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2021
Role of dietary and nutritional interventions in ceramide-associated diseases
Published 2025-01-01“…Although pharmacological inhibition of ceramide formation often protects against these diseases in animal models, pharmacological modulation of ceramides in humans remains impractical. …”
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2022
Role of macrophage in intervertebral disc degeneration
Published 2025-01-01“…To gain a deeper understanding of the inflammatory microenvironment of intervertebral disc degeneration, this review will summarize the role of macrophages in the pathological process of intervertebral disc degeneration, analyze the regulatory mechanisms involving macrophages, and review therapeutic strategies targeting macrophage modulation for the treatment of intervertebral disc degeneration. …”
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2023
PPARG Epigenetic Deregulation and Its Role in Colorectal Tumorigenesis
Published 2012-01-01“…Its function in colon carcinogenesis has largely been debated; accumulating evidence, however, supports a role as tumor suppressor through modulation of crucial pathways in cell differentiation, apoptosis, and metastatic dissemination. …”
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2024
A Pilot Study of Obesity Management: Contributions of Cognitive-Behavioral Group Therapy to Stress, Anxiety, and Emotional Eating
Published 2025-01-01“…After six weeks, the CBGT group had lower scores for emotional and uncontrolled eating, along with an increase in parasympathetic modulation and a decrease in cortisol levels. These results suggest that CBGT may hold potential for improving emotional regulation and reducing emotion-based eating behavior; however, further research is needed to confirm its effectiveness. …”
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2025
Synaptic Wnt/GSK3β Signaling Hub in Autism
Published 2016-01-01“…Furthermore, we integrate information supporting the role of the glycogen synthase kinase 3β (GSK3β) in the onset/development of ASDs through direct modulation of Wnt/β-catenin signaling. Finally, given GSK3β activity as key modulator of synaptic plasticity, we explore the potential of this kinase as a therapeutic target for ASD.…”
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2026
Exploring the Potential of Postbiotics for Food Safety and Human Health Improvement
Published 2024-01-01“…Findings suggest that postbiotics hold promise for improving health and preservation by inhibiting pathogenic bacteria growth and modulating immune responses.…”
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2027
A novel multiple directional shearing interferometry system with synchronous polarization phase shifting
Published 2025-01-01“…The characteristics of crystal birefringence beam modulation, phase grating diffraction, and the polarization phase-shifting array for synchronous phase-shifting interferometry are investigated, based on the specific implementation methods of multi-directional shearing and synchronous polarization phase-shifting. …”
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2028
Clocking In Time to Gate Memory Processes: The Circadian Clock Is Part of the Ins and Outs of Memory
Published 2018-01-01“…Learning, memory consolidation, and retrieval are processes known to be modulated by the circadian (circa: about; dies: day) system. …”
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2029
MIMO SAR Using Orthogonal Coding: Design, Performance Analysis, and Verifications
Published 2015-01-01“…A ground-based MIMO SAR imaging system with up and down chirp modulation is also designed. The performances of MIMO SAR and SISO SAR are compared, and the validity and advantage of MIMO SAR are verified.…”
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2030
RESEARCH ON UNDERWATER COMMUNICATION AND SIMULATED ASSESSMENT OF MAIN PARAMETERS
Published 2018-07-01“…This article presents the basics of underwater communications including the general basis for conducting underwater communications, simulation of an underwater information system using QPSK modulation technique, and conclusion and recommendations for further research.…”
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2031
P2X7 Receptor Function in Bone-Related Cancer
Published 2012-01-01“…Modulation of tumor microenvironment by different mediators is central in determining neoplastic formation and progression. …”
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2032
Divalent Metal- and High Mobility Group N Protein-Dependent Nucleosome Stability and Conformation
Published 2010-01-01“…Our findings emphasize the importance of divalent metals in nucleosome dynamics and suggest that the differential biological activities of HMGNs in chromatin activation may involve different conformational alterations and modulation of nucleosome core stability.…”
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2033
OCT-Precoding Combined with LDPC-Coding Scheme for 128 QAM MB-OFDM UWBoF System
Published 2020-01-01“…In this paper, we proposed a coding scheme based on orthogonal cyclic transpose (OCT) precoding combined with low-density parity check (LDPC) code to improve the transmission performance of 128-quadrature amplitude modulation multiband orthogonal-frequency-division-multiplexing ultrawide band over fiber (128 QAM MB-OFDM UWBoF) system. …”
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2034
Plasticity of Neuron-Glial Transmission: Equipping Glia for Long-Term Integration of Network Activity
Published 2015-01-01“…In recent years, glial cells (most notably astrocytes) have been recognized as active participants in the modulation of synaptic transmission and synaptic plasticity, implicating these electrically nonexcitable cells in information processing in the brain. …”
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2035
Flexible terahertz beam manipulation and convolution operations in light-controllable digital coding metasurfaces
Published 2025-02-01“…We also achieve dynamic modulation of vortex electromagnetic waves based on wireless light-controllable coding metasurfaces. …”
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2036
Cell migration in dense microenvironments
Published 2023-09-01“…The crosstalk between extracellular mechanical inputs and the cell nucleus is a critical component in the modulation of cell function of cells that navigate within packed microenvironments. …”
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2037
A comprehensive review on the effects of green tea and its components on the immune function
Published 2022-09-01“…Green tea and its bioactive components possess many health-promoting and disease-preventing benefits, especially anti-inflammatory, antioxidant, anticancer, and metabolic modulation effects with multi-target modes of action. …”
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2038
Regulatory T Cells in Autoimmune and Viral Chronic Hepatitis
Published 2015-01-01“…With the recent advent of monoclonal antibodies able to target regulatory T cells (daclizumab) and improve immune responses and several ongoing clinical trials analysing the impact of regulatory T cell infusion on autoimmune liver disease or liver transplant tolerance, modulation of immunological tolerance through CD4+ regulatory T cells could be a key element of future immunotherapies for several liver diseases allowing restoring the balance between proper immune responses and tolerance.…”
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2039
Depth-Adaptive Air and Underwater Invisible Light Communication System with Aerial Reflection Repeater Assistance
Published 2025-01-01“…The system employs a mirror-equipped aerial drone as a relay between underwater drones and a terrestrial station, using 850 nm optical signals for low atmospheric loss and enhanced confidentiality. Adaptive modulation optimizes transmission capacity based on SNR, accounting for air and underwater channel characteristics. …”
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2040
Immune Challenge Alters Reactivity of Hippocampal Noradrenergic System in Prenatally Stressed Aged Mice
Published 2019-01-01“…We investigated the contribution of adrenergic receptors to the modulation of hippocampal synaptic plasticity of aged mice and found that impaired LTP in the PS-LPS group was indeed rescued by application of isoproterenol (a nonspecific noradrenergic agonist). …”
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