Toll-like receptors in atopic dermatitis: pathogenesis and therapeutic implications by Ahmad Vafaeian, Fateme Rajabi, Nima Rezaei

“…Current AD treatments like vitamin-D analogs, tacrolimus, and cyclosporine partially work through TLR modulation. Direct TLR stimulation using different compounds has shown therapeutic benefits in preclinical studies. …”
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Secure Communication Scheme Based on a New 5D Multistable Four-Wing Memristive Hyperchaotic System with Disturbance Inputs by Fei Yu, Zinan Zhang, Li Liu, Hui Shen, Yuanyuan Huang, Changqiong Shi, Shuo Cai, Yun Song, Sichun Du, Quan Xu

“…Based on parametric modulation theory and Lyapunov stability theory, synchronization and secure communication between the transmitter and receiver are realized and two message signals are recovered by a convenient robust high-order sliding mode adaptive controller. …”
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Motor Cortex Plasticity during Unilateral Finger Movement with Mirror Visual Feedback by Hatice Kumru, Sergiu Albu, Raul Pelayo, John Rothwell, Eloy Opisso, Daniel Leon, Dolor Soler, Josep Maria Tormos

“…The visual feedback is relevant to M1 cortex excitability modulation but the MVF plays a crucial role in promoting changes in intracortical inhibition in comparison to BVF. …”
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Effect of nanoemulsion carbonated hydroxyapatite-statin administration on Acp 5 and Runx-2 expression during orthodontic relapse in rats by Ananto Ali Alhasyimi, Niswati Fathmah Rosyida, Ika Dewi Ana

“…Pharmacologic bone modulation is a viable approach to mitigate relapse. …”
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Curcumin Protects Neonatal Rat Cardiomyocytes against High Glucose-Induced Apoptosis via PI3K/Akt Signalling Pathway by Wei Yu, Wenliang Zha, Zhiqiang Ke, Qing Min, Cairong Li, Huirong Sun, Chao Liu

“…The function of curcumin on NADPH oxidase-related ROS production and cardiac apoptosis, together with the modulation of protein signalling pathways, was investigated in cardiomyocytes. …”
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Metabolism-Related Adipokines and Metabolic Diseases: Their Role in Osteoarthritis by Zhang Q, Zhao YX, Li LF, Fan QQ, Huang BB, Du HZ, Li C, Li W

“…As key mediators of MetS, metabolic adipokines such as leptin, lipocalin, and resistin regulate inflammation and bone metabolism through distinct or synergistic signaling pathways. Their modulation of inflammatory responses and bone remodeling processes plays a critical role in the pathogenesis and progression of OA. …”
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Beneficial Effects of Probiotic Treatment on Gut Microbiota in Very Low Birth Weight Infants by Yue-feng Li, Chuan-rui Zhu, Xue-lei Gong, Hui-ling Li, Li-kuan Xiong, Ke-jian Wang, Guo-Sheng Liu

“…Further studies are required to shed more light on the characteristics of gut microbiota of VLBW neonates. And the modulation of microbiota should be considered to improve the survival rate of VLBW infants.…”
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Evidence of Presynaptic Localization and Function of the c-Jun N-Terminal Kinase by Silvia Biggi, Lucia Buccarello, Alessandra Sclip, Pellegrino Lippiello, Noemi Tonna, Cristiano Rumio, Daniele Di Marino, Maria Concetta Miniaci, Tiziana Borsello

“…Finally, electrophysiological recordings confirmed the role of JNK in the presynaptic modulation of vesicle release. These data suggest that JNK-dependent phosphorylation of T-SNARE proteins may have an important functional role in synaptic plasticity.…”
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Laxative Effect of Lacticaseibacillus rhamnosus Glory LG12: from the Perspective of the Stem Cell Factor/C-kit Signaling Pathway by XIANG Fangqin, LI Yuxing, LI Bailiang

“…Conclusion: L. rhamnosus Glory LG12 promotes gastrointestinal motility by affecting the release of gastrointestinal regulatory peptides and inflammatory cytokines through the modulation of the SCF/C-kit signaling pathway, thereby alleviating constipation symptoms.…”
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Kinesiology Tape: A Descriptive Survey of Healthcare Professionals in the United States by Scott W Cheatham, Russell T Baker, Thomas E Abdenour

“…Most respondents used KT for post-injury treatment (74%), pain modulation (67%), and neuro-sensory feedback (60%). …”
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Detection Schemes With Low-Resolution ADCs and Spatial Oversampling for Transmission With Higher-Order Constellations in Terahertz Band by Christian Forsch, Peter Zillmann, Osama Alrabadi, Stefan Brueck, Wolfgang Gerstacker

“…Then, we evaluate the symbol error rate (SER) of the different detectors for 16- and 64-ary quadrature amplitude modulation (QAM). The results indicate that there is a noticeable performance degradation of the suboptimal detectors compared to the optimal detector when the constellation size is larger than the number of quantization levels. …”
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On the Dual Role of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) in Human Malignancies by Andreea Calinescu, Gabriela Turcu, Roxana I. Nedelcu, Alice Brinzea, Anastasia Hodorogea, Mihaela Antohe, Carmen Diaconu, Coralia Bleotu, Daniel Pirici, Lucia B. Jilaveanu, Daniela A. Ion, Ioana A. Badarau

