Cellular Contractility Profiles of Human Diabetic Corneal Stromal Cells by Thi N. Lam, Sarah E. Nicholas, Alexander Choi, Jian-Xing Ma, Dimitrios Karamichos

“…We tracked, measured, and quantified the contractile footprint over 9 days and quantified the modulation of specific corneal/diabetes markers in the conditional media and cell lysates using western blot analysis. …”
Get full text

Investigation of the Effects of Fosfomycin in Kidney Damage Caused by CLP-Induced Sepsis by Ilknur Esen Yildiz, Tolga Mercantepe, Ilkay Bahceci, Medeni Arpa, Sule Batcik, Yasin Yildiz, Levent Tumkaya

“…The potential mechanisms underlying this protection include the modulation of inflammation, reduction of oxidative stress, and inhibition of apoptosis.…”
Get full text

Comparison of Visual Outcomes and Quality of Life in Patients with High Myopic Cataract after Implantation of AT LISA Tri 839MP and LS-313 MF30 Intraocular Lenses by Jiying Shen, Limei Zhang, Shuang Ni, Lei Cai, Haike Guo, Jin Yang

“…Postoperative uncorrected distance visual acuity (UDVA), best corrected distance visual acuity (BCDVA), uncorrected intermediate visual acuity (UIVA) and uncorrected near visual acuity (UNVA), defocus curve, modulation transfer function (MTF) curve, Strehl ratio (SR), and complications were compared between the two groups. …”
Get full text

Performance Analysis of Iteratively Decoded Convergent Source Mapping with Sphere Packing-Assisted Differential Space-Time Spreading Technique for Efficient Video Transmission by Ishtiaque Ahmed, Nasru Minallah, Jaroslav Frnda, Jan Nedoma

“…We propose an intelligent Convergent Source Mapping (CSM) approach incorporating Differential Space-Time Spreading (DSTS) technique with Sphere Packing (SP) modulation. The crux of CSM process is assured convergence by attaining an infinitesimal Bit-Error Rate (BER). …”
Get full text

The Impact of Zinc Supplementation on the Course of Infections by Justyna Woźniak, Ewelina Kopczyńska, Piotr Kulej, Wiktor Biesiada, Justyna Weronika Kmieć, Anna-Mariia Chernysh, Aleksandra Dusińska, Jakub Waszczyński, Kamila Fuczyło, Karolina Stankevič

“…Results:  Zinc was found to modulate the immune system, influencing T lymphocytes, B lymphocytes, macrophages, and natural killer cells. …”
Get full text

Cognitive Deficit-Related Interhemispheric Asynchrony within the Medial Hub of the Default Mode Network Aids in Classifying the Hyperthyroid Patients by Mengmeng Zhi, Zhenghua Hou, Yuqun Zhang, Yingying Yue, Ling Li, Yonggui Yuan

“…The altered interhemispheric coordination in the hub of the default mode network may implicated in the modulation of episodic memory in HPs patients and the distinct feature of the interhemispheric asynchrony may be treated as a potential target for the early recognition and intervention for the HPs with cognitive impairments. …”
Get full text

FASQuiC: Flexible Architecture for Scalable Spin Qubit Control by Mathieu Toubeix, Eric Guthmuller, Adrian Evans, Antoine Faurie, Tristan Meunier

“…The architecture also provides GHz rate, multiplexed, in-phase and quadrature component, single-side band modulation for scalable reflectometry. This architecture has been validated in hardware on a Xilinx ZCU111 FPGA demonstrating the mixing of complex signals and the quality of the frequency comb generation for multiplexed control and measurement. …”
Get full text

Opposing Roles of Leptin and Ghrelin in the Equine Corpus Luteum Regulation: An In Vitro Study by António Galvão, Angela Tramontano, Maria Rosa Rebordão, Ana Amaral, Pedro Pinto Bravo, Anna Szóstek, Dariusz Skarzynski, Antonio Mollo, Graça Ferreira-Dias

“…Metabolic hormones have been associated with reproductive function modulation. Thus, the aim of this study was: (i) to characterize the immunolocalization, mRNA and protein levels of leptin (LEP), Ghrelin (GHR) and respective receptors LEPR and Ghr-R1A, throughout luteal phase; and (ii) to evaluate the role of LEP and GHR on progesterone (P4), prostaglandin (PG) E2 and PGF2α, nitric oxide (nitrite), tumor necrosis factor-α (TNF); macrophage migration inhibitory factor (MIF) secretion, and on angiogenic activity (BAEC proliferation), in equine corpus luteum (CL) from early and mid-luteal stages. …”
Get full text

Association between Serum Neopterin and Inflammatory Activation in Chronic Kidney Disease by Ashok Kumar Yadav, Vinod Sharma, Vivekanand Jha

“…Its role in future development of cardiovascular disease and modulation with anti-inflammatory therapies needs further studies.…”
Get full text

Ultraviolet spectral broadening by stimulated rotational Raman scattering on nitrogen pumped with signal laser injection by Xiangbing Wang, Xiangxu Chai, Ping Li, Bo Zhang, Qihua Zhu, Xiaocheng Tian, Ju Wang, Zhaoyu Zong, Song Zhou, Ke Yao, Sen Li, Junpu Zhao, Zhitao Peng

