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2061
c-Jun-N-Terminal Kinase Signaling Is Involved in Cyclosporine-Induced Epithelial Phenotypic Changes
Published 2012-01-01“…Furthermore, we identified endoplasmic reticulum (ER) stress as a potential mechanism that may participate in the modulation of tubular cell plasticity during CsA exposure. …”
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2062
Investigation of Functional Activity of Cells in Granulomatous Inflammatory Lesions from Mice with Latent Tuberculous Infection in the New Ex Vivo Model
Published 2013-01-01“…It was found that some part of cytokine macrophage producers have carried acid-fast mycobacteria. Detected modulation in dynamics of production of pro-inflammatory cytokines, growth factors, and leukocyte surface markers by granuloma cells has indicated continued processes of activation and deactivation of granuloma inflammation cells during the latent tuberculous infection progress in mice.…”
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2063
A Time(s), space(s) and communication in Castells’s ‘Network Society’*
Published 2022-10-01“…In this context, he distinguishes between ‘the space of places’ and ‘the space of flows’, with the former referring to the historically familiar sense of space as a material precondition of social interaction and of architectural modulation into ‘place’, and the latter to a novel form of spatiality, one that is related to social interaction that has been fundamentally modified by advanced communication technologies and is characterised by simultaneity, regardless of physical distance. …”
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2064
The Extracellular Environment of the CNS: Influence on Plasticity, Sprouting, and Axonal Regeneration after Spinal Cord Injury
Published 2018-01-01“…As such, unlike the peripheral nervous system, the CNS is unable to revert to a “developmental state” to aid neuronal repair. Modulation of these external factors, however, has been shown to promote growth, regeneration, and functional plasticity after injury. …”
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2065
Mesenchymal Stromal Cells and Viral Infection
Published 2015-01-01“…Intensive studies of the immune modulation and tissue regeneration over the past few years have demonstrated the great potential of MSCs for the prevention and treatment of steroid-resistant acute graft-versus-host disease (GvHD), immune-related disorders, and viral diseases. …”
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2066
Advances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple Sclerosis
Published 2015-01-01“…The identification of the features endowing Th17 cells with high pathogenicity in MS is of particular interest, and discoveries in Th17 cell biology and function could lead to the design of new strategies aimed at modulating the immune response in MS. Here, we will discuss recent advances in this field, with particular focus on the mechanisms conferring pathogenicity in MS and their potential modulation.…”
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2067
COSMC-Regulated O-Glycosylation: A Bioinformatics-Driven Biomarker Identification for Stratifying Glioblastoma Stem Cell Subtypes
Published 2024-12-01“…These findings position O-glycosylation, specially, Cosmc as a promising biomarker for distinguishing GSC subclones, with relevance to immune modulation, and ECM dynamics, identifying it as a potential target for novel GBM therapies.…”
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2068
Classification and Characteristics of Pain Associated with Parkinson’s Disease
Published 2016-01-01“…Its different clinical characteristics, variable relationship with motor symptoms, and inconsistent response to dopaminergic drugs suggest that the mechanism underlying pain in PD is complex and multifaceted, involving the peripheral nervous system, generation and amplification of pain by motor symptoms, and neurodegeneration of areas related to pain modulation. Although pain in DP is common and a significant source of disability, its clinical characteristics, pathophysiology, classification, and management remain to be defined.…”
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2069
Cadmium Tolerance and Detoxification Mechanisms of <i>Lentinula edodes</i>: Physiology, Subcellular Distribution, and Chemical Forms
Published 2025-01-01“…Antioxidant enzymes played an important role in cadmium detoxification, as well as functional group modulation. Cadmium was predominantly distributed in the cell wall fraction, and NaCl-extractable cadmium was the main chemical form. …”
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2070
Effect of Hemin on Brain Alterations and Neuroglobin Expression in Water Immersion Restraint Stressed Rats
Published 2016-01-01“…In the brain, the heme oxygenase (HO) system has been reported to be very active and its modulation seems to play a crucial role in the pathophysiology of neurodegenerative disorders. …”
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2071
Oxidative Stress and Heme Oxygenase-1 Regulated Human Mesenchymal Stem Cells Differentiation
Published 2012-01-01“…In this paper, we define HO-1 as a target molecule in the modulation of adipogenesis and osteogenesis from MSCs and examine the role of the HO system in diabetes, inflammation, osteoporosis, hypertension, and other pathologies, a burgeoning area of research.…”
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2072
Concise Review: Mesenchymal Stem Cells Ameliorate Tissue Injury via Secretion of Tumor Necrosis Factor-α Stimulated Protein/Gene 6
Published 2014-01-01“…This suggests that most beneficial effects are largely due to paracrine secretions or cell-to-cell contacts that have multiple effects involving modulation of inflammatory and immune responses. Currently, the therapeutic benefits of MSCs are in part explained by the cells being activated by signals from injured tissues to express an anti-inflammatory protein, tumor-necrosis-factor-α-induced protein 6. …”
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2073
The protective effects of active ingredients from acrorus tatarinowii on sperm and their molecular mechanisms
Published 2025-01-01“…Abstract Purpose To investigate the therapeutic potential of Acrorus tatarinowii in oligoasthenozoospermia and its related mechanism through modulation of the BCL2/Bax/Caspase3 signaling pathway. …”
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2074
Multi-Object Tracking with Predictive Information Fusion and Adaptive Measurement Noise
Published 2025-01-01“…By applying secondary modulation to the suppression scores and dynamically adjusting the suppression threshold using tracking information, our method better retains candidate boxes for occluded objects. …”
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2075
Design and mechanical analysis of a novel modular bionic earthworm robot with upright functionality
Published 2025-01-01“…Initially, we present a bionic robot unit module that is capable of attaining an upright posture. …”
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2076
Reconfigurable scattering by liquid crystal–polymer composite
Published 2025-01-01“…In this work, we investigate the modulation of scattering statistics with a liquid crystal–polymer composite (LCPC) under varying applied voltages. …”
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2077
APWM adapted half‐bridge LLC converter with voltage doubler rectifier for improving light load efficiency
Published 2017-03-01“…Adapting asymmetric pulse‐width modulation (APWM) in a half‐bridge LLC resonant converter with voltage doubler rectifier for improving light load efficiency has been proposed. …”
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2078
The Effect of Taraxacum officinale Hydroalcoholic Extract on Blood Cells in Mice
Published 2012-01-01“…Dandelion has been used as a remedy for anemia, purifing the blood, and providing immune modulation. Therefore, the aim of this study was to investigate the effect of hydro alcoholic extract on blood cells in mice. …”
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2079
Fabrication and Characterization of a W-Band Cylindrical Dielectric Resonator Antenna-Coupled Niobium Microbolometer
Published 2015-01-01“…The detector measured a voltage responsivity of 0.181 V/W at a modulation frequency of 150 Hz. The detector measured a time constant of 1.94 μs. …”
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2080
Detection and Quantization of Bearing Fault in Direct Drive Wind Turbine via Comparative Analysis
Published 2016-01-01“…MuSEnS can manifest fault modulation information adaptively based on the capacity of complex wavelet transform, which enables the weak bearing fault in DDWT to be detected. …”
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