Clinical Applications of Heart Rate Variability in the Triage and Assessment of Traumatically Injured Patients by Mark L. Ryan, Chad M. Thorson, Christian A. Otero, Thai Vu, Kenneth G. Proctor

“…Heart rate variability (HRV) is a method of physiologic assessment which uses fluctuations in the RR intervals to evaluate modulation of the heart rate by the autonomic nervous system (ANS). …”
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NEIL3 and TOP2A as key drivers of esophageal cancer through WNT signaling by Hui Li, Panpan Wang, Huijuan Chen, Yanyan Shao, Hui Luo

“…In vivo, NEIL3 knockdown reduced tumor size and weight via WNT pathway modulation. NEIL3 and TOP2A play key roles in EC progression through the WNT signaling pathway. …”
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An Aloe-Based Composition Constituting Polysaccharides and Polyphenols Protected Mice against D-Galactose-Induced Immunosenescence by Mesfin Yimam, Teresa Horm, Alexandria O’Neal, Ping Jiao, Mei Hong, Qi Jia

“…Polysaccharides and polyphenols from botanicals are known for their immune modulation effects. Here we evaluated a standardized mushroom-based composition, UP360, from Aloe barbadensis, Poria cocos, and Rosmarinus officinalis, as a natural nutritional supplement for a balanced immune response in an accelerated aging mouse model. …”
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Q-Switched and Mode-Locked Nd/Cr:YAG Ceramic Pulse Laser by T. Saiki, N. Hirota, S. Kanemori, Y. Iida

“…A single-mode-locked laser pulse with fast modulation on the order of 100 ps was obtained in some pump power regimes when using the Cr4+:YAG crystal. …”
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Investigation of the Physical Properties of Different Ion Species at Hadron Therapy; A Comprehensive Study by Ahmad Esmaili Torshabi

“…Furthermore, in proton therapy, the main source of produced neutrons are passive or active modulation devices located in front of the therapeutic beam. …”
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Action inflexibility and compulsive-like behavior accompany neurobiological alterations in the anterior orbitofrontal cortex and associated striatal nuclei by Laura M. Butkovich, Sophie T. Yount, Aylet T. Allen, Esther H. Seo, Andrew M. Swanson, Shannon L. Gourley

“…We found that these mice also demonstrate insensitivity to Pavlovian-to-instrumental transfer, as well as compulsive-like grooming behavior that is ameliorated by fluoxetine and inhibitory, but not excitatory, chemogenetic modulation of excitatory OFC neurons. Thus, these mice offer the opportunity to identify neurobiological factors associated with inflexible and compulsive-like behavior. …”
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Dissociating the roles of alpha oscillation sub-bands in visual working memory by Na Zhao, Qiang Liu

“…To address this, we employed a whole-field change detection paradigm to investigate how alpha power modulation and decoding accuracy differ between these sub-bands in response to varying set sizes and spatial extents of memory arrays. …”
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Research on UAV Jamming Signal Generation Based on Intelligent Jamming by Haonan Xue, Zhihai Zhuo, Weihao Yan, Yuexia Zhang

“…Without relying on prior signal knowledge, the algorithm introduces complex convolutional networks and residual modules. The model leverages advanced convolutional networks to integrate the real and imaginary components of the signal for feature extraction, while the residual modules further refine signal processing and enhance feature learning. …”
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Engineering extracellular vesicles for ROS scavenging and tissue regeneration by Ahmed Abdal Dayem, Ellie Yan, Minjae Do, Yoojung Kim, Yeongseo Lee, Ssang-Goo Cho, Deok-Ho Kim

“…Insights into EV and ROS signaling modulation pave the way for targeted and efficient regenerative therapies harnessing the potential of EVs.…”
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Decreased Interleukin-4 Release from the Neurons of the Locus Coeruleus in Response to Immobilization Stress by Hyun-ju Lee, Hyun-Jung Park, Angela Starkweather, Kyungeh An, Insop Shim

“…Interleukin-4 (IL-4), an anti-inflammatory cytokine, is known to regulate inflammation caused by immune challenge but the effect of IMO on modulation of IL-4 expression in the brain has not been assessed yet. …”
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Mechanisms of oral ciprofloxacin-induced depressive-like behavior and the potential benefit of lactulose: A correlation analysis by Havizur Rahman, Kusnandar Anggadiredja, Lucy Sasongko

