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2041
A Systemic Network Triggered by Human Cytomegalovirus Entry
Published 2011-01-01“…This network contains ten functional modules (i.e., groups of proteins) that coordinately respond to HCMV entry. …”
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2042
A Numerical Method for Analyzing Electromagnetic Scattering Properties of a Moving Conducting Object
Published 2014-01-01“…Numerical results show that the amplitude and frequency of the scattered field suffer a modulation shift. Then the transient scattered field is calculated, and broadband electromagnetic scattering properties of the moving conducting surface are obtained by the fast Fourier transform (FFT). …”
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2043
Targeting TLR/IL-1R Signalling in Human Diseases
Published 2010-01-01“…Given their central role in innate and adaptive immune responses, it is foreseen that pharmaceutical modulation of TLR/IL-1R signalling pathways by these drugs might yield clinical benefits in the treatment of inflammatory and autoimmune diseases.…”
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2044
Role of Hypothalamus in Acupuncture’s Effects
Published 2025-01-01“…Among the brain regions, the hypothalamus, a small yet critical region in the brain, plays a pivotal role in maintaining homeostasis by regulating a wide array of physiological processes, including stress responses, energy balance, and pain modulation. Emerging evidence suggests that acupuncture may exert its therapeutic effects by modulating the activity of the hypothalamus and its associated neural circuits, particularly in relation to pain, stress, and metabolic regulation. …”
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2045
Safeguarding accuracy for CT imaging with industrial robots: Efficient calibration methods for arbitrary trajectories
Published 2025-02-01“…Image quality metrics such as the Modulation Transfer Function, Shannon entropy and Tenengrad variance are utilized to evaluate and compare the reconstruction quality of the various correction and calibration approaches. …”
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2046
Tuning Mechanical Properties of Polymeric Hydrogels Using Orthogonally Functionalized Crosslinkers
Published 2022-01-01“…Short-term temporal modulation of hydrogel moduli, a key factor of the substrates for cell development, was demonstrated and could provide dynamic microenvironment for biological process. …”
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2047
Toxicological Implications of Platinum Nanoparticle Exposure: Stimulation of Intracellular Stress, Inflammatory Response, and Akt Signaling In Vitro
Published 2018-01-01“…However, lower, subtoxic PtNP concentrations were able to elicit multiple stress responses, secretion of proinflammatory cytokines, and modulation of insulin-like growth factor-1 dependent signal transduction. …”
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2048
Advances and Challenges in Islet Transplantation: Islet Procurement Rates and Lessons Learned from Suboptimal Islet Transplantation
Published 2011-01-01“…To facilitate the engraftment of more robust islets suitable for combating the challenging isolation period and proinflammatory transplantation milieu, numerous approaches have been employed to prevent beta-cell dysfunction and death including immune modulation, prevention of apoptosis and hypoxia, as well as stimulation of growth factors, angiogenesis, and reinnervation. …”
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2049
The Cannabinoid Receptor Type 1 Is Essential for Mesenchymal Stem Cell Survival and Differentiation: Implications for Bone Health
Published 2013-01-01“…Overall, these results show the potential for the modulation of the cannabinoid system in cell-based tissue engineered bone regeneration strategies whilst highlighting cannabis use as a potential cause for concern in the management of orthopaedic patients.…”
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2050
Targeting the B-Cell Pathway in Lupus Nephritis: Current Evidence and Future Perspectives
Published 2013-01-01“…B-cells have, in the last decade, emerged as a promising new therapeutic target, as biological treatments successfully attempting B-cell depletion, inhibition of B-cell proliferation and differentiation, or modulation of B-cell function have become bioengineered. …”
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2051
A between-subjects investigation of whether distraction is the main mechanism behind music-induced analgesia
Published 2025-01-01“…In this study, to assess whether music-induced analgesia primarily operates through cognitive modulation, we used the cold pressor task and objectively compared the pain tolerances of participants in a four-group between-subjects design: a music group that listened to a music piece in the absence of any tasks, a music-and-attention-to-music group that listened to the same piece while also rating the arousal levels in the music, a music-and-attention-to-pain group that rated their pain levels while listening to the same piece, and a silence group as control. …”
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2052
Transcranial Alternating Current and Random Noise Stimulation: Possible Mechanisms
Published 2016-01-01“…Transcranial alternating current stimulation (tACS) is a relatively recent method suited to noninvasively modulate brain oscillations. Technically the method is similar but not identical to transcranial direct current stimulation (tDCS). …”
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2053
Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals
Published 2014-01-01“…Being critical in cancer control and progression, the immune system’s appropriate modulation may provide effective therapeutic options. …”
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2054
Liver Protective Effect of Fenofibrate in NASH/NAFLD Animal Models
Published 2022-01-01“…Fenofibrate is a fibrate drug approved for dyslipidemia that could be used for modulation of hepatic fat accumulation, targeting peroxisome proliferator-activator receptors, and de novo lipogenesis. …”
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2055
Path Formation Time in the Noise-Limited Fractionated Spacecraft Network with FDMA
Published 2018-01-01“…Taking frequency division multiple access (FDMA) with subcarrier binary phase-shift keying (BPSK) modulation as an example, this paper focuses on the issues of constraint to orbital elements and path formation time for the noise-limited fractionated spacecraft network percolating. …”
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2056
Thermotunable Terahertz Negative-Index Metamaterials with Dielectric Spheres Embedded in Semiconductor Host
Published 2018-01-01“…Furthermore, the effects of the radius of the dielectric sphere on the modulation frequency and bandwidth are discussed. Finally, we find that the design parameters for the composites can be scaled for application in the higher frequency regions.…”
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2057
Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells
Published 2015-01-01“…This review will focus on Mtb interactions with human macrophages, dendritic cells, neutrophils, and NK cells and detail evidence that Mtb modulation of these cells negatively impacts Mtb-specific immune responses. …”
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2058
Long COVID and gut microbiome: insights into pathogenesis and therapeutics
Published 2025-12-01“…Recent clinical trials have indicated that gut microbiome modulation using probiotics, prebiotics, and fecal microbiota transplantation (FMT) led to improvements in multiple symptoms related to PACS, including fatigue, memory loss, difficulty in concentration, gastrointestinal upset, and disturbances in sleep and mood. …”
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2059
Fault-Tolerant Control Strategy for Neutral-Point-Clamped Three-Level Inverter
Published 2018-01-01“…An improved Space Vector Pulse Width Modulation (SVPWM) strategy called “addition and subtraction substitution SVPWM” is proposed to effectively suppress fluctuation in capacitor neutral-point voltages by readjusting the sequence and action time of voltage vectors. …”
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2060
Differential Measurement for Cavity Ring-Down Spectroscopy with Dynamic Allan Variance
Published 2020-01-01“…In order to minimize influences of time-varying noises in CRDS, a practical differential measurement method is proposed, in which wavelength modulation is applied to detect the ring-down times at the absorption peak and the nonabsorption peak in a time-division manner. …”
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