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2241
A Study of the Different Strains of the Genus <i>Azospirillum</i> spp. on Increasing Productivity and Stress Resilience in Plants
Published 2025-01-01“…The most important modes of action of bacterial plant biostimulants on different plants are increasing disease resistance; activation of genes; production of chelating agents and organic acids; boosting quality through metabolome modulation; affecting the biosynthesis of phytochemicals; coordinating the activity of antioxidants and antioxidant enzymes; synthesis and accumulation of anthocyanins, vitamin C, and polyphenols; enhancing abiotic stress through cytokinin and abscisic acid (ABA) production; upregulation of stress-related genes; and the production of exopolysaccharides, secondary metabolites, and ACC deaminase. …”
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2242
ASSOCIATION BETWEEN CHRONIC APICAL PERIODONTITIS AND OXIDATIVE STRESS OR META-INFLAMMATION: A CROSS-SECTIONAL OBSERVATIONAL STUDY
Published 2024-12-01“…However, its cumulative effect with other associated pathologies could impact the overall modulation of the inflammatory response and general homeostasis. …”
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2243
IP3 Receptors, Mitochondria, and Ca2+ Signaling: Implications for Aging
Published 2011-01-01“…Proteins that prevent or promote apoptosis and autophagy can affect intracellular Ca2+ dynamics and homeostasis through binding and modulation of the intracellular Ca2+-release and Ca2+-uptake mechanisms. …”
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2244
Negative Effects of SIGIRR on TRAF6 Ubiquitination in Acute Lung Injury In Vitro
Published 2020-01-01“…SIGIRR knockdown may increase NF-κB activity via TRAF6 regulation by the classical but not the nonclassical NF-κB signaling pathway. Such modulation between TRAF6 and SIGIRR could affect cytokine secretion and exacerbate the immune response; the IL-8, NFKB1, and NFKBIA mRNA levels were reduced after SIGIRR overexpression. …”
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2245
Using Nonlinear Diffusion Model to Identify Music Signals
Published 2021-01-01“…Then, we use the group shift Fourier transform (GSFT) to transform this partial differential equation into a linear homogeneous differential equation system, and then use the series to obtain the solution of the linear homogeneous differential equation system, and finally use the group shift inverse Fourier transform to obtain the noise frequency modulation time-dependent solution of the probability density function of the interference signal. …”
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2246
From Molecule to Patient Rehabilitation: The Impact of Transcranial Direct Current Stimulation and Magnetic Stimulation on Stroke—A Narrative Review
Published 2023-01-01“…This success is attributed to their capacity to enhance cellular neuromodulation. This modulation includes the reduction of the inflammatory response, autophagy suppression, antiapoptotic effects, angiogenesis enhancement, alterations in the blood-brain barrier permeability, attenuation of oxidative stress, influence on neurotransmitter metabolism, neurogenesis, and enhanced structural neuroplasticity. …”
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2247
Tracking Boats on Amazon Rivers—A Case Study with the LoRa/LoRaWAN
Published 2025-01-01“…This protocol allows parameterizable commands (location table, modulation, routing, source and destination DevEUI, and port) to be sent between end devices, providing flexibility in the configuration and management of Internet of Things networks. …”
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2248
Mesenchymal Stem Cells as Immunomodulators in a Vascularized Composite Allotransplantation
Published 2012-01-01“…The mechanisms by which MSCs modulate the immune response are still under thorough investigation, but these most likely involve expression of local factors influencing T-cell regulation, modulation of cytokine expression (e.g., IL-10, TGF-β, TNF-, INF-γ, etc.), and interactions with dendritic or antigen presenting cells. …”
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2249
Potential application of proteolysis targeting chimera (PROTAC) modification technology in natural products for their targeted protein degradation
Published 2022-03-01“…Therefore, it has been demonstrated that the PROTAC technology has broad application in the modulation of the target protein level. In this review, we outlined the advances in PROTAC combined molecule compounds, summarized its quantitative structure-activity relationship, and finally reviewed the methods applied in identifying the target proteins of natural products. …”
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2250
Prominent Naturally Derived Oxidative-Stress-Targeting Drugs and Their Applications in Cancer Treatment