“…Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is a glycoprotein belonging to the carcinoembryonic antigen (CEA) family that is expressed on a wide variety of cells and holds a complex role in inflammation through its alternate splicing and generation of various isoforms, mediating intricate mechanisms of modulation and dysregulation. Initially regarded as a tumor suppressor as its expression shows considerable downregulation within the epithelia in the early phases of many solid cancers, CEACAM1 has been linked lately to the progression of malignancy and metastatic spread as various papers point to its role in tumor progression, angiogenesis, and invasion. …”
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Identification of a metabolic brain network characterizing essential tremor by Solange Volnov, Hamzah Baagil, Oliver Winz, Hans-Juergen Kaiser, Sanne Katherina Meles, Joerg Bernhard Schulz, Kathrin Reetz, Felix Manuel Mottaghy, Florian Holtbernd

“…Abstract The neuronal correlate of tremor genesis and cognitive function in essential tremor (ET) and its modulation by deep brain stimulation (DBS) are poorly understood. …”
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TGFβ1 Controls PPARγ Expression, Transcriptional Potential, and Activity, in Part, through Smad3 Signaling in Murine Lung Fibroblasts by Allan Ramirez, Erin N. Ballard, Jesse Roman

“…The ability of TGFβ1 to modulate the transcriptional activity of PPARγ was then tested in NIH/3T3 fibroblasts containing a PPARγ-responsive luciferase reporter. …”
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A Millimeter-Wave Single-Bit Reconfigurable Intelligent Surface With High-Resolution Beam-Steering and Suppressed Quantization Lobe by Aditya S. Shekhawat, Bharath G. Kashyap, Russell W. Raldiris Torres, Feiyu Shan, Georgios C. Trichopoulos

“…We present a 1-bit reconfigurable intelligent surface (RIS) operating at millimeter-wave frequencies that suppresses the undesired grating lobes encountered in binary phase modulation schemes and achieves high resolution beam steering. …”
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A structured exercise regimen enhances autonomic function compared to unstructured physical activities in geriatric horses by Kanokpan Sanigavatee, Chanoknun Poochipakorn, Onjira Huangsaksri, Sipaporn Vichitkraivin, Sireetorn Pakdeelikhit, Wanlapa Chotiyothin, Sirapatch Wongkosoljit, Thita Wonghanchao, Metha Chanda

“…A study involving 27 geriatric horses examined their autonomic modulation over 12 weeks under different activity levels. …”
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Kaempferol enhances ER-mitochondria coupling and protects motor neurons from mitochondrial dysfunction and ER stress in C9ORF72-ALS by Federica Pilotto, Paulien Hermine Smeele, Olivier Scheidegger, Rim Diab, Martina Schobesberger, Julieth Andrea Sierra-Delgado, Smita Saxena

“…Lastly, in silico modelling identified a novel kaempferol target and mechanistically the neuroprotective mechanism of kaempferol is through the iP3R-VDAC1 pathway via the modulation of GRP75 expression. Thus, kaempferol holds great promise for treating neurodegenerative diseases where both mitochondrial and ER dysfunction are causally linked to the pathophysiology. …”
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Butyrate Supplementation Improves Intestinal Health and Growth Performance in Livestock: A Review by Wenting Chen, Qingshan Ma, Yan Li, Lin Wei, Zhenwei Zhang, Adnan Khan, Muhammad Zahoor Khan, Changfa Wang

“…As a short-chain fatty acid, butyrate is known for enhancing intestinal development, improving immune function, and modulating microbial diversity. Studies indicate that butyrate supports gut barrier integrity, reduces inflammation, and optimizes feed efficiency, especially during the critical weaning and post-weaning periods in calves, piglets, and lambs. …”
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Harmonik und Aufführungspraxis by Hubert Moßburger

“…Auf Grundlage dieser Quellen werden folgende Kriterien für die Interpretation von Harmonik zusammengestellt, in ihrem geschichtlichen Wandel untersucht und an Literaturbeispielen belegt: Konsonanz-Dissonanz, Chromatik (tonartfremde Klänge), Enharmonik, Akkordprogression und Modulation. Als musikalische Gestaltungsmittel dieser fünf Interpretationsaspekte stehen Dynamik, Gewichtung (ganzer Akkorde, aber auch von Einzeltönen), Agogik, Intonation und Farbgebung zur Verfügung. …”
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Contrasting Effects of Systemic Monocyte/Macrophage and CD4+ T Cell Depletion in a Reversible Ureteral Obstruction Mouse Model of Chronic Kidney Disease by Lee D. Chaves, Liby Mathew, Mohammed Shakaib, Anthony Chang, Richard J. Quigg, Tipu S. Puri

“…Our results demonstrate that modulation of the inflammatory response during injury and repair altered the susceptibility of C57BL/6 mice to development of CKD in our rUUO model.…”
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