteria and Its Bioactive Compounds by Gréta Törős, Áron Béni, Ferenc Peles, Gabriella Gulyás, József Prokisch

“…OMP-CL, containing the most significant number of CNDs, has shown to be a valuable source for gut microbiota modulation, with its antimicrobial and probiotic-stimulating efficacy. …”
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