Published 2025-01-01“…The relationship between oxidative stress and cancer has been extensively studied and highlighted, along with its role in various aspects of angiogenesis. The modulation of oxidative levels and the adaptive mechanisms of oxidative stress in cancer systems are attractive research themes for developing anti-cancer strategies. …”
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2251
Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice
Published 2025-01-01“…Intriguingly, mice lacking liver-innervating vagal sensory neurons also exhibit less anxiety-like behavior compared to control mice. Modulation of the liver-brain axis may aid in designing effective treatments for both psychiatric and metabolic disorders associated with obesity and MAFLD.…”
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2252
Digging deeper into necrotizing enterocolitis: bridging clinical, microbial, and molecular perspectives
Published 2025-12-01“…This review consolidates evidence from various biomedical disciplines to elucidate the complex pathogenesis of NEC, integrating insights from clinical, microbial, and molecular perspectives. It emphasizes the modulation of NEC-associated inflammatory pathways by probiotics and novel biologics, highlighting their therapeutic potential. …”
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2253
Polysomnographic Features of Sleep Disturbances and REM Sleep Behavior Disorder in the Unilateral 6-OHDA Lesioned Hemiparkinsonian Rat
Published 2014-01-01“…HP rats showed 30–50% sleep in both phases, less modulation and synchronization to the light schedule (P<0.0001), and more long run lengths of wakefulness (P<0.05). …”
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2254
Effect of Reverse Polarisation of an Electromagnetic Field on the Performance of a Silicon PV Cell
Published 2020-01-01“…This paper investigated, by one-dimensional modelling, the effects of reverse polarisation of an electromagnetic field, generated by an amplitude modulation radio antenna, on the efficiency of a silicon PV cell. …”
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2255
Fine-tuning d-p hybridization in Ni-B x cocatalyst for enhanced photocatalytic H2 production
Published 2025-01-01“…The above consecutive d-band optimization allows for precise modulation of the Hads/Hdes dynamics in the Ni-B x /CdS, ultimately demonstrating a remarkable H2-evolution activity of 13.4 mmol g-1 h-1 (AQE = 56.1 %). …”
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2256
Intracellular Ca2+ Stores and Ca2+ Influx Are Both Required for BDNF to Rapidly Increase Quantal Vesicular Transmitter Release
Published 2012-01-01“…One potential mechanism to initiate BDNF actions is through its modulation of quantal presynaptic transmitter release. …”
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2257
A review of leishmaniasis: current knowledge and future directions of heterocyclic molecules
Published 2024-09-01“…These mechanisms include disruption of cellular processes within the parasite, interference with DNA replication, and modulation of host immune responses. In addition, the article delves into the effects and side effects of drug therapy, providing an in-depth analysis of their impact on patients. …”
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2258
Sestrin2 Signaling Pathway Regulates Podocyte Biology and Protects against Diabetic Nephropathy
Published 2023-01-01“…By suppressing transforming growth factor beta (TGF-β)/Smad and Yes-associated protein (YAP)/transcription enhancer factor 1 (TEF1) signaling pathways in experimental models, Sestrin2 hindered epithelial-mesenchymal transition and extracellular matrix accumulation in diabetic kidneys. Moreover, modulation of the downstream molecules of Sestrin2, for instance, augmentation of AMPK or Nrf2 signaling and inhibition of mTORC1, has been protective in diabetic nephropathy. …”
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2259
Feedback Training Improves Compliance with Sternal Precaution Guidelines during Functional Mobility: Implications for Optimizing Recovery in Older Patients after Median Sternotomy
Published 2021-01-01“…Older patients may not be able to accurately estimate UE arm force used during weight bearing activities, and visual and auditory feedback improves accuracy and also modulation of pectoralis major muscle activation. Results suggest that an instrumented walker and feedback training could be clinically useful for older patients recovering from open heart surgery.…”
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2260
Phytoestrogens Enhance the Vascular Actions of the Endocannabinoid Anandamide in Mesenteric Beds of Female Rats
Published 2012-01-01“…It is concluded that, in the vasculature of female rats, phytoestrogens produced an estrogen-receptor-dependent enhancement of the anandamide-vascular actions that involves the modulation of CGRP levels and appears to be relevant whenever an adrenergic hyperactivity occurs.…”
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