The Uncoupling of Disease Activity from Joint Structural Progression in Patients with Rheumatoid Arthritis Treated with Filgotinib by Yoshiya Tanaka, Tatsuya Atsumi, Daniel Aletaha, Hendrik Schulze-Koops, Haruhiko Fukada, Chris Watson, Tsutomu Takeuchi

“…Abstract Introduction While modern treatments can prevent progressive bone destruction in patients with rheumatoid arthritis (RA) achieving clinical remission, it is unclear whether residual clinical activity may cause or be associated with progressive joint damage. …”
Get full text

US Deterrence against Russia and China (based on strategic documents of J. Biden administration) by V. I. Batyuk

“…This primarily concerns the quantitative, rather than qualitative side of the equation: according to the US military strategists, Russia has made significant progress in modernizing its strategic nuclear forces and developing fundamentally new types of nuclear delivery vehicles. …”
Get full text

TÜRKİYE’DE 6360 SAYILI BÜYÜKŞEHİR YASASI KAPSAMINDA BÜYÜKŞEHİRLER/ BÜTÜNŞEHİRLER: YÖNETSEL YAPI, MALİ/İKTİSADİ BOYUT ve GELECEK VİZYONU ÜZERİNE BİR TARTIŞMA... by Gökhan Kalağan

“…Büyükşehir kavramı, tarihte ilk kez Eski Yunan’da, metropolis (ana) ve polis (kent) kelimelerinin birleşiminden oluşan metropol (anaşehir) olarak, modern çağda ise Avrupa’da göç ve endüstrileşme ile nüfusu hızla büyüyen Londra, Paris, Roma gibi kentler için kullanılmıştır. …”
Get full text

Solving Nonlinear Energy Supply and Demand System Using Physics-Informed Neural Networks by Van Truong Vo, Samad Noeiaghdam, Denis Sidorov, Aliona Dreglea, Liguo Wang

“…However, the method utilizing neural networks is considered a modern and promising approach, as it effectively exploits the superior computational power of advanced computer systems, especially in solving complex problems. …”
Get full text

Advancing CNS Therapeutics: Enhancing Neurological Disorders with Nanoparticle-Based Gene and Enzyme Replacement Therapies by Liu S, Li H, Xi S, Zhang Y, Sun T

“…Shuhan Liu,1– 3 Haisong Li,4 Shiwen Xi,1,2 Yuning Zhang,1,2,* Tianmeng Sun1,2,5,6,* 1Key Laboratory of Organ Regeneration and Transplantation of Ministry of Education, Institute of Immunology, The First Hospital, Jilin University, Changchun, Jilin, People’s Republic of China; 2National-Local Joint Engineering Laboratory of Animal Models for Human Diseases, Changchun, People’s Republic of China; 3Cancer Center, The First Hospital, Jilin University, Changchun, Jilin, People’s Republic of China; 4Department of Neurosurgery, The First Hospital, Jilin University, Changchun, Jilin, People’s Republic of China; 5International Center of Future Science, Jilin University, Changchun, People’s Republic of China; 6State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun, People’s Republic of China*These authors contributed equally to this workCorrespondence: Tianmeng Sun; Yuning Zhang, The First Hospital of Jilin University, 71 Xinmin St, Changchun, Jilin, People’s Republic of China, Email tsun41@jlu.edu.cn; zhangyuning@jlu.edu.cnAbstract: Given the complexity of the central nervous system (CNS) and the diversity of neurological conditions, the increasing prevalence of neurological disorders poses a significant challenge to modern medicine. These disorders, ranging from neurodegenerative diseases to psychiatric conditions, not only impact individuals but also place a substantial burden on healthcare systems and society. …”
Get full text

Requirements for Police Officer’s Personality in Terms of Globalization and the Implementation of International Standards of Law Enforcement Officers’ Conduct by D. V. Shvets, N. O. Rastorguyeva

“…The tasks are to determine the list of topical issues that should be taken into account during the training of police officers, and to outline the main characteristics of a modern police officer in accordance with international standards of law enforcement officer’s conduct. …”
Get full text

Exogenous Application of Lanthanum Chloride to Rice at Booting Stage Can Increase Chlorophyll Content, Modulate Chlorophyll Fluorescence and Promote Grain Yield Under Deficit Irrig... by Peng Liu, Xilin Fang, Yue Wang, Xin Yang, Qiang Li

Get full text

CULTURAL REPRESENTATION IN THE PRACTICE OF ANDRAGOGY IN THE ACADEMIC by Janawi, Yusra Jamali, Dinar Pratama, Musa, Saiful Anwar, Subardi

“…Recommendations include revising curricula to better reflect andragogical principles, investing in modern learning facilities, and fostering a culture of innovation among lecturers. …”
Get full text

A Massively Parallel SMC Sampler for Decision Trees by Efthyvoulos Drousiotis, Alessandro Varsi, Alexander M. Phillips, Simon Maskell, Paul G. Spirakis

