Mesenchymal Stem Cell–Sourced Exosomes as Potentially Novel Remedies for Severe Dry Eye Disease by Carl Randall Harrell, Valentin Djonov, Ana Volarevic, Aleksandar Arsenijevic, Vladislav Volarevic

“…Accordingly, MSC-Exos may modulate the progression of inflammatory eye diseases, including DED. …”
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Central Sensitization-Based Classification for Temporomandibular Disorders: A Pathogenetic Hypothesis by Annalisa Monaco, Ruggero Cattaneo, Maria Chiara Marci, Davide Pietropaoli, Eleonora Ortu

“…Ultralow frequency transcutaneous electrical nerve stimulation (ULFTENS) is extensively used in TMD and in dental clinical practice, because of its effects on descending pain modulation pathways. The Diagnostic Criteria for TMD (DC/TMD) are the most accurate tool for diagnosis and classification of TMD. …”
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N-Acetylcysteine Decreases Myocardial Content of Inflammatory Mediators Preventing the Development of Inflammation State and Oxidative Stress in Rats Subjected to a High-Fat Diet by Klaudia Sztolsztener, Wiktor Bzdęga, Katarzyna Hodun, Adrian Chabowski

“…Arachidonic acid (AA) is a key precursor for proinflammatory and anti-inflammatory derivatives that regulate the inflammatory response. The modulation of AA metabolism is a target for searching a therapeutic agent with potent anti-inflammatory action in cardiovascular disorders. …”
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Effect of Leflunomide on the Abnormal Expression of Lipid Rafts and F-Actin in B Lymphocytes from Patients with Systemic Lupus Erythematosus by Guang Fu Dong, Xiao Zhang, De Ning He, Ling Li, Guang Feng Zhang

“…There were abnormalities in B cell subsets and LRs and F-actin expression of B cell from SLE patients. Modulation of B cell expression of LRs and F-actin by LEF could be a potential therapeutic target for SLE.…”
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Efficacy and Safety of Tracnil™ Administration in Patients with Dermatological Manifestations of PCOS: An Open-Label Single-Arm Study by Ezhil Arasan Ramanan, Sailatha Ravi, K. R. Radha Anbu, Margaret Michael

“…Therefore, we attribute the mechanism of action of Tracnil™ to modulation of receptor sensitivity to sex hormones or other downstream processing events. …”
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Natural compounds in the management of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential by Jingyi Yuan, Zhenmin Li, Yongjiang Yu, Xiuge Wang, Yunyun Zhao

“…Recently, natural compounds have garnered considerable attention due to their efficacy in hormone modulation and minimal toxicity. Substances such as myo-inositol, resveratrol, berberine, and quercetin have shown promise in mitigating PCOS symptoms. …”
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Hyperuricemia-induced complications: dysfunctional macrophages serve as a potential bridge by Wenyi Gu, Wenyi Gu, Jiajing Zhao, Yu Xu, Yu Xu, Yu Xu

“…The second mechanism is the modulation of inflammation, including targeting toll-like receptors (TLRs) and the NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome. …”
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Seminal Fluid-Mediated Inflammation in Physiology and Pathology of the Female Reproductive Tract by Anthonio O. Adefuye, Henry A. Adeola, Kurt J. Sales, Arieh A. Katz

“…SF, in particular, the inflammatory bioactive lipids, and prostaglandins present in vast quantities in SF, have a role in localized immune modulation and regulation of pathways that can exacerbate inflammation in the FMRT. …”
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IUPHAR review: Drug repurposing in Schizophrenia – An updated review of clinical trials by Jihan K. Zaki, Jakub Tomasik, Sabine Bahn

“…These encompassed a broad range of pharmacological mechanisms, including immunomodulation, cognitive enhancement, and hormonal, metabolic, and neurotransmitter modulation. A notable development is the combination of the muscarinic modulators xanomeline, a compound with antipsychotic properties, and trospium, included to mitigate peripheral side effects, now approved by the FDA as the first antipsychotic drug in decades with a fundamentally novel mechanism of action. …”
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Nanostructured Porous Silicon Photonic Crystal for Applications in the Infrared by G. Recio-Sánchez, V. Torres-Costa, M. Manso-Silván, R. J. Martín-Palma