“…This study indicate that ciprofloxacin induce depression-like behavior via modulation of several neurotransmitter system as well as proinflammatory cytokines in the hippocampus and prefrontal cortex. …”
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The ACE2/Apelin Signaling, MicroRNAs, and Hypertension by Lai-Jiang Chen, Ran Xu, Hui-Min Yu, Qing Chang, Jiu-Chang Zhong

“…MicroRNAs are linked with modulation of the ACE2/Apelin signaling, which exhibits beneficial effects in the cardiovascular system and hypertension. …”
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Transcriptome analysis reveals the molecular mechanism of γ-linolenic acid eradicating the biofilm of vancomycin-resistant Enterococcus faecium by Ming Wei, Peng Wang, Tianmeng Li, Jun Liu, Yu Wang, Li Gu, Shuai Wang

“…In addition, KEGG analysis identified specific metabolic pathways that were significantly downregulated by GLA.ConclusionGLA effectively targets multiple aspects of biofilm formation in VRE-fm, including the downregulation of key biofilm-related genes, the inhibition of quorum sensing systems, and the modulation of metabolic pathways. GLA emerges as a promising candidate for eradicating Enterococcus biofilms.…”
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Gut microbiota and atrial cardiomyopathy by Tingting Sun, Beibei Song, Bo Li

“…We focus on the pathophysiological aspects of atrial cardiomyopathy, the impact of gut microbiota dysbiosis on atrial structure and function, and therapeutic strategies exploring modulation of the microbiota for the treatment of atrial cardiomyopathy. …”
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Effect of Antioxidants on the Gut Microbiome Profile and Brain Functions: A Review of Randomized Controlled Trial Studies by Aleksandra Hyży, Hanna Rozenek, Ewa Gondek, Mariusz Jaworski

“…Background: Antioxidants are widely recognized for their potential health benefits, including their impact on cognitive function and gut microbiome modulation. Understanding these effects is essential for exploring their broader clinical applications. …”
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KV1 and KV3 Potassium Channels Identified at Presynaptic Terminals of the Corticostriatal Synapses in Rat by David Meneses, Ana V. Vega, Francisco Miguel Torres-Cruz, Jaime Barral

“…In the last years it has been increasingly clear that KV-channel activity modulates neurotransmitter release. The subcellular localization and composition of potassium channels are crucial to understanding its influence on neurotransmitter release. …”
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Voluntary Spatial Attention has Different Effects on Voluntary and Reflexive Saccades by Stephanie K. Seidlits, Tammie Reza, Kevin A. Briand, Anne B. Sereno

“…In addition, the present study tested the effects of fixation condition (gap, step, and overlap) on attentional modulation. Cueing effects did not vary due to fixation condition. …”
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Abatement by Alhagi maurorum of lead-induced nephrotoxicity in rats: emphasis on Nrf2/HO-1 by Mardi M. Algandaby

“…Conclusion AM guards against Pb-induced nephrotoxicity in rats that involve, at least partly, the antioxidant, anti-inflammatory, and anti-apoptotic activities as well as the modulation of HO-1 and Nrf2 expression.…”
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Effect of Dietary Cholesterol, Phytosterol, and Docosahexaenoic Acid on Astaxanthin Absorption and Retention in Rainbow Trout by Yang Jin, Keshuai Li, Jon Olav Vik, Marie Hillestad, Rolf Erik Olsen

“…In conclusion, this study has suggested that CH promotes Ax absorption by regulating lipoprotein retention and provide evidence for improving Ax absorption via dietary modulation.…”
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A Current Overview of Next-Generation Probiotics and Their Prospects in Health and Disease Management by Ke-Yan Loo, Joanne Yuen Heng Thong, Loh Teng-Hern Tan, Vengadesh Letchumanan, Kok-Gan Chan, Learn-Han Lee, Jodi Woan-Fei Law

“… Traditional probiotics have been extensively studied, and their effectiveness in gut modulation is well established. However, emerging research has shifted focus to previously understudied probiotic strains, now known as next-generation probiotics (NGPs), with the aim of harnessing their unique potential to elicit targeted therapeutic effects in disease management. …”
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