“…A widely used approach to reducing an algorithm’s runtime is to employ modern multi-core computer architectures, either with shared memory (SM) or distributed memory (DM), and use parallel computing to accelerate the algorithm. …”
Get full text

“Old” and “New” Trust in Higher Education by P. A. Ambarova, G. E. Zborovsky, N. V. Shabrova

“…Today, the crisis of modern higher school and processes of its modernisation are followed by the crisis of institutional, inter-community and interpersonal trust, which has remained a fundamental basis of a high school system of vocational education for a very long time. …”
Get full text

Development and evaluation of a novel E7 multi-epitopic vaccine for human papillomavirus type 16: design, expression, purification, and immunological characterization by Bahareh Bahmani, Zahra Amini-bayat, Mohammad Mehdi Ranjbar, Masoud Hassanzadeh Makoui, Amir-Hassan Zarnani

“…Although preventative vaccines have shown significant efficacy in preventing HPV infection, cervical cancer is a significant public health issue that affects millions of women worldwide. Modern therapeutic approaches, such as peptide vaccines, could be promising and have potential for the treatment of the HPV-infected population. …”
Get full text

Design and assembly of plant-based COVID-19 candidate vaccines: reсent development and future prospects by E. A. Uvarova, P. A. Belavin, E. V. Deineko

“…The world scientific community is making tremendous efforts to develop means of protection, prevention and treatment of this disease based on modern advances in molecular biology, immunology and vaccinology. …”
Get full text

ŞEHİR FELSEFESİ YAPMANIN İMKÂNI: ÜSKÜP ÜZERİNE KÜLTÜREL VE FELSEFÎ NOTLAR by Şahin Efil

“…Bu anlamdaÜsküp’ün klasik ve modern mimariyi bir araya getirmesi ve buluşturması, mimari açıdanbu şehre farklılık, çeşitlilik ve zenginlik katmaktadır. …”
Get full text

Fundamentals for forage crop breeding and seed production in Russia by V. M. Kosolapov, V. I. Cherniavskih, S. I. Kostenko

“…During the existence of the Fodder Research Institute and its experimental stations, up to 300 varieties of feed crops were created, which occupied leading positions in the production of fodder in meadows, pastures, and hayfields. Eighty-five modern varieties of fodder crops of the latest generation are widely used and zoned in all regions of Russia. …”
Get full text

Specific Features of the Formation and Development of Mediation in Foreign Countries with Anglo-Saxon and Romano-Germanic Legal Systems by S. S. Myrza

“…According to the chosen topic, the purpose of this scientific article is to consider the modern system of training mediators in developed countries with different legal systems, their comparative analysis in the context of common methods and techniques of training mediators in the world practice, with further implementation of international experience of developed countries in Ukraine, as well as perspectives for applying mediation as an independent way of resolving legal disputes in Ukraine. …”
Get full text

Air Transport Area as an Object of State Regulation by O. V. Brusakova

“…It is established that the state, realizing the importance of state support for the planning and development of modern innovative high-tech air transport, takes appropriate steps in this direction; the specified steps are outlined. …”
Get full text

Community’s Perception and Attitude towards People with Epilepsy in Ethiopia by Wubalem Fekadu, Tesfa Mekonen, Shemelash Bitew, Tefera Chanie Mekonnen, Melak Menberu, Seble Shewangizaw

“…In multivariable analysis, understanding the illness as a medical problem was associated with perceived susceptibility and perceived benefit of modern treatment was significantly associated with having a current medical problem. …”
Get full text

Solar Power Generation in Smart Cities Using an Integrated Machine Learning and Statistical Analysis Methods by Ahmad Almadhor, K. Mallikarjuna, R. Rahul, G. Chandra Shekara, Rishu Bhatia, Wesam Shishah, V. Mohanavel, S. Suresh Kumar, Sojan Palukaran Thimothy

“…Megacity electricity generation is regarded as a current research problem in the modern features of urban administration, particularly in developing nations such as Iran. …”
Get full text

Internal Benchmarking of Thermal Power Plants оf Electric Power Systems by E. M. Farhadzadeh, A. Z. Muradaliyev, Y. Z. Farzaliyev, U. K. Ashurova

“…Improving the operational efficiency (OE) of thermal power plants is one of the most important problems of electric power systems (EPS). According to modern concepts, efficiency is the simultaneous consideration of three properties of objects, viz. economy, reliability and safety. …”
Get full text

Significance of immune factors in Crohn's disease development by D. S. Stavtsev, T. A. Astrelina, O. V. Knyazev, T. V. Pukhlikova

“…The aim of review. To analyze modern approach to pathogenesis of Crohn's diseases (CD), to determine effect of individual immunogenetic factors on development and progression of disease, in particular, in relation to HLA profile.Summary. …”
Get full text