“…In the present work, two-dimensional (2D) and three-dimensional (3D) devices based on nanostructured porous silicon have been fabricated. 2D devices consist of a square mesh of 2 μm wide porous silicon veins, leaving 5×5 μm square air holes. 3D structures share the same design although multilayer porous silicon veins are used instead, providing an additional degree of modulation. These devices are fabricated from porous silicon single layers (for 2D structures) or multilayers (for 3D structures), opening air holes in them by means of 1 KeV argon ion bombardment through the appropriate copper grids. …”
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Optical semantic communication through multimode fiber: from symbol transmission to sentiment analysis by Zheng Gao, Ting Jiang, Mingming Zhang, Hao Wu, Ming Tang

“…We further enhance spectral efficiency by implementing 4-level pulse amplitude modulation (PAM-4), achieving 9.12 bits/s/Hz without decoding errors. …”
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Memory State Dynamics in BEOL FeFETs: Impact of Area Ratio on Analog Write Mechanisms and Charging by Hannes Dahlberg, Oscar Kaatranen, Karl-Magnus Persson, Arto Rantala, Jacek Flak, Lars-Erik Wernersson

“…Constant-pulse writing schemes enable analog threshold voltage modulation by considering the AR, with reduced voltages and faster operation for smaller ARs. …”
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Power Spectral Density and Functional Connectivity Changes due to a Sensorimotor Neurofeedback Training: A Preliminary Study by Juan L. Terrasa, Guzmán Alba, Ignacio Cifre, Beatriz Rey, Pedro Montoya, Miguel A. Muñoz

“…Several studies have shown that subjects can learn to modulate SMR power to control output devices, but little is known about possible related changes in brain networks. …”
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Characteristics of the South China Sea Monsoon from the Onset to Withdrawal before and after 1993/94 by Zhao Xiaofang, Wang Lijuan

“…Further analysis indicates that a strong modulation of SCS intraseasonal oscillation (ISO) on the SCSSM evolution is observed. …”
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Exploring the Mechanisms of Zhenbao Pills in the Treatment of Stroke through Network Pharmacology Combined with Mendelian Randomization by Yanhong Liu, Yunqi Hua, Xiaoe Jia

“…., VEGFA, ARG1, and GATM), including characteristic genes, and the modulation of oxidative stress and inflammation-related pathways. …”
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Recent Advances in the Pathogenesis of Syndromic Autisms by A. Benvenuto, B. Manzi, R. Alessandrelli, C. Galasso, P. Curatolo

“…Metabolic and mitochondrial defects may have toxic effects on the brain cells, causing neuronal loss and altered modulation of neurotransmission systems. Alterations of the neocortical excitatory/inhibitory balance and perturbations of interneurons' development represent the most probable pathogenetic mechanisms underlying the autistic phenotype in Fragile X-Syndrome and Tuberous Sclerosis Complex. …”
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Transcription factor specificity protein (SP) family in renal physiology and diseases by Wei Zhou, Jiaxi Fang, Qingqing Jia, Hanyan Meng, Fei Liu, Jianhua Mao

“…The review further discusses pharmacological modulation of SPs and its implications for treatment. …”
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Application of Delphi method in site selection of desalination plants by M. Sepehr, S.M.R. Fatemi, A. Danehkar, A. Mashinchian Moradi

“…The maps were then integrated based on the modulation importance coefficient and the identified priorities using a linear Delphi model and the final map was reclassified into five categories. …”
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Activation of PPAR𝛾 by Rosiglitazone Does Not Negatively Impact Male Sex Steroid Hormones in Diabetic Rats by Mahmoud Mansour, Elaine Coleman, John Dennis, Benson Akingbemi, Dean Schwartz, Tim Braden, Robert Judd, Eric Plaisance, Laura Ken Stewart, Edward Morrison

“…Peroxisome proliferator-activated receptor gamma (PPAR𝛾) activation decreased serum testosterone (T) in women with hyperthecosis and/or polycystic ovary syndrome and reduced the conversion of androgens to estradiol (E2) in female rats. This implies modulation of female sex steroid hormones by PPAR𝛾. …”
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Faecalibacterium prausnitzii: A Next-Generation Probiotic in Gut Disease Improvement by Xiaoya He, Shuyang Zhao, Yan Li

“…It is reported that intervention with higher richness of F. prausnitzii through dietary modulation, fecal microbiota transplantation, or culture strategy can protect the mice or the subjects from inflammatory diseases. …”
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