“…In addition, high-frequency modulation in the near field can be effectively avoided through replacement of the original random noise signal light by the controllable signal light. …”
Get full text

From botany to bedside: a review of the health benefits of Lycium barbarum as a functional food by Alois Berisha, Elena-Alexandra Alexa, Robbie Kelleher, Tao Zhang

“…Key health benefits include immune modulation, antioxidative effects, mental health support, ocular health preservation, and metabolic and cardiovascular regulation. …”
Get full text

Investigating the role of intratumoral Streptococcus mitis in gastric cancer progression: insights into tumor microenvironment by Ping Yang, Gaoli Liang, Yangyue Ni, Xiaojie Chu, Xiaoshan Zhang, Zhongyu Wang, Adeel Khan, Fangfang Jin, Han Shen, Miao Li, Zhipeng Xu

“…Here, using 16 S rRNA sequencing, tumor tissue proteomics and serum cytokines analysis, we identified enrichment of specific microbial communities within tumors of gastric cancer patients, possibly affecting the tumor microenvironment by immune modulation, metabolic processes, and inflammatory responses. …”
Get full text

Identification of hub genes, non-coding RNAs and pathways in Renal cell carcinoma (RCC): A comprehensive in silico study by Ahmad Golestanifar, Hengameh Khedri, Parisa Noorabadi, Mohammadreza Saberiyan

“…Immune cell infiltration patterns showed significant correlations with hub gene expression, highlighting the importance of immune modulation in KIRC. Conclusion: This research provides a foundation for developing targeted therapies and diagnostic biomarkers for KIRC while underscoring the need for experimental validation to confirm these bioinformatics insights.…”
Get full text

Intratumoral <i>Fusobacterium nucleatum</i> in Pancreatic Cancer: Current and Future Perspectives by Domenica Lucia D’Antonio, Anna Zenoniani, Samia Umme, Adriano Piattelli, Maria Cristina Curia

“…<i>Fn</i> engages in pancreatic tumorigenesis and metastasis through multifaceted mechanisms, including immune response modulation, virulence factors, control of cell proliferation, intestinal metabolite interactions, DNA damage, and epithelial–mesenchymal transition. …”
Get full text

Alpha-linolenic acid-mediated epigenetic reprogramming of cervical cancer cell lines by Amrita Ulhe, Prerna Raina, Amol Chaudhary, Ruchika Kaul-Ghanekar

“…The association of diet with cancer etiology and prevention has been well established and nutrition has been shown to regulate cancer through modulation of epigenetic markers. Dietary fatty acids, especially omega-3, reduce the risk of cancer by preventing or reversing the progression through a variety of cellular targets, including epigenetic regulation. …”
Get full text

Comparative Analysis of Visual Performance and Optical Quality with a Rotationally Asymmetric Multifocal Intraocular Lens and an Apodized Diffractive Multifocal Intraocular Lens by Xiao Wang, Haixia Tu, Yong Wang

“…Ophthalmological evaluation included uncorrected distance visual acuity (UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA), corrected distance visual acuity (CDVA), modulation transfer function (MTF), Strehl ratio (SR), intraocular aberrations (4 mm optical zone), and defocus curve at 3 months postoperatively. …”
Get full text

Changes and Diurnal Variation of Visual Quality after Orthokeratology in Myopic Children by Hao-Chen Guo, Wan-Qing Jin, An-Peng Pan, Qin-Mei Wang, Jia Qu, A-Yong Yu

“…Parameters including corneal curvature, ocular objective scatter index (OSI), the modulation transfer function (MTF), root mean square of ocular and corneal wavefront aberrations, and contrast sensitivity function (CSF) were measured before and at two time points during the same day after 1 month of orthokeratology. …”
Get full text

Effectiveness and Safety of Dupilumab and Tralokinumab for Treating Atopic Dermatitis and Pruritic Skin Disorders in Oncological Patients: A Narrative Review by Lauletta G, Potestio L, Patruno C, De Lucia M, Napolitano M

“…In recent years, biologic agents such as dupilumab and tralokinumab have emerged as promising treatments for AD, offering targeted modulation of the immune response with potentially fewer systemic side effects. …”
Get full text

Exercise‐Activated mPFC Tri‐Synaptic Pathway Ameliorates Depression‐Like Behaviors in Mouse by Tian Lan, Ye Li, Xiao Chen, Wenjing Wang, Changmin Wang, Haiyan Lou, Shihong Chen, Shuyan Yu

“…Abstract Exercise is considered as playing a pivotal role in the modulation of emotional responses. However, a precise circuit that mediates the effects of exercise on depression have yet to be elucidated. …”
Get full text

RETRACTED ARTICLE: Single-cell omics and machine learning integration to develop a polyamine metabolism-based risk score model in breast cancer patients by Xiliang Zhang, Hanjie Guo, Xiaolong Li, Wei Tao, Xiaoqing Ma, Yuxing Zhang, Weidong Xiao

“…The immune profiling and functional enrichment analyses revealed that the genes identified play a crucial role in cell cycle control and immune modulation. Single-cell validation confirmed that polyamine metabolism genes were present in specific cell clusters. …”
Get full text