Individual variability in cortical representations of tonic pain by Bettina Deak, Anne Stankewitz, Astrid Mayr, Viktor Witkovsky, Pauline Jahn, Enrico Schulz

“…Therapies to relieve pain that rely on the modulation of brain regions will fail unless they are adapted to an individual's unique pain processing characteristics.…”
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Physiological and pathological roles of PGAM5: An update and future trend by Weibin He, Wenlong He, Zhongchan Sun, Pengcheng He

“…Additionally, we summarize some novel roles of PGAM5 in cellular senescence, lipid metabolism, and immune response modulation in recent studies. Finally, we discuss PGAM5’s contribution to the pathological state of cardiovascular, hepatic, neurological, and neoplastic diseases, offering potential perspectives for future research.…”
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A Novel Platelet Activating Factor Receptor Antagonist Reduces Cell Infiltration and Expression of Inflammatory Mediators in Mice Exposed to Desiccating Conditions after PRK by Salomon Esquenazi, Jiucheng He, Na Li, Nicolas G. Bazan, Isi Esquenazi, Haydee E. P. Bazan

“…To study the contribution of a novel PAF receptor antagonist LAU-0901 in the modulation of the increased inflammatory response in mice exposed to dessicating conditions (DE) after PRK. …”
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Research on SiC Speed Controller for High-Voltage Distributed Electric Propulsion System by Labin Wang, Yunhan He, Yun Xu, Li Fan, Junhua Xiang

“…Second, to solve the challenge of wide battery voltage fluctuation range and inconsistent controller output, an adaptive pulse width modulation (PWM) regulation mode for battery voltage is proposed, ensuring stable controller output. …”
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Eklektizismus und Experiment. ›Just Intonation‹ in Ben Johnstons späten Streichquartetten by Johannes Quint

“…In the 3rd movement of String Quartet No. 9, cycles are altered through microtonal modulation. Microtonal mutations permeate the variations of the 4th movement of String Quartet No. 10 and in the 1st movement of String Quartet No. 8 the diminution of a harmonic progression acquires a new quality due to its abundance of microtonal intervals. …”
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Exploring genetic structures and shared sites between alcohol, cheese intake, and inflammatory bowel disease by Zhifang Huang, Weichao Yuan

“…Furthermore, both conjFDR and MTAG analyses identified multiple shared genetic loci, with nine genes (Y_RNA, DENND1B, GCKR, KPNA7, CLN3, SLC39A8, FUT2, ERAP2, and SMAD3) being.ConclusionThe present study provides genetic evidence supporting the comorbidity of alcohol and cheese intake with IBD, offering novel insights into potential strategies for the prevention and treatment of IBD through the modulation of alcohol and cheese consumption.…”
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Monocarboxylate Transporters: Role and Regulation in Corneal Diabetes by Pawan Shrestha, Amy E. Whelchel, Sarah E. Nicholas, Wentao Liang, Jian-Xing Ma, Dimitrios Karamichos

“…Herein, we reveal the existence and modulation of MCTs in the human diabetic cornea in vitro. …”
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Spontaneous Complete Regression of Colon Cancer Liver Metastases in a Lung Transplant Patient: A Case Report by Koen Zwart, Dieuwertje Ruigrok, Magda de Graaf-Bos, Roel Goldschmeding, Miriam Koopman, Guus M. Bol

“…We describe the spontaneous, complete regression of colon cancer liver metastases, without initiation of antitumor therapy, in a solid organ transplant patient after modulation of immunosuppressants. Case Presentation. …”
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Nonlinear Dynamic Response Analysis of Cable–Buoy Structure Under Marine Environment by Qiufu Xie, Binghan Liu, Junxian Zhang, Yaobing Zhao

“…Galerkin discretization is then employed to construct coupled systems that account for nonlinear buoy motion, as well as decoupled systems assuming linear buoy motion. The modulation equations for the system’s primary resonance response are derived using the method of multiple scales. …”
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Validation of <i>Monilinia fructicola</i> Putative Effector Genes in Different Host Peach (<i>Prunus persica</i>) Cultivars and Defense Response Investigation by Lucia Landi, Annamaria Lucrezia D’Ortenzio, Sarah Mojela Makau, Rita Milvia De Miccolis Angelini, Gianfranco Romanazzi

“…On plants susceptible to brown rot, the pathogen may have adapted to the host’s physiology by modulating its effectors as weapons.…”
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The Role of Vitamin D in the Pathomechanism of Inflammatory Bowel Disease (IBD) and its Therapeutic Implications - a literature review by Wiktoria Maria Tomaszewska, Paweł Siudziński, Mateusz Łyko, Alicja Skoczylas, Jakub Kurasz, Wojciech Maj, Wiktoria Podlasiewicz, Katarzyna Pala, Piotr Dudziak, Anna Nowak, Maria Golińska

“…Its mechanisms of action involve immune system modulation, specifically by reducing the production of pro-inflammatory cytokines, such as IL-6 and TNF-α, while enhancing the levels of anti-inflammatory cytokines, such as IL-10. …”
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Fucoxanthin Inhibits the NMDA and AMPA Receptors Through Regulating the Calcium Response on Substantia Gelatinosa Neurons of the Trigeminal Subnucleus Caudalis in Juvenile Mice by Nhung Ha Thuy Le, Seon Ah Park, Yu Mi Kim, Dong Kuk Ahn, Won Jung, Seong Kyu Han

“…The FCX blockade of NMDA-mediated excitotoxicity was associated with the modulation of Ca2+ response without affecting Na+ ions. …”
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The Effects Of Simvastatin On Islets Of Langerhans In The Pancreas Of Rats: A Histological And Biochemical Study by Abdullah Qamar, Hammad Gul Khan, Hina Kundi, Ayesha Ali, Sumyyia Bashir, Tooba Khurshid

“…These findings suggest potential modulation of pancreatic islet function by simvastatin without affecting glycemic control in this model. …”
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Bi-GRU Enhanced Cost-Effective Memory-Aware End-to-End Learning for Geometric Constellation Shaping in Optical Coherent Communications by Zhiyang Liu, Xiaoyu Liu, Shilin Xiao, Weiying Yang, Weisheng Hu

“…The performance of the proposed system has been numerically verified at a 32 GBd 5-channel wavelength division multiplexing (WDM) 64 quadrature amplitude modulation (QAM) 800 km optical coherent communication system. …”
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SPOCK2 controls the proliferation and function of immature pancreatic β-cells through MMP2 by Katarzyna Blaszczyk, Anna P. Jedrzejak, Natalia Ziojla, Ekaterina Shcheglova, Karolina Szarafin, Artur Jankowski, Christine A. Beamish, Jolanta Chmielowiec, Omaima M. Sabek, Ashok Balasubramanyam, Sanjeet Patel, Malgorzata Borowiak

“…Through bidirectional expression modulation and single-cell RNA-seq, we identified SPOCK2, an ECM protein, as an inhibitor of immature β-cell proliferation. …”
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Peripheral Signals Mediate the Beneficial Effects of Gastric Surgery in Obesity by Silvia Barja-Fernández, Cintia Folgueira, Cecilia Castelao, Rosaura Leis, Felipe F. Casanueva, Luisa M. Seoane

“…The gastrointestinal tract has emerged in the last time as an endocrine organ in charge of response to the different stimulus related to nutritional status by the modulation of more than 30 signals acting at central level to modulate food intake and body weight. …”
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Microiontophoretic Application of Dynorphin in Dental Pain: Excitatory or Inhibitory Effects by Choi SH, Kim YM, Son JY, Ahn DK

“…Thus, dynorphin exerts diverse effects, highlighting its role in the perception and modulation of dental pain.Keywords: dynorphin, N-methyl-D-aspartate, kappa receptor, dental pulp, analgesics…”
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Apoptosis Transcriptional Profile Induced by Porphyromonas gingivalis HmuY by Paulo C. Carvalho-Filho, Lilia F. Moura-Costa, Ana C. M. Pimentel, Mabel P. P. Lopes, Sibelle A. Freitas, Patrícia M. Miranda, Ryan S. Costa, Camila A. V. Figueirêdo, Roberto Meyer, Isaac S. Gomes-Filho, Teresa Olczak, Márcia T. Xavier, Soraya C. Trindade

“…Our data suggest that P. gingivalis HmuY protein might participate differently in the modulation of the intrinsic and extrinsic apoptosis pathways.…”
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Hyperthermia and targeting heat shock proteins: innovative approaches for neurodegenerative disorders and Long COVID by David M. Smadja, David M. Smadja, M. Marc Abreu, M. Marc Abreu

“…Despite the absence of robust clinical trials, the therapeutic implications of WBH extend to immune modulation and the restoration of disrupted physiological pathways. …”
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Decoding communicative action vitality forms in social contexts by Radoslaw Niewiadomski, Radoslaw Niewiadomski, Amrita Suresh, Alessandra Sciutti, Giuseppe Di Cesare, Giuseppe Di Cesare

“…Results indicate that VFs are not merely characterized by a modulation of a single motion parameter such as velocity or acceleration, but by a combination of different spatiotemporal properties. …”
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